New research led by @klekkos.bsky.social and @tillymommersteeg.bsky.social at the IDRM and DPAG has uncovered an essential role for oxidative metabolism in heart regeneration. Read the full paper here: www.nature.com/articles/s44... Read the overview of the study: tinyurl.com/2syythet

More new work from the lab! @idrm.ox.ac.uk @oxforddpag.bsky.social Do all zebrafish regenerate their hearts equally? Also featuring the Mexican cavefish☺️ Thanks to all co-authors and especially the incredibly talented DPhil student Kostas Lekkos who drove the project. #zebrafish #heartregeneration

Meet Antonio Garcia Guerra, a Postdoctoral Research Scientist in the Rinaldi Group, and our August featured member. Antonio's research focuses on cell-specific gene editing in neuromuscular disease. Find out more about his research: www.linkedin.com/feed/update/... @oxfordpaediatrics.bsky.social

How do you turn cutting-edge science into a business idea? We spoke with Dr Sophie Payne (IDRM, DPAG), a postdoctoral researcher, about her journey on the Oxford Venture Builder, where she pitched her enhancer-based gene therapy idea. Read the full interview: lnkd.in/dx27XkV8

🎉Congratulations to the IDRM's Professor Sarah De Val on being awarded the title of Professor of Cardiovascular Science by the University of Oxford 🎉 #CardiovascularScience #AcademicAchievement #WomenInSTEM

🎉Huge congratulations to Dr Nancy Stathopoulou, IDRM Transition Fellow @oxfordpaediatrics.bsky.social who has been awarded the BHF Intermediate Science Research Fellowship by the @thebhf.bsky.social. Nancy’s work focuses on epigenetics in cardiac development and congenital heart disease.

👋Meet Konstantinos Lekkos, a DPhil Student in the Mommersteeg group, and our most recent featured member. Kostas' research focuses on the role of oxidative metabolism in zebrafish heart regeneration. Find out more about his research: www.linkedin.com/feed/update/... @oxforddpag.bsky.social

🎉 Congratulations to Konstantinos Lekkos, a 2nd year DPhil student in the Mathilda Mommersteeg Group. Kostas won first prize at this year’s Oxford MRC-DTP Symposium with his talk on a novel discovery in zebrafish metabolism and heart regeneration. @oxforddpag.bsky.social

🚨 The Simões Group is hiring! Join Filipa's team here at the IDRM as a Research Assistant and help advance cutting-edge cardiovascular regeneration research. 🔗 Apply now: lnkd.in/eKiSHWht 📅 Deadline: Midday 1st August 2025

Tomorrow is #ResearchAppreciationDay2025! On the final day of our countdown, we’re spotlighting new work from the Thomas Roberts Group (Ahlskog et al.) that challenges a proposed strategy for upregulating therapeutically relevant genes. 🔬 Study: tinyurl.com/4sd3kc86 📰 Story: tinyurl.com/mka7f3j5

It is day 3 of our #ResearchAppreciationDay2025 countdown! Dr Filipa Simões and team reveal how immune cells shape the heart from the earliest stages and guide regeneration in species like zebrafish. 🔬 Read the review: shorturl.at/kIYBf

Next up in our countdown to #ResearchAppreciationDay2025, we are spotlighting public engagement at the IDRM! IDRM researchers took part in Pint of Science 2025, bringing research and more to local Oxford pubs. Thanks to everyone who helped make it happen! 🔗 Read more: shorturl.at/z3yUI

🔬 Research Appreciation Day 2025, Saturday, July 5th, is just around the corner. To mark the occasion, we will spotlight a different project from the IDRM each day until Saturday in our very own Research Appreciation Week!

👋Meet Claudio Cortes Rodriguez, a Postdoctoral Research Fellow in the Riley group, and our most recent featured member. Claudio's research focuses on uncovering the cause of defects in the heart wall. Find out more about Claudio's research: lnkd.in/ebKNJ-zE @oxforddpag.bsky.social

This #CleanAirDay, we’re highlighting the small changes and big ambitions shaping sustainability at the IDRM. Yesterday’s biodiversity walk through the Lye Valley was a good reminder of what we’re working to protect: clean air, healthy ecosystems, and time to connect with nature.

