Join us next week for #DevPres to hear 3 of our PI fellows talk about the environment & evolution 14 January 15:00 GMT/UTC With talks from @ethanewe.bsky.social, @maxfarnworth.bsky.social & @sonyawiden.bsky.social, chaired by @pritiagarwal.bsky.social. us02web.zoom.us/webinar/regi... #DevPres

And if you can't make it, we at CSH Protocols have put together a collection of reviews and protocols for work on Xenopus! Guest edited by Hazel L. Sive. Link below.

Modern Xenopus research uses this system to study #devbio, genetic diseases, biomechanics, and cell biology. If you want hands-on experience, register now to the CSHL Cell & Developmental Biology of Xenopus: Gene Discovery & Disease meetings.cshl.edu/courses.aspx... Deadline: January 16, 2026

Link to collection: cshprotocols.cshlp.org/site/misc/ma...

Modern Xenopus research uses this system to study #devbio, genetic diseases, biomechanics, and cell biology. If you want hands-on experience, register now to the CSHL Cell & Developmental Biology of Xenopus: Gene Discovery & Disease meetings.cshl.edu/courses.aspx... Deadline: January 16, 2026

This is our last post of the year. Hope you have a wonderful holidays. Remember, good science only comes from a well-rested mind. We will see you again next year! #MicroscopyMonday #Christmas Image: 3D Christmas spheroids Staining: Phalloidin Photo credit: Postdoc Hoang Anh Le, @ucl-cdb.bsky.social

Thank you for all the engagements. Have a wonderful holiday. We will see you again next year 👋

This is our last post of the year. Hope you have a wonderful holidays. Remember, good science only comes from a well-rested mind. We will see you again next year! #MicroscopyMonday #Christmas Image: 3D Christmas spheroids Staining: Phalloidin Photo credit: Postdoc Hoang Anh Le, @ucl-cdb.bsky.social

The 2026 Santa Cruz Developmental Biology Meeting website is LIVE!!! Go see the incredible list of scientists who will be speaking at the meeting next summer! (...and check the site early next year for info on registration and abstract submission.) scdb2026.sites.ucsc.edu

Meeting Alert! Santa Cruz Developmental Biology Meeting! 👇 @socdevbio.bsky.social @insdb.bsky.social @bscb-official.bsky.social @isdb.bsky.social @bsdb.bsky.social @ascbiology.bsky.social

Check out Part II of our special collection celebrating the centennial of the discovery of the organiser. From classical developmental biology, to tissue mechanics, and organoid and plant development, we've got it all!

❗PREPRINT ALERT❗ doi.org/10.64898/202... The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.

Congrats to the leading author @agrigas.bsky.social!

❗PREPRINT ALERT❗ doi.org/10.64898/202... The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.

Check out Part II of our special collection celebrating the centennial of the discovery of the organiser. From classical developmental biology, to tissue mechanics, and organoid and plant development, we've got it all!

Check out the summary written by our Editor in Chief, Professor Roberto Mayor: www.sciencedirect.com/science/arti... And if you missed it, here is the link to Part I of the collection: www.sciencedirect.com/special-issu...

We're in love with this cover image! 🧡 Part II of our Special Collection celebrating the Centennial of the Discovery of The Organiser is here. This issue focuses on the work presented at the Centennial Symposium at the University of Freiburg in September 2024: www.sciencedirect.com/journal/cell...

One of our favourite activities each year too.

Predicting and Designing Red Fluorescent Protein Variants Using Sequence-to-Function Machine Learning Models by Yufeng Zhao and team: www.biorxiv.org/content/10.6...

Looks like a really useful tool!

#SpatialTranscriptomics STcompare github.com/JEFworks-Lab... Test your gene of interest if it is differentially spatially patterned (r, p, s)🤠 Spatial correlation Spatial fold change Control for spatial autocorrelation @jef.works bioRxiv 2025 www.biorxiv.org/content/10.1...

Vertebrates can use entirely different mechanisms to generate its anterior and posterior dorsal tissue. In this thorough review from the lab of Lance Davidson, different morphogenetic events are compared between the front and the back in a developing embryo. Check it out: doi.org/10.1016/j.cd...

Check out this work from @yuritakahashi.bsky.social that reveals reciprocal interactions between cell migration and fate specific to drive collective cell invasion. And follow Yuri at the same time

Hi bsky! How do cells coordinate fate with migration during development? 🐣 Turns out EMT doesn't just drive cell behaviour changes... it actively primes BMP signalling competence, creating a reciprocal coupling that drives collective invasion! (@bensteventon.bsky.social lab) tinyurl.com/2ncc8zap

Pleased to say that Jonas Hartmann (bs-less) and I have finally released DySTrack (“diss track”) - Dynamic Sample Tracking. It’s a Python-based, modular tool that brings smart microscopy to everyday imaging on commercial systems. Preprint: www.biorxiv.org/content/10.6... [1/6]

You can also find the Github code here: github.com/WhoIsJack/Dy...

