Cameron Dale MacQuarrie
@cdmacquarrie.bsky.social
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📥 614
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Scientist at Arcadia Science Berkeley, CA, USA Cell Biology He/Him
Discovered some unexpected growth phenotypes in Chlamydomonas flagellar mutants! The cpc1-1 strain (with central pair complex defects) shows surprising metabolic traits that might be independent of its flagellar defects. 🧵
research.arcadiascience.com/pub/observat...
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Chlamydomonas cpc1-1 mutant exhibits unexpected growth phenotypes
Comparative analysis of <i>Chlamydomonas </i>strains revealed that a <i>cpc1-1</i> mutant has three unexpected growth phenotypes across different media types, suggesting possible genetic background co...
https://research.arcadiascience.com/pub/observation-chlamy-cpc1-growth
4 months ago
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reposted by
Cameron Dale MacQuarrie
Arcadia Science
8 months ago
Happy Darwin Day! Today, we’re thinking about how to use evolution to accelerate biomedical research. We think the answer is to expand the repertoire of organismal models. Search for the best ones using our new portal, Zoogle:
zoogle.arcadiascience.com
🧵
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Today at
#CellBio24
, I'll discuss our new pub at the "Quantitative Biology in Emerging Model Systems" subgroup session at 5:15 pm in Ballroom 20A. Come check it out!
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10 months ago
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Today at
#CellBio24
, Dave Mets will be at poster B599 talking about mapping genotypes to phenotypes! poster:
zenodo.org/records/1449...
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10 months ago
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Our new pub dropped this weekend! For those at
#CellBio24
, I'll be at poster B73 starting at 11:15 am discussing this work! I'll also be giving a talk on Tuesday at 5:15 pm in Ballroom 20A in the Quantitative Biology in Emerging Model Systems session poster here:
zenodo.org/records/14481493
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10 months ago
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🧵 New from
@arcadiascience.bsky.social
: We used Chlamydomonas mutants to model specific types of spermatogenic failure and found drugs can rescue swimming behavior in mutation-specific ways. Full pub:
research.arcadiascience.com/pub/result-chlamy-spgf
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Rescuing Chlamydomonas motility in mutants modeling spermatogenic failure
We used Chlamydomonas reinhardtii motility mutants with disrupted genes homologous to human SPEF2 or DNALI1 to model spermatogenic failure disorders SPGF43 and SPGF83, respectively. We recovered aspec...
https://research.arcadiascience.com/pub/result-chlamy-spgf
10 months ago
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Tomorrow at
#CellBio24
, I'll be at poster (B73) talking about some fun new work we just released using Chlamydomonas to model spermatogenic failure. Check out the poster here:
zenodo.org/records/14481493
Join the fun and post your comments & questions on the pub!
bit.ly/chlamy-spgf
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10 months ago
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Happening soon at
#CellBio24
@ascbiology.bsky.social
Ryan York's poster (B574) on a data-driven approach to selecting your model organism
@arcadiascience.bsky.social
Poster here:
zenodo.org/records/14479386
Join the fun & post your comments & questions on the pub!
bit.ly/evolutionary...
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10 months ago
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reposted by
Cameron Dale MacQuarrie
Prachee Avasthi
10 months ago
Ryan’s poster:
zenodo.org/doi/10.5281/...
The concept:
research.arcadiascience.com/pub/idea-sel...
The approach and analyses:
research.arcadiascience.com/pub/result-e...
The validation:
research.arcadiascience.com/pub/result-c...
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reposted by
Cameron Dale MacQuarrie
Prachee Avasthi
10 months ago
If you’re at
#CellBio2024
drop by Ryan’s poster today (Board B574) to hear the latest from
@arcadiascience.bsky.social
about how you can choose the right model system for your research or find areas best studied in the species you have expertise/infrastructure Poster and publications below
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reposted by
Cameron Dale MacQuarrie
Joseph W. Brown
12 months ago
Annual reminder that PhyloPic is your free go-to source for organismal silhouettes for
#Jack-o'-lantern
designs
phylopic.org
@tmkeesey.bsky.social
🧪
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PhyloPic
PhyloPic is an open database of free silhouette images of animals, plants, and other life forms, available for reuse under Creative Commons licenses. Download silhouettes for use in educational materi...
http://phylopic.org
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Two weeks ago we
@arcadiascience.bsky.social
posted our final, major update to our Chlamydomonas sp. phenotypic variation pub!
research.arcadiascience.com/pub/result-c...
! A lot of new findings in the 🧵!!! 1/9
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Phenotypic differences between interfertile Chlamydomonas species · Genetics: Decoding evolutionary...
We’re crossing C. reinhardtii and C. smithii algae for high-throughput genotype-phenotype mapping. In preparation, we’re comparing the parents to uncover unique species-specific phenotypes.
https://research.arcadiascience.com/pub/result-chlamydomonas-phenotypes
almost 2 years ago
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🎉 Excited to share our latest work at
#CellBio23
! I'll be presenting a poster on our pub “Phenotypic differences between interfertile Chlamydomonas species” and our continued work in the Protists and Parasites Cell Biology poster session (Board #723)
@arcadiascience.bsky.social
almost 2 years ago
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DALL-E's take on a colored pencil sketch of Chlamydomonas
almost 2 years ago
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🚨
@arcadiascience.bsky.social
is hiring an Image Analysis scientist!!! 🔬
jobs.lever.co/arcadiascien...
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Arcadia Science - Scientist, Image Analysis
A Bit About Us: We are Arcadia Science. Arcadia is a science company founded and led by scientists. Our mission is to transform evolutionary innovations into real-world solutions by openly developing ...
https://jobs.lever.co/arcadiascience/14d3bed3-be02-47eb-ac4c-fa730180073f
about 2 years ago
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Are you a Chlamydomonas reinhardtii or Chlamydomonas smithii? Find out here!!!
www.buzzfeed.com/cameronmacqu...
#SpiritAlgae And check out the latest version of our
@arcadiascience.bsky.social
pub comparing the 2 species!
research.arcadiascience.com/pub/result-c...
#ArcadiaGenetics
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Are You Chlamydomonas Reinhardtii Or Chlamydomonas Smithii?
Which microalgal species are you? Read the pub here: https://research.arcadiascience.com/pub/result-chlamydomonas-phenotypes/
https://www.buzzfeed.com/cameronmacquarrie/which-chlamydomonas-species-are-you-g7825nudn4
about 2 years ago
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reposted by
Cameron Dale MacQuarrie
Arcadia Science
about 2 years ago
🗣️ Calling all microscopy enthusiasts! We're looking for publicly available, open-source video data featuring bright-field, DIC, or phase-contrast images. These data will complement our own in a new study on focus-filtering techniques. Please comment with a link to a public repository!
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New pub update from
@arcadiascience.bsky.social
! ! We've just released an update to our research on the 2D cell morphology of C. reinhardtii and C. smithii, two interfertile algal species.
research.arcadiascience.com/pub/result-c...
about 2 years ago
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