Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses @cp-cancercell.bsky.social www.cell.com/cancer-cell/...

You want to investigate 🧬 #mito DNA + nDNA of your favorite specimen on the #single-cell level but you have no fresh samples and only 🧊 flesh-frozen tissues? 👉 then you should definitively check out the preprint by @ms-maren.bsky.social from our lab @leifludwig.bsky.social on *Cryo-mtscATAC-seq* 🎉

To honour the #MitochondrialDisease #AwarenessWeek 💚 we bring a new collection of recently-published research papers related to mitochondrial disease: biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social Cryo-EM of the prohibitin complex

It's World Mitochondrial Disease Awareness Week 💚 Since we couldn't #LightUpForMito this year the team's looking lit in green to raise awareness instead! Read more here: www.thelilyfoundation.org.uk/charity/get-... #mitoaware #mitochondrialdisease #worldmitoweek2025 @lilyfoundation.bsky.social

Raising awareness of #mito isn't easy – it’s a complex disease that can be hard to explain 🤔 To help put mito on the map during World Mitochondrial Disease Week, our Research Manager @abioblog.bsky.social is here to explain the disease in a really simple way Watch, learn and share! 💚 #mitoaware

Years ago we discovered that missense mutations in homomeric proteins often induces their supramolecular assembly, as in the 📽️👇 - Are such aberrant assemblies of *folded* proteins toxic? Surprisingly, NO. Cells are amazingly robust systems! Paper now online @molsystbiol.org doi.org/10.1038/s443...

Replication competition drives the selective mtDNA inheritance in Drosophila ovary www.cell.com/cell-reports...

In this week's issue of mitophagy news 🪫🗑️: -Urolithin A increases healthspan via MERCS and Ca2+-mitophagy -Parkin Induces Ubiquitination and Large Extracellular Vesicle Release of HMGB1 to Activate Antitumor Immunity -a Parkin and hTau mouse cross biomed.news/bims-tofagi/...

Starting the #MitochondrialDisease Awareness Week with a new collection of papers from #week37! 📚 💚 🤍 biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social Highlights ABCA7 variants impact phosphatidylcholine and mitochondria in neurons

Did you know? Anaerobic mitochondria exist! 🧬 Many of us think of mitochondria as oxygen-dependent cellular compartments. But in certain organisms, like some algae, fungi, and protozoa, mitochondria can operate without oxygen.

Understanding cells is essential in the study of biology. Building our Simple Animal and Plant cell models make it easy to see their similarities & differences. We've also got jazzy Organelle Rings! Find out more here: buff.ly/D5GcyXA #EduSky #iteachbio #cells #animalcells #plantcells #organelles

Our new pre-print from the Greenberg and Churchman labs shows that activity-dependent modulation of RNA stability is a major, and underappreciated, mechanism of gene regulation in neurons. Tutorial below! www.biorxiv.org/content/10.1... (1/11)

A new review is online! Lin Luo, Katja Simon and colleagues @mdc-berlin.bsky.social discuss how #aging T cells cope with damaged #mitochondria -> www.embopress.org/doi/full/10....

Just finished selecting last week's novel methods for investigating the metabolome and lipidome of biological systems. biomed.news/bims-metlip/... In collaboration with @biomednews.bsky.social

Wonderful selections of papers on #MitochondrialDisease from #week35 and #week36! 📚 biomed.news/bims-mitdis/... biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social RTN4IP1 required for the final stages of mito CI assembly and CoQ synthesis

Good Sunday, all! After a technical glitch last week, we are back again, with TWO exciting curated selections of papers in #cancermetabolism and #mitochondrialbiology @biomednews.bsky.social. Check them here #keepreading: biomed.news/bims-camemi/... biomed.news/bims-camemi/...

For #FluorescenceFriday, microtubule networks are shown in two adipocytes 🔬 #CellBiology #Microscopy

In vivo production of CAR T cell: Opportunities and challenges "More efficient, scalable, and cost-effective alternative to conventional methods" www.sciencedirect.com/science/arti...

Please vote for my #ARTxSCIENCE2025 submission! Voting takes 10 secs renew.science/artxscience/... My image shows stem-cell derived heart cells treated with a drug that makes cardiomyocytes (pink) proliferate—without activating fibroblasts #HeartRegeneration #Microscopy #StemCells

Latest issue of curated #engineeredlivingmaterials feed: biomed.news/bims-enlima/... via @biomednews.bsky.social includes research on: protein hydrogel, bioorthogonal engineering, beaded metamaterials, synthetic cell communication & more 🧪

We love this post @biologists.bsky.social about making the menu at your next event organic and sustainable

STX4 is indispensable for mitochondrial homeostasis in skeletal muscle https://www.biorxiv.org/content/10.1101/2025.09.02.673840v1

Due to technical problem there was no selection of papers in #cancermetabolism and #mitochondrialbiology this week. I am very sorry but we will sort this out! #keepreading

Machines are scaling faster than the human capacity to govern them. The measure of leadership will be whether we build structures of trust before systems of code decide for us. Today’s AI will be embarrassingly abysmal compared to that which is to come. Most do not understand. Share this.

Protein(s): IRG1/ACOD1 + TCA cycle enzymes Function: Anti-microbial activity & immunomodulation. Behaviour: Release of mitochondrial nucleic acids (DAMPs) during infection, which synergise with PAMPs to regulate innate immune response. #Immunometabolism #mitochondria

Has summer writing reminded you how much you actually like writing? Are you worried you’ll lose that connection again when teaching starts? The FREE 15-Minute Writing Challenge might help you figure out how to keep things going. jovanevery.co.uk/15-min-writi...

