If you want to map the spatial composition of a tissue or organ, 3D mapping is not an option. It is absolutely necessary. Due to its inherent undersampling, 2D omic mapping is almost always misleading. See details here: www.sciencedirect.com/science/arti...

The Trump admin sanctions several European officials today after Elon Musk was fined for several violations of their Digital Services Act.

Entering the USA no more… sorry for all American scientists and friends…

Announcing the #China-#France Joint #Conference on #Neurodegeneration and #Secretion, to be held on March 10-13, 2026, in #Shenzhen. Inserm #ShenzhenBayLaboratory #ambassadedefranceenchine #institutfrançais lnkd.in/eygqBe8H lnkd.in/ee88be-F lnkd.in/e__7WYTJ

Why should public or charitable funds support journals that refuse to meet basic standards of how they review papers and use publication fees? 11/11

Once a journal meets disclosure requirements, then scientists, not funders, should decide where to publish. Transparency sets the floor. Scientific judgment stays with researchers. 10/11

These requirements reduce information asymmetries, increase accountability, and let scientists make informed publishing choices. Funders should use their leverage to force transparency, not to rank or judge journals. 9/11

Example: Publishing in Biology (MDPI) costs ~$3,400 for profit, 17.5 day turnaround, doesn't pay reviewers Biology Open @biologists.bsky.social costs $2,500 nonprofit, ≤7 working day turnaround, pays reviewers, uses explicit rubrics and QC checks. 5/11 journals.biologists.com/bio/pages/fa...

Some funders are taking small steps. @hhmi-science.bsky.social requires preprints on servers like @openrxiv.bsky.social Others restrict use of grant funds for APCs. But these policies don't address journal quality and peer-review rigor. 3/11

Responsible use of tax dollars or charitable funds means ensuring research is published in journals that meet clear standards for rigor and transparency. This is not about prestige. It’s about quality and accountability. 2/11

Should funders mandate where grantees can publish? Probably not. But funders could mandate where grantees cannot publish. 🧵 1/11

L'Europe doit rester solide face à ces connards, parce que c'est typiquement les move de bâtards comme Musk qui vont vouloir s'en débarrasser et tous les droitos de merde. Le truc hilarant c'est l'ED française ou autre qui ne comprend pas que les US leur chie dessus pareil en ce moment.

Trump et son gouvernement vont donc lutter contre les gens qui luttent contre la haine. C'est un beau résumé de ces gros nazis.

I will be recruiting two postdocs early next year. - One image analyst - one biologist interested in working on lymphatics! Reach out if you are interested 👍

This is exactly why people claiming "it came up with a new set of experiments/ideas/concepts" are carrying water for the weasels trying to put genAI on everything. This is how we get science defunded. This is how your colleagues lose their jobs 🧪

Must say, while interviews with established PIs with deep cuts to their funding are important, the principal and longest term effects are on the trainees. An entire generation wiped of confidence.

Giving the gift of negative data 🥰 Since I joined @lsajournal.org I have handled several stellar manuscripts that report null results. These papers do very well and reviewers almost always appreciate them! Thanks @rockefeller.edu news team for the article! www.rockefeller.edu/news/38829-t...

🔥 THIS IS HUGE! Horizon is the world’s science programme, hosted by the EU. It just got bigger. Other non-European countries associated to the programme (ie paying in) include Korea, New Zealand, Canada.

Joe Strummer was my last hero. A fierce opponent of corrupt governments and parasitic corporations, he was also a sincere, gentle man who wanted nothing more than to connect with others. And he was one hell of a rocker. #JoeStrummer #TheClash

Christmas edition🎄of #MitochondrialDisease collection of papers! 🎁 📚 biomed.news/bims-mitdis/... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social Fuel your mitos well and happy holidays!

Billet du 17 décembre. Mistral Gagnant. Où l'on apprend, entre autres, combien a coûté l'agent conversationnel IAg acheté par le CNRS, Emmy. « Il faut souffler sur quelques lueurs pour faire de la bonne lumière. » René Char rogueesr.fr/mistral-gagn...

Good Sunday all. The last weekly issue of papers in #cancermetabolism and #mitochondrialbiology before Christmas is out: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading I wish you all a great Holiday Season and Merry Christmas to all who celebrate it.

This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: The G3BP stress-granule proteins reinforce the integrated stress response translation programme www.nature.com/articles/s41...

"The Clash: Tory Crimes and Other Tales" (Prime): wow. What a great punk rock documentary. Interviewing key players saying fascinating things, interspersed with cuts of The Clash kicking ass live. As a lifelong fan, I realised how little I had known, and I love The Clash all the more for it.

