Detection of a sequence feature for recursive splicing https://www.biorxiv.org/content/10.64898/2026.04.13.717821v1

Whole-genome 3D architectural screen reveals modulators of brain DNA structure https://www.biorxiv.org/content/10.64898/2026.04.15.718501v1

Ancestral Genome Reconstruction. https://www.biorxiv.org/content/10.64898/2026.04.16.718917v1

Histone H1 Variants Regulate Neurodevelopmental Transcriptional Programs in Autism with 16p11.2 deletion https://www.biorxiv.org/content/10.64898/2026.04.15.718677v1

Ancestral chromatin state constrains the functional landscape of bivalent domains in mammalian spermatogenesis https://www.biorxiv.org/content/10.64898/2026.04.14.718508v1

Decoding TF-Specific Predictability in Cross-Species Binding Site Inference https://www.biorxiv.org/content/10.64898/2026.04.14.718438v1

Age-associated increases in inter-individual gene expression variability across human tissues https://www.biorxiv.org/content/10.64898/2026.04.14.718522v1

Contrasting transcriptional responses and genetic determinants underlie Zymoseptoria tritici adaptation mechanisms to simulated host defense environments https://www.biorxiv.org/content/10.64898/2026.04.14.718361v1

fastVEP: A Fast, Comprehensive Variant Effect Predictor Written in Rust https://www.biorxiv.org/content/10.64898/2026.04.14.718452v1

Complete Telomere-to-Telomere Assembly of the Y Chromosome in the Chinese Quartet https://www.biorxiv.org/content/10.64898/2026.04.13.718326v1

Long-read MitoScope reveals tissue-resolved somatic mitochondrial variation and landscape of nuclear-embedded mitochondrial sequences https://www.biorxiv.org/content/10.64898/2026.04.13.718259v1

CanVAS: A Harmonized and Imputed Canine Variant Atlas1 https://www.biorxiv.org/content/10.64898/2026.04.13.718238v1

Single-Cell and Tissue-Specific CRISPR Editing Analyses Unveil New Insights to Off-Targets and Translocations https://www.biorxiv.org/content/10.64898/2026.04.13.718115v1

Spatial transcriptomic landscape of the Ciona adult brain: functional zonalisation and cellular composition in a sessile chordate brain and a novel insight into neural gland function https://www.biorxiv.org/content/10.64898/2026.04.13.718160v1

MetaMuse: A Multi-Agent AI System for Biomedical Metadata Curation and Harmonization https://www.biorxiv.org/content/10.64898/2026.04.12.718044v1

A deterministic computational kernel encoded in the human genome https://www.biorxiv.org/content/10.64898/2026.04.12.718009v1

Lineage-specific CK2α deletion reshapes the transcriptome of hematopoietic stem cells toward an immune-primed state https://www.biorxiv.org/content/10.64898/2026.04.10.717787v1

Effects of introgressed Neanderthal alleles on present-day brain morphology https://www.biorxiv.org/content/10.64898/2026.04.14.718380v1

A Reference Genome for the Critically Endangered Philippine Eagle (Pithecophaga jefferyi), the National Bird of the Philippines https://www.biorxiv.org/content/10.64898/2026.04.12.717985v1

Somatic mutation landscape revealed by non-invasive iPSC derivation from urine cells https://www.biorxiv.org/content/10.64898/2026.04.11.717904v1

Scalable genotyping in fixed transcriptomes resolves clonal heterogeneity via single-cell sequencing https://www.biorxiv.org/content/10.64898/2026.04.11.717967v1

Living by the sea: chromosome-scale genome assembly and salt gland transcriptomes provide insights into ion regulatory mechanisms in the saline-tolerant mosquito Aedes togoi https://www.biorxiv.org/content/10.64898/2026.04.09.717544v1

A segmental duplication-mediated deletion leads to neocentromere formation in orangutans https://www.biorxiv.org/content/10.64898/2026.04.09.717302v1

EVEE: Interpretable variant effect prediction from genomic foundation model embeddings https://www.biorxiv.org/content/10.64898/2026.04.10.717844v1

Genomic insights into bacterial isolates dominating honeypot ant crop microbiomes reveal metabolically distinct Fructilactobacillus sp. https://www.biorxiv.org/content/10.64898/2026.04.09.717501v1

