The lab went to our institute Halloween party as research models- spot yeast, human, E.coli, naked mole rat, axolotl, fusing organoid, frog, drosophila, excitatory neuron and oligodendrocyte!!!

We have an exciting PhD position available in the Williams lab related to cerebral small vessel disease and funded through our Racing Against Dementia project - if you are interested then do apply here: regenerative-medicine.ed.ac.uk/postgraduate... www.findaphd.com/phds/project...

Amazing talk by Karl from our @annawilliamslab.bsky.social (who was also nominated for the Wilmut Prize) about his PhD work on Oligodenrocyte Progenitors and their differentiation potentials at the CRM away day.

The Edinburgh participants at dinner at VasCog!

Ronja gets the top abstract prize at Vascog!!

The lab is having a good few months for publications with this one as well in case you missed it: doi.org/10.1016/j.ym... www.sciencedirect.com/science/arti... (Thank you Themis and Francesca, and all!)

Our new paper on metformin, myelin, mitochondria and metabolism is now out at rdcu.be/eDbFD Thanks to Nina and all of the team!

Now out in Molecular Therapy! With Francesca Vacante, we describe MYRACL, a novel candidate lncRNA driving human oligodendroglia differentiation & myelination. Grateful to our amazing co-authors & mentors @annawilliamslab.bsky.social & Andrew Baker! Read more👇 www.sciencedirect.com/science/arti...

On National Receptionist's Day we would like to thank our fantastic reception team for all they bring to our Institute. They are the friendly face of IRR and help make our staff, students and visitors feel so welcome. Thank you! #NationalReceptionistsDay

For those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker www.nature.com/articles/s41...

EDINBURGH AXOLOTLS! Super-excited to hear my wonderful colleague @aidarodrigo.bsky.social on BBC Radio 4 talking about the axototl colony she has established in our institute @edinuni-irr.bsky.social 😃 Available on BBC sounds: Aida's section starts at 23.37 www.bbc.co.uk/sounds/play/...

Genetic subtypes predict multiple sclerosis severity and response to treatment #NeuroDegeneration 🧪🧠 http://medrxiv.org/cgi/content/short/2025.04.15.25325853v1

📣 Open call for early-career composers. 📣 The successful applicant will be invited to collaborate with the choir in a composition, and receive £1000 upon completion of the work. 🔹Deadline: 25th April 2025 🔹Details: caltonconsort.org.uk/compose/

Today I met @rodtmitchell.bsky.social at our Fringe bootcamp. We will be representing the @edinuni-irr.bsky.social at the @edfringe.bsky.social this year! Super excited. Lot's of thought-provoking talks by amazing academics - stay tuned!

The findings from my focus group project on #dementia and #multimorbidity are now available to download as an infographic Thanks to the Global Brain Health Institute and @nrs-ndn1.bsky.social for supporting this work. It was an enjoyable and illuminating process! www.gbhi.org/projects/exp...

"Neurons are like trees with roots and branches that talk!" was my favourite comment from a 4-year old from my last workshop for #BrainAwarenessWeek at the Little Muslims children's group. Thanks @edinuni-irr.bsky.social and @edinunineuro.bsky.social for the support!

Book now at www.ticketsource.co.uk/calton-consort #choral #whitacre #tallis #liveperformance #edinburgh #acappella #sadmusic

"Your brain is your superpower!" was the takehome message of my second workshop for #BrainAwarenessWeek2025. So glad to represent @edinuni-irr.bsky.social and @edinunineuro.bsky.social again at Danderhall Primary School.

It’s international woman’s day! Well we have a lot of amazing women in our group to celebrate from our fierce leader @annawilliamslab.bsky.social to our PhD students, postdocs, bioinformaticians, and everyone in between💪🏻 Thank you ladies for being amazing scientists, colleagues and friends 💜💙🩵

Looking for a #postdoc in #regenerative #biology? 🔬🧬Look no further than this amazing opportunity with my super office mate @aidarodrigo.bsky.social at @edinuni-irr.bsky.social to explore regenerative capacity across species! 🐭 🐁 Closing 📅 01/04/25

Book your tickets in advance at www.ticketsource.co.uk/calton-consort 7:30pm Saturday 22nd March Canongate Kirk

Delighted to announce @rikeshrajani.bsky.social as the first Group Leader to join our flagship vascular dementia research centre with @thebhf.bsky.social 🎉👏 The Rajani Lab will investigate how the protective myelin sheath around brain cells is damaged in small vessel disease👉 buff.ly/4hIGaVM

onlinelibrary.wiley.com/doi/full/10.... Hot off the press! We find changes in oligodendrocytes that lack FMRP! An excellent collaboration supported by @sidb-edinburgh.bsky.social .

I was thrilled to receive this news—I’ve been awarded the #MSCAPostdoctoralFellowship for my project, PHOS-SVD! Extremely grateful for the support of @annawilliamslab.bsky.social, @nadlerlab.bsky.social and my colleagues for their feedback. Excited to begin the journey into membrane lipid research!

Book now at www.ticketsource.co.uk/calton-consort

Soon we'll be starting a new research study looking at #MRI imaging of spinal cord in people with multiple sclerosis #MS Congrats @rozannameijboom.bsky.social from our imaging team on being awarded @mssocietyuk.bsky.social funding for this important study. www.annerowlingclinic.org/about/news/n...

