Elena Sindram, Laura Gámez-Díaz and colleagues @uni-freiburg.de show that LRBA interacts with non-muscle myosin IIA and regulates the #actin #cytoskeleton and #immune synapse formation in #BCells #Lymphocyte #antigen -> link.springer.com/article/10.1...

Philipp Rieche, Marten Exterkate, Arnold Driessen et al show that the #lipid divide between #bacteria and #archaea is not as strict as previously thought as bacterial lipid synthesizing enzymes can use both stereo-forms of glycerol-phosphate. #MembraneBiology -> link.springer.com/article/10.1...

Emmanuel Amzallag, Eran Hornstein and colleagues show that the E3 #ubiquitin ligase MKRN2 maintains granulostasis by preventing the accumulation of misfolding-prone DRiPs into #StressGranules. -> link.springer.com/article/10.1...

See our first June issue! link.springer.com/journal/4431... The cover features work by Daniel Ríos @yosoyden.bsky.social at UNAM in Mexico City and co-workers showing that the #ECM scaffolds interdependent #tissue morphogenesis in #Drosophila. link.springer.com/article/10.1...

Congratulations to Mayra Aguirre-Garcia from Annemarie Meijers lab @unileiden.bsky.social for receiving the EMBO reports poster prize at #EMBOpathogenSignalling for her work "GBP1 recruitment to Mycobacteria-containing vesicles through calcium signalling drives #macrophage lysosomal defenses".

A new review on #evolution is online! Pavithra Venkataraman and Christian Landry @christianlandry.bsky.social discuss a conceptual framework for the joint influence of coding and regulatory mutations in shaping fitness and impacting molecular #evolution. -> link.springer.com/article/10.1...

Attending the GRC conference “Endosomes and Lysosomes in Action Across Cells, Tissues and Disease States” in Andover, NH? www.grc.org/lysosomes-an... Talk to our editor Martina Rembold who is attending the meeting about your work or publishing-related topics! #lysosome #endosome

Lee Armstrong, Yogesh Kulathu @kulathu.bsky.social and co-workers show that MINDY3's EF-hand domain is a novel #ubiquitin binding domain. It not only enables chain-length-dependent deubiquitination but also binds to DNA repair factors RAD23A/B. -> link.springer.com/article/10.1...

Great EMBO YIP @embo.org lecture by Teresa Thurston @thurstonlab.bsky.social @ox.ac.uk at "Pathogen Immunity and Signalling" #EMBOpathogenSignalling. Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs. See also: -> link.springer.com/article/10.1...

Attending the EMBO @embo.org workshop "Pathogen Immunity and Signalling" #EMBOpathogenSignalling in Leiden? meetings.embo.org/event/26-pat... Talk to our editor Achim Breiling who is attending the meeting about you work or publishing-related topics!

A tumour-host feed-forward loop contributes to the growth of chromosomal instability-induced tumours. -> link.springer.com/article/10.1...

The end of a great meeting: Gemma Crupi @magnanilab.bsky.social @icr.ac.uk won the EMBO reports poster prize at #embocancerevolution in Rimini. -> meetings.embo.org/event/26-can... Congratulations!

How can funders rethink research excellence with their communities? New @embo.org guest post shares insights from a workshop bringing researchers together to explore fairer, more inclusive assessment aligned with DORA & @coarassessment.bsky.social principles. Explore the full story 👉 bit.ly/RRA-EMBO

Second May issue is live! link.springer.com/journal/4431... The cover features work by Mateusz Majda @matmajda.bsky.social and Richard S Smith @johninnescentre.bsky.social showing that puzzle cells transform cell geometry into a living record of how leaves grow. link.springer.com/article/10.1...

Hi #EMBOCancerEvolution! Talk to our editor Achim Breiling who is attending the meeting about you work or publishing-related topics!

