Cancer Research UK is fed up of paying too much for open access publishing so they are completely stopping funding this activity: news.cancerresearchuk.org/2026/04/01/w...

New opportunity with the Vienna BioCenter Scientific Training Team! 🙌 As PhD Program Manager, you’ll play a key role in empowering and shaping the careers of the next generation of world-class researchers ➡️ tinyurl.com/yrk23na2

New preprint! We identified many components that localize to the structure involved in "eating" in a marine organism. #ProtistOnSky #diplonemid www.biorxiv.org/content/10.6...

Monthly median Received to Accepted time (days) at Nature Genetics

Check out our first lab preprint: A real team effort to understand the Plasmodium GAPM proteins, which form part of a essential bridge between the parasite's cytoskeleton and motility apparatus. Below is a sneak peek of some beautiful microscopy - light and electron! www.biorxiv.org/content/10.6...

Excited to share my postdoc work on the cryo‑EM structure of the budding yeast telomerase holoenzyme! 🧫🧬 It’s been a real privilege to be part of the awesome Kelly Lab @kellythd-nguyen.bsky.social. Grateful as well to the incredible facilities @mrclmb.ac.uk.

Have a look at our latest results on #CDK regulation, just posted as a pre-print! This study was spearheaded by PhD student Amy McGeoch. Amy has determined the #cryoEM structure of the CDK11-cyclin L-SAP30B complex, an important regulator of #spliceosome activation. www.biorxiv.org/content/10.6...

Microtubules guide Aurora B substrate geometries for accurate chromosome segregation pubmed.ncbi.nlm.nih.gov/41880487/ #cryoem

Happy to share my first adventure in #TeamTomo in collaboration with the talented @inaharasimov.bsky.social. It was a fun experience experience with a lot of learning along the way.

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

Fun collaboration with the Herzik lab! Very cool to see #TeamTomo + STA directly capture the effects of the AWI at the single-particle level. we know it’s happening, but it’s striking to see it so clearly!

‼️Paclitaxel, the best-selling chemotherapy drug in history, may not act exactly as previously thought. It can profoundly alter nuclear morphogenesis during interphase, thereby disrupting critical cellular processes through perturbation of the nuclear domain. doi.org/10.1242/jcs....

Happy to see the first paper from the lab published in the EMBO J today: link.springer.com/article/10.1... In it, we reconstitute self-assembling cooperative oligomers of human Ndc80 and Ska kinetochore complexes that stabilise microtubule ends, and study these samples using cryoET and TIRF

You can download RELION-5.1 from github.com/3dem/relion (branch ver5.1) Note that the beautiful startup image of dynein:dynactin on a microtubule was provided by Sami Chabaan from the @carter-lab.bsky.social. 🤗

We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo. #OpenSoftwareAcceleratesScience

AlphaFold database has entered the era of complexes. Together with NVIDIA, DeepMind and EBI, we use ColabFold, OpenFold and MMseqs2-GPU to predict ~31 million complexes (homo & hetro-dimers) resulting in 1.8 million high-quality predictions 📄 research.nvidia.com/labs/dbr/ass... 🌐 alphafold.ebi.ac.uk

New OpenFold3 preview out! (OF3p2) It closes the gap to AlphaFold3 for most modalities. Most critically, we're releasing everything, including training sets & configs, making OF3p2 the only current AF3-based model that is functionally trainable & reproducible from scratch🧵1/9

Exciting job opportunity in lovely Bern working in the Gluenz lab @izb-unibern.bsky.social ohws.prospective.ch/public/v1/jobads/e8d8d00d-ecc8-44b3-9ec5-1b9799e66080

Holy smoke. What ultimately happened???

www.biorxiv.org/content/10.6... Amazing work by Kris and gang! For the first time we have been able to image division ring components live in Sulfolobus. And guess what - CdvA is asymmetrically inherited.

I’m very excited to share some newly published work that uncovers the molecular basis for oligomannose synthesis! www.nature.com/articles/s41...

Very excited to share our latest preprint, where we visualize the impact of force on the catch bonding actin crosslinker α-actinin-4. Led by @tri-i.bsky.social MD-PhD student Alfred Chin, a great collaboration with Glen Hocky's lab. www.biorxiv.org/content/10.6...

In vitro reconstitution is powerful: we can rebuild Plasmodium microtubule architectures from purified components and recapitulate what cells actually do 🤩 Thanks to an incredible team that made this possible 🙌 @carolynmoores1.bsky.social in particular rdcu.be/e7eM2

We have started a project trying to predic the interactions/structures of all yeast protein pairs using an AlphaFold pooling approach. We are making the current dataset open and we welcome collaborations. www.evocellnet.com/2026/03/mapp...

We made a tool for generating seam-corrected microtubule reconstructions using CryoSPARC - please check it out! www.biorxiv.org/content/10.6...

