Prof. Maria Dulcetti Vibranovski (Universidade de São Paulo) joins GBE, bringing expertise in genome evolution, chromosome biology, gene regulation and expression evolution, spermatogenesis and reproductive genomics, new gene origination and evolution, and sex chromosome evolution #societyjournal

GBE proudly welcomes seven new Associate Editors to its Editorial Board! These researchers bring vast experience in genomic sciences and evolutionary biology, and will provide a great service to the SMBE community. We will be presenting these colleagues throughout the coming days. #societyjournal

Really excited to see this paper out! We hope it will be a valuable resource for the paleogenomics community, especially given the recent surge in studies using aDNA to infer natural selection. Huge kudos to @anchieri.bsky.social for the outstanding work 👏 #aDNA

@anchieri.bsky.social @cegamorim.bsky.social et al. benchmark the inference of selection with aDNA-like time series datasets, showing that ApproxWF can estimate selection with datasets of ∼100 individuals when selection is strong. 🔗 doi.org/10.1093/gbe/evaf234 #genome #evolution #compbio

Valente et al. examine the impact of gene duplication and loss on the evolution of sperm energetics in mammals - their findings illustrate how metabolic pathways co-shaped by gene duplication and erosion define extant physiological phenotypes. 🔗 doi.org/10.1093/gbe/evaf246 #genome #evolution

Simão et al. analyzed gene expression in two Drosophila species that produce sterile hybrids, with results supporting a role for sex-biased gene and TE expression in reproductive isolation. 🔗 doi.org/10.1093/gbe/evaf247 #genome #evolution #TEsky

The Altai wasn’t just home to Denisovans. 🏔️🧬Ancient DNA revealed unexpected bovine diversity 🦬, including a mysterious yak-like lineage (yak "X") now seemingly lost to time. academic.oup.com/gbe/article/... #MetagenomicsMonday #ancientDNA #aDNA #paleogenomics #zooarchaeology #denisovacave #altai

@michaeltconnelly.bsky.social et al. sequenced 342 Pocillopora coral samples from the Eastern Tropical Pacific, revealing four distinct species; algal symbiont community profiling identified dominant symbionts that varied according to host species. 🔗 doi.org/10.1093/gbe/evaf235 #genome #evolution

@ccasola.bsky.social, A. Owoyemi and @vakirlis.bsky.social test the hypothesis that many noncanonical proteins possess low stability in the cellular environment, finding that noncanonical proteins were enriched for degradation-related features. 🔗 doi.org/10.1093/gbe/evag009 #genome #evolution

Interested in using aDNA time-series datasets to estimate selection? Our study "Assessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data" is now out in GBE! doi.org/10.1093/gbe/... @genomebiolevol.bsky.social @cegamorim.bsky.social

SMBE is calling for nominations for Best Graduate Student Papers of 2025, recognizing outstanding papers in @molbioevol.bsky.social and @genomebiolevol.bsky.social 🗓️ Deadline Feb 27 Articles published in 2025 are eligible. The nominated student must be first author; anyone can nominate authors.

The cover of February's issue of Genome Biology and Evolution features the work of Kosakyan et al. on the evolution of mitochondrial genomes in the Gastrotricha. 🔗 doi.org/10.1093/gbe/evag001 #genome #evolution #mtDNA

@proteinmechanic.bsky.social et al. present the web-based Structome-AlignViewer for evaluating structure-aware alignments through spatial mapping of alignment columns to protein structures, and quantitative confidence scoring. 🔗 doi.org/10.1093/gbe/evag004 #genome #evolution #compbio

#ERGAReads | IChromosome-scale Genomes Show Rapid Diversification and Ancient Gene Flow Among Bear Species 🐻 🔗 doi.org/10.1093/gbe/... @genomebiolevol.bsky.social

@gokcumenlab.bsky.social I really like the spinning-top model for explaining the prevalence of auto-immune conditions!

I’m excited to share a new paper by a super talented graduate-student-now-postdoc. Grateful to work with old and new collaborators! Characterizing a novel Symbiopectobacterium MEX strain at the early stages of establishing a symbiotic relationship url: academic.oup.com/gbe/article/...

