📣 Reminder 📣 There is still time to apply for this #job #opportunity in the field of #metabolic #diseases at the Department of Biomedical Sciences @fbm-unil.bsky.social @unil.bsky.social 👇👇👇

Paper(s) alert from our RESOLUTE project – In a compilation of four papers in @molsystbiol.org we show how we were deciphering cellular logistics and present a comprehensive systematic blueprint of chemical transport pathways with #SoluteCarrier transporters

🚨 Abstract submission deadline: July 15th 2025🚨 Do not miss the opportunity to present your research: 10 selected short talks and an exciting poster session! Register and submit your abstract here: wp.unil.ch/immunobiolog...

Big congratulations to Cyrielle Hou (@dib-unil.bsky.social @fbm-unil.bsky.social) for receiving the Young Investigator Award at the 13th Meeting of the International Society of Systemic Autoinflammatory Diseases (ISSAID) in Paris! 🏆👏 And kudos to the organizers for a fantastic conference!

The whole DIB would like to congratulate Pascal Schneider for his Lifetime Achievement Award! More info: www.unil.ch/news/1749042...

We're looking forward to taking part in this meeting this October! JEM's Deputy Editor Gaia Trincucci (@gaiajexpmed.bsky.social‬) will be there – be sure to connect with Gaia to discuss your research and learn about publication 🔬💻✍️📄 #InnateImmunity #Immunobiology

🌿 Bravo aux 12 laboratoires certifiés LEAF @fbm-unil.bsky.social 👏 Arber Lab, Bagni Lab, Chatton Lab, Du Pasquier Lab, Jourdain Lab, LPA, M-Lab, Martinon Lab, Rebsamen Lab, Suter Lab, Thome Lab, Widmann Lab. ➡️ www.unil.ch/news/1747834... #LEAF #recherche #durable

Register for this exciting meeting on Innate Immunity coming up in Switzerland! 🇨🇭

Interested in #InnateImmunity ? Register now to secure your spot — abstracts can be submitted later! More info: wp.unil.ch/immunobiolog... #ImmunoSky

Research Highlight ✨|TASL has a key role in SLE Read the original articles: bit.ly/3XLPzUm and bit.ly/41FilqV 📖 @rebsamenlab.bsky.social @dib-unil.bsky.social

🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!

What do Pablo Picasso and Charles Janeway have in common? Both were interested in patterns of life. Janeway was focused on pathogen associated molecular patterns (PAMPs) that are detected by our immune system. But what are these patterns he refers to?

Delighted to see our latest paper selected as “Research Highlight” by @natrevrheumatol.bsky.social ! Original study @naturecomms.bsky.social : rdcu.be/d7lK5 #lupus #innateimmunity #autoimmunity #ImmunoSky

🚨Registrations are open🚨 Join us in Lausanne Switzerland October 1-2 for an exciting symposium on innate immunity with oustanding invited speakers, short talks selected from submitted abstracts and poster sessions. Attendance is limited to 150 participants!

I'm really excited to join the University of Geneva as associate professor. I look forward to expanding our research program in systems immunology within the Department of Pathology and Immunology and contributing to advance the Faculty's data science capabilities! JOB OPPORTUNITY👇

#Macrophages literally eat and live of dead #bacteria, while live bacteria stimulate inflammation. 🦠 viability is sensed by an mTORC1 metabolic switch. Superb tour-de-force study @nature.com by the Garaude lab in Bordeaux, with help from @sanderlab.bsky.social www.nature.com/articles/s41...

Chaque franc investi par @etatdevaud.bsky.social dans @unil.bsky.social en génère 4,7 dans le canton www.vd.ch/actualites/c...

No added sugar: CCDC134 stabilizes ER chaperone Gp96 for TLR biogenesis. Leslie Domínguez Cadena and Antje Blumenthal discuss new study from @lbernaleau.bsky.social et al. @@rebsamenlab.bsky.social (https://buff.ly/3ZrE70d) in Insights: https://buff.ly/4gwjt5N

💡 At a joint press conference, the #SNSF and its ERI partners called on the Federal Council to abandon the planned cuts to #education, #research and #innovation in the "relief package 27", as they would have far-reaching consequences for the #economy and society. ➡️ https://buff.ly/3CTR2AM

Check out the Insights piece from A Blumenthal & L Dominguez Cadena on our discovery of CCDC134’s role in Gp96 stability and TLR biogenesis. Many thanks to the authors for discussing our work broadly, integrating recent studies by Rohatgi and Locher/Kaelin labs, and highlighting key open questions.

This report investigates the effect of 21 variants in the hSLC39A8 gene experimentally on protein expression, localization, and uptake of metal ions, and computationally on dimerization stability RESOLUTE and REsolution the @supertifurgalab.bsky.social at CeMM https://buff.ly/4aHOzG3

Thrilled to see our recent paper on CCDC134 highlighted in @jem.org ! Grateful for the opportunity to contribute to this field and engage in meaningful discussions!

New preprint from the lab! 🚨 🧫 New galactose #CRISPR screening strategy 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂Mito defects in #Menieres disease by @marcellharhai.bsky.social @fbm-unil.bsky.social A short thread 1/5 www.biorxiv.org/content/10.1...

We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky

I’m thrilled to share our latest work from the @rebsamenlab.bsky.social, now published in @naturecomms.bsky.social! For the first time, we reveal the importance of the SLC15A4-TASL-IRF5 pathway in vivo. It was a great pleasure to contribute to this project!

Excited to share our latest paper out today in @naturecomms.bsky.social ! Great work led by postdoc Ales Drobek showing for the first time the critical role in vivo of the SLC15A4/TASL/IRF5 pathway that we discovered few years ago. #ImmunoSky #InterferoSky

🎓 The PhD program in Cancer and Immunology in Lausanne is accepting applications! If you're passionate about advancing research in cancer or immunology, we want to hear from you! 🌟 #PhD #CancerResearch #Immunology www.unil.ch/cancer-immun...

New: Bernaleau et al. @rebsamenlab.bsky.social use a loss-of-function genetic screen to identify the ER-resident protein CCDC134 as an essential regulator of Toll-like receptor (TLR) responses. CCDC134 binds and stabilizes the TLR chaperone Gp96. https://buff.ly/3ZrE70d

Very happy to share our latest work just published in @jexpmed.bsky.social! #Firstpost rupress.org/jem/article/... Our amazing PhD student @lbernaleau.bsky.social shows that CCDC134 controls TLR biogenesis through the ER-chaperone Gp96. #ImmunoSky #innateimmunity #inflammation Quick summary here:

New manuscript by Sina Bohnacker and Julia Esser-von Bieren published in Science Immunology! www.science.org/doi/10.1126/...

Have you ever wondered whether pyroptotic corpses have functions beyond the grave? We made the surprising discovery that pyroptotic corpses are flagged by #filopodia to alert #DendriticCells they need autopsy. A short Bluetorial (1/13)👇with movies! Link: rdcu.be/d2mjm

PhD student @AndreFerdigg and colleagues report in @LSAjournal on #SLC transporters in metal toxicity. MRP1/ABCC1 protects against arsenic and mercury; SLC39A14 and SLC30A1 sensitize for cadmium; interestingly SLC30A1 modulates cadmium toxicity through zinc levels doi.org/10.26508/lsa...

The direct link to our recent pre-print FBXW7 alleviates c-MYC repression of pyruvate carboxylase to support metabolic flexibility www.biorxiv.org/content/10.1...