Michael Skinnider
@skinnider.bsky.social
📤 1317
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assistant professor at Princeton University interested in biological and chemical data
reposted by
Michael Skinnider
Science Magazine
3 months ago
Comparative whole-brain and single-cell analyses are identifying neurons orchestrating neurological functions. Learn more in a new
#SciencePerspective
:
https://scim.ag/3JOh0co
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Unbiased discovery of neuronal architectures
Comparative whole-brain and single-cell analyses identify neurons orchestrating neurological functions
https://scim.ag/3JOh0co
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Thrilled to share our approach for language model-guided discovery of unknown mammalian metabolites: DeepMet. We’ve now used this approach to discover ~50 new human and mouse metabolites!
www.biorxiv.org/content/10.1...
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Language model-guided anticipation and discovery of unknown metabolites
Despite decades of study, large parts of the mammalian metabolome remain unexplored. Mass spectrometry-based metabolomics routinely detects thousands of small molecule-associated peaks within human ti...
https://www.biorxiv.org/content/10.1101/2024.11.13.623458v1
about 1 year ago
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Very happy to share this work testing a widespread assumption in chemical AI and showing that invalid SMILES are a feature, not a bug:
www.nature.com/articles/s42...
almost 2 years ago
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Very happy to share our latest work on harmonizing raw mass spectrometry data from >21,000 proteomic experiments to enable meta-analyses of protein interactions and phosphorylation at the largest scale yet:
www.nature.com/articles/s41...
about 2 years ago
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