Most labs are always a single grant away from going under

Today in "everybody is firmly convinced that they and their type of science is at particular and specific disadvantage at the NIH no matter any evidence to the contrary".... drugmonkey.wordpress.com/2026/02/22/n...

Check this out straight from the NIH website, acknowledging that multiyear funding was likely responsible for a 20% decrease in early stage investigators. And that it was expected. A strange approach for someone so committed to the next generation of scientists. grants.nih.gov/news-events/...

Other European countries are doing the same thing and investing a lot of money. Watch this space.

Well, there goes the entire business model for Biorender. arxiv.org/abs/2601.23265

NIDA: 0 NIAAA: 0

The NIDDK has still only issued a total of 3 new R01s since October 1.

This is not true. MYF is capped at FY25 levels, where 39% of all awards were MYF. We need to be very precise about this because the impact is enormous.

Solution? Hire more administrators. See how this works?

Can we still add a link to our NCBI page in the new biosketch? I guess it could be added to the personal statement section.

A further blow to UK science and Universities 😱 www.timeshighereducation.com/news/three-u...

So, how are you guys listing your pubs in the contribution to science section in the new SciENcv?

What we also need to factor in now is that a lot of A0s with very competitive scores will be coming back in as A1s. That would have an enormous impact, even under normal conditions, but now it's just a total disaster.

Calafiori and Havertz in the starting XI. I got my joy back.

3 new R01s funded by NIDDK this FY.

Everything is a "resubmit" right now.

We stop talking about percentiles, paylines etc like it's the before times. Admin and leadership are still doing that because it still hasn't hit them yet. POs don't even know what the rules are anymore so grant reviews are just performative. We're working back channels to get our grants funded.

I do not trust the Democrats to get this DHS/ICE funding/shutdown thing right. They have demonstrated over and over again that they are pathetic in opposition.

We're definitely facing another NIH shutdown now. The organization is already essentially frozen, so I expect that to just continue. Absolute shambles.

Now applications are getting kicked to SEPs due to a "surge in applications". Everything is fine.

We don't need councils anymore. www.nature.com/articles/d41...

A reminder for the reviewers of #NIHGrants "Nice" NIH study sections screw their applicants because of the way NIH calculates percentile. drugmonkey.wordpress.com/2025/11/20/n...

🧪IMPORTANT! This graphic explains how science all over the US is funded. Congress approved a 2% increase in the #NIH budget for FY 26. Buried in the bill- Shift of ~40% of grants to MYF. This will still result in a 35% DECREASE in the NUMBER of grants funded per yr. Russel Vought is behind this.

Please make it stop.

Trump's speech is so excruciating that it's actually making me sympathize with the greedy bastards at Davos.

Reposting with comments. NIDDK budget appears to be cut because there is a separate fund for diabetes, elsewhere in the bill. NINDS budget is increased because of funds transferred from the Office of the Director (OD) for ALS, Alzheimer's. NIEHS seems like a real cut. OD cut is related to NINDS.

This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again. www.nature.com/immersive/d4...

Considering the impact of Multi-Year Funding at NIH drugmonkey.wordpress.com/2026/01/20/c...

Good news for NIDDK I did not include a special fund for diabetes that is administered through NIDDK. This likely accounts for the difference, but I am trying to find the numbers in the bill. More to come...

The language is strong enough that they cannot do that. Though they might find other ways. The fact that Vought threatened a White House veto over this actually makes me think this language mattered a lot. That he doesn't have an easy way around it.

Celebrating this "compromise" on LinkedIn like this is an interesting choice.

Just spoke to The Hill about how the dismantling of the NIH is impacting science in America. We still face a cliff of unfathomable heights, w easily 1000+ labs poised to close in the next year due to funding ending. A generation of young scientists lost because there is nowhere for them to train.

Disaster

MYF and a 4% budget cut for NIDDK. This is absolutely awful.

What's been lost, so far. "Program officers steward research portfolios. They don’t just process applications. They understand scientific contexts, see connections across studies, mentor investigators, and help translate broad priorities into fundable research programs." substack.com/inbox/post/1...

I'm in a environment where most of my trainees and staff (and Dept admin) support the current regime politically, which makes communicating these issues delicate, complicated and not especially safe. It's been a dreadful 12 months.

Yeh but they only got a 3.4% budget cut so....victory.

I think a substantial enough budget increase to offset the 50% to 100% MYF scheme they want to implement is a pipe dream. Not mention, this is not about getting to MYF. This is about destroying NIH and the academic research community. The destruction is the point.

All is see is that 42% think it's been a success. Genuinely astounding.

You underestimate the degree to which Russel Vought and the project 2025 crew want to destroy science and the NIH. Science and truth are very inconvenient for authoritarians.

Susan Collins is the senate appropriations chair. We're fucked. archive.li/FLo9Z#select...

The MYF trick was always a backdoor to significant NIH cuts. One of Vought's "smartest" moves. He really hates the NIH.

Current state of @mlkwritedit.bsky.social website. Sign of the times.

I have been modeling the impact of multi-year funding. Based on fairly reasonable assumptions, 50% multi-year funding, the number of new and competing awards is anticipated to drop to approximately 6000 compared to 10,000 had there been no multi-year funding above the historical background rate.

I think this was assumed, but this might be the first public acknowledgement. The only hope is the senate HHS appropriations package that explicitly blocks MYF. I don't see why the house will block it, but it needs to be passed.

Gratitutde to all NIH study section participants who are participating in rescheduled meetings now and in January. Thank you for your service and thanks also to the hard working NIH staff who are making these happen. 🥰🧪

Should an 85 year old get a new 5 year R01? I don't think so. But the real question is why the f**k would an 85 year old want one?

Here are the data for type 1 R01s at NIDDK for the same period in each fiscal year (FY): FY26: 0 FY25: 34 FY24: 28 Make it make sense.

The old NIH (RIP) tried that. The Oldz killed it, remember?

why is the focus *always* on the far off future instead of the people right here and now that should be in the full flower of their productive careers? Particularly given that we've had heavy handed quota based affirmative action for ESI in place uninterrupted since 2007.