Belated post… last year, our lab painted a glia mural! It took about 1 day and we used a projector for tracing. Can you guess which cell is which?

New preprint from the lab 🎉: γ-tubulin is a novel target of the tubulin autoregulation pathway! Previously thought to exclusively target α- and β-tubulin mRNAs, we show that the TTC5–SCAPER–CNOT11 axis also degrades γ-tubulin mRNA, expanding the scope of this fundamental regulatory mechanism.

Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there?? #CellBiology #WTFology www.biorxiv.org/content/10.6...

@hhmi.org Summer Undergraduate Research Experience - #CechFellows named in honor of Prof Tom Cech Deadline to apply: 12/22/2025 Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!! www.hhmi.org/programs/cec...

One of my Oxford visit highlights? I got to see these priceless slides that Ruffini sent to Sherrington of various sensory end organs. And yes, Ruffini had to excise these receptors from his own skin 😳🔬🧠

Excited to share our new pre-print collab w. @rdaslab.bsky.social Study led by Ved Topkar brilliant MD/PhD student who used biochemistry and bioinformatics to probe the relationship between Mbp mRNA structure & transport/local translation in oligodendrocytes! biorxiv.org/content/10.110… 1/8

Study from Mayo Clinic on deep brain stimulation (DBS) for multiple sclerosis (MS) patients. Not currently FDA approved but promising!

We have an exciting PhD position available in the Williams lab related to cerebral small vessel disease and funded through our Racing Against Dementia project - if you are interested then do apply here: regenerative-medicine.ed.ac.uk/postgraduate... www.findaphd.com/phds/project...

The UNC Department of Biology is seeking a Director of Biology Teaching Labs, a key leadership role overseeing our undergraduate laboratory program. 1/n Learn more and apply here: unc.peopleadmin.com/postings/308...

Well deserved! 👏

Two tenure-track faculty positions open in our department: 1) Microbial Ecology and Evolution careers.rpi.edu/en-us/job/49... 2) Cellular Neuroscience careers.rpi.edu/en-us/job/49... Join our collaborative, interdisciplinary community, which has proved to be a fantastic place to start a lab!

The NIH institute director firing last Friday is very bad. I made a video explainer about why. Stay for last post, w link to @science.org story from @jocelynkaiser.bsky.social 1/4 🧪

This is the creepiest Halloween decoration I’ve ever seen… IRL it’s very lifelike 😱 # BerkeleyLife

Reposting link: www.biorxiv.org/content/10.1...

Excited to share our preprint on cytoskeletal organization in astrocytes! biorxiv.org/content/10.110… Postdoc @mewynne759 looked at microtubules, IFs/GFAP & actin along long elaborate processes. Wonderful to collaborate w postdoc @dharshinigopal & @NogalesLab on cryo-ET 🤓 1/x

Meet the 2025 ASCB Award Winners—trailblazing scientists honored for research, mentoring, education, and innovation. Celebrate excellence across all career stages in cell biology. Read more: www.ascb.org/society-news...

Powerful stuff!

Saw a family of quails! How many do you see?

Deepika Dogra, Karin Tuschl, and I are thrilled to host the Neural Disorders RIG meeting of the @ZDMSociety on July 30, 10:00-11:30 am ET. We have a fantastic line-up of speakers. Register here: zdmsociety.org/2025-zdms-ri....

This week, we welcome Lana Ho (right), PhD student from @mengmengfu.bsky.social's lab at @ucberkeleyofficial.bsky.social, to our lab to teach us some cool smFISH (in a heatwave) as part of a lab exchange in the @hfspo.bsky.social Early Career Award.

Vaults are cool! What do they do? We don’t know!

Really beautiful study from Mike & collaborators! Basic cell biology question: how do axons know how long to grow? Important implications for PNS & CNS injury. Unexpected link between retrograde signaling & transposon/lncRNA mediated feedback! Wonderful demonstration of omics use & team science!