Kosuke Miyauchi at Center for Integrative Medical Sciences @riken-science.bsky.social and co-workers show that TMPRSS2-induced #Golgi disruption restricts the incorporation of #virus envelope glycoproteins into #virions. -> link.springer.com/article/10.1...

A new review is online! Cynthia Reinhart-King and co-authors tell you all you need to know on cellular mechanometabolism: stimuli and implications. -> link.springer.com/article/10.1...

First May issue is live: link.springer.com/journal/4431... Cover features Simon Unterholzner @simonjunterholzner.bsky.social @unibz.bsky.social and co-workers showing that #brassinosteroids control cell proliferation in the lateral #root cap of #Arabidopsis. -> link.springer.com/article/10.1...

The Hippo paradox! Takahiro Chihara and co-workers show that the #Hippo tumor suppressor pathway triggers non-cell autonomous #tumorigenesis in #Drosophila. link.springer.com/article/10.1... Highlighted by Pooja Rai & Andreas Bergmann: link.springer.com/article/10.1...

Claudio Mauro @unibirmingham.bsky.social and co-workers show that DNA methylation-mediated memory of obesity in CD4 T lymphocytes perpetuates immune dysregulation. -> link.springer.com/article/10.1...

Second April issue is live! link.springer.com/journal/4431... Cover features work by Hwei-Jan Hsu and co-workers, Institute of Cellular and Organismic Biology, Academia Sinica, showing that Wdr4 regulates ribosome biogenesis and intestinal homeostasis via let-7. link.springer.com/article/10.1...

Hypercompetition, score compression and AI co-authorship: a perfect storm for grant success rates. Read Lynns latest column here: link.springer.com/article/10.1...

A new review is online! Philipp Henneke, Sebastian Baasch and co-authors @uni-freiburg.de tell you all about how #cytomegalovirus manipulates myeloid cells to invade tissues. -> link.springer.com/article/10.1...

Our paper (@stoplab.bsky.social), in collaboration with the Nojima lab (@pol2rna.bsky.social @chiheron.bsky.social), on the role of chromatin modifier SETD2 at both ends of the transcriptional cycle, is now published in @emboreports.org 🪅 (1/5) link.springer.com/article/10.1...

Shunya Tsuji, Akio Tsuboi & Eiji Hara and co-workers from Osaka University show that senescence-like cells recruit γδ T cells to drive prolonged #hyposmia after #SARS-CoV-2 infection in mice. -> link.springer.com/article/10.1...

Michel Tremblay @mcgill.ca and co-workers show that PTPN1/PTPN2 inhibition improves NK #cancer therapy by enhancing #IL-2 and mitigating #TGFβ1 responses. -> link.springer.com/article/10.1...

The first April issue is online! link.springer.com/journal/4431... The cover features work by Pierre Cattenoz @unistra.fr @cnrsbiologie.bsky.social showing that NimA promotes cell adhesion at the blood brain barrier of the #Drosophila nervous system. link.springer.com/article/10.1...

🍀🔬📑 Brassinosteroids control cell proliferation in the lateral root cap of the Arabidopsis root @emboreports.org link.springer.com/article/10.1...

100 years of the theory of the gene! In 1926 Thomas Hunt Morgan published "The Theory of the Gene". Read more on Morgan’s gene theory and the rise of modern genetics. By Yongsheng Liu. -> link.springer.com/article/10.1...

Final note, last week we took the proofs out to celebrate 😂

Yay! Our paper is now out @emboreports.org! I posted about it a while back (tinyurl.com/yc7td3px) but the work really improved thanks to the wonderful feedback from three anonymous reviewers 🙏 (1/4)

I am thrilled to share with you our new paper published in @emboreports.org - Led by our fantastic PhD student Loïc Bideau with the help of many lab members. #Platynereis #regeneration #Notch @ijmonod.bsky.social @cnrsbiologie.bsky.social @upcite.bsky.social link.springer.com/article/10.1...

