We built a targeted protein degradation–based system to mimic reproductive age-related aneuploidy in young eggs - revealing how chromosome errors associated with female infertility arise with age. 🧬✨ With @jiyeonleem.bsky.social and our team at Yale MCDB. Read: www.nature.com/articles/s43...

We hire! The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities. More details here: cytomorpholab.com/index.php/jo...

Some good news during these difficult times. Please check out our new preprint. We built a new tool to probe the origins of high oocyte aneuploidy rates at advanced female reproductive ages. This NIH funded work was led by a fantastic postdoc in the lab, Jiyeon Leem. www.biorxiv.org/content/10.1...

Sharing some oocyte spindle love-an image taken by PhD student Phia Maddocks. This beautiful work is supported by our NIH funding. Without this funding, we cannot understand the complexities of fertility genetics. With declining fertility rates, this work is essential to human health.

This is couple of years old since I rarely have time to sit at a scope these days but I was inspired by the end of year #FluorescenceFriday posts on hear and thought I should drop on y’all my Eye of Sauron, aka a mouse oocyte containing nuclear actin filaments #actin #meiosis #oocytes

Happy to see this out before the end of the year. Fantastic work by Lily Wang with help from our wonderful technologists in the Discovery Platform Proteomics Core managed by Christos Spanos. Great publishing experience @embojournal.bsky.social www.embopress.org/doi/full/10....

Chromosome segregation errors are common in the early stages of human embryonic development. Read here our open access commentary on three recent studies of spindle architecture and positioning features that could provide insights into why early embryos are predisposed to aneuploidy. rdcu.be/d1TgG

My lab came as me for Halloween…i’m proud 🥹

Yale University and the Department of Molecular, Cellular and Developmental Biology is looking for Assistant Professor in Plant Biology and Assistant Professor in Systems Biology. #neurojobs #neuroscience l🧪l🧠📊l🧠🖥️ #academicsky #statsky #physics mcdb.yale.edu

The Department of Molecular, Cellular and Developmental Biology at Yale University is looking for a Tenure-track Assistant Professor in Plant Biology mcdb.yale.edu PDF: mcdb.yale.edu/sites/defaul... #PlantSciJobs FEED for Plant Science Jobs here: bsky.app/profile/did:...

Come be my colleague! The MCB Department at UConn is looking for a TT Assistant Professor in the broad fields of structural biology, biophysics, and biochemistry. Collaborative department, strong graduate program, and state of the art core facilities. academicjobsonline.org/ajo/jobs/25945

Excited to host @binyammogessie.bsky.social at UConn MCB tomorrow! Looking forward to nerding out about eggs and chromosomes 🧬🔬🥚