They guard apoptosis. 🤍💚 When I first started studying mitochondria, I saw them mainly as ancient endosymbionts - keepers of oxidative phosphorylation, the TCA cycle, and population history through mtDNA. But the deeper I went, the more I realized: mitochondria are everywhere in cell biology.

Last two weeks of literature relevant for #MitochondrialDisease! 📚 @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social Please browse the collections here! 👇 biomed.news/bims-mitdis/... biomed.news/bims-mitdis/...

Scientists created a strong, highly porous solid that can clean up oil spills using sustainable and reusable materials. New video by Erin Faye Dizon! #SciComm #SciNews www.tiktok.com/@sciworthy.c...

🍹Zhang, Chang et al. identify the protein TMEM65 as the #mitochondria Na+/Ca2+ exchanger, showing that it dimerizes to mediate ion transport and contains a binding site for a well-known inhibitor of mitochondrial Na+/Ca2+ exchange. 👉https://rdcu.be/eAN3r bit.ly/3UtNlag

Thanks to Yanwei Su from @volkerhaucke-lab.bsky.social, we have a new scientific image of the month: When morphology gets romantic 🫶- this is a U2OS cell overexpressing Sec61b (ER), stained with LAMP1 (lysosome) and DAPI (nuclei), to test lysosome–ER membrane contact sites.

From Lab to Launch 🚀 #HelmholtzMunich joins Deep Science Ventures & SPRIND to support the Venture Science Doctorate – a new PhD program merging #science & #entrepreneurship. 👉 Read more: t1p.de/z4r0y 👉 Apply now: t1p.de/hpm7r @sprind-en.bsky.social @helmholtz.de #PhD2026 #VentureScienceDoctorate

📢Last weeks #immunometabolism discoveries @biomednews.bsky.social ⬇️⬇️⬇️ biomed.news/bims-imicid/... Highlights: I) Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control - cell.com/cell-metabol...

#MitochondrialDisease collection of papers from #week32! 📚 biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social Highlights Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson's disease

Good Sunday all. A wonderful selection of papers in #cancermetabolism and #mitochondrialbiology is waiting for you. Check it here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading "Our plans never turn out as tasty as reality."-Ram Dass

Excited to share our new preprint, led by Kirandeep Deol! 🤩 Genetic screens uncover mechanisms regulating FSP1 abundance in cancer. Vitamin B2 metabolism promotes FSP1 stability via FAD synth / binding, further linking nutrient metabolism to ferroptosis. www.biorxiv.org/content/10.1...

Wonderful selection of papers on #MitochondrialDisease from #week31! biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social A few highlights below, many more inside! www.nature.com/articles/s42...

Kerry & Jelle discuss developing gene therapies for mitochondrial disease — in collaboration with labs around the world! - Watch the Video bit.ly/3UCF0kC 🌍Sign up to IMPACT to let your voice be heard bit.ly/4ohHhiN

Our work on new paradigm in peroxisome biogenesis and PEX39 (1st human peroxisomal biogenesis protein (peroxin/PEX) found in > 20 yr) is out in @natcellbio.nature.com! Equal collab w/Tony Rodrigues (Jorge Azevedo lab), @dwendscheck.bsky.social (Bettina Warscheid lab) www.nature.com/articles/s41...

🔊Last weeks #immunometabolism findings @biomednews.bsky.social ⬇️⬇️⬇️ biomed.news/bims-imicid/... A large & varied collection this week (1/n) The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment sciencedirect.com/science/arti...

Here it is❗️Our updated inventory of genes required for #OXPHOS & findings on #mito defects in #Menieres is now out at Cell Reports by Cell Press! 🎉   Thank you to all of our collaborators and funding sources, this was a great and exciting project from start to finish. 💫 www.cell.com/cell-reports...

Out now: rdcu.be/evxCv We've used CoQ10 headgroup intermediates to treat mouse models of a mitochondrial disease and improve the neurological symptoms of a patient with this disease. Grateful for funding from @damonrunyon.org , Pershing Square Foundation, @americancancersoc.bsky.social, NIH!

Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming. 🙏 @biomednews.bsky.social Enjoy and share 😊 biomed.news/bims-meract/...

Below is the link to another week of #mitophagy papers! 🔋🗑️ biomed.news/bims-tofagi/... Thanks to @biomednews.bsky.social for pre-sorting. This week's highlight: PNPLA7 is required for the Parkin-dependent mitophagy shut-down that leads to mitochondrial accumulation in adipose tissue browning

#Throwback 🧪 REVIEW | Mitophagy in human health, ageing and disease L Ferrucci, D D’Amico et al

Latest weekly digest is out! 🗓️ July 27edition — featuring the latest in metabolomics and lipidomics. If you’re an analytical chemist or want to learn about small molecule analysis, this one’s for you. 📖 Read the digest: biomed.news/bims-metlip/... #metabolomics #lipidomics #massspec #protocols

Kicking off the lab BlueSky with this picture of a happy hairy growing #axon! Looking forward to connecting with science chats and to growing research ideas 🧠🔬✨

This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: PERK and IRE1α promote exosome secretion via blocking lysosomal degradation of multiple vesicular body #JBC www.jbc.org/article/S002...

Good Sunday all. A beautiful selection of papers in #cancermetabolism and #mitochondrialbiology is ready for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading "If your eyes are blinded with your worries, you cannot see the beauty of the sunset." - Jiddu Krishnamurti

#MitochondrialDisease collection of papers from #week30! 📚 biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease | New England Journal of Medicine www.nejm.org/doi/10.1056/...