Simon Bullock
@simonbullock11.bsky.social
📤 1349
📥 419
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Molecular motors, mRNA localisation, microscopes4schools, MRC-LMB (Cambridge, UK)
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Simon Bullock
Michael Way
3 days ago
Now for something completely different - Way lab does immunology - check out our
@science.org
paper - Branched actin networks mediate macrophage-dependent host-microbiota homeostasis. The work was driven by the 2 first authors
@luiz90vasc.bsky.social
@shainahuang.bsky.social
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Lots of exciting PhD projects on offer at the LMB, including in our group 😊
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7 days ago
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Tanmay Bharat
10 days ago
An Asgard archaeon with internal membrane compartments Brilliant study led by
@fmacleod.bsky.social
and Andriko von Kügelgen. Tight collaboration with
@buzzbaum.bsky.social
and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
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Vicki Metzis
25 days ago
I am absolutely delighted to share the invited speakers for our upcoming
@bsdb.bsky.social
"Molecules to Morphogenesis" meeting! Registration and abstract submission is now open - join us!
bsdb.org/meetings/
March 23-26, 2026 - UK
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Michalis Averof
25 days ago
How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵 Check our latest preprint
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A toolkit for testing membrane-localising tags across species
Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
https://www.biorxiv.org/content/10.1101/2024.11.12.623055v2
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Manuel Thery
about 1 month ago
We hire! The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities. More details here:
cytomorpholab.com/index.php/jo...
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ImmuNoah's Ark (Noe Rodriguez)
about 1 month ago
📣 Two week left to apply! 👇 Apply in the link below or, if you have specific questions, reach out!
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Alfredo Castello
about 1 month ago
Are you thinking on an exciting PHD project at the interface of translation control and innate immunity?
@rnanomad.bsky.social
and I have a project that might interest you!
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Michael Webster
about 1 month ago
Start independent research at the JIC with us 👇. Really interested in finding those with an interest in structural biology and biochemistry of plants and microbes. Please do get in touch by email if you'd like to know more 👍
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Siân Culley
about 2 months ago
BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share!
www.kcl.ac.uk/jobs/126345-...
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Bioimage Analysis Specialist | King's College London
https://www.kcl.ac.uk/jobs/126345-bioimage-analysis-specialist
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Sofya Garushyants
2 months ago
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
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Michael Way
2 months ago
And now for something completely different
@tianyang22.bsky.social
&
#YanCao
uncover of how SPIN90 dimers activate Arp2/3 to nucleate bidirectional linear actin filaments. Great collaboration with
@romet-jegou-lab.bsky.social
&
@carolynmoores1.bsky.social
#Cryo-EM
#Arp2/3
rdcu.be/eGoH4
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Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers
Nature Structural & Molecular Biology - Liu et al. show that SPIN90 dimerizes and binds two Arp2/3 complexes to nucleate two bidirectional actin filaments and the dimerization domain is...
https://rdcu.be/eGoH4
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Akaash Kumar
2 months ago
🚨Publication alert🚨 My first, first-author paper is now out in
@natphoton.nature.com
! Our paper describes an iterative spectral unmixing algorithm and eight-channel camera-based hardware we developed enabling unmixing of low SNR live-cell data at video rates.
www.nature.com/articles/s41...
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Multispectral live-cell imaging with uncompromised spatiotemporal resolution - Nature Photonics
A tree-like arrangement of dichroic mirrors and multiple cameras coupled with an iterative spectral unmixing algorithm enables multispectral imaging of live cells in up to eight spectral channels with...
https://www.nature.com/articles/s41566-025-01745-7
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EMBL Events
2 months ago
Are you ready for a symposium dedicated to microtubule dynamics, function, and structure? 🙌 #EESMicrotubules will bring together researchers who share an interest in microtubule biology and its relevance to health and disease 🩺 💻
s.embl.org/ees26-09-bl
#EESMicrotubules
✒️ Submit your abstract by 11 March
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Anestis Tsakiridis
2 months ago
A 6-month postdoc position is currently available in our group. The project involves the use of hPSC-based models to dissect the links between chromosomal copy number alterations, DNA damage and tumour initiation-please spread the word-closing date=29th Sept:
www.jobs.ac.uk/job/DON353/r...
