Now published, our tool to run (almost) all biological models interactively in your web browser Paper: academic.oup.com/bioinformati... Website: biomodels.bacpop.org Code: github.com/bacpop/SBMLt...

Finally out! Thrilled to share our collaboration with @kulathu.bsky.social, @orafurman.bsky.social, and N Davey. We screened auxiliary domains of USP family #deubiquitinases, revealing short linear motifs (SLiMs), contributing to specificity in complex assembly. www.biorxiv.org/content/10.1...

Join us for this exciting meeting!

Francesco will be speaking at the High-Content CRISPR Screening conference, taking place March 18–19, 2026 in Vienna 🇦🇹 alongside leading experts in CRISPR screening, functional genomics, and drug discovery www.linkedin.com/posts/myllia...

For additional open calls for leadership roles at EMBL, also check out: embl.wd103.myworkdayjobs.com/EMBL We’re looking for: Hamburg: Group Leader Grenoble: Group Leader Heidelberg: Two Group Leaders, Team Leader, Unit Head

Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer

🚨 New in PNAS! 🧬 64% of disease co-occurrences can be explained by transcriptomic similarities. Comorbidities aren’t random—they have a molecular basis. Here’s how we found it 👇 (1/n) 🔗 doi.org/10.1073/pnas.2421060122 @alfonsovalencia.bsky.social

📢 Recruitment for the EMBL International PhD Programme is officially open! At EMBL, we train young scientists to become skilled and creative future leaders in academia and other sectors. Join us and get a head start on your career in life sciences! bit.ly/47mmiFF

'The Computation & Theory research area at Janelia seeks exceptional Group Leaders to advance our understanding of complex biological systems through theory, computational modeling, multi-modal data integration, and interpretable machine learning.' #ScienceJobs www.janelia.org/content/lead...

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

Monumental effort from @maxbillmann.bsky.social and colleagues, quantifying genetic interactions among 4 million human gene pairs. Lots of features associated with genetic interaction & GI degree conserved from yeast. www.biorxiv.org/content/10.1...

Very happy to have collaborated with Yifei and Jaime in these exciting projects!

Thrilled to collaborate with Mathew Garnett @Sanger and Parse Biosciences on the new Cancer Plasticity Atlas – a hugely exciting single cell genomics resource to decode tumor adaptation. 🔗 helmholtz-munich.de/en/newsroom/news-all/artikel/cancer-plasticity-atlas-to-improve-cancer-therapies

Deadline this Sunday!

Having held this position for almost three years, I can say it’s a super friendly and fun committee to be involved in! Reach out if you have any questions 🙂

🚨 Most variant screens measure growth or abundance. What do they miss? That variants impact a spectrum of protein and cellular phenotypes. Variant in situ sequencing (VIS-seq) finds what’s missing: image cells 🔬 first, decode later, revealing multi-scale phenotypes for thousands of variants.👇 1/9

Our first plenary session starts with @slavov-n.bsky.social telling us about single cell proteomics and moving it to biological function

We're recruiting junior team leaders @mrc-lms.bsky.social This time we're looking for those working in human metabolic disease. It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us! lms.mrc.ac.uk/work/vacanci...

Deadline coming up! Post doc on making Digital Twins for rare disease, collaboration with Ellie McDonagh @opentargets.org and Rahuman Sheriff @biomodels.bsky.social @ebi.embl.org funded by @cziscience.bsky.social

NEW: Postdoc with @saezlab.bsky.social Develop integrative computational pipelines to dissect immune-cell phenotypes and cell–cell interactions across Alzheimer’s, Parkinson’s, and ALS patient tissues Closes 20 July #postdocJobs #neuroskyence embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

We're extremely grateful to Wellcome @wellcometrust.bsky.social for engaging in a more long-term funding collaboration with EMBL-EBI. This will enable us to continue developing our open data resources for global users & leverage innovation in new areas such as AI 🌍 www.ebi.ac.uk/about/news/a...

Variant characterization in the intrinsically disordered human proteome - here is how we did it using short linear motif prediction, AlphaFold, and experimentation. Check out our preprint: www.biorxiv.org/cgi/content/...

Do you have experience in mechanistic modelling of biological systems and want to do a postdoc with an interdisciplinary team on developing Digital Twins for rare disease? We have the job for you! Check it out below - deadline July 13th, online interviews 24th July.

We are looking for a PhD student in (mostly )wet-lab biochemistry to work on short linear motifs, intrinsically disordered regions, in the context of the Marie Curie network "IDPro". More info an apply here: www.uu.se/en/about-uu/...

The final version of our multi-omics study on kidney fibrosis is out now (tinyurl.com/kidneyfibMSB). Together w/ Pepperkok + Savitski labs @embl.org, we present a time-resolved #multiomics + computational network modeling approach in combination w/ phenotypic assays to study #kidneyfibrosis

The Karolinska Institute announces 20 positions for Assistant Professors for outstanding early-career researchers. Positions include a startup package. Application deadline September 2nd. ki.varbi.com/en/what:job/...

