Carol of the Bells in # Kyiv subway. Voices of the Embassies of Germany, France, and the United Kingdom came together to perform Shchedryk in the Kyiv metro as a sign of solidarity with Ukraine. Thankful to everyone who stands with us!

The Senate version of the NIH appropriations bill has language that limits the use of multiyear/upfront funding. Please call your Senators and Representatives to make sure it is in the final bill. We must stop the brain drain in our research workforce before it's too late.

Happy Festivus, y'all. www.youtube.com/watch?v=1njz...

Study of over twenty five million people over almost four years finds that COVID vaccines reduced COVID deaths by 74% and increased all-cause deaths by zero. I don’t know how much clearer it can get than that. jamanetwork.com/journals/jam...

The pulled 60 Minutes piece has nothing in it especially surprising. www.thereset.news/p/breaking-h...

Must say, while interviews with established PIs with deep cuts to their funding are important, the principal and longest term effects are on the trainees. An entire generation wiped of confidence.

Helene was so giving to others about her battle, and went through to make it into maybe the top 1% of survivors of pancreatic cancer, before succumbing Dec 19, 2025 all while losing her father to it. She supported @letswinpc.org and the family asks for you to consider supporting them as well.💔

I loathe boxing, but I can't help logging into these Jake Paul fights. Professional boxing is no different than WWE, but less entertaining.

Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪

for those in my boat, the designation has changed on my grant from yesterday to this new pergatory

Dear NIH community. You've done so well despite all the shit I've created. I look forward to being on more podcasts in the year ahead.

Today, Trump declared that the nation will host the first-ever “Patriot Games,” an “unprecedented four-day athletic event” featuring high school athletes, one boy and one girl, from each state and territory. If you think this sounds like The Hunger Games, you're not alone.

Leaving my #NSF office for the last time, again

(I will vote for any presidential candidate that commits to moving NSF back into their building within the first 30 days of swearing in)

NSF bio hour - NSF BIO lost 40% of its staff 😑

Thread

Horrifying news being confirmed about the state of NSF at the NSF IOS/BIO webinar

We can't work with foreign collaborators, but they can send money to a foreign PI to conduct an ethically questionable study in a vulnerable population in another foreign country? This is what corruption looks like.

The US is losing blue-collar jobs for the first time since the pandemic—year-on-year job losses have hit 65k as manufacturing, transportation, & mining industries lose jobs at a rapid pace while growth in construction has nearly zeroed out

It's to inactivate all the environmental methyl groups. Your lactase genes will thank you.

"(Memoli's) actions look like those of a leader who has been given broad discretion to shrink down the agencys infectious-disease work—an area where he may have a few personal grievances. “People are afraid of him,” one official said, pausing. “I’m afraid of him.” www.theatlantic.com/health/2025/...

Psst: Postdocs, figures should not be included in your specific aims page. Now you know for Feb/March submissions. grants.nih.gov/grants-proce...

find it remarkable that folks upload the unpublished, confidential work of others to those sites.

In Philly news, the Delco Pooper gets community service

Wait, I retract my previous tweet. THIS might be the dumbest thing I’ve ever seen.

Good grief. HHS is being led by idiots.

NSF now planning to let POs largely decide what gets funded, and to send PIs reviews that are only 3-5 sentences long. They don't have to use outside reviewers (except maybe 1) and don't have to convene panels. (1/5)

Brave to say this on BlueSky, the Philadelphia App.

Hmmmm www.statnews.com/2025/12/15/n...

Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there?? #CellBiology #WTFology www.biorxiv.org/content/10.6...

Eat your folates to methylate, drink your vitamin C to demethylate. This is why I have cereal and orange juice for breakfast every morning to maintain equilibrium.

absolutely losing it at my 14yo's biology homework

Yet another "glad I got out of TX" affirmation

Counterpoint to the article: “Loss of promising talent supported by these [DEI] programmes will substantially weaken our research capacity, limit innovation and substantially reduce discoveries important for driving scientific advancements.” pubmed.ncbi.nlm.nih.gov/41131402/

This is classic scitwitter from the olden times. The fact that the blog post is in Georgia is just icing on the cake.

Magaziner: How many US military veterans have you deported? Noem: We have not deported military veterans. Magaziner: We are joined on zoom by a gentleman who is an army combat veteran who was shot twice while serving our country. You deported him to Korea.

HAHAHAHAHAHAHAHA Water causes diabetes. Inject the Pepsi Max directly into my veins.

NSF - Forced reorg - POs down ~ 40% (DRP, most rotators not renewed, retirements) - Forced move (and we have to pack and clean) to a building with no furniture, little to no conference space for panels, inadequate 🛜, …) I personally love the boxes they gave us for packing. “Details matter” 🙃

Ok, it’s time for Tanner McKee

Wow, this meta analysis was entirely fictional. This thread reveals that it appears to be AI generated bullshit loaded with fake citations. We are entering a very worrisome situation where AI can generate papers that look real at a glance—this one fooled me too.

Trump state capitalism update, as the nation drifts further and further away from free markets.

"The only reason I don’t have this funding is because my last name is Rodriguez,” he said. “It has nothing to do with the science." STAT on the betrayal of early-career researchers: www.statnews.com/2025/12/08/t...

One of the things I was most excited about 1yr ago was joining 1 of the MOSIAC UE5s as a project scientist to work with those ECRs assigned to it. The opportunity to serve our greater communities. Truly a program that supported people across broad institutions, unlike the parent.

Use AI to write an NIH grant in 10 minutes! Not linking directly but it is called grantease. Holy crap we are doomed.

they couldn't find gold letters?

Good grief (gift link) wapo.st/3MeKCkf

RFK Jr: "Two weeks ago we ended, under your leadership, a twenty year war on women". Three out of five men in this shot have been accused of sexual misconduct, harassment or abusive behaviour towards women. A fourth signed into law a near-total abortion ban in his state as governor.