Helene was so giving to others about her battle, and went through to make it into maybe the top 1% of survivors of pancreatic cancer, before succumbing Dec 19, 2025 all while losing her father to it. She supported @letswinpc.org and the family asks for you to consider supporting them as well.💔

Friday we lost a brilliant mind, colleague, and friend to her battle with pancreatic cancer. Those who knew her will remember Helene Andrews-Polymenis for her warmth, generosity and leadership. She will be missed by many. RIP

A lovely tribute to Amos Bairoch from Vivienne Baillie Gerritsen, author of the always interesting Protein Spotlight blog for #SwissProt www.proteinspotlight.org/back_issues/...

@markowenmartin.bsky.social congrats on your retirement!

My @edwardmarcotte.bsky.social PhD labmate is now a PI and has a new preprint applying #machinelearning to #proteomics, check it out!

Vision models have directions in embedding space for concepts like “stripes” or "corgi" We show that protein language has directions for motifs, use this as a new way to detect and localize motifs! New preprint w/@ahmadshamail.bsky.social Feedback very welcome arxiv.org/abs/2511.21614 1/4

Calling all postdocs! Applications are open for Dept. of Molecular Biosciences 3rd Trailblazers Postdoctoral Symposium @utaustin.bsky.social. Come to Austin, meet your peers, showcase your work. Application is easy and all expenses are paid! Spread the word! tinyurl.com/yw7ffjn9

🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.

Happy to share our fun team-up with @centriolelab.bsky.social & @stearnslab.bsky.social to reveal the architecture of the mammalian centriole’s Distal Ring 🛟. Very cool multiscale integration of #UExM 📏🔬with #CryoET ❄️🔬. Congrats to @ebertiaux.bsky.social & @computingcaitie.bsky.social #TeamTomo 🧪

Confused by all the histones that are cropping up in organisms that are decidedly NOT eukaryotes? check out our review - fantastic work by team NucEvo in the #Lugerlab The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms - www.annualreviews.org/content/jour...

I’m curious if anyone has heard anything about the status of the NIGMS R35 MIRA, currently there is no next submission deadline for established investigators and we have now passed the forecasted new announcement date

We are deeply saddened to share the passing of Amos Bairoch, pioneer of bioinformatics and co-founder of SIB. His lifelong commitment for high-quality, open data transformed global research. We honour his legacy by continuing to build the future of bioinformatics.

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

This is a nice explainer of the search for Asgards happening right now off the coast of Uruguay. I was lucky enough to visit the R/V Falkor (too) [named for The NeverEnding Story!] while it was docked in Montevideo... (pics below) bsky.app/profile/c0nc...

Today's dive site, to ~2,200m. We will be streaming 9am-3pm Central. At www.youtube.com/@SchmidtOcean #AsgardArchaea @schmidtocean.bsky.social @moorefound.bsky.social @texasscience.bsky.social @utmsi.bsky.social

This team are searching for new "Asgard archaea" to sequence. Let's talk about why these bacteria-like organisms are so fascinating, why they're named for Norse mythology, and why looking at them is unlocking a better understanding of our own genomes. Once considered a type of oddball bacteria🦠...

Congratulations to the newly minted Dr. Brittney Voigt! After defending a fantastic thesis spanning work in my lab and the @edwardmarcotte.bsky.social lab.

Integrative Biology at UT is hiring an Evolutionary Biologist! Happy to answer any questions about the position/dept/UT. Come join us! integrativebio.utexas.edu cns.utexas.edu apply.interfolio.com/177547

Really enjoying watching science happen in real time, with @archaeal.bsky.social, @valdeanda.bsky.social, and colleagues live streaming their robot sub data collection from the R/V Falkor off of the coast of Uruguay

Starting at 7pm Central I will be streaming from the bottom of the ocean off the coast of Uruguay! Feel free to join and ask questions. www.youtube.com/@SchmidtOcean

Asgard collaborative expedition begins… Falkor (too) has left Montevideo

My department at UT Austin is looking to hire an Assistant Professor in Evolutionary Biology, broadly defined. Feel free to reach out to me with any questions you may have. apply.interfolio.com/177547

A wonderful collaboration between my lab and Andy Ellington and Edward Marcotte here at UT. We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)

🌍Open call: Junior Group Leader positions! Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery. Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...

Baker Lab 2025 The container is our field gear for the research expedition for Uruguay. sites.utexas.edu/baker-lab/sp...

