Simon Bullock
@simonbullock11.bsky.social
📤 1364
📥 422
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Molecular motors, mRNA localisation, microscopes4schools, MRC-LMB (Cambridge, UK)
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Simon Bullock
Vincent Croset
2 days ago
🚨 Postdoc opportunity to study memory or nutrition in
#Drosophila
🪰 I am looking for a candidate to support for a 3 year Addison Wheeler Fellowship application
lnkd.in/e2rvNf5x
Interested? Please send a CV & cover letter with brief research outline by 20th February to
[email protected]
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addison-wheeler-fellowship - Durham University
https://www.dur.ac.uk/research/institutes-and-centres/advanced-study/fellowships-funding/addison-wheeler-fellowship/
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Simon Bullock
Marvin Tanenbaum
3 days ago
Out now in Cell Systems: We develop a technique to visualize influenza A virus in live cells with single viral RNA resolution. Combined with precise readouts of viral transcription, we map the whole influenza A viral life cycle and identify key bottlenecks in infection.
www.cell.com/cell-systems...
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Live-cell single-vRNP imaging identifies viral gene expression signatures that shape influenza infection heterogeneity
In this study, an imaging technology, “VISUN,” is developed that allows live-cell visualization of unmodified influenza virus during infection with single-vRNP resolution. Combining VISUN with multipl...
https://www.cell.com/cell-systems/fulltext/S2405-4712(25)00322-9
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Simon Bullock
Addgene
4 days ago
Thanks
@michaelboutros.bsky.social
and
@crisprflydesign.bsky.social
for sharing! 🧪🧬✂️🔬🪰 Multiplexed Cas12a editing plasmids here:
www.addgene.org/browse/artic...
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Simon Bullock
Suyang Zhang
10 days ago
One week left to apply for the postdoc position at MRC-LMB in Cambridge. Join our team for an exciting project on transcription-coupled splicing to understand human gene regulation 🧬 Feel free to get in touch directly
#postdoc
#cryoEM
#biochemistry
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Simon Bullock
theNiessingLabs
6 days ago
Searching for a human neural cell line with greater differentiation potential than SH-SY5Y cells? Check out the human
#neural
#stem_cell
line HNSC.100. Differentiates into astrocytes, neurons & oligodendrocytes. On
#BioRxiv
, we provide protocols, markers, ABs, karyotyping & RNAseq:
shorturl.at/y0aJG
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Simon Bullock
Helen Foster
9 days ago
Very happy to say that our work on how axonemes are generated is now available on bioRxiv:
www.biorxiv.org/content/10.6...
- if you’ve ever wondered how the incredibly beautiful, complex structures within motile
#cilia
are constructed then this is for you!
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https://www.biorxiv.org/content/10.64898/2026.01.30.702858v1
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Simon Bullock
Michael Way
9 days ago
Postdoc job alert in the Crick Institute in London. Are you interested in the actin cytoskeleton? I am looking for a postdoc to examine the cellular, developmental or physiological role of Arp2/3 iso-complex driven actin polymerisation. Multiple aspects available.
crick.ac.uk/WayPostdoc2026
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Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab
http://crick.ac.uk/WayPostdoc2026
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Simon Bullock
Michael Way
9 days ago
2nd postdoc job alert in the Crick Institute in London. Project will examine the role of motors & the cytoskeleton (actin, septins and microtubules) during vaccinia virus egress using biochemical, structural & cellular approaches + live cell imaging. spread the word.
crick.ac.uk/WayPostdoc20...
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Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab
http://crick.ac.uk/WayPostdoc2026-2
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Simon Bullock
Matthew Taliaferro
10 days ago
The registration deadline for this wonderful meeting is approaching! Be sure to reserve your spot before March 10!
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Simon Bullock
Matthew Freeman
11 days ago
This is for you – and a great opportunity – if you are establishing a group in Croatia, Czechia, Estonia, Hungary, Lithuania, Luxembourg, Poland, Portugal and Türkiye...
