Which human brain circuits are implicated in neurodevelopmental conditions? We bridged human genetics, spatial transcriptomics and neurodevelopment to discover the convergence of autism-associated genes in the developing human thalamus! www.biorxiv.org/content/10.1...

NEW: Technical specialist with @bayraktarlab.bsky.social Generate large-scale spatial transcriptomic datasets to create comparative cell atlases of ALS, Alzheimer’s disease and Parkinson’s disease #scienceJobs #neuroskyence sanger.wd103.myworkdayjobs.com/en-US/Wellco...

NEW: Postdoc in neurodegenerative disease spatial transcriptomics and ML with @bayraktarlab.bsky.social/Mo Lotfollahi Join a new project to create comparative cell atlases of ALS, Alzheimer’s disease and Parkinson’s disease #postdocJobs #neuroskyence sanger.wd103.myworkdayjobs.com/en-US/Wellco...

📢 @bayraktarlab.bsky.social & colabs at @sangerinstitute.bsky.social are assembling the @opentargets.org funded Neuroimmune Team 🧠🧬-Leverage AI to uncover neurodegeneration Tech Spec: sanger.wd103.myworkdayjobs.com/en-US/Wellco... Postdoc AI: sanger.wd103.myworkdayjobs.com/en-US/Wellco...

Very excited about our new chapter with @mhaniffa.bsky.social !

Two massive glioblastoma papers, datasets, trajectories, insights, and.. a very cool new method for GRN inference - scDORI -from @steglelab.bsky.social @oliverstegle.bsky.social @bayraktarlab.bsky.social & Moritz Mall www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