Introducing AutoOpenRaman, an automated, inexpensive microscope setup for Raman spectroscopy! We recapitulated many features of expensive commercial systems using economical hardware and open-source software 🧵 [1/8] research.arcadiascience.com/pub/resource...

Chlamydomonas cpc1-1 mutant exhibits unexpected growth phenotypes

After many yrs building internally @arcadiascience.com we're now able to partner more with others on cool organisms. You won't hurt my feelings if you don't read my post, but don't miss out on our first organismal spotlight animation featuring sea squirts -- just skip to the bottom! 🧵

Our blog is now on Substack! Check out our first post there, which includes a fun video we made about why you might want to study sea squirts open.substack.com/pub/arcadias...

AI laboratory for lit review

New website who dis www.arcadiascience.com

Want to give input to help your fellow scientists? We’ve updated our list of preprints in need of feedback: bit.ly/preprintrequests We’re having our own preprint commenting event next Friday. We’ll consider reading your work if you add it to the list: bit.ly/submitpreprint

Two Arcadia talks today! 11:15 am — Athena CD — George Sandler “The potential of machine learning for genomic prediction in a quantitative genetics framework” 11:45 am — Athena F — Ryan York “Evolution determines what machines can learn”

Calling all scientists! 🚨 Share feedback on preprints that need it! Check out our updated list: bit.ly/preprintrequests We’re hosting our next internal preprint commenting party this Friday, and might review your work! Submit it here: bit.ly/submitpreprint

As #Evol2025 talks wrap up for the day, our mixer begins! Come upstairs at The Globe any time til 7:30 to learn about opportunities at Arcadia over charcuterie & drinks 🍷🧀 We’re looking for a Computational Evolutionary Biologist, Evolutionary Cell Biologist, and more…

📢 Hey #Evol2025 attendees, we’re hiring! If you’re interested in #careers at Arcadia, swing by our free mixer upstairs at The Globe today from 5:30 to 7:30. It’s a 7-minute walk from the Classic Center and drinks are free 🍻 jobs.lever.co/arcadiascience

First Arcadia talk at @evolmtg.bsky.social‬! #Evol2025 Today — 3 pm — Athena CD Austin Patton presents “Graph neural networks: A unifying predictive model architecture for evolutionary applications”

We’re at ‪@evolmtg.bsky.social‬! Follow us for updates on talks as the conference unfolds. We’re also hosting a free careers mixer 🍺 at The Globe tomorrow @ 5:30 pm — join us! #Evol2025

#PubDrop bsky.app/profile/cdma...

>march 10 @arcadiascience.com announces new form of rapid publishing >apr 18 team reads a preprint, finds it interesting >9 work days later, team publishes results validating and extending model this is how science should be. open, rapid, with the community arcadia-science.github.io/2025-geno-ph...

Not only do we do cool science but we have a badass illustrator for our pubs

One of our scientists whipped up a lit review terminal program where AI agents with different expertise collaboratively discuss #biorxiv and #arxiv preprints 🤖🧪📚 github.com/Arcadia-Scie... Anyone here using an agent-based research tool you recommend?

Help advance science by giving feedback! #SharingIsCaring Browse our list of preprints that need feedback: bit.ly/preprintrequests We’re hosting a #preprint commenting event this Friday — submit your work for consideration: bit.ly/submitpreprint

Early update on Arcadia publishing 2.0: Scientists are in charge, speed is an issue

Rescuing Chlamydomonas Motility in Mutants Modeling Spermatogenic Failure

Researchers often use a compound called 48/80 to activate mast cells for degranulation assays... But it's toxic ☠️ in the two cell lines we tested: HMC1.2 (human mast cells) and RBL-2H3 (rat basophils) This could confound many studies — please share! 🧪 research.arcadiascience.com/pub/result-4...

We're trying a new publication format — the notebook pub! By turning our Jupyter Notebooks into publishable artifacts, we hope to share faster, reduce the effort to convert analysis ➡️ pub, and make our work more reproducible. Weigh in on our commentary: research.arcadiascience.com/pub/perspect...

