Veit Hornung
@v-hornung.bsky.social
📤 829
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(Innate) Immunologist at LMU Munich
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Veit Hornung
Iannacone Lab
3 months ago
Join us for this exciting meeting!
@embo.org
Workshop "Pathogen Immunity and Signalling", 8-12 June, 2026, Leiden, The Netherlands
meetings.embo.org/event/26-pat...
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Veit Hornung
Ivan Zanoni
3 months ago
#WeekendRead
!
#ToSenseOrNotToSense
!
#MysterySolved
! Berouti, Wagner, Carell,
@v-hornung.bsky.social
&co show
@cp-cell.bsky.social
that RNase T2 & PLDs generate
#TLR7
&
#TLR8
agonistic ligands only if RNA does not contains pseudouridines explaining avoidance of self RNA sensing!
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Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
Recognition of exogenous RNA by Toll-like receptors (TLRs) is central to pathogen defense. Using two distinct binding pockets, TLR7 and TLR8 recognize…
https://www.sciencedirect.com/science/article/pii/S0092867425006191
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Veit Hornung
Tobias Komar
5 months ago
Excited to share the first paper of my PhD, published in the Journal of Biological Chemistry. Huge thanks to all authors, especially to co-first author Stefan Bauernfried, Alex Horswill‘s lab and
@mannlab.bsky.social
, and my supervisor
@v-hornung.bsky.social
.
www.jbc.org/article/S002...
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Inflammasome-independent IL-1β activation via staphopain A protease of Staphylococcus aureus
Interleukin-1β (IL-1β) is a pivotal mediator of innate immunity, essential for orchestrating the acute inflammatory response. While the canonical activation of IL-1β involves cleavage of its inactive ...
https://www.jbc.org/article/S0021-9258%2825%2902425-1/fulltext
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Veit Hornung
Keystone Symposia
4 months ago
⏰ Deadline: Sept 17 (11:59pm MDT) Early-career scientists - submit an abstract or apply for a scholarship for
#KSAutoImmune26
: Autoimmunity & Autoinflammation 🧬 📅 Jan 19–22, 2026 | Breckenridge, CO 👉
keysym.us/KSAutoimmune26
youtu.be/nMsJANbMb-w
#KSAutoImmune26
@v-hornung.bsky.social
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Autoimmunity & Autoinflammation Meeting Promo
YouTube video by KeystoneSymposia
https://youtu.be/nMsJANbMb-w
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Veit Hornung
Pavel Kielkowski
4 months ago
The final version of our article about PLD3 AMPylation is now out
shorturl.at/iTxWx
. One protein, many proteoforms. Congratulations to Laura and thanks to
@marleenberouti.bsky.social
@v-hornung.bsky.social
@jaelab.bsky.social
@hellmichgroup.bsky.social
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Veit Hornung
Rebsamen Lab @UNIL
11 months ago
We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info:
wp.unil.ch/immunobiolog...
#ImmunoSky
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Symposium immunobiology
https://wp.unil.ch/immunobiologysymposium/
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Veit Hornung
Journal of Experimental Medicine
12 months ago
New: Sato, Miyake @UTokyo_News_en and colleagues report that the lack of RNase T2 activates TLR13, the sensor of bacterial 23S ribosomal RNAs, leading to the accumulation of tissue-protective Kupffer cells.
https://buff.ly/4hw6kL0
Companion study by
@v-hornung.bsky.social
https://buff.ly/4jG49Gy
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Veit Hornung
Waggoner Lab
12 months ago
RNase T2 plays an important role in limiting self-RNA recognition by preventing erroneous activation of TLR13
@jem.org
@v-hornung.bsky.social
doi.org/10.1084/jem....
doi.org/10.1084/jem....
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Veit Hornung
Sorek Lab
12 months ago
Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors A 🧵 1/10
www.cell.com/cell/abstrac...
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Structure-guided discovery of viral proteins that inhibit host immunity
Large-scale, structure-guided computational pipeline sifts through millions of phage proteins to identify those that bind and antagonize host immune proteins. Detected proteins are shown to inhibit no...
https://www.cell.com/cell/abstract/S0092-8674(24)01478-8
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Veit Hornung
Louis-Jeantet Foundation
12 months ago
VEIT HORNUNG
@v-hornung.bsky.social
@genecenter-lmu.bsky.social
is awarded the 2025 Collen-Jeantet Prize for Translational Medicine for his important contributions to our understanding of how foreign nucleic acids and other non-self signals trigger the innate immune system.
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Veit Hornung
Pavel Kielkowski
12 months ago
Proteoforms matter! We show how AMPylation impacts PLD3 proteolytic processing and catalytic activity. Congratulations to Laura Hoffmann and thanks to all collaborators
@jaelab.bsky.social
,
@v-hornung.bsky.social
,
@hellmichgroup.bsky.social
and Wei Xiang lab!
www.biorxiv.org/content/10.1...
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AMPylation regulates PLD3 processing
The 5’-3’ exonuclease phospholipase D3 (PLD3) is a single-pass transmembrane protein undergoing sequential post-translational modifications (PTM) by N -glycosylation, AMPylation and proteolytic cleava...
https://www.biorxiv.org/content/10.1101/2025.01.09.632087v1
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Veit Hornung
Aude Bernheim
about 1 year ago
Registration now open for the EMBO Workshop: Immune System of Bacteria !!!!
www.sisb2025.conferences-pasteur.org/home
Joins us in Institut Pasteur, Paris, April 8-10th.
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Veit Hornung
Brian Ferguson
about 1 year ago
We are recruiting an associate or full Professor of Infection and/or Immunity to the school biological sciences in Cambridge. Full details here:
www.jobs.cam.ac.uk/job/49381/
#immunology
#virology
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Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge
Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.
https://www.jobs.cam.ac.uk/job/49381/
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Veit Hornung
Gene Center Munich @LMU Munich
about 1 year ago
Don't miss this opportunity for your next career step:
add a skeleton here at some point
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📢 Postdoc opening! 📢
@soreklab.bsky.social
and we are looking for outstanding candidates for a position at the intersection of computational biology & innate immunity. Dive into impactful research in two dynamic fields. Interested? Let’s connect! 👇
www.genzentrum.uni-muenchen.de/career/postd...
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Postdoctoral Position (f/m/x) in Immunology / Biochemistry / Computational Biology - Gene Center Munich - LMU Munich
https://www.genzentrum.uni-muenchen.de/career/postdoc-immunology_sorek/index.html
about 1 year ago
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