We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

New: Researchers are broadly rejecting the Trump administration's compact. In faculty votes and student protests, they have mobilized to pressure their universities—to some effect: 6 of the original 9 universities have rejected the compact With @alexwitze.bsky.social and @jennaahart.bsky.social:

Congratulations to this year's cohort of Packard Fellows! @packardfdn.bsky.social Such a great program, especially needed in these times. www.packard.org/insights/new...

So sad to hear the news - John truly was an inspiration to so many, and one of a kind. www.cam.ac.uk/research/new...

So much fun to host @edwardmarcotte.bsky.social at the @biozentrum.unibas.ch and introduce him to the @cellarchlab.com, thanks for a wonderful Discovery Seminar!!

Delightful to finally meet you @edwardmarcotte.bsky.social and hear about your crazy cool science exploring the proteomes of all the diverse beasties on the planet to reconstruct LECA 🧪🌎. Now I see where Caitie gets it from 👨‍🔬👩‍🔬

EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬 The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩‍🔬🤓

Love #protists? Then you'd love this! Beautiful collection of hand-drawn critters represented here at the Oxford-Japan symposium on ethological dynamics in diorama environments sites.google.com/view/oxford-... #ciliates #testateamoeba #diatoms

Meet the CAGE: a newly-discovered protein nanocapsule💊, conserved from bacteria to eukaryotes! Looks more like an eclair🍩 than a prezel🥨. This protein pastry now makes us wonder- what's the filling!? Huge congrats to the ever-amazing @computingcaitie.bsky.social, now at the @biozentrum.unibas.ch 🧪🧶🧬

I am excited to share our new preprint on the CAGE complex, a mysterious hollow protein complex that I first saw years ago while surveying Tetrahymena ciliary lysate www.biorxiv.org/content/10.1... #cilia #protistsonsky 🧬🧪

The #PRETZEL is out !!! Okay the CAGE renamed now fine. Congrats @computingcaitie.bsky.social and team!!

YAYYYY, Immune systems of choano !!!! Beautiful to see how knowledge about bacterial immune systems illuminate immunology in diverse organisms with the always incredible biochemistry and structural approaches of @kranzuschlab.bsky.social. Wonderful work @yao-li.bsky.social 👏

Super excited for the full data, especially to see which of the over 400 screened binders actually got us the third place 🥳 Shout-out to the organizers for this very cool competition!

🚨The Bits to Binders Competition has concluded!🧬 One year ago we gathered scientists from around the world to design and submit protein binders that cause immune cells to target and eliminate CD20+ tumors Spoiler: They work!

Wishing a happy 83rd birthday to mathematician Karen Uhlenbeck, winner of the 2019 Abel Prize for her work applying gauge theory to four dimensional manifolds. Here is her story! tinyurl.com/ybmvcbpx #WomenInSTEM #MathSky #HistSci 🧮

‼️ Exciting new preprint from a close collaboration with Kylie Walters' group. Our study maps the binding sites of key regulators of the proteasome in situ. www.biorxiv.org/content/10.1...

Daily Bruin article about the ~800 frozen grants at UCLA including some from my lab dailybruin.com/2025/08/02/a...

We are excited to share our preprint describing DirectContacts2! Here we develop a machine learning model to discriminate between direct and indirect protein interactions. We use our model to construct a highly accurate wiring diagram of the human cell. www.biorxiv.org/content/10.1...

Scientists, please take a moment to comment on these plans to limit animal testing in drug regulation and biomedical research. Use whatever experience you have to make your comments specific to you. The law requires regulators take these comments into account, so it might help. Mine is attached.

This is great! Thank you. Can the SIB help to keep the CASP challenge running?

We will be hosting a mirror site of the CASP data and workflows at @sib.swiss. Operating a redundant site with independent funding is a good idea for important scientific infrastructure, independent from the current funding situation in the US.

Speak up to prevent a major loss for the field. CASP, which helped shaping structural biology including AlphaFold is on the verge of shutting down. NIH funding has lapsed, UC Davis support ends and the core team is being let go. Painfully shortsighted.

Congratulations to Kohl Kato and Pete Cullen and all involved in this tour de force characterising mutations in the Commander complex leading to Ritscher-Schinzel or 3C syndrome. @peterjcullen1.bsky.social www.science.org/doi/10.1126/...