👋 To all aneuploidy and chromosome instability aficionados check out the Consequences of Aneuploidy FASEB conference (Florida-USA 🏖️) co-organised with @peterlylab.bsky.social, Mike Lampson, Alison Taylor and myself: events.faseb.org/event/Aneupl... 👉 Deadline for abstract submission: August 3rd.

Excited to share our new preprint exploring how Paramecium achieves diverse flow functions, i.e. feeding and swimming, simultaneously. This work was spearheaded by our ExM expert, PhD student Daphne Laan @daphnelaan.bsky.social : www.biorxiv.org/content/10.6...

Reminder: the entire NSF budget is 9B and NIH like 47B. And they have 500B that they don’t know how to spend.

Our latest preprint: Together with the team of Jan Löwe, @danieltamarit.bsky.social and many others we discovered and characterized several Asgard tubulin genes and propose that microtubule architecture and dynamics evolved in Asgard archaea prior to eukaryogenesis www.biorxiv.org/content/10.6...

We have an open Assistant Professor position (tenure track) @ethz.ch in Computational Immunology - ethz.ch/en/the-eth-z... Please apply / share!

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in @science.org on a new small polymerase. 1/n

Anybody know what the threshold was for MSCA funding this time round? Results are coming out and it looks brutal.

Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

We're launching a research lab at SMART. Shenzhen Medical Academy for Research and Translation is a newly established institute with long-term funding mechanisms for internal and external investigators. At full capacity SMART aims to support up to 400 labs. www.scmp.com/news/china/s...

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

The origin of eukaryotic cells continues to be one of the greatest mysteries in biology. EMBL Grenoble is excited to welcome Florian Wollweber, who will use cutting-edge imaging techniques to study Asgard archaea — microbes closely related to our earliest ancestors. 🦠🔬 www.embl.org/news/people-...

🚨Postdoc opportunity🚨Our lab at MRC-LMB Cambridge is recruting a postdoc to study transcription-coupled splicing using cryoEM and endogenous isolation! 🔬 🧬 Please feel free to get in touch directly #postdoc #cryoEM #biochemistry #splicing Apply here by 11 Feb www.nature.com/naturecareer...

So excited to share the preprint with the bulk of my PhD work in the Beach @myosincity.bsky.social and Oakes @pwoakes.bsky.social Labs at Loyola University Chicago! We investigate the structure, recruitment, and function of septin networks around the nucleus. A thread: doi.org/10.64898/202...

📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere. 🔗 Apply here 👉 recruitment.crg.eu/content/jobs...

🔬 Postdoc position – Infection Biology & Cryo-ET (Zurich) 🇨🇭 We are looking for a motivated Postdoc to join our interdisciplinary team. 📩 Interested? Check out the job advert: www.imm.uzh.ch/dam/jcr:cb17... 👉 More info on the lab: www.weiss-laboratory.com Please share with interested colleagues!

The EMBO Workshop "#Centrosomes: From fundamentals to diseases" in #Lausanne, Switzerland, 1–4 September 2026 will highlight the advances in the field of centrosome #research. Register now! Deadline: 1 June https://meetings.embo.org/event/26-centrosomes#Centrosomes#Lausanne#research#EMBOCentrosomes #EMBOevents #conference 🧪

🧬🔬@science.org A genetically encoded device for #transcriptome storage in mammalian cells | Science www.science.org/doi/10.1126/... @broadinstitute.org

We are hiring a postdoctoral researcher to investigate ribosome hibernation and activation in microsporidia using confocal microscopy, soft X-ray tomography, cryo-electron tomography, and omics approaches. If you are interested, apply here: jobs.exeter.ac.uk/hrpr_webrecr...

New preprint from the lab 🎉: γ-tubulin is a novel target of the tubulin autoregulation pathway! Previously thought to exclusively target α- and β-tubulin mRNAs, we show that the TTC5–SCAPER–CNOT11 axis also degrades γ-tubulin mRNA, expanding the scope of this fundamental regulatory mechanism.

Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

We’re excited to announce the opening of the Geneva Expansion Microscopy Facility (GenExM)! GenExM is a full-service U-ExM platform (U-ExM, Cryo-ExM, iU-ExM), delivering nanoscale imaging. Led by Dr. Olivier Mercey, GenExM welcomes academic & industrial collaborations. 👉 www.unige.ch/genexm/

🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.

Congrats to Michal Wieczorek (wieczorekgroup.ethz.ch/research.html, IMBB) on being selected as an @embo.org Young Investigator. The 2024 cohort highlights excellence across the life sciences, and this recognition reflects Michal’s outstanding scientific contributions.

Mike has been selected as EMBO YIP! Huge congrats to Mike and his team! 🥳 @mike-wieczorek.bsky.social

Thank you @embo.org for the honour of joining the EMBO YIP community! This would not have been possible without the efforts of our talented team at ETH Zurich and all our colleagues