Do your samples move out of view? Tired of manually adjusting the stage? Introducing DySTrack developed by @zimengwu33.bsky.social and Jonas Hartmann from UCL, a tool that can be integrated into modern microscopes to automate the tracking of moving samples. #MicroscopyMonday doi.org/10.64898/202...

Do your samples move out of view? Tired of manually adjusting the stage? Introducing DySTrack developed by @zimengwu33.bsky.social and Jonas Hartmann from UCL, a tool that can be integrated into modern microscopes to automate the tracking of moving samples. #MicroscopyMonday doi.org/10.64898/202...

We have one of those too, by Lizhong Liu and Jun Wu. doi.org/10.1242/dev....

Stunning poster. Yo @cellsdev.bsky.social, can we have our version too?

This makes a fantastic poster to compare the differences between models of development.

Primate amnion development In this Review, Nikola Sekulovski, Amber E. Carleton, Chien-Wei Lin and Kenichiro Taniguchi (@taniguchi-lab.bsky.social) discuss recent advances in primate amnion development doi.org/10.1242/dev....

Decoding the role of SOX2 in retinal progenitor competence This Research Highlight showcases the work of Fuyun Bian, Kimiasadat Golestaneh, Emily Davis, Abdullah Khan, Issam Al Diri and colleagues: journals.biologists.com/dev/article/...

Great to see this published: Fitting dynamical landscape models to single-cell data, creating interpretable maps of cell decision making & developmental logic Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions www.pnas.org/doi/10.1073/...

🎄 Day 4 of the 24 Days of Development ✨🧬 In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁  doi.org/10.1016/j.yd...

We have just published a tribute to John Gurdon, reflecting on his scientific legacy and the profound influence he had on generations of developmental biologists. The piece is available open access in Nature Communications: www.nature.com/articles/s41...

Principles in mechanical engineering can be applied to study biomaterials, such as the notochord. In this theoretical study, Curcio et al investigated how the different ways of notochord stacking affects its structural rigidity. A staircase stacking seems to be better! doi.org/10.1016/j.cd...

New preprint alert‼️‼️ Beautiful images!

We are excited to share our new preprint: SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids. www.biorxiv.org/content/10.64898/2025.12.01.691499v1

✨A gut feeling you’ll love this one 🐛 The anterior midgut of a Drosophila melanogaster 🪰larva puts on a confocal glow show! 🟢 Adult midgut progenitors 🔴 Actin 🔵 Nuclei 📸Image by Sapna Krishnakumar #FluorescenceFriday #Microscopy #DevBio

For this week #FluorescenceFriday, we'll be treated with one of our favourite animal models 🐸 . Here is a Xenopus laevis embryo imaged with a Lightsheet microscope showing macrophage migration. Purple🟣 = ectoderm nuclei, Red🔴 = macrophages. 📹: Hoang Anh Le, postdoc in the Mayor lab, UCL.

Stunning @anhhle2702.bsky.social 😍

For this week #FluorescenceFriday, we'll be treated with one of our favourite animal models 🐸 . Here is a Xenopus laevis embryo imaged with a Lightsheet microscope showing macrophage migration. Purple🟣 = ectoderm nuclei, Red🔴 = macrophages. 📹: Hoang Anh Le, postdoc in the Mayor lab, UCL.

How do cytokines shape immune cells? We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells. More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/ #ImmunoSky

I have more live imaging of actin in B cells from this week for this #FluorescenceFriday

Registration deadline 20th Dec! We have generous travel grants for early career researchers! April is a beautiful time to visit China!

Microglial CLEC7A restrains amyloid beta plaque pathology in a mouse model of Alzheimer's disease Fascinating study from the lab of @lukensjohnr.bsky.social alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Think about craniofacial biology in sunny California😎! Don't forget to submit an abstract for the 2026 GRC Craniofacial. Many talk slots available from abstract selections. Deadline for talk abstracts 14 Dec, coming soon.... ☠️🐭🐟🐸🧬 #craniofacial #genetics #neuralcrest www.grc.org/craniofacial...

Tissue-resident macrophages are doing more than just protecting from infection. In this interesting paper, René Fernando Abarca-Buis et al shows that they can promote reepithelialization and blastema formation and regulate the maturation of chondrocytes. Check it out here: doi.org/10.1016/j.cd...

Three more weeks to sign up!