We had a fantastic time at the Ribo-Seq workshop in Bonn. Thanks so much, Kathrin @katleppek.bsky.social and Ranen, for organizing! We learned a lot, and we're excited to use Ribo-Seq in future projects.

We are well into our 5-day Cluster Workshop on Ribosome Profiling (Ribo-seq) run by sabbatical scientist Ranen Aviner @czbiohub.bsky.social. We welcome PhDs and PIs from Bonn/Cologne for a hands-on and analysis course sponsored by the Cluster @immunosens.bsky.social @unibonn.bsky.social UKB.

Last Friday, we had an inspiring 10th Rhineland RNA Club meeting with top class speakers. It's great to see how the community is growing and the range of topics we're covering. Special thanks to Didier Stainier @stainierlab.bsky.social Simon Bekker-Jensen @bekkerjensenlab.bsky.social, Ranen Aviner!

It was a double ribosome talk day for us in Bonn with talks today by Ranen Aviner from @czbiohub.bsky.social and Simon @bekkerjensenlab.bsky.social from BRIC Copenhagen. Simon is visiting for the @rhinelandrna.bsky.social tomorrow and Ranen is a visiting scientist in my and Ina‘s lab. #RNAsky

Lab pumpkins 🎃 2025. Vivian, Ranen, Martin and Lisa were missed (2 people not from our team).

We would like to invite all Rhineland RNA enthusiasts to attend our next series of in-person talks, featuring local and invited speakers. Highlights include the external talks by Didier Stainier, Simon Bekker-Jensen and Ranen Aviner. Please, register: tinyurl.com/RhinelandRNA

🎓RNAmed met at LMU on May 19 for a Topic Day on the immune recognition of RNA. Special thanks to Prof. Veit Hornung, Prof. Kathrin Leppek, and Prof. Min Ae Lee-Krisch for sharing their insights & joining the panel discussion. 📅On May 20, PhD students shared their methods in our first Methods Seminar

I often think it would be great to have chloroplasts, do photosynthesis, and live off the sun.

Kathrin is definitely larger than life! Best recruit ever!!

This massive poster of the ad campaign for the new recruits at the @unibonn.bsky.social is the nerdiest version and the closest I’ll ever get to a superhero movie poster. #Bauzaun

“Government plays an incredibly important role in supporting innovative work and discovery research,” Nobel laureate Jennifer Doudna tells Jeffrey Goldberg at #TAF25. This is work that “just doesn’t get done in companies.” Watch here: bit.ly/46a5DUE

Many transcriptome regions are translated but not known to encode proteins. They remain poorly annotated and thus under studied, partly due to the lack of terminology for these features. In @natmethods.nature.com we propose using "Translon" for any region decoded by the ribosome

We are happy to finally present our brand new lab website of the Leppek Lab! About time after 3.5 years of the lab. Perfectly in time for the #EMBLProtein meeting in Heidelberg where our 4 PhDs have posters and I have a talk! We would be happy about any feedback! 🎉 leppeklab.org

Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!

🎉 We’re excited to share our very first preprint!! 🎉 "Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells" 👉 doi.org/10.1101/2025... #FirstPreprint #StemCells #Metabolism #Epigenetics #AcetylCoA #HBP #Pluripotency #NewScience

We’re #hiring! 2 #post-doc positions for an interdisciplinary project funded by the @hfspo.bsky.social in #axolotl and #Drosophila #wound healing at @sickkidsto.bsky.social #Canada and @umontpellier.bsky.social #France @laghalab.bsky.social. Share and apply here: www.nature.com/naturecareer...

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

Happy 1000th citation anniversary, dear review ;)

The 9th Rhineland RNA Club on 1AUG #RNADay with great local speakers and @lenasteckelberg.bsky.social as invited speaker from Columbia was a super fun and well attended event with lots of #RNA discussions and networking. Organized and hosted by @katleppek.bsky.social at @dzne.science. #RNAsky

Reminder for the Rhineland RNA Club this Friday (1st AUG)

The 70s in RNA were quite a time.

Proud to share our work where we resolved a longstanding question regarding the existence of a human telomerase dimer and provided insights into its function. Led by 3 amazing lab members in collaboration with @yiliangding.bsky.social and @rdaslab.bsky.social. www.science.org/doi/10.1126/...

This week, we welcome Lana Ho (right), PhD student from @mengmengfu.bsky.social's lab at @ucberkeleyofficial.bsky.social, to our lab to teach us some cool smFISH (in a heatwave) as part of a lab exchange in the @hfspo.bsky.social Early Career Award.