Truly heart galore here at @thebhf.bsky.social Reflections of Research competition! My vote goes to @selintuzuner.bsky.social beautiful cardiac organoid!! Have you voted yet? @idrm.ox.ac.uk @oxforddpag.bsky.social @ox.ac.uk #OxfordOrganoidHub

Exciting news! Dr Jacinta Kalisch-Smith, @jkalism.bsky.social, has been awarded a BHF fellowship to explore how placental blood vessels support fetal growth and development. Her research could change how we detect and prevent complications during pregnancy. 🔗 Read more: shorturl.at/OVzqq

🎓 The MRC/BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) is inviting applications for a fully funded DPhil studentship, based at the IDRM. Learn more and apply: lnkd.in/gb-mEX8K @oxforddpag.bsky.social

Find out how IDRM researchers raised over £1,300 for Muscular Dystrophy UK earlier this month through the Oxford Town & Gown 10k race and fundraising events. Their combined efforts helped raise awareness and support vital research into muscle-wasting conditions. Read more: shorturl.at/rP9RK

👋Meet Anna Catarina Ferreria, a Research Assistant in the Stathopoulou Group, and our most recent featured member. Catarina's research focuses on understanding how epigenetic factors contribute to congenital heart disease. Read more: lnkd.in/ezEdRRDm @oxfordpaediatrics.bsky.social

🐝 Today on #WorldBeeDay, we're celebrating the buzz around IDRM! Our garden is alive with pollinators, drawn in by our blooming flowers and purpose-built bug houses. Pictured below: a ladybird, a bee, and a snail. Small but important reminders of the role of biodiversity in healthy lives.

🫀Job alert 🧬 come and be our colleague! Join a BBSRC-funded consortium aiming to understand how the human heart develops - you will be contributing multimodal single cell & spatial transcriptomics data using zebrafish and human cardiac organoids as models. Learn more: www.heartdevelopment.org (1/4)

It’s #MentalHealthAwarenessWeek, and this year’s theme is community. Feeling safe, supported and seen, especially at work, makes all the difference to our mental wellbeing. Let’s build workplaces where people feel able to speak up and get the support they need.

The Hulme Junior Research Fellowship offers early-career researchers a unique opportunity to advance their careers. • Lead independent research projects • Publish in high-impact journals • Build multidisciplinary collaborations Deadline: 12 noon, Monday 19 May www.dpag.ox.ac.uk/work-with-us...

Researchers from the MDUK Oxford Neuromuscular Centre at IDRM ran the Oxford Town & Gown 10k in support of Muscular Dystrophy UK. Thanks to generous support and a successful bake sale, the team raised over £1,300. Congratulations to everyone who participated!

Just published! Our Review on how immune cells masterfully orchestrate heart development and regeneration. Beyond fighting pathogens, they're actually building & repairing your heart! Learn how cutting-edge technologies are driving therapeutic opportunities here www.sciencedirect.com/science/arti...

New research from the @oliverastone.bsky.social Stone Group shows that lymphatic endothelial cells can arise directly from mesenchymal progenitors, bypassing venous endothelium. Read our conversation with the researchers to learn more: lnkd.in/dSV7W-8r 📄 Paper: lnkd.in/gz5v_ibH

Today on #WorldImmunologyDay, we're spotlighting the immune system with this image, shared by DPhil student Andreas Tarcevski (Holländer group). It shows a cross-section of an embryo mapped for gene expression. In blue, we see the thymus - a key organ for adaptive immunity and T-cell formation.

👋Meet Ambra Speciale, a DPhil Student in the Rinaldi Group, and our most recent featured member. Her research focuses on understanding how changes in RNA editing contribute to neurological disorders. Read more lnkd.in/ezHzDZCp or hear Ambra talk bsky.app/profile/idrm... @pintofscience.uk

Come and quench your thirst for knowledge at the @pintofscience festival Oxford, 19–21 May 2025! #pint25 The Battle Against Our Own Genes: learn about treating rare genetic disorders from the IDRM's Stephan Sanders and Ambra Speciale Grab your tickets here: pintofscience.co.uk/events/oxford

🌍 Happy Earth Day! At IDRM, we believe in world-changing science and everyday sustainability. From coffee log recycling to greener labs, small actions add up 🌱 #EarthDay2025 #GreenLabs

In view of the upcoming holiday, we'd like to wish you Happy Easter from all of us at the IDRM! 🔬 Hope your weekend is filled with egg-citement, rest, and a few sweet experiments🧪 #Easter #IDRM #Oxford

April is #StressAwarenessMonth — a perfect time to reflect on wellbeing in the workplace. Anna K. Shaffner, who previously gave a wellbeing seminar at the IDRM, reminds us that: “Exhaustion is a warning sign... We must allow ourselves guilt-free breaks.” #MentalHealth

Congratulations to the IDRM team who helped raise over £3,400 for @thebhf.bsky.social in this year’s Go Red Challenge 🎉 Oxford placed second nationally, with creative fundraising events including bake sales, a wine & cheese night, and CPR training. Read more: lnkd.in/dudTWsbY

