📢 Institut Jacques Monod Seminars 📅 Oct. 7th 📍 Institut Jacques Monod Invited by the @stemdevevo.bsky.social Lab , @canaztekin.bsky.social will present an Institut Jacques Monod seminar on the theme « Signaling centers of appendage regeneration: from single cells to species » ➡️ buff.ly/Nvw4YZn

Very soon !

Day 19 - Depths. blood belly comb jelly (Ctenophora), helmet jellyfish (Cnidaria). Animals in the deep sea are some of the most beautiful, particularly the jellies with bodies like abstract portraits that move ethereally in the abyss. Here are two drawings of jellies you can find in the deep sea.

Me: *checks news* Me, 20 minutes later: *transforms into tiny crab, floats way on jellyfish*

Are digits modified fins, or evolutionary innovations? Read how we tackled this old question from a new angle🧪 A story with @chasebolt.bsky.social, @homeobox.bsky.social and myself, coordinated by @denisduboule.bsky.social from @college-de-france.fr and published in @nature.com today! #InHoxWeTrust

Tortoise/Turtle (order Testudines): Shells of many species of turtles and tortoises are intricately marked and coloured, yet are incredibly perfectly designed by nature to blend precisely with their natural habitats. Superb photos taken by Casey Leone. Top row, from left to right: #turtle #turtles

Predatory tunicates at the Monterey Bay Aquarium #TunicateTuesday #MarineLife #Invertebrates #DeepSea #Megalodicopia #MBARI #MontereyCanyon #Photography #WestCoast

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

There is always room for wonder.

How many chromosomes can an animal have? In our paper out now in @currentbiology.bsky.social we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact. www.cell.com/current-biol...

New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵

Please re-post: Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo... Abstract deadline: 30 September

More on the ancient foundation of animal development. Coyle & King illustrate how core regulatory modules were present in our pre-animal ancestors. The key was not invention, but recycling & new protein interactions. #CellBiology #multicellularity #protistsOnSky www.nature.com/articles/s41...

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

Les espèces classiques de la SVT : se reproduisent 🥱 Les reines des fourmis M. ibericus : clonent des mâles d'une autre espèce 🤯 pour se reproduire avec et créer des ouvrières hybrides 😤 tout en faisant des mâles de leur espèce pour faire des nouvelles reines 💃💃 www.nature.com/articles/s41...

🧠🦈Excited to present our latest work🧠🦈Interested in brain evolution? And shark embryos? Then read on… Our work sheds light on the deep origins of our brain’s most complex regions.

👨‍🔬 Retrouvez Lucas Leclère,chercheur au @biom-banyuls.bsky.social dans l'équipe @cnidevo.bsky.social, dans l’émission "Avec Sciences" sur @franceculture.fr ! Il y parle du fascinant destin des méduses holoplanctoniques. 🎧 Écoutez l’épisode : www.radiofrance.fr/francecultur... @obs-banyuls.fr

Some executioner caspases also have non-apoptotic functions. This study shows that sublethal executioner #caspase activation enhances #hepatocyte proliferation via JAK/STAT3 signaling, revealing a role for executioner caspases in promoting liver #regeneration @plosbiology.org 🧪 plos.io/3JEsH57

Congrats Zoé for this important step !

Our new preprint is out ! We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles. Check it out and please share @igdrennes.bsky.social

Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...

Lovely piece on five model organisms for the origin of animal multicellularity and on the community who studies them. It was a pleasure to make a small contribution.

Summer break prevented me from properly advertising this serie of reviews on the function of cell death during development that I edited. There is still a lot to dig in regarding regulation of apoptosis in vivo ad I hope we managed to illustrate this well www.sciencedirect.com/special-issu...

Mechanosensation and fast reorientation of ciliary structures: Marvin's work on the surprising locomotion capabilities of Trichoplax, an animal without neurons! www.biorxiv.org/content/10.1...

New addition to the spectacular life cycle of Osedax worms: sex of O. japonicus is genetically (not environmentally) determined since larvae show both morphological and transcriptomic signatures of gender. Might help us explain male dwarfism rdcu.be/eCHBe @alicerouan.bsky.social @NorioMiyamoto

www.nature.com/articles/s41... Cool paper by @emmanuelhaillot.bsky.social et al. from Uli Technau's group. @tclebedeva.bsky.social and I were also involved 🙃

How does the alvinellid worm Paralvinella hessleri survive the toxic extremes of deep-sea #HydrothermalVents? A new study shows that it detoxifies its environment by forming orpiment minerals inside cells; this unique #biomineralization is a novel adaptation to toxic environments.🧪 plos.io/3HtVCZ6

My feather cell type paper is finally out! doi.org/10.1111/ede.... We’ve packed a ton of stuff into this paper but I’ll go through some highlights in this thread!

