New blog post: How to Not Make a Scientific Journal by Accident pracheeac.substack.com/p/how-to-not...

After working closely together across two open science orgs over the last 7+ years, I’ll really miss working with @jessicapolka.bsky.social. She’s a total pro, an exceptional operator, a sharp strategist, and just a fantastic human ❤️. Really excited to see all she does next!

Spoke recently to the great folks at the science foundation on their efforts to fund curiosity-driven science. They have a new RFA out for catalytic awards (up to $10K). Take a look if you’re itching to expand or try out a new idea. science-foundation.org

Deadline today!!!

ICYMI: the deadline to nominate a publishing trailblazer so we can amplify their efforts is October 31!

ICYMI: Read our impact story on policies at HHMI, Gates & Astera promoting #OpenAccess #OpenScience #OpenData. Thought leaders helping accelerate discovery in science @madubs.bsky.social @openaccessmaven.bsky.social @pracheeac.bsky.social! sparcopen.org/impact-story...

We have a bunch of new job ads out @arcadiascience.com. If you haven’t checked them out, take a look! www.arcadiascience.com/careers

We have a bunch of new job ads out @arcadiascience.com. If you haven’t checked them out, take a look! www.arcadiascience.com/careers

1/ 📢 New blog post! @pracheeac.bsky.social recently wrote a great piece about the need for paradigm shifts in science communication: “Stop building faster horses when we need fundamentally different vehicles.” 🧵https://bsky.app/profile/pracheeac.bsky.social/post/3m2exwtn6o22i

🚨New job alert! We’re trying to put some tailwind behind developing out some of our new molecular, organismal, and high dimensional phenotyping capabilities @arcadiascience.com and are launching an effort to fuel the fire. But first I need a project director to oversee it.

Woah just discovered this formatmypaper.com

Waiting for incentives to change in scientific publishing? We’ve got you! I hope other funders follow suit to make the most of their research dollars

Some scientists aren’t waiting for journals to catch up. They’re showing us what’s next. The Beyond the Journal awards honor those breaking the mold in how science is shared. More details: pracheeac.substack.com/p/off-roadin... Nominate or self-nominate here: www.experiment.foundation/beyond

Some scientists aren’t waiting for journals to catch up. They’re showing us what’s next. The Beyond the Journal awards honor those breaking the mold in how science is shared. More details: pracheeac.substack.com/p/off-roadin... Nominate or self-nominate here: www.experiment.foundation/beyond

New Blog Post: Scholarly Communication Is a Research Problem. This Means You. pracheeac.substack.com/p/scholarly-...

New Blog Post: Scholarly Communication Is a Research Problem. This Means You. pracheeac.substack.com/p/scholarly-...

A serious and useful thread with permission to take AGI seriously by @jascha.sohldickstein.com over at X x.com/jaschasd/sta...

Ordered a shirt that reminds me unambiguously of @richardsever.bsky.social 😂

So @mbeisen.bsky.social and I wrote this not just to sway HHMI to stop walking the tightrope to make all parties comfortable and be clear about their trajectory but because it’s in all scientist’s hands to decide what they want to do open.substack.com/pub/thescien...

Right now is the best chance the scientific community has ever had to end the artificial scarcity of academic journals. 1/

Right now is the best chance the scientific community has ever had to end the artificial scarcity of academic journals. 1/

While journal publishing has always been deeply problematic, hurting both the pace and trajectory of science, something is happening in this moment that is finally causing the system to crumble under its own weight and cost. 1/

Why hasn't Preprint Peer Review caught on more? I discovered a small, but simple reason - authors are missing out on the JOY of getting feedback because they aren't notified when feedback occurs. more in thread below!

Open science projects: Project diffUSE: diffuse.science OpenADMET: openadmet.org @diffuseproject.bsky.social @openadmet.bsky.social @seemaychou.bsky.social @pracheeac.bsky.social @jchodera.bsky.social

TTPD #6 with @fraserlab.com. We chatted about the recent meetings, latest news, open science, social media, and, of course, the recent engagement. podcasts.apple.com/us/podcast/e... wankowiczlab.com/2025/08/31/T...