🚨Awesome comms jobs alert! The @ebi.embl.org Comms team is looking for two new colleagues: 🟢 Deputy Head of EMBL-EBI Communications 🟢 Communications Officer Applications close on 20 July. One of them is my role which I'm finishing in a few months after 9 incredible years. Why apply?

Your weekly reminder that there is a really fun post @ebi.embl.org in our group in collaboration with Sheriff Rahuman (@biomodels) and Ellie McDonagh (@opentargets) to create Digital Twins for rare disease using multiomics, executable modelling and AI. Join our interdisciplinary team! Deadline 13/07

Today’s Impromptu Seminar at CeMM featured @epetsalaki.bsky.social (@ebi.embl.org‬), who shared her lab’s work on context-specific signalling using network modelling & machine learning. From melanoma resistance to MASLD, a fascinating session—thank you, Evangelia & @ar-abdelfattah.bsky.social!

It is such a pleasure being at CeMM, what great discussions!

Exciting opportunity at the forefront of network biology, multiomics, AI and DT. Deadline 13th July! embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

I, Rahuman Sheriff @biomodels.bsky.social and Ellie McDonagh from @opentargets.org @ebi.embl.org are looking for an enthusiastic postdoc with skills in executable modelling to create Digital Twins for rare disease (CZI-funded project).

In our most recent paper, we uncover the myelin-axon interactome in human brains and reveal molecular perturbations and structural disruptions at the myelin-axon interface in Alzheimer’s disease @jgrutzendler.bsky.social @epetsalaki.bsky.social @reimand.bsky.social www.nature.com/articles/s41...

I, Rahuman Sheriff @biomodels.bsky.social and Ellie McDonagh from @opentargets.org @ebi.embl.org are looking for an enthusiastic postdoc with skills in executable modelling to create Digital Twins for rare disease (CZI-funded project).

Delighted that the 'flagship' manuscript on our @genesandhealth.bsky.social 44k exomes (British Pakistanis & Bangladeshis) is now preprinted. Great academic-industry collaboration. Lots of new associations (mostly additive, a few recessive) and new insights into homoz knockouts & drug discovery.

2 weeks left to apply for our new fully funded postdoc position studying plasticity regulators in metastatic CRC!

We are looking for a postdoctoral fellow to come work with us: www.cruk.manchester.ac.uk/career/mi-25... Please reach out

We are recruiting two exciting #Postdoctoral roles: 🧪 Work with @clausjorgensen.bsky.social on targeting the tumour #microenvironment in #PancreaticCancer 🥼 Join @drwilliamhill.bsky.social to study air pollution & #LungCancer Full details of both positions at: www.cruk.manchester.ac.uk/careers/

As a reminder there is one week left to register for the BSPR 2025 Annual Conference. Make sure you dont miss out!

Great opportunity for early-career students. We also offer an internship project at the intersection of machine learning and healthcare - exploring privacy risks in pre-trained AI models.

Update of our protein outlier caller PROTRIDER. We now handle missing values, a widespread issue for mass spec where missing values are not a random -- and this improves outlier detection on non-missing data! Thumbs up to Daniela and George for the great work. doi.org/10.1101/2025...

KODAMA goes spatial. doi.org/10.1101/2025... #spatialtranscriptomics #visium #visiumhd #seurat #giotto

Long-read sequencing can reveal hidden cancer mutations, but existing tools often produce false positives. SAVANA is a machine learning algorithm trained on cancer genomes, built to make analysis faster and clinically reliable. @isidrolauscher.bsky.social www.ebi.ac.uk/about/news/r... #oncosky

Ever wondered which method to use to infer kinase activities from phosphoproteomics data? 💻💭Our revised comprehensive evaluation of kinase activity inference tools, done in collaboration with the Zhang lab @bcmhouston.bsky.social, is now out @natcomms.nature.com 🔬 tinyurl.com/4twuc6z4

Excited to share our new preprint showcasing a method to infer transparent, mechanistic network models of biological pathways using graph neural networks! www.biorxiv.org/content/10.1...

We are recruiting! We're searching for a postdoctoral research fellow to study patient-specific regulators of plasticity in primary and metastatic CRC. Please reach out if you have any questions! www.ucl.ac.uk/work-at-ucl/...

🏎️⬅️🔥 bme.ubc.ca/back-to-the-...

Very excited that another chapter of my PhD is finally out! 🎉 We compared methods to infer kinase activities from #phosphoproteomics data so check it out if that sounds interesting to you. More details in the thread below 🧵👇🏼

I am excited to begin my new journey as the Head of Cellular Genomics @sangerinstitute.bsky.social We will decode and recode tissue ecosystems using AI + big data… Our amazing faculty include Roser Vento-Tormo, @bayraktarlab.bsky.social, Mo Lotfollahi, Sam Behjati and Song Chen..

Happy to share details of this meeting and the exciting line-up of speakers. Hope to see you there. Please re-post www.crick.ac.uk/whats-on/5th...