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Simon Bullock
Toby Andrews
13 days ago
Job alert! 📣 I’m looking for a research assistant to join my new team
@idrm.ox.ac.uk
Were using
#zebrafish
to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️🩹 Full info below, and please share! 🫶🏻
bit.ly/467TO0M
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Simon Bullock
Oliver Harschnitz
13 days ago
The IGNITION PhD Programme is now open! We’re offering 13 fully funded PhD positions across 10 institutions in 8 EU countries to study immune mediated neurodegeneration. If you're passionate about research, innovation & international collaboration, this is for you.
ignition-consortium.eu/home/
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This is another tour de force from
@crisprflydesign.bsky.social
and colleagues with consideration of utility for the community at its heart. Great work!
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16 days ago
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Simon Bullock
Cahir O'Kane
17 days ago
More efficient CRISPR targeting in Drosophila, via Cas12a and easier synthesis of multiplexed gRNAs
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Simon Bullock
Martin Turner
19 days ago
Just out
@natrevimmunol.nature.com
RNA-binding proteins and ribonucleoproteins as determinants of immunity
www.nature.com/articles/s41...
gives our perspective on this growing area of research. Special thanks to the editor Alexandra, for streamlining the manuscript.
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RNA-binding proteins and ribonucleoproteins as determinants of immunity - Nature Reviews Immunology
RNA-binding proteins (RBPs) considerably expand the information content of the genome and can determine the lifespan, localization and function of RNA, thereby controlling when, where and how much pro...
https://www.nature.com/articles/s41577-025-01254-2
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Simon Bullock
MRC Laboratory of Molecular Biology
19 days ago
Exciting opportunity for a
#postdoc
to join
@suyangzhang.bsky.social
’s group in the LMB Structural Studies Division to investigate co-transcriptional splicing using cryo-EM and biochemistry. Read more:
www.nature.com/naturecareer...
Apply by 11 FEB
#PostdocJobs
#ScienceJobs
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Simon Bullock
20 days ago
I’m happy to share the main result of my PhD, which you can find on bioRxiv
www.biorxiv.org/content/10.6...
. If you are interested in learning about a new way to perform DNA-PAINT multiplexing, which we call Combi-PAINT, or if you are interested in the study of mRNA conformation, keep reading! 1/10
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Simon Bullock
Lerit Lab
19 days ago
Hitting the postdoc search? Consider applying to be part of the Winship postdoc recruitment cohort
@winshipcancer.emory.edu
apps.winshipcancer.emory.edu/admin/Event/...
Eligibility requirements and participating faculty are listed in the link✅
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Winship Postdoctoral Fellow Recruitment Event
https://apps.winshipcancer.emory.edu/admin/Event/6605
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Simon Bullock
Kathrin Leppek
24 days ago
Tom Cech on RNA research in Davos (video):
www.weforum.org/meetings/wor...
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Simon Bullock
Andrew Bowman
24 days ago
Join us in Warwick for a fun two-day symposium and celebrate the career of Prof Rob Cross!
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Simon Bullock
Ivaska Lab
26 days ago
Postdocs wanted - Please spread the word! We are looking for one bioinformatician and 1-2 cell biologists with different expertise! See the job ad below for more information and links to the job descriptions!
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Simon Bullock
Andreas Prokop
26 days ago
Transport motor loss and hyperactivation cause axonal microtubule bundle damage mediated by inferred ROS dyshomeostasis upon motor loss, and through ROS-independent mechanisms, likely through increased mechanical load, upon motor hyperactivation
www.manchester.ac.uk/about/news/r...
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Research with fruit flies could unlock riddle of neurodegenerative disorders
A study by University of Manchester scientists using fruit flies as model has identified a mechanism which can explain aspects of neurodegeneration which have baffled scientists for decades.Scientists...
https://www.manchester.ac.uk/about/news/research-with-fruit-flies-could-unlock-riddle-of-neurodegenerative-disorders/
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Simon Bullock
Eugene Valkov
28 days ago
We are looking for a postdoc to work on mechanisms of
#RNA
decay in cancer using
#cryoEM
with
#nanobodies
and
#minibinders
! Please RT
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Simon Bullock
Journal of Cell Science
26 days ago
Climate change and cell biology – five ways cells can help us solve planetary problems An Essay from
@marennattermann.bsky.social
,
@sorayazwahlen.bsky.social
, Eric Yirenkyi Danquah,
@hannaszafranska.bsky.social
, Kavita Rangan &
@samreckpeterson.bsky.social
.
journals.biologists.com/jcs/article/...