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Research Associate (Stem Cell/Cancer Biology)
Research Associate (Stem Cell/Cancer Biology)
https://jobsite.sheffield.ac.uk/job/Research-Associate-%28Stem-CellCancer-Biology%29/1494-en_GB
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The winners of our schools microscopy competition have been announced 👇!
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2 months ago
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News from UK Research and Innovation
2 months ago
ICYMI: Simplifying access to MRC applicant-led funding
#MRC
#AcademicSky
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Simplifying access to MRC applicant-led funding
We’re introducing a new flexible research grant and removing closing dates from our board funding opportunities.
https://www.ukri.org/news/simplifying-access-to-mrc-applicant-led-funding/?utm_source=dlvr.it&utm_medium=%5Bbluesky%5D
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Marco MILAN LAB
2 months ago
EMBO meeting on "Molecular and Developmental Biology of Drosophila" 21 – 27 June 2026 Registration is now open! Deadline next November 3rd!
meetings.embo.org/event/26-dro...
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Molecular and Developmental Biology of Drosophila
The principal theme of the EMBO Workshop is the Molecular and Developmental Biology of Drosophila. Supported by EMBO over four decades, this will be the 24th biennial “Crete meeting”. With the a…
https://meetings.embo.org/event/26-drosophila
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Katja Röper
2 months ago
If you love cytoskeleton and tissue morphogenesis, have a read!
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Matthew Freeman
3 months ago
Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab
@dunnschool.bsky.social
by applying for sponsorship for early career fellowships. Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
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Group Leader Career Development Fellowships - Dunn School
Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?
https://www.path.ox.ac.uk/work-with-us/career-development-fellowships/
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Andreas Prokop
3 months ago
Dear GenZ members of the
#Drosophila
community! You are needed to make cool fly research viral in your social media world! As a boomer I do not understand that sphere, but I can consult and contribute our enormous fund of outreach resources:
droso4public.wordpress.com
. Please, get in contact!
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droso4public is a central resource store supporting science communication and advocacy for Drosophila
https://droso4public.wordpress.com/
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Elif Nur Firat-Karalar
3 months ago
New paper on DYRK kinases and primary cilium! This project began with our interest in DYRK3’s relationship to centriolar satellites. But what started as a CS-focused story soon evolved into studying DYRK kinase activity during ciliogenesis.
nature.com/articles/s42...
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Kinase activity of DYRK family members is required for regulating primary cilium length, stability and morphology - Communications Biology
DYRK3 kinase interacts with multiple centriolar satellites and ciliary components to regulate axoneme length dynamics in cooperation with DYRK2.
https://nature.com/articles/s42003-025-08373-5
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Simon Bullock
Michael Way
3 months ago
💥 Another Cryo-ET study from the Way lab by @miguel-virus-cells.bsky.social in collaboration with Rosenthal lab
@crick.ac.uk
examining Vaccinia virus egress 😀👇
www.biorxiv.org/content/10.1...
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In situ cryo-electron tomography of vaccinia virus exit from infected cells
Poxvirus-infected cells release newly assembled virions via Golgi-mediated envelopment and subsequent exocytosis at the plasma membrane, prior to cell lysis. Here, we used cryo-electron tomography and...
https://www.biorxiv.org/content/10.1101/2025.08.20.671218v1
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Simon Bullock
MRC Laboratory of Molecular Biology
3 months ago
We’re looking for a
#postdoc
to join Michael Hastings’ group, studying diet-induced neuroinflammation in the hypothalamus and its modulation by circadian clock mechanisms, in collaboration with John O'Neill's group.
www.nature.com/naturecareer...
Closes 08 SEP
#ScienceJobs
#PostdocJobs
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Simon Bullock
Cahir O'Kane
3 months ago
A beautiful model of an mRNA transport complex that looks like a Texas congressional district
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Simon Bullock
Griffiths Lab
3 months ago
Sometimes, knocking out a gene isn't a good way to figure out the function of that gene ... In our new
@jcellsci.bsky.social
paper, we report potent transcriptional adaptation by cytotoxic T lymphocytes (CTLs) in response to CRISPR/Cas9-mediated deletion of the important polarity protein CDC42 🧵⬇️
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Simon Bullock
Carter Lab
3 months ago
Excited to share our latest work with
@simonbullock11.bsky.social
! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before.
www.biorxiv.org/content/10.1..