#CNRSinsolite 🔬 L'Institut Jacques Monod ouvre ses portes à l'occasion de deux Visites Insolites du @cnrs.fr 2025 ! 🧬 Tentez votre chance du 25 août au 17 septembre 2025 en répondant à trois questions en lien avec la thématique de la visite choisie ! En savoir plus 🔗 www.ijm.fr/fete-de-la-s...

🌴 Connaissez-vous l’arbre du voyageur ? Derrière ce nom poétique se cache une plante spectaculaire, endémique de Madagascar… et surtout, dotée de graines étonnantes ! Pour tout connaître sur ces graines 👉 https://www.mnhn.fr/fr/arbre-du-voyageur

Vote now in our image competition with the 2025 @mblscience.bsky.social Embryology course! Check out these stunning images and pick your favourite: thenode.biologists.com/vote-for-you... #FluorescenceFriday

Happy to highlight our recent preprint by the amazing Skylar Settles, with her undergrad student, Kathleen. Skylar started with the goal of carefully (& tediously) describing the in vivo cellular environment of planarian stem cells, unusual for their adult pluripotency. 1/6 doi.org/10.1101/2025...

We are excited to highlight our Rising Star Awardee, Dr. Can Aztekin @canaztekin.bsky.social whose work highlighting the importance of oxygen in regulating regeneration is inspiring. #Onetowatch

🐟 Zebrafish (Danio rerio): Clear as glass, zebrafish embryos let you watch organs form in real time. A powerhouse for studying organogenesis and regeneration, they’re also champions of transgenic expression of fluorescent proteins 🌈 image from Gopi Shah 🧪 #ModelMonday #DevBio

For #MosaicMonday this fantastic photo of a mosaic (and a lovely fish 🐟) that was discovered in the submerged ruins of #Roman Baiae. Photo: Parco Archeologico Campi Flegrei

Is the deuterostome clade an artifact??? New paper with first author @anaserrasilva.bsky.social, Laura Piovani, Paschalis Natsidis and project co-led by Paschalia Kapli. www.sciencedirect.com/science/arti...

This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered

Sarre, @alexdemendoza.bsky.social et al. study the evolution of methyltransferases and the roles of cytosine methylation in underexplored eukaryotes, revealing a rich ancestral eukaryotic repertoire and an important role for lateral gene transfer. 🔗 doi.org/10.1093/molbev/msaf176 #evobio #molbio

Remember, the next Polychaete Conference #IPC15 is coming to Frankfurt in 2026! Make sure you save the dates - and in the meantime check out the website for the polychaete-association.com

Evolution’s eye game is wild, but mollusks take it to another level CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates rdcu.be/ezw0t

Latest paper elifesciences.org/articles/107... closes an important cycle in our efforts to study regeneration: week-long recordings allow us to observe the behaviour of cells during the entire course of regeneration in a crustacean leg – bright objects in movie are fluorescent nuclei of cells. 1/6

I believe that over the past ~ two decades, since the breakthrough papers on UHRF1, this is the first reported DNA methylation phenotype of its close paralog, UHRF2 (and not for lack of trying). Congrats to Ambre Bender and Michael Weber on this fantastic study! www.nature.com/articles/s41...

TET enzymes remove #DNAmethylation markers; @ismaelhdeznunez.bsky.social @clark-lab-retina.bsky.social &co show that these enzymes are required for #photoreceptor cells to initiate the genetic program to become rods instead of cones, & for maturation of the #retina @plosbiology.org 🧪 plos.io/3UaVBfl

Cells in a regenerating axolotl limb somehow know their place—but how? In our new paper, we trace the dynamics of positional memory, release open-source code to quantify it, and introduce a theoretical framework for proximalisation. 🧵👇 🔗 www.nature.com/articles/s41... (1/n)

📢 Neuro Evo Devo meeting Virginie Courtier organizes a meeting regarding the latest research on development, evolution and neurobiology using as model organisms birds, fishes, butterflies and Drosophila 📆 Tuesday, August 26th 📍 Institut Jacques Monod Informations and program 🔗 buff.ly/p3qkFLW

Happy to share our last protocol for efficient endogenous gene tagging in Medaka. We hope this will encourage genetic and imaging approaches in other non-conventional fish models. A big thank you to all co-authors, and congrats to the first author Simon Knoblich bio-protocol.org/en/bpdetail?...

Happy to see our latest work out in @molbioevol.bsky.social. We revisit the evolution of 5-methylcytosine across neglected eukaryotic supergroups, establishing an ancestral repressive role silencing genome invaders, both transposons and viral elements👾: academic.oup.com/mbe/advance-... 🧵 1/7

✍️The @stemdevevo.bsky.social Lab contributed to a new article 📖 @bmc.springernature.com 📃 A genome resource for the marine annelid Platynereis spp 🔗 bmcgenomics.biomedcentral.com/articles/10....

An insightful @cp-trendsgenetics.bsky.social perspective on our recent article about the early evolution of genome regulation in animals. www.cell.com/trends/genet... Thank you Omar and @ferdix.bsky.social!