As the incoming Chair of Biochemistry and Biophysics at Weill Cornell Medicine, I am looking for a Director of Research. Exciting opportunity for a PhD scientist to shape the future of this new Department! Apply here: jobs.weill.cornell.edu/NY/job/New-Y...

Saw some cool mushrooms on campus today! Near Euclid and Hearst. en.m.wikipedia.org/wiki/Clathru...

The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants. www.spencer.org/grant_types/...

My dear health equity peers, the Robert Wood Johnson Foundation is doubling down on their DEI efforts. 💪🏽 Here’s a grant opportunity tinyurl.com/3pnxhy2d with a rapid response option those whose “health equity research projects have lost federal funding.” ⭐️ Please share ⭐️

Important to celebrate trainee victories: excited to have Holly Merta's @hollymerta.bsky.social paper out! We use TurboID sub-organelle proteomics to map the ER network. We find calmin/CLMN, an ER-to-actin tether regulating focal adhesions & cell motility. www.sciencedirect.com/science/arti...

Great This American Life episode: www.thisamericanlife.org/857/transcript So important now more than ever to have a solid biology education! Judge Ana Reyes on the EO banning transgender military personnel: “this executive order is premised on an assertion that's not biologically correct…

In these trying times, grateful for little kindnesses 🥰 Spotted on my walk home! #BerkeleyLife

Face palm! This is just an excuse… The computers go to sleep very quickly then need a password to login in even with PIV card. I often left mine in my office when I was in the lab. One time I found a PIV card and returned it.

Jennifer Doudna: I would not be here if not for NIH training grants! UC Berkeley @standupforscience.bsky.social

Excited to finally have this published! Out today in @naturecomms.bsky.social, we show that following demyelination in a mouse model of Multiple Sclerosis, treatment of senescent microglia with senolytics leads to improved remyelination. www.nature.com/articles/s41... 1/3

I just wrote a book about how the type of work @markhisted.org is doing is key to breaking through the bottlenecks holding back new treatments for brain and mental disorders (from Alzheimers to depression). Seeing his work in danger makes me ill, and angry. We must @standupforscience.bsky.social.

One of my students was accepted to this program earlier this month and asked me what’s going on? 😞 Dr. Milgram cares a lot about all trainees at the NIH. This must be a gut punch.

Two new opportunities in Edinburgh: Research technician in our lab elxw.fa.em3.oraclecloud.com/hcmUI/Candid... Senior research technician to support the Zebrafish Imaging and Screening Facility elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Roughly 9% of NIH employees fired yesterday - rumors are IC directors may be next. Please call your senators and representatives!

So sad to see this is the result of top NIH officials following federal court orders. For non-govt folks, retiring means he can keep his pension 😞 For those more politically savvy than me, is it time to start impeachment or is that a dead end in a Republican controlled Senate, House, Supreme Court?

So important for our scientist colleagues in states that voted for Trump to reach out to their Senators, reps, and state reps (to join the federal lawsuit). A cut to indirects will affect the hardest working & least appreciated folks in science: our custodians, animal techs, grants admins, etc. 😞

Giving access to SSNs, other data on government employees to non-employees like Musk is a violation of 5 USC 552a, and carries with it a penalty of $1000 per person whose data was accessed. We are building a case. Govt employees who want to participate should contact me directly

Has anyone received NIH funding (actual money in campus accounts) after this restraining order from Friday was issued? I’m particularly anxious about a diversity fellowship that we sent JIT info for 2+ weeks ago. nsf-gov-resources.nsf.gov/files/TRO-NY...

Tough times call for nerd humor! Just taught action potentials this week…

If you’re a federal govt employee targeted for leave or termination on the basis of your DEI work, please file an EEO (Equal Employment Opportunity) complaint & retain legal counsel. I’m a former NIH PI. Happy to refer you to a law firm that has successfully sued the govt many times! Pls repost 🙏❤️