.
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Our latest work, in collaboration with the terrific
@kashishsingh.bsky.social
in the Carter lab
@mrclmb.bsky.social
is out. So proud of this study and everyone involved...
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3 months ago
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Sjors Scheres
3 months ago
Fantastic work by the group of
@matteoall.bsky.social
: a SUN5:Nesprin3 complex at the head:tail junction of sperm cells. 🤯
#teamtomo
www.biorxiv.org/content/10.1...
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In-cell structure of a LINC complex reveals the molecular basis for membrane remodelling and head-to-tail coupling in sperm cells
In eukaryotic cells, LINC complexes physically bridge the two nuclear membranes to cytoskeletal filaments, transmitting mechanical forces to the nucleus. Due to their dynamic and membrane-embedded nat...
https://www.biorxiv.org/content/10.1101/2025.08.04.668116v1
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Aixa V. Morales
3 months ago
Our new work on the establishment of quiescence in
#adultneurogenesis
, done at
@institutocajal.bsky.social
@csic.es
, is out in
@plosbiology.org
. Proud of a Great team, Cristina Medina,
@paulatiradom.bsky.social
, Lingling Li ,
@pilar-rguezm.bsky.social
and the rest ! 🎊🎉🧠
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Phil Holliger
4 months ago
We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry (
www.jobs.ac.uk/job/DNW809/r...
) at the MRC Laboratory of Molecular Biology (LMB).
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Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology
Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...
https://www.jobs.ac.uk/job/DNW809/research-group-leader-in-chemical-synthetic-biology
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Liz Miller
3 months ago
Go check out the latest preprint from Giulia Zanetti's lab.
@dr-downes.bsky.social
used cryo-tomography to directly visualize COPI and COPII coated vesicles in situ at unprecedented resolution in human cells. Amazingly beautiful, rigorous, insightful work.
www.biorxiv.org/content/10.1...
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Multi-scale Molecular Imaging of Human Cells reveals COPI and COPII Vesicles at ER Exit Sites
Trafficking from the endoplasmic reticulum to the Golgi apparatus comprises the first steps toward the correct localization of 30% of eukaryotic proteins. Coat protein complexes COPII and COPI are inv...
https://www.biorxiv.org/content/10.1101/2025.07.29.667472v1
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Robert Arkowitz
4 months ago
Escherichia coli with a 57-codon genetic code | Science
www.science.org/doi/10.1126/...
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Escherichia coli with a 57-codon genetic code
The near-universal genetic code uses 64 codons to encode the 20 canonical amino acids and protein synthesis. Here we designed and generated Escherichia coli with a 4 Mb synthetic genome in which we re...
https://www.science.org/doi/10.1126/science.ady4368?utm_source=sfmc&utm_medium=email&utm_content=alert&utm_campaign=1stRelease&et_rid=17154784&et_cid=5690638
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Simon Bullock
Institute of Molecular Biotechnology
4 months ago
In 2025, the Brennecke lab revealed how ancient endogenous retrotransposons diversified like Darwin’s finches, each adapting to a specific cell type within the Drosophila ovary. Read more about the Brennecke Lab’s research:
imba.science/BrenneckeLab
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Esther Verheyen 🇨🇦
4 months ago
Fly folks - want to do RNAi in embryos to look at patterning. Haven't delved into this before - any suggestions of good Gal4 drivers?
#Drosophila
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Simon Bullock
Shane Herbert
4 months ago
If you’ve ever wondered how cells tune positioning of organelles in response to cell shape change, and what happens when this goes wrong, please check out our new manuscript – mRNA trafficking controls cell-size-scaled organelle dynamics!
www.nature.com/articles/s41...
