Researchers at KI and @yale.edu have created a multidimensional, molecular map of how the mouse #brain develops after birth and how it reacts to #inflammation. The study is published in @nature.com. 🧪 #neuroscience news.ki.se/scientists-m...

Researchers @ki.se and Yale University have created a multidimensional, molecular map of how the mouse #brain develops after birth and how it reacts to #inflammation #research supported by Knut and Alice Wallenberg Foundation #MS #neuroscience @gocastelobranco.bsky.social news.ki.se/scientists-m...

Latest from the lab in colab with @rongfan8.bsky.social

Låter som något äkta gnällisar skulle säga.

🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution. www.biorxiv.org/cgi/content/...

Our study on neuroblastoma developmental plasticity is the cover story in the latest issue of Dev. Cell @cp-devcell.bsky.social .The Chinese-ink Taiji (Yin–Yang) cover to echo cell-state transitions. Huge thanks to the editors, co-authors. #Neuroblastoma www.cell.com/developmenta...

A few weeks ago, I had to discuss about DynaTag, a smart tweak to CUT&Tag that enables single-cell transcription factor mapping with just a buffer change. Opening a number of future avenues. 📰 Via @GenomeWeb : lnkd.in/djYm_sGg #epigenetics #singlecell

Min vän Jovan har startat cykelverkstad i Gubbängens centrum cykelnomad.com. Blev en räddad palm som inflyttningspresent. Vi jobbade tillsammans för 10 år sedan och han har jobbat heltid som cykelmekaniker sen dess. Sprid gärna ordet så han kommer igång ordentligt!

Of David's countless accomplishments is the important work that Matt Porteus did in his lab on early-stage genome editing with engineered nucleases (pubmed 12730593). He and Matt both speak about this in the documentary "Human Nature." A true titan. www.nytimes.com/2025/09/07/s...

Doomscrolling pause to chat CRISPR libraries! Preprint describes our new, data-driven approach to combine on-target and off-target predictions much more intelligently for *selecting* guides, which we use to develop our newest Cas9 knockout library, Jacquere. Thread: www.biorxiv.org/content/10.1...

Our new paper on metformin, myelin, mitochondria and metabolism is now out at rdcu.be/eDbFD Thanks to Nina and all of the team!

A careful, comprehensive and creative characterization of T cell dynamics in response to pathogens, with all credits going to @rohamparsa.bsky.social who just opened his lab!

Excited to share our new preprint! We studied how T cells are functionally & clonally shaped across organs over time. With the new TRACK mice, we genetically label recently activated T cells with tdTomato and track their migration across tissues. #immunology #science www.biorxiv.org/content/10.1...

Träffade SR:s Mellanösternkorrespondent Cecilia Uddén och pratade om Gaza, opartisk journalistik och sorgen efter hennes kärlek Elisabet Ohlson.

Deadline (September 2) approaching! Join us and start your lab at @ki.se!

New paper from our lab! We found that LINE-1 transposons contribute to early human brain development. Funded by @asapresearch.parkinsonsroadmap.org www.cell.com/cell-genomic...

I am hiring an halftime administrative assistant for my lab! we are fun dynamic group located in Bonn DZNE. Pls Spread the word. Learn more & apply karriereamukb.de/jobs/teamass...

Tillbaka i tjänst och första texten handlar naturligtvis om RFK jr. Det är svårt att ignorera allt som han gör och förstör. (Premium, men kan läsas om man har en prenumeration på någon Bonnier-titel via Plus allt)

Join us at the FENS Single-Cell & Spatial Omics Winter School with: @sarabiz86.bsky.social @rongfan8.bsky.social @gokcegroup.bsky.social @gioelelamanno.bsky.social @sj-marzi.bsky.social @jplopez-atalaya.bsky.social Ana Falcão Florian Rosenberger Gabriel Baró Bosiljka Tasic Barbara Treutlein

The creative process in science has a set of thinking tools that we could do a better job teaching. Here are the 12 articles that Martin and I wrote about them, including "It takes two to think", "A hypothesis is a liability" and "The two languages of science". night-science.org/home/learn/r...

🧪Move over CUT&Tag, there’s a new #TranscriptionFactor mapping method in town. Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag. 🔗 Our @natcomms.nature.com paper: www.nature.com/articles/s41... 🧵Let’s break down what makes DynaTag so powerful (1/7)

1/16 New pre-print from the Sternberg Lab! We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77

Herregud vad uselt chefredaktören på DN svarar. Det är så pinsamt, så skamligt. Återigen: ingen av alla dessa medlöpare och självpåtagna censorer som bidragit till att folkmordet har fått fortgå ohejdat ska någonsin få glömma det.

