Congrats Maria! very well deserved... @mskcancercenter.bsky.social @mskeducation.bsky.social

🎉 Congratulations to our 10 MSK Postdoc Slam finalists! 👏 You were all fantastic and it was truly inspiring to learn about the incredible and diverse work happening at @mskcancercenter.bsky.social. Our #MSKPostdocs gave the judges a real challenge… choosing winners was no easy task! 🤗 #NPAW2025

While our judges deliberate the top 3 winners of MSK Postdoc Slam, let’s celebrate our #NPAW2025 📸 contest champs! 🎉 🥇 @meganekelley.bsky.social – @agnelsfeir.bsky.social lab 🥈 Zhendong Cao – @sawyerslabmskcc.bsky.social 🥉 Manendra Lankadasari – Jones lab Congrats to our amazing #MSKPostdocs! 👏📷

It’s SHOW TIME! 🎤 Kicking off the MSK Postdoc Slam is @meganekelley.bsky.social from the @agnelsfeir.bsky.social lab, diving into how error-prone DNA repair fuels drug resistance in cancer 🧬💊

Now accepting applications for our 2026 Cancer Biology & Cancer Engineering programs. Aspiring scientists & engineers will solve fundamental problems in biology & conduct research & develop technology that will help understand, diagnose & treat cancer. bit.ly/3WUiuo1

🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀 Our new coalition advocates for sustained public support of New York’s vibrant biomedical research ecosystem — creating cures, economic gains & strengthening communities. Sign up. Stay informed. Join the movement: www.nycures.org/

We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms. Please get in touch with your CV if you are interested; closing date: 27th June 2025. More details here: candidate.hr-manager.net/ApplicationI...

Congrats!! Not a bad way to start your own lab 😜

Excited to share our latest from my postdoc at @mskcancercenter.bsky.social in the Sfeir Lab, in collaboration with the Simon Powell Lab! We uncovered a novel genome repair mechanism in human cells: RNA-templated DNA double-strand break repair (RT-DSBR). (1/5)

Here is the link to the Last Week Tonight with John Oliver about RFK, Jr, public health, and HHS (including NIH) www.youtube.com/watch?v=8H34...

My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...

Take a look at the harvard web site...We have our break-throughs and next generation drugs on full display! Come take a look at the new wonders of medicine! So proud to be a part of it!!! Harvard.edu

🚨 Join us for the @faseborg.bsky.social Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee. 📅 Abstract submission & Early Registration close on April 20, 2025! Don't miss out: events.faseb.org/event/mitoch... Please re-post!

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...

📢#BGFP25 GRANTS AVAILABLE & TALK DEADLINE EXTENDED! 💰We are excited to announce we have at least 10 reg support grants ready to award to those submitting abstracts! 🧑‍💼Our short talk submission deadline has been extended and will now close on 01 April. Submit your abstract HERE: bit.ly/3AnsVZF

Harvey Society lecture tonight features Eric Olson. Come listen to an absolute giant in muscle biology! Bonus roast/ appreciation by me and Mary Baylies! harveysociety.org/lectures/abs...

Scientists have just cured pancreatic cancer in some patients with personalized mRNA vaccines. Pancreatic cancer. And this Trump administration wants to throw it all away. They’re throwing away a cure for cancer.

A new collection of papers on #mitochondrialdiseases is ready: biomed.news/bims-mitdis/... Congratulations to all authors! @biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social Highlight: Engineering mtDNA deletions by reconstituting end joining in human mitochondria

Congrats Agnel! As a side note, also an example of how studying diverse systems of DNA repair yields unexpected benefits across domains of life, in this case the NHEJ system of mycobacteria, the first prokaryotic NHEJ system to be characterized: www.nature.com/articles/nsm...

This publication is deeply meaningful to us, as Ignas tragically passed away last year from a sudden and aggressive cancer. Proud that his incredible scientific legacy lives on through this work. We will never forget him, and it has only strengthened our dedication to the work we do at MSKCC.

No matter what Rocket Man says, the NIH offers a strong return on investment www.forbes.com/sites/michae...

Postdoc Night Science NYC! Next session is Friday 4-6pm at MSK, to learn and practice the creative scientific process! The topic this time is the import/export of ideas. Yael David join us too! @davidlabmsk.bsky.social Limited spots: docs.google.com/forms/d/12bB... @kelseymonson.bsky.social

Combining bacterial end joining with programmable nucleases, we induced mtDNA deletions in human cells at varying heteroplasmy and examined their metabolic and cellular effects. Simple tool to apply across any cell type and engineer pathogenic mtDNA deletions. www.sciencedirect.com/science/arti...