Read our new paper in Genome Biology & Evolution to learn more about how sequencing the genome from a 14,000 year old wolf puppy's last meal yielded novel insights into the woolly rhino's extinction: academic.oup.com/gbe/article/... 📷 Mietje Germonpré

the first evol-mut-circle meeting of 2026 happens Tuesday, 20 Jan, 15:00 UTC (8:30 pm India, 10 am EST). Madeleine Oman will present "How Sequence Context-Dependent Mutability Drives Mutation Rate Variation in the Genome" academic.oup.com/gbe/article/... DM me to join the list for meeting info

Pretty cool way to find ancient DNA. I am not sure what's sadder, that this Rhino got eaten or that the animal that ate it died before the meal was digested... https://academic.oup.com/gbe/article/18/1/evaf239/8414728

Pajic & @gokcumenlab.bsky.social synthesize the evolution of VNTRs in mammals, including mutational mechanisms and selective forces driving their evolution, and propose a theoretical framework for their persistence through evolutionary tradeoffs. 🔗 doi.org/10.1093/gbe/evaf250 #genome #evolution

New review from @gokcumenlab.bsky.social led by Petar Pajic on VNTRs. If you’re interested in VNTRs, this is a very nice synthesis. academic.oup.com/gbe/article/...

Gunasekaran, Sicard, Almeida & @symboevo.bsky.social report a novel symbiotic interaction between a leafhopper and a bacterium; they analyse the genome of the bacterium, inferring it is in the early stages of establishing a host-dependent symbiosis. 🔗 doi.org/10.1093/gbe/... #genome #evolution

So proud that this is out 🐺⏳🧬🦏. First paper as a senior author (co-shared with @lovedalen.bsky.social; thanks for a great opportunity) and led by my awesome former MSc student @solveiggudjonsd.bsky.social and a brilliant CPG postdoc @edanalord.bsky.social (1/n) OA: academic.oup.com/gbe/article/...

A woolly rhino genome has been recovered from meat preserved in a frozen wolf pup’s stomach. The 14,400-year-old DNA is helping researchers understand why woolly rhinos went extinct.

In my latest for @arstechnica.com, researchers sequenced a complete woolly rhino genome from a 14,000-year-old bit of meat found in the stomach of a frozen wolf puppy, and it sheds some light on megafaunal extinction. 🧪

Scientists recover genome from woolly rhino eaten by Ice Age wolf reut.rs/4qopUgY

These are the days of miracles and wonder.... 🦣🧬

The recent article on wholly rhino ancient genomics by Guðjónsdóttir, @jcchacond.bsky.social et al. has received plenty of attention in the media. ⬇️ Check below the thread below for some great coverage on this story.

In the stomach of a mummified wolf pup, scientists find DNA from a woolly rhino https://www.newsbeep.com/nz/233753/ Two ancient wolf pups found entombed in Siberian permafrost more than a decade ago are revealing new stories,…

Hey there #wolf 🐺 pup hands off woolly #rhino 🦏 www.livescience.com/animals/land... #wildlife #paleontology

Thank you, Sólveig M. Guðjónsdóttir, @jcchacond.bsky.social & Dr Kamilla Pawłowska for speaking w/me about woolly rhino DNA from a mummified wolf pup! Thank you, @andreatweather.bsky.social, for improving the story! www.scientificamerican.com/article/scie...

Scientists managed to extract a high-coverage genome of an extinct woolly rhino from an undigested piece of its flesh found in the stomach of a permafrost-preserved 14kyo wolf pup. 🧪🏺

A rare sample from a woolly rhinoceroses reveals how the population changed in the lead-up to the species’ extinction go.nature.com/4qWohHb

Step back and think about this…it’s INCREDIBLE We can sequence DNA from an extinct species that’s been dead for thousands of years. Not only that, we can sequence DNA from another extinct species that first extinct species ate as its last meal…to learn about population dynamics of the extinct prey.

Davide Peede & colleagues* (with input from me) have written a review paper on applications of the SMC model academic.oup.com/gbe/article/... We discuss what is the SMC approximation and why it is important, and then discuss many methods that use its machinery to infer various aspects of biology.