Bonsoir @inserm.fr vous surveillez Laurent Toubiana ? Apparemment pas assez car il savait ce que devait donner l'étude @epiphare.bsky.social sans avoir les données car le ministère a refusé de donner 15k€ à un informaticien antivax notoire pour qu'il s'asseye sur le secret médical en 2 semaines

Very pleased to share our new review "The Evolving Landscape of Brain Metastasis" in @cp-trendscancer.bsky.social 🧠🔬🧪 Grateful to an outstanding team of co-authors, all pioneers in the #brain #metastasis field and to @valientelab.bsky.social for co-leading this 🙏🏻 Link: www.cell.com/trends/cance...

Hi everyone, it seems difficult to obtain the Thy1-RFP mice originally generated by G. Feng et al. Does anyone know of an alternative mouse line that expresses an RFP sparsely and suitable for morphological analyses using confocal or light-sheet imaging? Thanks in advance. 🙏

Anyone to help my man @npanayotis.bsky.social who's looking for a mouse with sparsely-labeled neurons?

Now online! HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

J'ouvre les nouvelles: -Fusillade a l'université Brown aux US -Fusillade sur une plage à Sydney. Je ferme les nouvelles.

Mechanosensor-mediated Hsp70 phosphorylation orchestrates the landscape of the heat shock response www.nature.com/articles/s41...

#Autophagy and #mTOR papers from last week, with our review on the top, enjoy! biomed.news/bims-auttor/...

Weekly roundup of the latest progress in analytical chemistry for metabolomics and lipidomics analyses. biomed.news/bims-metlip/... A collaboration with @biomednews.bsky.social

Publication du rapport d'évaluation de l'Inserm par le HCERES www.hceres.fr/fr/dossiers-...

Good Sunday, all! What a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology. I couldn't stop selecting!! biomed.news/bims-camemi/... Biomed News "There are three musts that hold us back: I must do well. You must treat me well. And the world must be easy."-Albert Ellis

Vimentin intermediate filaments support autophagosome biogenesis at ER-endosomes contact sites in response to starvation www.biorxiv.org/content/10.6...

This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: LRRC59 cooperates with nuclear transporters to restrain the nuclear envelope repair machinery and safeguard genome integrity www.nature.com/articles/s41...

COMP, PSC non compensée, non financement du CAS pension. Des acronymes pour des budgets d’universités contraints par un gouvernement sans ambition pour la France, sa recherche & sa jeunesse. Nous voulons un service public de #ESR condition de l’indépendance industrielle et intellectuelle. #VeilleESR

Aucune image ne pourra mieux résumer l’invisibilisation du travail sous le capitalisme : on remplace des ouvriers qui prenaient des risques physiques par des gens qui n’ont strictement aucune probabilité de perdre quoi que ce soit et dont on ne sait pas au juste ce qu’ils produisent

The dark proteome: translation from noncanonical open reading frames 1⃣5'-UTR 2⃣3'-UTR small ORF/sORF 3⃣out-of-frame 4⃣In-frame overlapping ORF Translating micropeptide <100aa, proteins distinct from canonical ORFs, or isoforms #TrendsCellBio 2022 www.sciencedirect.com/science/arti...

"C'est un vrai cri d'alarme" : de Lille à Angers, des universités alertent sur leur situation financière www.franceinfo.fr/societe/educ... @afp.com @franceinfo.fr

Dix ans après les Accords de Paris, Valérie Masson-Delmotte, paléoclimatologue au LSCE, revient dans une conférence en ligne sur les relations entre réchauffement climatique et les impacts sur notre corps et notre système de santé.

Silence assourdissant de nos comploplos proTrump qui trouvait que le pass sanitaire etait La diCtAtURe

Ancestral Chaperonins Provide the First Structural Glimpse into Early Multimeric Protein Evolution Magnifique papier et en plus qui va dans le même sens que ce qu'on disait en 2021 dans un de mes papiers sur la topologie et l'émergence du Groupe 3 des chaperonines. academic.oup.com/mbe/article/...

Paging @agencerecherche.bsky.social @enseignementsup-recherche.gouv.fr 😬 #ESR

#veilleESR « Les universités françaises en grande difficulté financière, celle de Lille affiche un déficit record » #ESR #Université www.leparisien.fr/etudiant/etu...

[ #VeilleESR #LRU ] L'Université PSL appelle à un financement pérenne et ambitieux de l’ESR. « Sans université forte, pas de souveraineté économique et technologique » psl.eu/actualites/s...

"vous n'aurez pas ma liberté d'avoir un tank de 2 tonnes et de rouler à 50 dans une zone limitée à 30 avec commerces et écoles".

bientôt le moment où même en tant que piéton va falloir se balader avec une gopro sur la tête pour documenter les violences motorisées, comme ça se fait déjà dans certains pays.

Sinon ça fait 3 fois en quelques mois qu'un mec en grosse bagnole fonce pour forcer le passage piéton alors que je suis engagé dessus, avec mon enfant. Quand je dis engagé dessus, je veux dire que je suis en plein milieu de la route, pas que j'ai fait un petit pas. Le nombre de fous furieux augmente