@isaacmtzu.bsky.social
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Computational biology of non-coding genome. Postdoctoral researcher | University of Toronto
reposted by
Kate Sรกnchez
3 days ago
Mexico's first woman ref in a men's World Cup match! ๐๐๐
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reposted by
Genome Biology and Evolution
about 1 month ago
Martinez-Ugalde et al. used comparative transcriptomics to show that argonaute protein exWAGO is part of an evolutionarily conserved pathway for LTR retrotransposon regulation. ๐
doi.org/10.1093/gbe/evag117
๐๏ธ Laura Fabiola Espinosa Juรกrez / Isaac Martinez-Ugalde
#genome
#evolution
#celegans
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reposted by
bioRxiv Bioinfo
2 months ago
Recursive Repeat Extender (RRE): A recursive approach to automatically extend repeat element models
https://www.biorxiv.org/content/10.64898/2026.04.14.718546v1
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reposted by
Alessandro Scacchetti
8 months ago
RNAs outside of cells?! How did they get there? (Thread coming soon ๐)
www.biorxiv.org/content/10.1...
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Pseudouridine selects RNAs for extracellular transport
RNAs move through the extracellular space to transmit information between cells, including mammalian neurons, yet how specific RNAs are channeled into these extracellular routes is unknown. Using geno...
https://www.biorxiv.org/content/10.1101/2025.10.28.685156v1
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reposted by
bioRxiv Genomics
7 months ago
Improved spike-in normalization clarifies the relationship between active histone modifications and transcription
https://www.biorxiv.org/content/10.1101/2025.11.25.690627v1
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reposted by
bioRxiv Evolutionary Biology
8 months ago
Programmed DNA elimination was present in the last common ancestor of Caenorhabditis nematodes
https://www.biorxiv.org/content/10.1101/2025.10.23.681605v1
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reposted by
bioRxivpreprint
8 months ago
Argonautes and small RNAs associated with nematode programmed DNA elimination
https://www.biorxiv.org/content/10.1101/2025.10.23.684123v1
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Thrilled to share our preprint on the ancestral function of the secreted Argonaute exWAGO ๐งฌ๐
www.biorxiv.org/content/10.1...
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Comparative transcriptomics reveals an extracellular worm argonaute as an ancestral regulator of LTR retrotransposons.
Safeguarding the genome from non-self elements is essential for reproduction, development, and ageing. One of the major threats to genome integrity is Transposable Elements (TEs), which can be postโtr...
https://www.biorxiv.org/content/10.1101/2025.09.22.674508v2
9 months ago
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reposted by
bioRxivpreprint
10 months ago
The impact of rearing environment on C. elegans: Phenotypic, transcriptomic and intergenerational responses to 3D enriched habitats
https://www.biorxiv.org/content/10.1101/2025.09.07.674770v1
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reposted by
Gavin Woodruff
10 months ago
! Evolution of developmental bias explains divergent patterns of phenotypic evolution in two nematode clades
www.pnas.org/doi/10.1073/...
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Evolution of developmental bias explains divergent patterns of phenotypic evolution in two nematode clades | PNAS
Rates of phenotypic evolution vary across traits, and these evolutionary patterns themselves evolve. Understanding how development contributes to s...
https://www.pnas.org/doi/10.1073/pnas.2507529122
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reposted by
bioRxiv Evolutionary Biology
11 months ago
Emergence and stabilisation of a neo-Y chromosome in nematode species with rare males
https://www.biorxiv.org/content/10.1101/2025.07.25.666552v1
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reposted by
eLife
11 months ago
๐งฌJune's most-read Genetics paper independently validates previous research showing that
#CElegans
can inherit learned pathogen avoidance:
buff.ly/HQgprLp
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reposted by
TREnD
12 months ago
#TREnD2025
virtual day is here!! First talk starting now! ๐ฅณ
add a skeleton here at some point
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reposted by
Kyriaki Neophytou
about 1 year ago
Super excited to see our work shared with the scientific community! We know
#Argonaute
proteins can be extracellular, but can they be transferred to recipient cells and can they function? Happy reading!
add a skeleton here at some point
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