Palaeogenomics-informed inferences of European dog admixture enables scalable dingo conservation https://www.biorxiv.org/content/10.64898/2026.04.08.717357v1

Flanking DNA sequences determine DNA methylation maintenance in proliferation, cancer and aging https://www.biorxiv.org/content/10.64898/2026.04.09.717557v1

Suppression of upstream ORF translation is not a widespread mechanism of translational stimulation by yeast helicase Ded1 https://www.biorxiv.org/content/10.64898/2026.04.10.717766v1

A Joint Promoterome-Proteome Atlas Highlights the Molecular Diversity of Human Skeletal Muscles https://www.biorxiv.org/content/10.64898/2026.04.08.717200v1

Genomic insights into polyketide toxin synthesis and algal symbiosis using high-quality genome sequences of the early divergent hexacorallian genus Palythoa (Cnidaria, Zoantharia) https://www.biorxiv.org/content/10.64898/2026.04.08.717340v1

Aimea gen. nov. defines a novel plant-associated yeast genus in Microbotryomycetes with three novel species https://www.biorxiv.org/content/10.64898/2026.04.08.717246v1

Eco-physiological and transcriptomic plasticity of Dianthus inoxianus in response to drought https://www.biorxiv.org/content/10.64898/2026.04.08.702570v1

Genomic epidemiology of the 2017-2023 outbreak of Mycoplasma bovis sequence type ST21 in New Zealand https://www.biorxiv.org/content/10.64898/2026.04.07.717125v1

Conditional genome-wide associations reveal novel genes https://www.biorxiv.org/content/10.64898/2026.04.08.717258v1

An introgressed galectin-like protein is a candidate driver of the human tropism in the intestinal parasite Cryptosporidium https://www.biorxiv.org/content/10.64898/2026.04.07.716958v1

Benchmarking SNP-Calling Accuracy Against Known Citrus Pedigrees Reveals Pangenome Advantages Over Linear References https://www.biorxiv.org/content/10.64898/2026.04.07.716967v1

Over-representation of sperm-associated deleterious mutations across wild and ex situ cheetah (Acinonyx jubatus) populations https://www.biorxiv.org/content/10.64898/2026.04.07.716683v1

Systemic mutagen exposures reported by normal kidney cell genomes https://www.biorxiv.org/content/10.64898/2026.04.07.716715v1

Transposable element disruption of a second thyroglobulin-like gene confers Vip3Aa resistance in Helicoverpa armigera https://www.biorxiv.org/content/10.64898/2026.04.06.716841v1

Genomic consequences of admixture in an experimentally founded sand lizard population https://www.biorxiv.org/content/10.64898/2026.04.07.714984v1

Comparative genomics of Cadophora luteo-olivacea reveals a divergent lineage, conserved functional repertoires, and strain-level variation in pathogenicity https://www.biorxiv.org/content/10.64898/2026.04.07.716880v1

Socially regulated genes are spatially hyperconnected to enhancers in the ant brain https://www.biorxiv.org/content/10.64898/2026.04.08.717219v1

Genomic indicators of gene function: A systematic assessment of the human genome https://www.biorxiv.org/content/10.64898/2026.04.08.717348v1

Deep-Plant: a supervised foundation model for plant regulatory genomics https://www.biorxiv.org/content/10.64898/2026.04.06.716755v1

Detecting context-dependent selection on cancer driver genes with DiffDriver https://www.biorxiv.org/content/10.64898/2026.04.06.716771v1

Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes https://www.biorxiv.org/content/10.64898/2026.04.07.717039v1

Sample barcoding-associated technical variation in probe-based single-cell RNA sequencing https://www.biorxiv.org/content/10.64898/2026.04.06.716804v1

Temporal shifts in polygenic traits track major epidemics in Western Eurasia https://www.biorxiv.org/content/10.64898/2026.04.07.717059v1

Global genomic diversity of the selfing nematode Caenorhabditis tropicalis correlates with geography https://www.biorxiv.org/content/10.64898/2026.04.05.716573v1

Strategy Sets the Scene: Genetic architecture of linalool resistance in Botrytis cinerea https://www.biorxiv.org/content/10.64898/2026.04.05.716576v1