Immigrants, particularly on H1Bs, are the lifeblood of American innovation. If you wanted to hurt US competitiveness in the next century, I can think of few more effective ways than a move like this Even when found illegal, the mere intent will have irreparably harmed our future

Important to remember that H1B visa holders have their whole life in the US. The home they rent or own is here. Their family. Their kids go to school here. Being locked out of the US is also in many cases rendering them homeless and away from their family, with no obvious path to return

So can I ask for all reviewers who don't like my papers to be fired? Or nah?

A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails. Not an easy job under the best of circumstances and right now it's the pits. Thank you!

A deep dive into the destruction of US cancer research by @jonathanmahler.bsky.social “It’s an absolutely unmitigated disaster,” a former top official at NIH told him. “It will take decades to recover from this, if we ever do.” Gift link: nyti.ms/48iH3Cr

Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures. @nachury.bsky.social www.biorxiv.org/content/10.1...

Moving into a cabin deep in the woods and going totally off-grid is sounding awfully attractive right now. Anyone want to join me?

The GRFP lives!! (due end of October) www.nsf.gov/funding/oppo...

New review on how changes in cell type composition in and outside the brain contribute to the evolution of behavior. 🧪 authors.elsevier.com/a/1lihM,LqAZ...

New preprint! How are developmental cycles coordinated across cell types? It turns out that, like Geppetto's cuckoo clocks in the GIF below, individual cell types are each performing their own little crazy routine, but all in sync with each other.

We're going to see a lot of bullshit in the coming days and weeks about "causes of autism", and most will be based on flawed, over-interpreted observational studies (1/n)

Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be."

Farmers offering fantastic fungi

Harvard wins lawsuit regarding withheld grant funding [Gift Link] wapo.st/47tdz4A

If you’ve ever compared unvaccinated kids to vaccinated kids, you’ve seen the former are more likely to die.

Thing is, the Noem & Homan Show has yet to come to a city that's just terribly designed. We give your GPS nightmares. We love a sudden dead end. We have like 19 Washington Streets & none of them have street signs bc fuck you. You took a left? Surprise, motherfucker, you're at Logan Airport. Forever.

The devastating flu epidemic of 1918 was particularly dangerous for young adults, for people in their prime, who died by the millions. But RFK Jr. is too stupid to know that. Link below.

OK - he is now finally in for it. Do you know what happens when you make toddlers mad????!

Feeling mitochondrially challenged lately? Here are two classic reviews on #mitochondria that should help. www.cell.com/current-biol... www.cell.com/current-biol...

Very few PhD students finish within 4 years. But international students will need to do that if US proposed visa rules change go through. Sound reasonable to you? Fed register is accepting comments for next month. Details at the link & comment button www.federalregister.gov/documents/20...

I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions. Descriptions and links in the following two posts.

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

Ukrainian Independence Day celebration. St John’s, NL, Canada.

If you’re interested in ants, olfaction, gene regulation, or all of the above, here’s a new preprint from the lab for you. It describes an unorthodox mechanism of transcriptional interference by which ant olfactory sensory neurons produce a single functional receptor. www.biorxiv.org/content/10.1...

Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns? To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠 #preprint thread ⬇️1/8

A legend. Was and am still inspired by his work. Sad to hear this.

Puffins. Howling cold wind. Wild coastal scenery. Few people. Paradise.

More new science from the lab! Led by @nathancsharris.bsky.social (now at GA State) and PD Priya Dutta. We describe how experience tunes the ratios of functional receptors in a single sensory neuron via coordinating transcriptional and post-transcriptional mechanisms to drive response plasticity.

📢 Fresh off the press! Our article on Arc is out in @currentbiology.bsky.social: www.cell.com/current-biol... 🧶 Full thread on our discoveries here: bsky.app/profile/thec...

12 examples of how developmental biology research led to fundamental discoveries for biomedical research. There are many more! Download ppt & jpg versions on @socdevbio.bsky.social website. Use & modify as needed. Poster formats are also posted to print & hang in your lab!

🔥my latest paper from @odedrechavi.bsky.social lab🔥 we found small RNAs act across tissues to regulate fertlity in C. elegans 🪱. Surprisingly, we also found that O2-sensing neurons inhibit germline maintenance. Follow along our journey👇https://www.biorxiv.org/content/10.1101/2025.08.07.669182v1

I went to Bryn Mawr but majored in Biology at Haverford (and lived there my senior year). Really great school and department. Lots of opportunities and resources for undergrad research (entirely my fault that none of my experiments worked 😅). Apply!

Just. Fucking. Stop.

This would more or less halt the ability of scientists and academics from visiting the US to give talks, attend meetings and workshops, collaborate with peers on research and I think that is the primary point. 🧪

Congrats to Kristen Verhey ‪@kjverhey1.bsky.social‬, winner of @ascbiology.bsky.social's Sandra Masur Senior Leadership Award. She combines remarkable scientific insight into molecular motors with leadership and mentoring in cell biology 🧪 www.ascb.org/society-news...

We need a new microscope objective. A $1.6k tariff for something that you can hold in your hand and that is only manufactured in Germany

Donate if you can!

NPR and PBS. A national tragedy and travesty. Just unimaginable.

Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...

Extra kudos and thanks to all the staff at NIH and NSF and other federal funding agencies for working extra hard in very small windows of opportunity to get grants reviewed and funds released before the attention-addled federal policies change again (on an hourly basis).

🧪BREAKING: NIH has laid out 5 options for funding publications costs on grants (yes, FIVE!). This is hugely impactful. Make your opinions known by September 15, fellow scientists. 🧪 grants.nih.gov/grants/guide...

How do animals decide if they should forage for food or stay home to take care of newborn offspring? Whose needs come first? For my PhD work now out in Nature, we examined how hunger and parenting neurons interact and are reshaped postpartum in mice 🧵⬇️ www.nature.com/articles/s41...

Well, none of us may ever get funded again but in the meantime, here's some new science! Led by recent PhD Anjali Pandey w/ex-UG Maya Katz. Here we identify an asymmetric molecular mechanism that underlies symmetric context-dependent sensory plasticity in the AWC olfactory neuron pair in C. elegans

For the life of me, I cannot fathom the rationale for any of this. Utter wanton destruction of one of the best research ecosystems in the world.

Want to publish a NIH-funded paper in Nature? Well - unless your institution has an agreement with Springer, you'll have to be mega-rich to be compliant with NIH's new no-embargo policy. Springer is insisting on gold OA - that's $12,690 and that's extortion.

Proud to introduce Dr. Anjali Pandey who did a great job at her thesis defense and talk today. She is PhD #20 from the lab. Preprint link and associated bluetorial coming soon!

This below is correct. I just got confirmation as well. Key though is to upload the unformatted version - meaning not the journal formatted PDF but the manuscript version that was accepted. And for several journals - you will have to do the submission yourself (make it CC-BY and link your grants!)

How are people dealing with journals that continue to embargo NIH-funded articles for 12 months unless you pay an exorbitant OA fee? Just not submit to them? Or is there a workaround for compliance with the new NIH immediate release policy?

The Anne West lab at Duke is hiring a postdoc to work on nuclear cell biology in neurogenesis. Please help me spread the word! Applications to [email protected].

My fabulous colleague (and ex-postdoc) @inechipurenko.bsky.social and I (mostly Inna!) wrote a review extolling the many virtues of C. elegans for the study of cilia biology. A really interactive and collaborative community of people working in this field too. www.sciencedirect.com/science/arti...