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Simon Bullock
British Society for Cell Biology
26 days ago
We are looking for early career cell biology researchers to present their work at the BSCB NextGen online seminar series. Scan the QR code to register your interest:
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Simon Bullock
Steven Marygold
about 1 month ago
Proud of latest publication on
#Drosophila
#enzymes
at
doi.org/10.1093/g3jo...
, representing several years of diligent work enhancing fly enzyme annotations and display at
@flybase.bsky.social
and significant improvements of the
#GeneOntology
.
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Comprehensive annotation of the enzymes of Drosophila melanogaster
Abstract. We have completed a systematic survey of Drosophila melanogaster enzymes, improving the coverage and accuracy of their functional Gene Ontology a
https://doi.org/10.1093/g3journal/jkaf294
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Simon Bullock
Seema Grewal
about 1 month ago
We’re hiring!
@jcellsci.bsky.social
is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves
#cellbiology
and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community! Details below👇
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Simon Bullock
Alex Whitworth lab
about 1 month ago
Drosophila models have been highly useful in dissecting the physiological roles of PINK1 and Parkin in
#mitophagy
Led by 3 talented PhD students, we wrote a review summarising recent exciting discoveries and discussed these in context of current in vitro studies
portlandpress.com/biochemj/art...
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Simon Bullock
MRC Laboratory of Molecular Biology
about 2 months ago
Are you an enthusiastic and ambitious scientist looking for a challenging project? Come and join
@kellythd-nguyen.bsky.social
’s group as a Research Support Officer and help decipher the molecular mechanisms of telomere maintenance! Apply by 11 JAN
www.jobs.ac.uk/job/DPU715/r...
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Simon Bullock
MRC Laboratory of Molecular Biology
about 2 months ago
We’re looking for a Software Engineer to join Marco Tripodi’s group in the LMB’s Neurobiology Division, where you'll design and develop computational pipelines to acquire and analyse behavioural and neurophysiological data. More details:
www.nature.com/naturecareer...
Closes 04 JAN
#PostdocJobs
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Simon Bullock
MRC Laboratory of Molecular Biology
2 months ago
Excellent opportunity for a
#postdoc
to join Michel Goedert’s group, investigating the mechanisms which cause the formation of amyloid filaments in neurodegenerative diseases, in collaboration with
@sjorsscheres.bsky.social
’s group. More details:
www.nature.com/naturecareer...
Closes 04 JAN
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Simon Bullock
The EMBO Journal
2 months ago
A mechanism for controlling mRNA localization to neuronal projections: Daniel Dominguez, Matthew Taliaferro
@jmtali.bsky.social
and collaborators implicated ALS-linked TDP-43 as inhibitor of mRNA accumulation in neurites, possibly by promoting their decay
link.springer.com/article/10.1...
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TDP-43 directly inhibits mRNA accumulation in neurites through modulation of mRNA stability - The EMBO Journal
The subcellular localization of many mRNAs to neuronal projections allows neurons to efficiently and rapidly react to spatially restricted external cues. However, for most of these RNAs, the mechanism...
https://link.springer.com/article/10.1038/s44318-025-00653-4
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Simon Bullock
Samara Reck-Peterson
2 months ago
The Reck-Peterson lab at Weill Cornell Medicine is seeking a technician or staff scientist to work on Aspergillus projects. Broad background in fungal biology and techniques required. Bioinformatics skills preferred. Find out more at:
reckpetersonlab.org
.
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Simon Bullock
Patrycja Kozik
2 months ago
Time for a new pre-print! How do dendritic cells control pore formation in their own endocytic compartments? Our work shows that the unique transmembrane anchor of perforin-2 does not protect DC membranes, but instead it enables antigen escape during cross-presentation
doi.org/10.64898/202...
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Simon Bullock
Liz Miller
2 months ago
My excellent collaborator, Giulia Zanetti, is advertising for a post-doc to work on our shared MRC grant. Please consider applying to this great lab with a supportive mentor to do some exciting structural biology.
www.ucl.ac.uk/work-at-ucl/...
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UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs/details?nPostingId=16553&nPostingTargetId=39994&id=Q1KFK026203F3VBQBLO8M8M07&LG=UK&languageSelect=UK&mask=ext
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Simon Bullock
Sjors Scheres
2 months ago
Postdoc opportunity with Michel Goedert and myself to work on
#cryoEM/#cryoET
structures of
#amyloids
. Feel free to email me with any questions you might have.
mrc.tal.net/vx/mobile-0/...