12th Dev Brains: @junyuecao.bsky.social @alainchedotal.bsky.social @cecilecharrier.bsky.social @trayon.bsky.social Isabel Espinosa-Medina Beatriz Rico Michael Ziller Dwight Bergles news.ki.se/calendar/dev... @hjerling-leffler.bsky.social @ulrikakmarklund.bsky.social @flallemend.bsky.social

@carlstrom.bsky.social Clemens Ries, and Ting Sun rocking at #GLIA2025! And the launch of the Carlström lab!

Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social‬ @jasperjanssens.bsky.social‬ and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1

On now, last session of #Glia2025, and last presenter from the lab. S26 | Exploring glial diversity using single cell and spatial genomics @mrodea.bsky.social 10:00 S26-01 Multi-omic definition of astrocyte diversity in the healthy and inflamed brain

This is insane! "'Positive review only': Researchers hide AI prompts in papers" asia.nikkei.com/Business/Tec... h/t Ryan Pack

#GLIA2025 is in full swing! We’re halfway through an exciting week full of energy, ideas, and exchange. Highlights so far: 🎓 Stipend Award Session 🧠 Poster Sessions 🤝 Welcome Reception Let’s keep the momentum going! #GliologistsTogether

And for the poster session II at #EuroGlia the French Glial Cell Club is still present!

I am super happy that we have had so many visitors at the booth. #gliaRules #glia2025

What a start to #GLIA2025! We kicked off with an inspiring Opening Ceremony, our first lively Poster Session, and a warm Welcome Reception. The day ended with great conversations at the Peripheral Glia Social at The Black Stone. More to come – stay tuned!

If you're attending @gliameeting.bsky.social #glia2025 check out Lucy Ryan's talk in the trainee symposia (17) on Thursday & poster T14-001A on heterogeneity of oligodendrocyte pathology in Alzheimer's disease!

The poster session at Euroglia #Euroglia2025 #GlialCells #Neuroscience

Bruno Weber plenary lecture at #Glia2025 #FLIM The auditorium is full! ✅ Neurons can sustain activity with lactate ✅ Astrocytes become more oxidized under a ketogenic diet. ✅ Similar glucose concentrations in astrocytes and neurones ✅ Higher concentration in the ECS!

We’ve arrived in sunny Marseille and everything’s set for #GLIA2025! The Introductory Course kicked things off today — and we’re ready for an inspiring week ahead. See you soon! #GLIA2025 #GliologistsTogether

Few days to Go! #GLIA2025 is almost here! Badges ✅ Programmes ✅ Boxes ✅ The team’s in full swing behind the scenes. The final week is a whirlwind of logistics, excitement, and few ☕. 🔜 See you at GLIA2025 in Marseille! Travel safe, everyone!#GliologistsTogether

Lentivirus massively parallel reporter assays integrate & enrich for specific sequences in the genome. We utilize this to test their epigenetic modifications & open chromatin alongside their regulatory activity. Amazing work by Zicong Zhang, Fumitaka Inoue & others. www.biorxiv.org/content/10.1...

3 days left to apply – Don't miss out!

New paper 📣! Pixelgen reports its incredible new Proximity Network Assay (PNA)->3D maps of 155 proteins in single cells by sequencing by barcoded antibodies and in situ rolling circle amplification yields >40,000 spatial nodes/cell: www.biorxiv.org/content/10.1...

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Introducing Arc Institute’s first virtual cell model: STATE

Heads-up for major new faculty search at KI — with great startup packages and a wide range of subject areas.

I definitely never regretted the decision to leave New York for Stockholm and Karolinska - now you can join us: big call for assistant professors across medical disciplines coming up. news.ki.se/ki-to-recrui...

Come and join us! Start your group at Karolinska Institutet @ki.se!

Our latest work: The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis: Cell www.cell.com/cell/fulltex...

Carl Wilson, Al Jardine, Annette Funicello, Brian Wilson, Dennis Wilson, and Mike Love in The Monkey's Uncle (1965) 🖤

Rockefeller's Kivanc Birsoy is uncovering the hidden metabolic pathways that cancer cells exploit. In this Q&A, he discusses how his work could also optimize strategies for using nutrition to improve human health:

1/10 New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang's Lab! We uncover the unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: www.biorxiv.org/content/10.1...