Congratulations to newly minted Dr. Esther L. Jones @estherlj.bsky.social on her successful DPhil viva! A great collaborative project between the L. Dustin and Jelena Bezbradica @jelenalab.bsky.social labs. Many thanks to examiners Irina Udalova @udalovalab.bsky.social and Menna Clatworthy.

Excited to share that our paper examining how GM-CSF potentiates cytokine responses in human monocytes during bacterial infection is now online at the @asm.org journal Infection & Immunity! Congrats to @vvazquez.bsky.social, @mikelhaggadone.bsky.social, & co-authors! journals.asm.org/doi/full/10....

Thrilled to share our @elife.bsky.social paper "Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages" by 1st author Dr. @marisaegan.bsky.social (@cambupenn.bsky.social alum, now faculty @swarthmorecollege.bsky.social)! elifesciences.org/articles/90107 🧵(1/n)

Elegant work by @jkagan1.bsky.social and team on identifying how innate immune receptor Caspase 11 recognises molecular patterns in LPS and self lipids.

#InterferonFriendOrFoe?! Klein @kahlenberglab.bsky.social &co show Science Immunology that UV drives mitochondrial Z-DNA to induce type I & III IFNs in keratinocytes. IFN-I upregulates ZBP1 that binds Z-DNA activating cGAS-STING to boost IFNs, photosensitivity & inflammation in #Lupus skin!

The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells. www.science.org/doi/10.1126/...

We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky

Two weeks to go until the application deadline for ILESLA. If you or anyone you know would benefit from full funding to carry out a PhD in Life and/or Environmental Science please visit/refer to our website page iles.web.ox.ac.uk/how-apply where you can see open day videos and get full guidance.

Absolutely fantastic work by Vivian Lau and @gerardlab.bsky.social on IFNy-related tumour escape! Must-read for all tumour immunologists! 💯

Ok, let's start here on @bsky.app by reposting this truly outstanding paper by @lozanzi.bsky.social and colleagues!