Postdoc position available!!! We are looking for a creative postdoc to develop independent research directions in tissue morphogenesis using embryos, stem cell/organoid systems, and quantitative imaging and/or biophysics. Here are the details: livejohnshopkins-my.sharepoint.com/:b:/g/person...

Its not cryoEM, but still happy for the shout out @cryoempapers.bsky.social 😆

These are the curves for new and competitive renewal grants. The number of new awards is increasing slightly, but only slightly. 17 out of 25 institutes and centers with funding authority have now made awards. 3/4

“In summary, 2 large, randomized, placebo-controlled clinical trials in highly relevant populations show that starting metformin at the time of acute infection with SARS-CoV-2 is safe and lowers the risk of developing long COVID.” academic.oup.com/cid/advance-...

It has been two weeks since the unexpected death of Peer Bork, and all of us in his research group are deeply missing him. His scientific vision brought us together as a team, and we are immensely grateful for the time we spent together. 🧵

We have a nice example of convergence in this preprint as well: pubmed.ncbi.nlm.nih.gov/40297438/ Branched-chain α-keto acid dehydrogenase complex + two regulators. BCKDK and BCKDK only dicovered with rare variants; PPM1K, DBT and DLD only discovered with common variants. All associated with BCAAs.

New lab preprint - Common and rare variant studies for the same trait identify different genes and here Diederik Laman Trip developed a protein network AI enconding to investigate if traits studied by different approaches converge on the same molecular pathways www.biorxiv.org/content/10.6...

In patients with melanoma who had surgical removal of tumor, receiving a customized mRNA cancer vaccine increased protection against recurrence by 44% at 2 years when compared to standard therapy. At 5 years, it appears that protection slightly increases to 49%.

Take a minute to guess at what you're looking at.⌛ This is a scanning electron micrograph of rat epithelium ('outer surface') from the bronchial tubes. The round-top cells are goblet cells that secrete mucus, the hairlike projections are ciliated cells which beat to move the mucus... (🔬: Hitachi)

Very sad to hear about the passing of Peer Bork, one of true giants of computational biology www.embl.org/news/embl-an...

📢 The Louis-Jeantet Foundation is happy to announce the 2026 #LouisJeantetPrizes, awarded to YASMINE BELKAID @pasteur.fr and to FIONA DOETSCH @doetschlab.bsky.social hlab.bsky.social @biozentrum.unibas.ch @unibas.ch CONGRATULATIONS!!! 👉 jeantet.ch/en 👇 follow thread

How did eukaryotic cells with complex architecture evolve from simpler prokaryotic cells? DNA analyses offer possible answers @nature.com www.nature.com/articles/d41... www.nature.com/articles/s41... @bristoluni.bsky.social www.nature.com/articles/s41... www.nature.com/articles/s41...

Great things still happen all around us. Each your UNC Biology's Bob Goldstein and Art's Beth Grabowski co-teach ARTS/BIOL 409, that brings together artists and scientists to explore an intersection of two disciplines. It culminated this year with a remarkable show Friday 1/n

Human coronavirus 229E antibodies and Spike structure function paper is finally out for real. Led by @wrapplab.bsky.social (wrappers delight) and @mlicc1701.bsky.social (MFL) #lovevirology #229E #antibodies www.nature.com/articles/s42...

NEW article by me! We can now visualize pathogens down to atoms; design vaccines in weeks; manufacture them in microbial factories; engineer them more precise than ever before. We're living through a golden age of vaccine development, but only if we continue to invest in them.

Our Perspective article on Computational Strategies for Cross-Species Knowledge Transfer is now published in @natmethods.nature.com! This was a collab b/w @krishnanlab.bsky.social & @fishevodevogeno.bsky.social, led by the amazing Hao Yuan @yhbioinfo.bsky.social. 🧵 www.nature.com/articles/s41...

New post! There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost. Medical breakthroughs in 2025. Plus a serious note at the end. www.scientificdiscovery.dev/p/medical-br...

Helene was so giving to others about her battle, and went through to make it into maybe the top 1% of survivors of pancreatic cancer, before succumbing Dec 19, 2025 all while losing her father to it. She supported @letswinpc.org and the family asks for you to consider supporting them as well.💔

Friday we lost a brilliant mind, colleague, and friend to her battle with pancreatic cancer. Those who knew her will remember Helene Andrews-Polymenis for her warmth, generosity and leadership. She will be missed by many. RIP

A lovely tribute to Amos Bairoch from Vivienne Baillie Gerritsen, author of the always interesting Protein Spotlight blog for #SwissProt www.proteinspotlight.org/back_issues/...

@markowenmartin.bsky.social congrats on your retirement!