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Postdoctoral Scientist - Neurobiology - Dr Michel Goedert - LMB 2752 - Medical Research Council
Location: Cambridge. Vacancy: Postdoctoral Scientist - Neurobiology - Dr Michel Goedert - LMB 2752. Closing Date: 04/01/2026, 23:55
https://mrc.tal.net/vx/mobile-0/appcentre-ext/brand-3/spa-1/candidate/so/pm/4/pl/1/opp/2752-Postdoctoral-Scientist-Neurobiology-Dr-Michel-Goedert-LMB-2752/en-GB
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Simon Bullock
Ruben Gonzalez
2 months ago
The Gonzalez Lab at Columbia University is seeking a scientific leader! Join us in a Research Scientist position, driving single-molecule, structural, and biochemical studies of translation, translational control, and other RNA-based processes. Apply:
apply.interfolio.com/176949
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My favourite meeting! Highly recommend registering for this one...
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2 months ago
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Simon Bullock
Michael Way
2 months ago
Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB
@ascbiology.bsky.social
in Philadelphia. Just drop me a line.
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Simon Bullock
MRC-LMB Cell Biology Division
3 months ago
See how far a PhD from
@cellbiol-mrclmb.bsky.social
can take you! Still a few days left to apply for a PhD place here to start in October 2026: www2.mrc-lmb.cam.ac.uk/students/int...
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Simon Bullock
Cathy Abbott
3 months ago
Two studentships available, one with me and Sam Booker and the other with me and Paul Donlin-Asp- do apply!
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
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EASTBIO Subcelllular compartmentalisation of eEF1A paralogous proteins in neurons across the lifespan at University of Edinburgh on FindAPhD.com
PhD Project - EASTBIO Subcelllular compartmentalisation of eEF1A paralogous proteins in neurons across the lifespan at University of Edinburgh, listed on FindAPhD.com
https://www.findaphd.com/phds/project/eastbio-subcelllular-compartmentalisation-of-eef1a-paralogous-proteins-in-neurons-across-the-lifespan/?p191713
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Simon Bullock
Paul Conduit
3 months ago
We are looking to hire a postdoc to work on the regulation of microtubule nucleation in neurons. See advert attached. Contact me by email for any extra info.
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Simon Bullock
Peter Mulhair
4 months ago
Latest work out today in
@currentbiology.bsky.social
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬 To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain). 🔗
tinyurl.com/2vyuevpy
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Revised evolutionary relationships within Brachycera and the early origin of bicoid in flies
Mulhair et al. uncover a functional bicoid in non-cyclorrhaphan flies, pushing the gene's origin back by ∼20 million years. Reassessing the Diptera phylogeny using the largest dataset to date permits ...
https://www.cell.com/current-biology/fulltext/S0960-9822(25)01251-5
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Simon Bullock
MRC Laboratory of Molecular Biology
3 months ago
Want to join the LMB as a PhD student in October 2026? You’ve got two weeks left to apply! Visit our website for more details:
www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.
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Simon Bullock
Michael Way
3 months ago
Now for something completely different - Way lab does immunology - check out our
@science.org
paper - Branched actin networks mediate macrophage-dependent host-microbiota homeostasis. The work was driven by the 2 first authors
@luiz90vasc.bsky.social
@shainahuang.bsky.social
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Lots of exciting PhD projects on offer at the LMB, including in our group 😊
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3 months ago
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Simon Bullock
Tanmay Bharat
3 months ago
An Asgard archaeon with internal membrane compartments Brilliant study led by
@fmacleod.bsky.social
and Andriko von Kügelgen. Tight collaboration with
@buzzbaum.bsky.social
and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
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Simon Bullock
Vicki Metzis
4 months ago
I am absolutely delighted to share the invited speakers for our upcoming
@bsdb.bsky.social
"Molecules to Morphogenesis" meeting! Registration and abstract submission is now open - join us!
bsdb.org/meetings/
March 23-26, 2026 - UK
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Simon Bullock
Michalis Averof
4 months ago
How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵 Check our latest preprint
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A toolkit for testing membrane-localising tags across species
Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
https://www.biorxiv.org/content/10.1101/2024.11.12.623055v2
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