Scientists: Share your expertise with your peers! #GiveFeedback Check out our updated list of preprints seeking valuable input: bit.ly/preprintrequests Have a preprint that needs feedback? Add it to our list: bit.ly/submitpreprint

Happy Darwin Day! Today, we’re thinking about how to use evolution to accelerate biomedical research. We think the answer is to expand the repertoire of organismal models. Search for the best ones using our new portal, Zoogle: zoogle.arcadiascience.com 🧵

New job @arcadiascience.com! Ideally you've got a few years of experience post-PhD, in academia or elsewhere, and have some computational fluency in addition to experimental expertise. Added bonus, you'd get to join our pastry-fueled preprint comment parties like the one we're having today :)

When choosing a model organism, scientists often focus on a handful of species. But the tree of life offers much more, so how can we leverage it? Scientists @arcadiascience.com mapped 1 billion+ years of evolution and developed a rational approach anyone can use: doi.org/10.57844/arc...

Want to support fellow researchers in the new year? Check out the latest preprints seeking feedback 👉 bit.ly/preprintrequests Or add your work to the list 👉 bit.ly/submitpreprint

Today at #CellBio24, I'll discuss our new pub at the "Quantitative Biology in Emerging Model Systems" subgroup session at 5:15 pm in Ballroom 20A. Come check it out!

Today at #CellBio24, Dave Mets will be at poster B599 talking about mapping genotypes to phenotypes! poster: zenodo.org/records/1449...

We 🖤 #OpenRAMAN!

🧵 New from @arcadiascience.bsky.social: We used Chlamydomonas mutants to model specific types of spermatogenic failure and found drugs can rescue swimming behavior in mutation-specific ways. Full pub: research.arcadiascience.com/pub/result-chlamy-spgf [1/8]

I even have some @arcadiascience.bsky.social stickers and organism temp tattoos. Come find me after my talk if you want one! #cellbio2024

Come find us at #CellBio24! Our CSO @pracheeac.bsky.social is giving a talk today, and then we've got another talk and a bunch of posters during the rest of the conference. Come say hey!

Help advance science by giving feedback! #SharingIsCaring Browse our list of preprints that need feedback: bit.ly/preprintrequests We’re hosting a preprint commenting event this Friday — submit your work for consideration: bit.ly/submitpreprint

We curate a list of biology-focused preprints for which authors have requested comments: bit.ly/preprintrequests We pull @prereview.bsky.social requests, preprints ppl have requested feedback for on X/Bluesky, and sometimes our own work from PubPub. Add yours! bit.ly/submitpreprint 🧪🧬 🖥️ #evobio

Let's give this a go on bsky...WE'RE HIRING! We have multiple really cool positions I'd love to see some creative and passionate people apply to (all PhDs): - Protein Designer - Protein Biochemist - Talent Recruiter #chemsky #bluesci #AIsky @arcadiascience.bsky.social jobs.lever.co/arcadiascience

🧵 [1/6] Have you ever wanted to study single-cell motility but don’t have a workflow that can capture and analyze fast swimming dynamics in high throughput? We did, so we developed a microscopy workflow and analysis pipeline, SwimTracker research.arcadiascience.com/pub/resource...

💬 New preprint evaluation by @arcadiascience.bsky.social of A Structural Proteome Screen Identifies Protein Mimicry in Host-Microbe Systems https://sciety.org/articles/activity/10.1101/2024.04.10.588793?utm_source=bluesky&utm_medium=social&utm_campaign=preprint_review #PreprintEvaluation

Hey new followers hey You can see all our recent work on our publishing site: research.arcadiascience.com We'll be adding a lot of science before the end of the year, but check out our latest on tracking single-cell motility, finding circular DNA in seq data, and more Public comments encouraged!

Interested in commenting on 🧪 preprints but unsure of how to get started? Check out our how-to guide so you can contribute to the open science community ASAP! 👉 arcadia-web-assets.s3.us-west-1.amazonaws.com/publishing/a...

1 more week before we dig into EA apps @ArcadiaScience. Know someone unapologetically TypeA who wants front row seats to building a new science org/biotech start-up? I hope they quickly grow into Chief of Staff. I value drive/generalist competence >>> experience/polish. jobs.lever.co/arcadiascien...

Two weeks ago we @arcadiascience.bsky.social posted our final, major update to our Chlamydomonas sp. phenotypic variation pub! research.arcadiascience.com/pub/result-c...! A lot of new findings in the 🧵!!! 1/9

We’re at #cellbio2023! Visit us at booth #434 or check out ascb2023.arcadiascience.com to see posters we’re presenting and more!

🎉 Excited to share our latest work at #CellBio23! I'll be presenting a poster on our pub “Phenotypic differences between interfertile Chlamydomonas species” and our continued work in the Protists and Parasites Cell Biology poster session (Board #723) @arcadiascience.bsky.social