What an egg-cellent Sunday for oocyte papers! This week we have even TWO highlights: pubmed.ncbi.nlm.nih.gov/41188464/ by T. Kitajima and pubmed.ncbi.nlm.nih.gov/41184483/ by @binyammogessie.bsky.social Read the full issue here: biomed.news/bims-cebooc/... #cebooc @biomednews.bsky.social

Good Sunday, all. The weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology is out, a concentrate of groundbreaking discoveries: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading "There are years that ask questions and years that answer."-Zora Neale Hurston

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT | Science www.science.org/doi/10.1126/... Great work from @rjdlab.bsky.social !!

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis: Molecular Cell www.cell.com/molecular-ce...

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis: Molecular Cell www.cell.com/molecular-ce...

As a mindfulness advocate, it is important to stress that meditation can have downsides if approached carelessly. It’s crucial to prepare and practice moderation. If meditation causes distress, that’s okay! Adjust your approach to your mindfulness journey. journals.sagepub.com/doi/10.1177/...

www.nature.com/articles/s41... Lymph node environment drives FSP1 targetability in metastasizing melanoma

www.nature.com/articles/s41... Secretome translation shaped by lysosomes and lunapark-marked ER junctions

Following a recent article about the different layers of conceptualisation in a science project, this is about a pet peeve of mine. I would love to hear your views. network.febs.org/posts/thinki...

Wonderful work from @mito-oncogene.bsky.social and @edreznik.bsky.social on the role of mito ribosomal RNA in cancer.

Good Sunday, mitolovers. Here is a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading "Coming back to where you started is not the same as never leaving."-Terry Pratchett

Glutamine synthetase deficiency enhances CD8 T cell survival and stress resilience in the tumor microenvironment url: academic.oup.com/jimmunol/art...

The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts: Cell Reports www.cell.com/cell-reports...

Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cyclehttps:// www.sciencedirect.com/science/article/abs/pii/S1097276525008196 Congratulations @bensahralab.bsky.social !!

Good Sunday, all! Here is an exciting selection of papers in #cancermetabolism and #mitochondrialbiology: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading "Inside us there is something that has no name, that something is what we are."-José Saramago

open.spotify.com/track/7IoK6j... Oldie but goldie.

Thank you Alzforum for featuring our new preprint identifying regulators of disease states of #microglia. Project led by Amanda McQuade, computation by Reet Mishra, collaboration with the Nunez and De Jager labs. Alzforum www.alzforum.org/news/researc... Preprint www.biorxiv.org/content/10.1...

www.sciencedirect.com/science/arti... Organellar pH as an emerging vulnerability to exploit in cancer Congrats to @cosimocommisso.bsky.social

new out in Nature www.nature.com/articles/d41...

Targeting SARM1: from inhibition for neuroprotection to activation for neuroablation: Trends in Pharmacological Sciences www.cell.com/trends/pharm...

We asked 3,785 PhD students across 107 countries about their experiences. Where do you think the happiest doctoral candidates were? go.nature.com/3Wzz2lL

What if the DNA methylation enzyme DNMT1 isn’t just about DNA? Our new preprint reveals a cytosolic role for DNMT1 as a scaffold controlling neuronal morphology via DOCK7–Rac1/STMN1 signaling & mitochondrial trafficking. A paradigm shift in DNMT1 biology! www.biorxiv.org/content/10.1...

Good Sunday, mitolovers! 🌟 Exciting news in the world of #cancermetabolism and #mitochondrialbiology! 🧬 Check out the papers from last week here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading📚 "Knowledge is an unending adventure at the edge of uncertainty."-Jacob Bronowski

An updated preprint now includes segmented bioenergetic assessment of human kidney samples from rejected transplants or non-tumor resection. This methodological breakthrough allows for a highly-adaptable, rapid, and non-genetic means to separate heterogeneous tissues to profile OXPHOS.

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

Excited to share that we are hiring a research assistant for my lab at UTSW in Dallas (www.nils-burger-lab.com). Please share with your mentees. utsw.taleo.net/careersectio... We are also looking for motivated, curious, and enthusiastic postdoctoral fellows!

This week on the Nature Careers Podcast: How having too rigid a plan could result in exciting opportunities passing you by. go.nature.com/3WHgwYs

Aged mice exhibit widespread metabolic changes but preserved major fluxes: Cell Metabolism www.cell.com/cell-metabol...

TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors: Cancer Cell www.cell.com/cancer-cell/...

Aged mice exhibit widespread metabolic changes but preserved major fluxes: Cell Metabolism www.cell.com/cell-metabol...

HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics: Cell www.cell.com/cell/fulltex...

www.nature.com/articles/s41... Spatial metabolic gradients in the liver and small intestine

www.nature.com/articles/s42... Mitochondrial and psychosocial stress-related regulation of FGF21 in humans

MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death www.nature.com/articles/s41... congrats @mitodynamics.bsky.social & team!!

www.biorxiv.org/content/10.1... very cool work and a massive effort from Sanju Sinha lab

#Autophagy and #mTOR paper published last week, lots of cool stuff, enjoy! biomed.news/bims-auttor/...

Creatine fuels cancer. In @asbmbjournals.bsky.social we show CKB drives CK activity in NSCLC, osteosarcoma & ovarian cancer, promoting metastasis & anoikis resistance. Led by postdoc Mouna Tlili, in collaboration with Peter Siegel + @mcgillgci.bsky.social. Preproof: www.jbc.org/article/S002...

Fresh selection of papers on #MitochondrialDisease from #week41! 📚 💚 biomed.news/bims-mitdis/... @biomednews.bsky.social @mitoscientist.bsky.social @gavinmcstay.bsky.social Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations www.science.org/doi/10.1126/...

This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: A genome-to-proteome map reveals how natural variants drive proteome diversity and shape fitnes www.science.org/doi/10.1126/...

My little book on Schrödinger's famous classic 'What Is Life?' is out! Offering the most comprehensive analysis ever undertaken of the book's origins, reception, impact, and legacy, it uncovers Schrödinger's motivations in writing it, and shows how it has shaped our current understanding of the cell

Good Sunday, all. Your weekly curated summary of papers in #cancermetabolism and #mitochondrialbiology is ready, don't miss it as it is full of exceptional discoveries: biomed.news/bims-camemi/... Biomed News #keepreading "To see takes time, like to have a friend takes time." -Georgia O'Keeffe

open.spotify.com/track/37Ylwk... Highly recommend musician. What a music genius!

www.sciencedirect.com/science/arti... ... and congratulations to Kivanc Birsoy and his team too

www.sciencedirect.com/science/arti... Congratulations to Thomas MacVicar & team!

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging | Science www.science.org/doi/10.1126/...

The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...

I very much support this initiative by the EU inthistogether - Public Health health.ec.europa.eu/inthistogeth...