Second March issue is live! link.springer.com/journal/4431... Cover features work by Alla Grishok @bostonu.bsky.social @columbiauniversity.bsky.social on mutual regulation of spermatogenesis-specific #Argonaute proteins and #Insulin/IGF-1 signaling in aging. -> link.springer.com/article/10.1...

NimA promotes cell adhesion at the blood brain barrier of the Drosophila nervous system. -> link.springer.com/article/10.1...

Prepare to defend #evolution! Joel I Cohen on how to protect Darwin’s theory and to help courageous individuals who have challenged attempts to instill creationist material into curricula. Read more here: -> link.springer.com/article/10.1...

Geraldine Seydoux @hhmi-science.bsky.social @jhu.edu and co-workers show that germ granule component PGL-3 undergoes #RNA independent #phaseseparation driven by structured domains that oligomerize and interact with RGG motifs. -> link.springer.com/article/10.1...

The first March issue is online! link.springer.com/journal/4431... The cover features work by Xueliang Zhu, Huijie Zhao and co-workers showing that JHY enables the transition from switchable to fixed ciliary waveforms in #metazoan #evolution. link.springer.com/article/10.1...

Zach Flamholz and I discuss microbial diversity as a foundation for biological AI link.springer.com/article/10.1... in @emboreports.org

Two papers on important roles of the Arp2/3 complex in microglia in the CNS microenvironment by the labs of Jeremy Rotty and Tim Lämmermann @laemmermann-lab.bsky.social @mpi-ie.bsky.social and ZMBE @uni-muenster.de. Read more: link.springer.com/article/10.1... link.springer.com/article/10.1...

What happens when single-author science papers become rare? 🧪 An EMBO Reports Science & Society article explores whether solo publications are being edged out by collaborative #research, and what that means​ for #creativity in #science: https://link.springer.com/article/10.1038/s44319-025-00677-1

In the meantime, the 2nd February issue is live: link.springer.com/journal/4431... The cover features work by Sudha Kumari @sudha-kumari.bsky.social and co-workers showing that #actin waves guide #antigen receptors at the #lymphocyte immunological #synapse. link.springer.com/article/10.1...

Read this @emboreports.org paper here=> link.springer.com/article/10.1...

NELF prevents transcriptional readthrough into DNA replication zones in cancer cells. -> link.springer.com/article/10.1...

See our first February issue: link.springer.com/journal/4431... The cover features work by Tomasz P. Rygiel, Katarzyna Mleczko-Sanecka and colleagues showing that liver sinusoidal endothelial cells scavenge #hemoglobin. -> link.springer.com/article/10.1...

Elena Seiradake @kavlioxford.bsky.social and co-workers @ox.ac.uk @renalucl.bsky.social present crystal structures of the CD177 ectodomain and a CD177-PR3 complex, revealing a major autoantibody epitope. -> link.springer.com/article/10.1...

Liedewij Laan @liedewijlaan.bsky.social and co-workers show that the #GEF Cdc24 and the #GAP Rga2, key regulators of the GTPase Cdc42 in Saccharomyces cerevisiae, exhibit concentration-dependent and synergistic regulation of Cdc42 activity. link.springer.com/article/10.1...

EZH2 directs HER2+ breast cancer progression through the modulation of epithelial plasticity -> link.springer.com/article/10.1...

IRF2 deficiency disrupts #pyroptosis, NK cell interferon-γ production and #resistance to Francisella. -> link.springer.com/article/10.1...

See the second January issue: link.springer.com/journal/4431... The cover shows work by Meghan Ferguson @micro-megs.bsky.social and Annika Guse @annikaguse.bsky.social @lmumuenchen.bsky.social showing symbiont-specific uptake in cnidarian larvae via integrins. link.springer.com/article/10.1...

See also the great News&Views comment by Monica Gobran and @plenart.bsky.social - highlighting all three papers! link.springer.com/article/10.1...