New article from the lab on HaloTag-based chemical proteomics in RSC Chemical Biology. Simple, fast and highly selective labelling of probe-protein conjugates allow gel-based shift assay and pull-downs followed by MS proteomics. Congratulations @rubaba.bsky.social! pubs.rsc.org/en/content/a...

New preprint from the lab! Check out how to employ chloroalkane probes in chemical proteomics - in-gel shift assay and mass spectrometry. Fast, fully bioorthogonal and easy to do. Congratulation to the first author @rubaba.bsky.social! www.biorxiv.org/content/10.6...

✨ A decade of science, collaboration, and innovation – celebrating 10 years of #BayBioMS at @tum.de School of Life Sciences! What an incredible day at the 10-Year Anniversary Symposium 🎉

One gene can code for proteoforms with: ◼️ different functions ◼️ different sequences ◼️ different regulation ◼️ different cell type expression Such examples should inform the interpretation of gene deletion experiments seeking to infer "gene functions".

For those who like this work: There are still 2 weeks left to apply for the PhD position in my group! www.chemzymes.com

I am looking for a PhD student interested in enzymes! For the full annoucement: www.chemzymes.com

What can HaloTag do for you? Triggered fluorogenic labelling? Molecular recording? Photo-Chemically Induced Dimerisation? Philipp Mauker's CHalo motif lets reagents do all three, and more. Read the preprint here - doi.org/10.1101/2025... #chembio #fluorescence #cellbio #SLP

The final version of our article about PLD3 AMPylation is now out shorturl.at/iTxWx. One protein, many proteoforms. Congratulations to Laura and thanks to @marleenberouti.bsky.social @v-hornung.bsky.social @jaelab.bsky.social @hellmichgroup.bsky.social

New paper in great collaboration with @cardosolab.bsky.social on Super-Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation published in Advanced Science: doi.org/10.1002/advs... @iocbprague.bsky.social

LMU remains the best German university www.lmu.de/en/newsroom/...

We are hiring! If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland! More information on www.epfl.ch/labs/gr-schu...

Great talk by Ronald Micura about Challenges in biological RNA chemistry @lmumuenchen.bsky.social 😀

I am very excited to share the second paper of my PhD published in @cp-cell.bsky.social. Many thanks to all co-authors, especially from Thomas Carell's group, and my supervisor @v-hornung.bsky.social for their great support and collaboration! www.cell.com/cell/fulltex...

Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry. 🙏 RETWEET (We want to recruit internationally) Organic chemistry meets #DirectedEvolution Highly interdisciplinary & passionate research group uni-bielefeld.hr4you.org/job/view/433...

🎉 Nadace Experientia zná stipendisty pro rok 2025! 👨‍🔬 Jakub Copko z @iocbprague.bsky.social díky stipendiu ve výši 1 060 000 Kč vycestuje na University of Göttingen. 👨‍🔬 Lukáš Janecký z @iocbprague.bsky.social získal stipendium ve výši 1 215 000 Kč a zamíří na Stockholm University. Gratulujeme!

🚀 PhD position at the intersection of medicinal chemistry and chemical biology. You'll develop ferroptosis inhibitors to combat bacterial lung infections 🧪 Research (50%) /🎓 Teaching (50%) Looking for someone with: ➡️ Strong background in organic synthesis ➡️ Passion for working across disciplines

One algorithm to rule them all? CHIMERYS bridges the gap — DDA,DIA and PRM — together at last! With #CHIMERYS, we can now directly compare DDA and DIA data — 🍎 to 🍎 finally made possible. doi.org/10.1038/s41592-025-02663-w #KusterLab #WilhelmLab #MSAID #Proteomics

Come join our team! We have an opening for a research associate ("Ratsstelle"). Expertise in nucleotide chemistry and LC-MS is required. 👉 job-portal.lmu.de/jobposting/b... Deadline for application is June 01, 2025.

Back in July 2023 we organized a small bioML symposium at @iocbprague.bsky.social, and it turned out to be a very pleasant and successful event. This summer we are following up with a great line-up of speakers. Please register for free, deadline May 30. tinyurl.com/bioMLPrague25

Great to see the new concept of protein PTMs functionalization published in @chemicalscience.rsc.org! The GlyTACs enable selective degradation of glycoproteins in living cells. Congratulation to Haoyu and Liu. Have a look on the full story here: pubs.rsc.org/en/Content/A... #chembio

We are happy to announce the new team that will organize the Virtual ChemBioTalks from this edition onwards Marina Rubini @mlakemeyer.bsky.social @michellefrei17.bsky.social Hana Macíčková Cahová @drglycoben.bsky.social @borisvauzeilles.bsky.social @stephanhacker2.bsky.social (1/4) #ChemBio #ChemSky

The flash talk session and the posters were a highlight of #ABPP2025. We heard a lot of exciting research into #covalent #fragment screening, #antibiotic development, #microbiome activities, posttranslational modifications #PTMs and lysine-directed #kinase inhibitors. #ABPP #ChemSky #ChemBio

The first chemistry.unwrapped video in the ENERGY series is out 💥🔥 Watch on YouTube in full quality: www.youtube.com/watch?v=OdPT... @chemistryunwrapped.bsky.social @juriceklab.bsky.social #ChemSky #PiSky

#research #chirality Stereoanalysis of the Antiparasitic Natural Product Callunene and Its Synthetic Intermediates (Ferenczei, Perlíková) - JNP @acs.org: pubs.acs.org/doi/10.1021/... @iocbprague.bsky.social #UCTPrague @czechacademy.bsky.social

Our newest paper on enzymatic synthesis of hypermodified zwitterionic DNA bearing 4 different cationic groups has just been published in NAR. doi.org/10.1093/nar/...