Back to the roots. Literally. It's been a while since my days of working on plant riboswitches with Breaker people. I kind of missed the combination of a dirty bench and RNA work. This time, we want their ribosomes for a crazy idea. #RNA

After recent visits to the Munich RNAmed Day and Tampere(FIN) RNA Club, I was happy to return to Heidelberg for their #RNA Translation Club Retreat. Fun fact: For me, first time all my 3 TAC members (Georg Stoecklin, Bernd Bukau, Matthias Hentze) were in one room since my PhD defense. Fun times! ;)

Hello! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @cp-cellreports.bsky.social, @mardakheh.bsky.social and I highlight new RNA-focused tools for discovering RNA interactions across organizational scales. Checkit! tinyurl.com/ydn6e3ac

We are very happy to invite you to our 9th Rhineland RNA Club at @dzne.science Bonn with great local speakers and Lena Steckelberg @lenasteckelberg.bsky.social as our invited speaker. All #RNA enthusiasts are welcome! Organized by @inahuppertz.bsky.social and @katleppek.bsky.social. #RNAsky

The #ClustersOfExcellence have been selected: today, the Excellence Commission approved 70 projects for funding. 45 clusters will continue and 25 will be newly established. Funding starts on 1 Jan 2026 for 7 years, with €539 million per year. The full list: www.dfg.de/resource/blo... 1/3

Hurray! ImmunoSensation will go on! 🥳 The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded! Let us #celebrate 7 more years of #immunology in #Bonn 🎉 www.immunosensation.de/news/immunos...

Check out our own Philipp Koch in the @immunosens.bsky.social Cluster "Spot On Science" interview highting junior researcher's achievements. Philipp talks about his recent co-first author paper! Paper: www.embopress.org/doi/full/10.... PR: www.immunosensation.de/news/startin... @embojournal.org

Finally a clue made for people like me.

I am happy to share the latest paper from the lab. We detail a tripartite cell-free translation system based on the separation of mRNAs, ribosomes and ribosome-depleted cytoplasmic lysate from human cells, allowing for flexible reconstitution of translation reaction. #RNA #Ribosome

Come join our team! We have an opening for a research associate ("Ratsstelle"). Expertise in nucleotide chemistry and LC-MS is required. 👉 job-portal.lmu.de/jobposting/b... Deadline for application is June 01, 2025.

The 8th Rhineland RNA Club with great local speakers and Julian König @koenig-lab.bsky.social as invited speaker was a fun and well attended event with lots of #RNA discussions and networking. Organized and hosted by @inahuppertz.bsky.social at @mpiage.bsky.social. #RNAsky

Press Release for our recent @embojournal.org paper: www.ukbnewsroom.de/startpunkte-... English PDF version: www.ukbnewsroom.de/wp-content/u... Universitätsklinikum Bonn @unibonn.bsky.social @immunosens.bsky.social

The lab just got a tube holder upgrade thanks to the brother with the 3D printer. #TimelineCleanse

The crux of rigorously characterizing #IRES: Kathrin Leppek @katleppek.bsky.social, Maria Barna and colleagues compile a toolbox of approaches to study internal #ribosome entry sites in mammalian cells and embryonic tissues www.embopress.org/doi/full/10....

The first paper from the Leppek lab is published today at @embojournal.org!! 🎉 We designed and evaluated a versatile toolbox for determining IRES activity in cells and embryonic tissues. www.embopress.org/doi/full/10....

Get in touch with your colleagues at Columbia University.

Exciting new work from Barna Lab @stanfordmedicine.bsky.social www.science.org/doi/10.1126/...

We are very happy to invite you to our 8th edition of the Rhineland RNA Club @mpiage.bsky.social with great local speakers and Julian König @koenig-lab.bsky.social as our invited speaker. All #RNA enthusiasts are welcome. Organized by @katleppek.bsky.social and @inahuppertz.bsky.social. #RNAsky

Congrats Adele and Zijian and team!

Ribosomal expansion microscopy reveals a subcellular map of translational machinery composition and regulation at the single-molecule level www.science.org/doi/10.1126/... @science.org

The Leppek lab under water for carnival. 🐙 #ribosometentacles

Back to this changed version of the US for a 2-week SF/LA/NYC tour. #science

The lab just got its first own grant! wohoo! 🎉 #RNA

I Used to Run the N.I.H. Here’s What Worries Me. www.nytimes.com/2025/02/14/o...

First in-person retreat of our #HFSP team in Berlin hosted by Drago Milovanovic at the Charite bringing Utrecht, Bonn and Berkeley (on Zoom) together to report, discuss and brainstorm about our fun Early Career Award joint project with all team members.

#WomenInScienceDay today and every day. 💪

Randomly spotted a good friend of mine here ;)