Exciting new work from Barna Lab @stanfordmedicine.bsky.social www.science.org/doi/10.1126/...

Excited to share our latest work, led by the incredible @automnenine.bsky.social (now an Ass. Prof. at Princeton)! We uncover key insights into the retrotransposition mechanisms of LINE-1 ORF2p, the enzyme responsible for writing a significant portion of our genome. www.science.org/doi/10.1126/...

How do replisomes walk on DNA? And what happens when they run into a G-quadruplex? @sahilbatra.bsky.social and @benallwein.bsky.social provide unexpected insight in our latest paper with Richard Hite @mskcancercenter.bsky.social @science.org www.science.org/doi/10.1126/.... Congrats to all authors!

REGISTRATION OPEN for @faseborg.bsky.social Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair | June 1 - 5, 2025 | Nashville, Tennessee. Apply before it is too late: events.faseb.org/event/mitoch... Please re-post!

If you are interested in mitochondria, Nashville is the place to be June 1-5. Check out this FASEB meeting. Please RT. events.faseb.org/event/mitoch...

Welcome to MSKCC!

Join us in Lisbon this July to learn how cells "Balance Genome Fidelity & Plasticity". deadline for talks extended and a # of fellowships are available to offset trainee registration. www.fusion-conferences.com/conference/1...

Huge thanks to the incredible team who made this work possible! 🙌 Check out the full preprint here: 🔗 doi.org/10.1101/2025... #GenomeInstability #DNARepair #RNA #CRISPR #DSB #Genomics @agnelsfeir.bsky.social @hinashah.bsky.social

Preprint alert

New year, new beginnings! 🎉 The Aviram Lab will officially open its doors on March 1st @mskcancercenter.bsky.social! We’ll study microbial immune systems and their connection to fundamental cellular processes like #RNA transcription and #DNA integrity. #NewPI #AcademicSky #WomenInSTEM (1/2)

Nice findings on ecDNA segregation. Congrats John and Ashley!

I Used to Run the N.I.H. Here’s What Worries Me. www.nytimes.com/2025/02/14/o...

Who knew that growing up in war-torn Lebanon—adapting to constant danger and massive uncertainty—would prepare me, 40 years later, to cope with this situation in the United States!😂😜

I am excited for this opportunity to chair the Department of Biochemistry and Biophysics at Weill Cornell Medicine! news.weill.cornell.edu/news/2025/01...

A full attack on US science means the red & blue lines will soon cross. Scientists just want science to progress to help society. This administration - and "Pres Musk" - is telling us they don't need/want US science. We will see many of our great ideas and innovation will go to China and elsewhere

⚠️DEADLINE APPROACHING ⚠️ #BGFP25 early bird and talk submission deadline closes on 30 Jan 2025! 🧬 Don't miss out on the opportunity to present at this fantastic conference in beautiful Portugal, submit your abstract now ➡️ bit.ly/3AnsVZF

Cells are filled with toxic stuff that damages healthy proteins. Is that garbage just left to rot on the curb? No way! Ubiquitin ligases have evolved to recognize chemical damage and clean it up! www.nature.com/articles/s41...

feels like the right moment to invest ... www.youtube.com/watch?v=DV6g...

🧪1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇 www.nature.com/articles/s41...

👏👏 when is ur first experiment?

🧬Short talk abstract submission for #BGFP25 is open!! 🧬 Register NOW via the conference website for a chance for a short talk opportunity! 🔗https://bit.ly/4g4XN0U

Hi Bluesky. For my first post, I'd like to advertise the latest preprint from my lab, describing at long last our reconstitution of SPO11-dependent double-strand break formation from purified recombinant proteins. Outstanding work from PhD student Zhi (Zack) Zheng.

If you are interested in pursuing a PhD in biomedical sciences in New York City, it is still time to apply to the BCMB program run jointly by Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center ! Deadline: Dec 1, 2024.

Folks in the NY area, try to attend the Harvey Lecture at 8 pm. Rockefeller University - Caspary.

The latest from our group, led by Megan Ostrowski and @martyyang.bsky.social, is now published in final form (www.cell.com/cell/fulltex...! Many thanks to our excellent peer reviewers for suggesting several experiments (including CAF-1 perturbation) to really improve the study =) #epigenetics

First post here! New paper from the lab! Profound synthetic lethality between FANCM and SMARCAL1: www.cell.com/molecular-ce...

Let's get this site started. I'm excited to share that our work on transcription-coupled DNA repair is now published! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples lesion-stalled RNA Pol II to TFIIH. 🧬🐸 ➡️ cell.com/cell/fulltex...