We are looking for PhD candidates to work in Paris at @sorbonne-universite.fr on synthesis & (photo)catalysis inside cyclodextrins with bimetallic complexes in collaboration with @metallacycle.bsky.social

🥳Congratulations, Matthias Tschöp! 🥂 Following our successful past collaborations in promoting young PIs to tenure-track professorships, we look forward to working with you to shape LMU’s future🤩

Bei ihr trifft Fachwissen auf didaktische Kompetenz: Die Studierenden von Prof. Dr. Lena Daumann @daumannl.bsky.social aus der Chemie @hhu.de sind begeistert und haben sie für den #hhuLehrpreis2025 nominiert. 🧪

‼️PhD Position in Chemical Biology at the University Antwerp‼️#chembio ✔️Deadline: ‼️February 20, 2025‼️ ✔️Find full details and submit your application here: www.uantwerpen.be/en/jobs/vaca...

Superb! Welcome.

Thank you Stephan! Great to be here and discuss the #chembio

Proteoforms matter! We show how AMPylation impacts PLD3 proteolytic processing and catalytic activity. Congratulations to Laura Hoffmann and thanks to all collaborators @jaelab.bsky.social, @v-hornung.bsky.social, @hellmichgroup.bsky.social and Wei Xiang lab! www.biorxiv.org/content/10.1...

Post-translational modifications on proteins can serve as metabolic anchors to target selected proteins for degradation. We are excited to share our study on GlyTACs, a PROTAC modality targeting glycoproteins for proteosomal degradation. Check it out #chembio! chemrxiv.org/engage/chemr...

i cobbled together a science starter pack: Neuronal Post-transcriptional / Protein Synthesis agonizingly incomplete - join our growing community! go.bsky.app/Qqq9HTw

Reflecting on 20 years of progress Sarah E. O’Connor, Benjamin F. Cravatt and Chengqi Yi talk about the major changes in chemical biology, the advances that have most affected their research, and their thoughts about the important questions facing chemical biologists. rdcu.be/d5Sm0

Hay @carolynbertozzi.bskyverified.social ! I am bit slow to make the jump to @bsky.app. Now I need to figure out how to get a good feed going! Maybe if you follow me people will see my posts! Glad to be here!

Job alert: fully funded postdoc position in chemical biology in beautiful Geneva! Do you have a PhD in Chemical Biology or related field with organic synthetic experience? Apply now! Details on how to apply can be found here: www.hoogendoornlab.org/joinus #chemsky #ChemBio

Big thanks to Haoyu for his determination to uncover formation of aryl radicals from aryl pinacol boronates using ammonium persulfate or dimethylacetamid to react spontaneously with proteins and in particular disulfide bonds between peptides. No metal catalysis or photoinduction in aqueous buffer.

Hello #chemicalbiology community on bluesky! Some of you may know my lab. We work on covalent chemical probes with a main focus on proteases. #abpp #chemicalproteomics You can visit www.verhelstlab.net or check our papers on pubmed.

📯📯 Chemical Biology starter pack 📯📯 140 PIs & groups posting primary research in chemical biology. Please reskeet (?) & reply to this post if you want to be added! go.bsky.app/KLrTWoj Let's make ChemBioSky even greater again! #realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange

Chemoproteomics starter pack, thanks mostly to @stephanhacker2.bsky.social's strong network go.bsky.app/JKJ1ZHt

Opportunity for medicinal chemist at Boehringer Ingelheim (Biberach Germany) ref: 13873 | closing 18-Aug-2024 #MedChem #EUChemJobs #ChemJobs #chemsky 🧪 jobs.boehringer-ingelheim.com/job/Biberach...

EMBO Chemical Biology conference, join us in Heidelberg in September! Running since 2008, great event to learn about newest developments and to network. www.embl.org/about/info/c...

We have a PhD position available in my group. The exact topic will be tailored to the applicant, so don't hesitate to apply if you are interested in the synthesis of Covalent Organic Frameworks (COFs). #chemsky #chemjobs

Do you have experience in #nanotechnology #nanoscience or #organicChemistry but looking for a non-research career path? Want to contribute to a more equitable and sustainable scholarly communication system? Please share! www.beilstein-institut.de/en/about-us/... #diamondOpenAccess #chemjobs #chemsky

If you are interested to learn about our research towards new targets for the antibiotics of the future, check out my eye-opener video. Thanks to the Leiden Institute of Chemistry, the Faculty of Science and the KNCV for making this possible. www.eye-openers.nl/en/seethecas...

Freiburg plant scientists demand: Stand With Science and Give Genes a Chance! EU parliament: Free NGTs!

This is exactly what I and many others have been saying as well. Finding drug candidates more quickly is fine, but it just means that you're moving them up to the buzzsaw a bit faster than before.

Exciting News! Registration closing soon for our international CSHL Conference on PARP Family and ADP-ribosylation. April 3-6, 2024. Explore cutting-edge topics on PARPs in health & disease. Connect with experts, innovate & network. Register at: meetings.cshl.edu/meetings.asp...