My @edwardmarcotte.bsky.social PhD labmate is now a PI and has a new preprint applying #machinelearning to #proteomics, check it out!

Vision models have directions in embedding space for concepts like “stripes” or "corgi" We show that protein language has directions for motifs, use this as a new way to detect and localize motifs! New preprint w/@ahmadshamail.bsky.social Feedback very welcome arxiv.org/abs/2511.21614 1/4

Calling all postdocs! Applications are open for Dept. of Molecular Biosciences 3rd Trailblazers Postdoctoral Symposium @utaustin.bsky.social. Come to Austin, meet your peers, showcase your work. Application is easy and all expenses are paid! Spread the word! tinyurl.com/yw7ffjn9

🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.

Happy to share our fun team-up with @centriolelab.bsky.social & @stearnslab.bsky.social to reveal the architecture of the mammalian centriole’s Distal Ring 🛟. Very cool multiscale integration of #UExM 📏🔬with #CryoET ❄️🔬. Congrats to @ebertiaux.bsky.social & @computingcaitie.bsky.social #TeamTomo 🧪

Confused by all the histones that are cropping up in organisms that are decidedly NOT eukaryotes? check out our review - fantastic work by team NucEvo in the #Lugerlab The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms - www.annualreviews.org/content/jour...

I’m curious if anyone has heard anything about the status of the NIGMS R35 MIRA, currently there is no next submission deadline for established investigators and we have now passed the forecasted new announcement date

We are deeply saddened to share the passing of Amos Bairoch, pioneer of bioinformatics and co-founder of SIB. His lifelong commitment for high-quality, open data transformed global research. We honour his legacy by continuing to build the future of bioinformatics.

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

This is a nice explainer of the search for Asgards happening right now off the coast of Uruguay. I was lucky enough to visit the R/V Falkor (too) [named for The NeverEnding Story!] while it was docked in Montevideo... (pics below) bsky.app/profile/c0nc...

Today's dive site, to ~2,200m. We will be streaming 9am-3pm Central. At www.youtube.com/@SchmidtOcean #AsgardArchaea @schmidtocean.bsky.social @moorefound.bsky.social @texasscience.bsky.social @utmsi.bsky.social

This team are searching for new "Asgard archaea" to sequence. Let's talk about why these bacteria-like organisms are so fascinating, why they're named for Norse mythology, and why looking at them is unlocking a better understanding of our own genomes. Once considered a type of oddball bacteria🦠...

Congratulations to the newly minted Dr. Brittney Voigt! After defending a fantastic thesis spanning work in my lab and the @edwardmarcotte.bsky.social lab.

Integrative Biology at UT is hiring an Evolutionary Biologist! Happy to answer any questions about the position/dept/UT. Come join us! integrativebio.utexas.edu cns.utexas.edu apply.interfolio.com/177547

Really enjoying watching science happen in real time, with @archaeal.bsky.social, @valdeanda.bsky.social, and colleagues live streaming their robot sub data collection from the R/V Falkor off of the coast of Uruguay

Starting at 7pm Central I will be streaming from the bottom of the ocean off the coast of Uruguay! Feel free to join and ask questions. www.youtube.com/@SchmidtOcean

Asgard collaborative expedition begins… Falkor (too) has left Montevideo

My department at UT Austin is looking to hire an Assistant Professor in Evolutionary Biology, broadly defined. Feel free to reach out to me with any questions you may have. apply.interfolio.com/177547

A wonderful collaboration between my lab and Andy Ellington and Edward Marcotte here at UT. We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)

🌍Open call: Junior Group Leader positions! Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery. Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...

Baker Lab 2025 The container is our field gear for the research expedition for Uruguay. sites.utexas.edu/baker-lab/sp...

We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

New: Researchers are broadly rejecting the Trump administration's compact. In faculty votes and student protests, they have mobilized to pressure their universities—to some effect: 6 of the original 9 universities have rejected the compact With @alexwitze.bsky.social and @jennaahart.bsky.social:

Congratulations to this year's cohort of Packard Fellows! @packardfdn.bsky.social Such a great program, especially needed in these times. www.packard.org/insights/new...

So sad to hear the news - John truly was an inspiration to so many, and one of a kind. www.cam.ac.uk/research/new...

So much fun to host @edwardmarcotte.bsky.social at the @biozentrum.unibas.ch and introduce him to the @cellarchlab.com, thanks for a wonderful Discovery Seminar!!

Delightful to finally meet you @edwardmarcotte.bsky.social and hear about your crazy cool science exploring the proteomes of all the diverse beasties on the planet to reconstruct LECA 🧪🌎. Now I see where Caitie gets it from 👨‍🔬👩‍🔬