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mRNA trafficking directs cell-size-scaling of mitochondria distribution and function - Nature Communications
How mitochondria positioning dynamically adapts to changes in cell shape is poorly understood. Here, Bradbury et al. show that cell-size-dependent trafficking of TRAK2 mRNA underpins the cell-size-sca...
https://www.nature.com/articles/s41467-025-61940-6#citeas
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PLOS Biology
4 months ago
In this new
#Biologue
post, we speak to Richard Hodge, a cancer editor at
#PLOSBiology
about the new Collection “Unveiling cancer crosstalk across spatial and temporal scales”, his background in
#CancerResearch
and his vision for
#cancer
biology at the journal 🧪
plos.io/3U6GXFW
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Jordan Raff
4 months ago
The Dunn School is a really great environment for taking up a Career Development Fellowship, and we are looking for candidates! Please spread the word.
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Lerit Lab
4 months ago
Our lab is looking to recruit a new postdoc to join our team. You can visit us at
leritlab.org
to learn more and submit applications here:
faculty-emory.icims.com/jobs/149999/...
(or scan the QR in the ad below!) Review will commence in early August.
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Eva Kowalinski
4 months ago
Postdoc positions in structural biology of RNA processing complexes. An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification. Details:
tinyurl.com/postdoc-RNA-...
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Postdoc in Structural Biology of RNA processing complexes
Postdoctoral positions in structural biology of macromolecular complexes are available in the laboratory of Dr. Eva Kowalinski at the EMBL Grenoble, France. We are looking for highly motivated and amb...
https://tinyurl.com/postdoc-RNA-cryoEM
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Julius Brennecke
4 months ago
Pls. share widely Calling all transposon fans & lovers of genetic innovation MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025 → Vibrant & friendly community → Cutting-edge talks from mechanisms to physiology → Plenty of surprises (TEs never stop innovating) submit abstract by July 29
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Prof Christina Pagel
4 months ago
The important characterisation of the UK pop'n from More In Common highlights v low levels of trust in most former 'authoritative' professions. Scientists are the exception. Trust both fragile & valuable. We scientists must continue to *earn* it. Science communication is more important than ever.
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Vicki Metzis
4 months ago
Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc! Multiple positions across multiple groups
@mrc-lms.bsky.social
Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇
lms.mrc.ac.uk/work/vacanci...
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MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences
Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.
https://lms.mrc.ac.uk/work/vacancies/mrc-postdoctoral-research-scientists-x-5/
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Lerit Lab
4 months ago
We will start reviewing applications for this research technician position next week. If you’re thinking of applying, I encourage you to submit this week. I am awaiting SOM approval for a postdoc hire and hope to advertise that position soon - stay tuned!
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Simon Bullock
MRC Laboratory of Molecular Biology
4 months ago
Excellent opportunity for a postdoc to join
@sjorsscheres.bsky.social
in the LMB’s Structural Studies Division to work on
#cryoEM
structure determination of amyloid filaments in a lively, multi-disciplinary group. Read more:
www.nature.com/naturecareer...
Closes 03 AUG
#PostdocJobs
#ScienceJobs
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Helen Walden
5 months ago
It’s too late on a Friday night for me to post sensibly about this work! But I’m super proud of Joanna’s determination to validate Parkin substrates and I love working with her robust and creative science!
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This is a very exciting opportunity! 👇
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5 months ago
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Joe Greener
5 months ago
Interested in a postdoc position combining computational protein design and molecular simulation? There is an open position in my group at the MRC-LMB in Cambridge, UK.
www.nature.com/naturecareer...
Feel free to message me with any questions.
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Postdoctoral Scientist - Structural Studies - Dr Joe Greener - LMB 2633 - Cambridgeshire job with MRC Laboratory of Molecular Biology (LMB) | 12840475
Postdoctoral Scientist Salary £41,344 per annum Fixed Term – 3 years MRC Laboratory of Molecular Biology, Cambridge, UK We are looking for a postd...
https://www.nature.com/naturecareers/job/12840475/postdoctoral-scientist-structural-studies-dr-joe-greener-lmb-2633
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Susana Godinho
6 months ago
👋 Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab! 👉 deadline 20/06 👇 check it out
www.godinholab.com
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FlyBase
6 months ago
We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.
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