Department of Immunobiology at UNIL (@dib-unil.bsky.social)

The TLR7/9 adaptors TASL and TASL2 mediate IRF5-dependent antiviral responses and autoimmunity in mouse - Nature Communications TASL is an adaptor molecule bridging Toll-like receptor signalling and transcription activation by IRF5. Here the authors show that TASL deficiency impacts TLR7/9 responses, and that a TASL paralogue,... https://www.nature.com/articles/s41467-024-55692-y