MD simulations show that diffuse scattering patterns shift depending on whether ligand or a buffer molecule occupies the binding pocket. The differences are quantitatively significant, a promising sign that experiments could detect these changes. Read more: diffuse.science/post/shake-i...

Tomorrow (2/27) 3 pm ET, DiffUSE Project Scientist Steve Meisburger presents "Diffuse Scattering Wars (Episode IV): A New Hope for Structural Biology" Learn how diffuse scattering could reveal what AI structure predictors are missing. Join here: www.chess.cornell.edu/science/ches...

@andolab.bsky.social undergrads at the beamline! Here are Marcus, Katie, Sarah, and Shaheer collecting data for @diffuseproject.bsky.social with @meisborg.bsky.social and @xiaokunpei.bsky.social 😎💥

I spend a lot of time talking to potential grantees about our open science policy. Some field notes here: open.substack.com/pub/seemay/p...

The Diffuse Project is looking for an amazing Project Manager to help us achieve our goal of unlocking protein dynamics! Are you a scientist who naturally loves organization, coordination, problem solving and working with a diverse team of scientists & engineers?