This #WorldHealthDay, we highlight the urgent need for better maternal and newborn health. At IDRM, our research into cardiovascular, neuro, and immune development helps tackle lifelong health risks, starting before birth. Healthier beginnings lead to hopeful futures. #HealthyBeginnings

📢 EDI Seminar We're excited to welcome Dr Cressida Ryan back to the IDRM where she will take us through 'practical tools for supporting neurdivergence in the higher education workplace'. Wednesday 30th April | 11:30-12:30 All welcome - register here: lnkd.in/gQWUG8ku #EDI #Neurodiversity

🎉 Congratulations to Jacinta Kalisch-Smith who has just been awarded a 5 year Intermediate Fellowship from the British Heart Foundation. Her fellowship will study how placental blood vessels develop to understand the cause of neonatal heart conditions from early pregnancy @oxforddpag.bsky.social

👋Meet Eva Smpokou, our Paediatrics Departmental Safety Officer & IDRM Laboratory Manager, and our most recent featured member. Eva has a PhD in Occupational and Environmental Medicine and enjoyed a teaching Lab Technician role before moving towards Lab Management. Find out more: lnkd.in/e3YYWv8G

Great work coming out of @saradv.bsky.social at @idrm.ox.ac.uk, getting the spotlight from Guille Luxán (not on Bsky). What makes a vessel? And more importantly, what regulates and maintains different vessel identities?? Read below to find out..

🚨 Postdoctoral Research Associate Job Opportunities Passionate about cutting-edge cardiovascular research? Join the MRC/BHF Centre of Research Excellence (CoRE) in Advanced Cardiac Therapies (REACT)! 🔗Apply here: lnkd.in/e4mk9_DT 📅Deadline: 1st April 2025 📌Indicate which post you are applying for

♻️ Happy Global Recycling Day! ☕🌍 We love coffee - it fuels our research and brings our teams together! But we don’t love the waste. So instead of going to landfill, our coffee grounds get recycled into coffee logs which helps to reduce our carbon footprint! #GlobalRecyclingDay #RecycleAndReuse

📢Calling All Postdocs! Ready to take the next step in your research career? Our Transition Fellowship Programme is open for applications. Push boundaries, bridge research disciplines, and shape the future of regenerative medicine! 👉Apply now lnkd.in/eAErufG4 @oxfordpaediatrics.bsky.social

✨ We are celebrating #BritishScienceWeek with groundbreaking research at the IDRM! We bring together world-leading scientists to tackle some of the biggest challenges in cardiovascular, neurological, and immune system diseases. Here are just a few ways we’re making an impact 👇

The Stone Group's David Grainger has been shortlisted in the Node-FocalPlane image competition 🎉 Show your support by voting for his image: 🔗https://thenode.biologists.com/vote-for-your-favourite-image-in-the-node-focalplane-image-competition/photo/ @oxforddpag.bsky.social @the-node.bsky.social

🔬 Today is Rare Disease Day, a day to raise awareness for 400M people with rare diseases. Learn about the IDRM researchers developing new therapies for neuromuscular and neurodevelopmental conditions to turn science into impact. #RareDiseaseDay #RareDiseases

Explore the Human Body with Virtual Reality (VR) This exciting event is a collaboration between the Radcliffe Science Library and Department of Physiology, Anatomy, and Genetics (DPAG). 📅 Tues 4th March 🕐 9:30-10:30 or 10:50-11:50 Booking&more info https://buff.ly/3EPqfGq

👋Meet Sarah Sigal, a Research Assistant in the Riley Group, and our most recent featured member. Sarah supports a wide range of cardiovascular research projects and masterminds the annual IDRM Christmas Bake Off contest. Find out more here: lnkd.in/efYPsdsV @oxforddpag.bsky.social

Two months into 2025, and a second front cover in Nature Cardiovascular Research! 🎉 Congratulations to the Riley Group on their latest publication - another fantastic achievement for our cardiovascular research teams! 📖 lnkd.in/entuBfFa #CardiovascularResearch #NCVR @oxforddpag.bsky.social

Celebrating the impact of apprenticeships! 🎉 To finish off National Apprenticeship Week, we’re sharing insights from colleagues on the value of apprenticeships in their teams. Here’s what Tumi Akomolafe had to say about our apprentice, Joe Day: www.linkedin.com/posts/instit...

Celebrating the impact of apprenticeships! 🎉 We asked colleagues to share their thoughts on the value of apprenticeships within their teams. Here’s what Andy Darley had to say about Andrew Brogden who is currently pursuing a Team Leader apprenticeship: www.linkedin.com/posts/instit...