⚠️Useful!⚠️ Protocol for assessing myelination by human iPSC-derived oligodendrocytes in Shiverer mouse ex vivo brain slice cultures by Themistoklis Tsarouchas, @erinmgibson.bsky.social @lidazoupi.bsky.social @annawilliamslab.bsky.social #neurosky www.sciencedirect.com/science/arti...

The weather may have been lamentable today here in Edinburgh thanks to #eowyn, but the good news is that tickets are now on sale for our next performance: Lamentations - A choral programme of ancient and contemporary perspectives on love, loss, and faith. www.ticketsource.co.uk/whats-on/edi...

This week we met with the researchers from our VIDA Doctoral Training Centre! It was a fantastic opportunity to network, discuss future ideas and collaborations, and enjoy research talks from the students and their supervisors. Learn more about the VIDA DTC: www.alzheimers.org.uk/research/our...

“The impact of the collective executive orders and directives appears devastating.” scim.ag/40ureTO

Couple of opportunities up to join the group! One at postdoc level, but open to senior support path. One research assistant role. Please share, or drop a line if you want to learn more! Or just apply! Thanks! elxw.fa.em3.oraclecloud.com/hcmUI/Candid... elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

More incredible speakers lined up for SCMND2025 - in the first of two sessions focused on 3D models of neurodegeneration! Submit your abstract before 31/01/2025 and register now! scmnd.com @cbdresearch.bsky.social @selinawray.bsky.social @annawilliamslab.bsky.social @edinunineuro.bsky.social

First post at this side. Latest axon diameter action led by Jenea Bin, in collaboration with Nolan, Mobius, Monk, Werner, and Emery labs. www.biorxiv.org/content/10.1...

Promising new cell therapy for liver disease shows positive results! Results from the MATCH trial, run by Stuart Forbes' lab in the Centre for Regenerative Medicine, were published in @nature.com Medicine today regeneration-repair.ed.ac.uk/promising-ne...

Did you ever wonder about the role of oligodendrocytes in Parkinson's disease? Check out our new unsolved mysteries article in collaboration with the Burbulla lab! It is quite certain that a lot of work moves in this direction. journals.plos.org/plosbiology/...

Happy new year and happy reading of our new review on cerebral small vessel disease! Joint effort with Ronja Kremer and Joanna Wardlaw! www.nature.com/articles/s41...

So happy to see this work published! This is still the biggest single nuclei dataset of MS, and poses some fascinating questions. We found that the proportions of cell types across lesion types varied as expected, e.g. in active lesions we saw fewer oligos and more microglia.

Positive #MS research news just before Christmas! A team co-led by @annawilliamslab.bsky.social has published gene expression findings from post-mortem samples that separates MS brain samples into 4 groups. Paves the way for personalised treatments. More at www.annerowlingclinic.org/about/news/m...

9th Day of Research: £9million to support the next generation of dementia researchers🧑‍🎓 The investment from @alzheimerssoc will help the IRR support and nurture dementia researchers at the start of their career. 📰 Read more: edin.ac/48KD4g6 #12DaysOfResearch #CRM

Transcription factors find and activate their target genes by recognising how DNA is packaged inside the nucleus of cells. New research from Dr Abdenour Soufi & colleagues published in Nature. #RegenerativeMedicine #CRM regeneration-repair.ed.ac.uk/news/irr-new...

I wrote an article about my dad's death, and how it affected my views on assisted dying, published in the Times Free version here

The Myelin Network meeting in Kassel was simply terrific! Thanks to the organisers @myelincentric.bsky.social @axoglia.bsky.social @Tanya Kuhlmann. Exciting science and excellent socialising.

Very excited to present part of my spatial lipidomics project using MALDI-FT/ICR technology today at the CMVM Postdoctoral Symposium, University of Edinburgh. A great opportunity for catching up with colleagues. Special thanks to the organizers, career panelists and sponsors for the invitation.

My first first author paper is out! doi.org/10.3390/gene... Main message: 💸 Less expensive sequencing methods can provide just as good quality single-cell data 📊 With David A. D. Munro, Meryam Beniazza, Josef Priller, @annawilliamslab.bsky.social, Andrea Corisnotti

The Williams lab is on a roll. @nadinebc.bsky.social has her first first author paper reviewing sequencing methods for single-cell data. As said by Nadine 'Less expensive sequencing methods can provide just as good quality single-cell data' Check it out for an interesting read! 📢

A new News & Views article from our lab @annawilliamslab.bsky.social is out today highlighting some major advances in understanding MS using spatial transcriptomics. A great lunchtime read from @kellie-horan.bsky.social 📖📊 www.nature.com/articles/s41...

The directors of the new Alzheimer’s society VIDA PhD programme in vascular and immune interactions in dementia together at the beginning of the adventure! Thank you ⁦‪@alzheimerssoc‬⁩ for the start up meeting!

Profs Anna Williams and Tilo Kunath are appointed as co-directors of the University of Edinburgh centre for regenerative medicine!

Our new snRNAseq paper on glia in Huntington’s disease is now out! eur02.safelinks.protection.outlook.com?url=https%3A...