Forskare vid @cpgsthlm.bsky.social har analyserat arvsmassa från en 14400 gammal ullhårig noshörning. Arvsmassan kommer från vävnad som hittades i magen på en förhistorisk varg. Studien visar att noshörningarna var genetiskt friska fram till slutet av senaste istiden. www.su.se/nyheter/nyhe...

I mean, honestly, what are people even going to do that can compete with this title? “Genome Shows no Recent Inbreeding in Near-Extinction Woolly Rhinoceros Sample Found in Ancient Wolf's Stomach” academic.oup.com/gbe/article/...

#ERGAReads | The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity 🌈🧬 🔗 academic.oup.com/gbe/article/... @genomebiolevol.bsky.social @unil.bsky.social @embl.org @mpi-bio-fml.bsky.social @univie.ac.at @uab.cat #genomics #genomicdiversity

New publication: "The Golden #Lancehead Genome Reveals Distinct Selective Processes Acting on #Venom #Genes of an Island Endemic #Snake" with Pedro G. Nachtigall from @unioslo-cees.bsky.social & @biovitenskap.bsky.social published in Genome Biology and Evolution @genomebiolevol.bsky.social

Guðjónsdóttir, @jcchacond.bsky.social et al. sequenced the genome of a >14kya old woolly rhino from muscle found inside a permafrost-preserved wolf's stomach. Demographic inference suggests a rapid extinction for the woolly rhino. 🔗 doi.org/10.1093/gbe/evaf239 #genome #evolution #aDNA

Lin et al. assess the impact of sequencing depth when mapping ancient DNA data and in silico modern and ancient-like DNA data, showing that depths >100X fail to yield stable heterozygosity estimates, and leave ~4% of the genome uncovered. 🔗 doi.org/10.1093/gbe/evaf251 #genome #evolution

Palacios, Capdevilla & Albalat identified 48 putative metallothioneins from 30 myriapod species; differences between diplopod and chilopod MTs likely reflect distinct metal uptake, retention, and excretion strategies associated with their ecology. 🔗 doi.org/10.1093/gbe/evaf248 #genome #evolution

The recent Review on the applications of 'omics tools to the evolutionary ecology of bees is the focus of January's GBE Highlight. From Genomes to Hives: ‘Omics Perspectives on Eusocial Evolution and the Ecology of Bees 🔗 doi.org/10.1093/gbe/evaf249 📸 Amro Zayed #genome #evolution #bees

Möllmann, @eckartstolle.bsky.social et al. report the first genome assembly for the European orchard bee and investigate its epigenomic architecture to find evidence for the limited role of methylation in gene regulation in Hymenopterans. 🔗 doi.org/10.1093/gbe/evaf224 #genome #evolution

Check our review in GBE about SMC-based methods! I wish I had a review like this when I started my PhD

In a new GBE Review, @david-peede.bsky.social et al. overview the SMC model and extensions, discuss examples of discoveries made with the help of SMC-based inference, and comment on the assumptions, benefits, and drawbacks of various methods. 🔗 doi.org/10.1093/gbe/... #genome #evolution #compbio

Brenman-Suttner & @amrozayed.bsky.social review how 'omics tools provide insights into the molecular basis of bee eusociality and adaptation, and allow us to address urgent challenges facing bee conservation due to anthropogenic change 🔗 doi.org/10.1093/gbe/evaf226 📸 Amro Zayed #genome #evolution

@emilhaegglund.bsky.social @lionelguy.bsky.social et al. employed sequence-based and structure-based search methods to investigate the origin of the anammoxosome, the sole known energy-producing organelle in bacteria, and its key enzyme. 🔗 doi.org/10.1093/gbe/evaf244 #genome #evolution #microbesky

Kulikov, @ikeririsarri.bsky.social @fonamental.bsky.social et al present a 529.6 Mb chromosome-scale genome for the redlip blenny (scaffold N50 = 23.7 Mb; BUSCO = 97.06%). Annotation identified 18,927 protein-coding genes. 🔗 doi.org/10.1093/gbe/evaf242 📸 Evan D’Alessandro #genome #evolution

Nachtigall et al. present a genome assembly and annotation for the golden lancehead, a critically endangered venomous snake endemic to the Queimada Grande island of Brazil; demographic history indicates a stable population over the last 10k years. 🔗 doi.org/10.1093/gbe/evaf243 #genome #evolution