Just declined to participate in the “biotech, pharma, & curiosity-driven labs” panel at @ascbiology.bsky.social this year because I am not sure I’ll attend (the 1st ASCB meeting I’ll have skipped in 15 years). That said, we’re actively recruiting @arcadiascience.com from this community/skillset…

We’re excited to share @tracykteal.bsky.social will be the new CEO of openRxiv. 🎉 A scientist & nonprofit leader, she has served as Interim COO since launch. Her appointment signals continuity in leadership & our commitment to independence, transparency & open science. openrxiv.org/announcing-c...

Was fantastic to have @ronent.bsky.social @cosmik.network as an open science fellow at @asterainstitute.bsky.social! Excited to see how they’ll progress!

Thrilled we're getting tons of interest from the community looking to follow along and participate! We'll be working on a concerted effort to keep in touch with folks – but for now, if you're interested, please get in touch via the google form in the post below so we can learn a bit more about you!

Open science can sometimes been seen as a risk but IME there are definitely people out there doing research more openly to advance science despite that. 1/4

Happy @diffuseproject.bsky.social launch day! Check out our latest effort. We're grappling with how to better understand protein dynamics and capture/share the information that would best allow the community to make use of that data. Take a look!

Encourage following @ryan-york.bsky.social who is new to this site & our Head of Platform at Arcadia. When we say we aim to leverage the structure of biology (evolution) to inform hypotheses & test them efficiently, what does that mean? Ryan runs the part of the org that develops those solutions

We’re growing @arcadiascience.com & are on the lookout for talent to run new pilot projects contributing to our broader goals. Seeking computational + wet lab fluency to iterate independently on new projects. If you’re a creative scientist w/ ambitious ideas, apply! jobs.lever.co/arcadiascien...

Basic science in the private sector for the benefit of human health? We hope this is just the beginning! Check out our latest effort @arcadiascience.com to help match genes of interest with research organisms using Zoogle! zoogle.arcadiascience.com Blog post: arcadiascience.com/blog/zoogle

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

New job @arcadiascience.com! Ideally you've got a few years of experience post-PhD, in academia or elsewhere, and have some computational fluency in addition to experimental expertise. Added bonus, you'd get to join our pastry-fueled preprint comment parties like the one we're having today :)

🚨Job Alert @arcadiascience.com! Are you an independent, generative, rigorous scientist that can pivot quickly? Can you apply your unique skills to a wide range of bio & tech problems? Can you work with other stellar scientists skilled in orthogonal domains? Join us! jobs.lever.co/arcadiascien...

Deadline extended! Join us!

IMO this is a particularly bad time to sequester oneself from information voluntarily

😬 @mikefeigin.bsky.social

Mad at you @mikefeigin.bsky.social for making me come here to tell you I’m stoked for our annual matchup

The "bioRxiv should check methods" issue came up frequently on twitter. See thread in which @pracheeac.bsky.social @michaelhoffman.bsky.social and I explain the complexity x.com/cshperspecti... which I'll summarizeagain _here_ for those who don't want to go _there_ 1/n

Surprising absolutely nobody is that the conversation with @pracheeac.bsky.social was also one of my faves - as every conversation I get to have with Prachee is. pod.fo/e/12a435 (you might want to listen at a slower speed 😀)

Nailed it

Some distinctly cool shit going on over at @arcadiascience.com via @pracheeac.bsky.social et al., research.arcadiascience.com/pub/perspect... Favorite part by far is documenting mistakes/errors/things that didn't work so well (yeah I am 7 months late to this)

Some of the best ways to take advantage of preprints: share broadly that you posted one but also to send your preprint directly to colleagues who might care and may have missed it. Just as you like to be alerted to research you care about and may not have seen yet, so does everyone else

An example of how the limited and biased availability of data narrows the range of functional biology PLMs tap into for prediction and design research.arcadiascience.com/pub/result-p...

#PubDrop! We've been experimenting with a more scientist-led approach to open publishing at @arcadiascience.com. After 6 months, here's what we've learned about putting researchers fully in charge of sharing their work… 🧵 1/8 research.arcadiascience.com/pub/result-e... 🧪#ScientificPublishing