Calling all microscopy enthusiasts!

We love #zebrafish too!

Calling all microscopy enthusiasts!

#DBfeature #DBreview Potentials of RNA biosensors in developmental biology by Ehsan Pashay Ahi, Mehran Khorshid www.sciencedirect.com/science/arti...

This would be so cool!

orthogene bioconductor.org/packages/rel... Map your genes of interest across >700 species Can do many:many bioRxiv 2026 www.biorxiv.org/content/10.6...

Three-dimensional quantitative tissue clearing reveals differences in osteovascular niche of aged and young human mesenchymal stromal cells

We love #zebrafish too!

An interesting paper from the Kojic lab shows that ankrd1a - a stress responsive gene is consistently unregulated near damaged site in the ❤️ in zebrafish. Loss of ankrd1a leads to an increase in dedifferentiating cells. Check it out here: doi.org/10.1016/j.cd...

🗓️Key dates: Early-bird deadline – 8 May 2026 Abstract deadline – 12 June 2026 Final registration deadline – 24 July 2026 🎤An amazing line up of speakers and organised by some of your fav dev bio scientist ;) @wellcometrust.bsky.social @bsdb.bsky.social @biologists.bsky.social

‼️The registration for the Development Journal Meeting 2026 - Human Development: Stem Cells, Models, Embryos is now open. This year marks a collaboration between @dev-journal.bsky.social and the Human Developmental Biology Initiative consortium. www.biologists.com/meetings/dev...

Early bird registration deadline is 8th of May 2026!!

‼️The registration for the Development Journal Meeting 2026 - Human Development: Stem Cells, Models, Embryos is now open. This year marks a collaboration between @dev-journal.bsky.social and the Human Developmental Biology Initiative consortium. www.biologists.com/meetings/dev...

Congratulations to Xi Yang, Yun Zhou & co for winning our 2025 Outstanding Paper Prize. Their paper addresses broad & long-standing questions about how cells become new stem cell populations in the fern Ceratopteris. Read the Editorial: doi.org/10.1242/dev.... Paper: doi.org/10.1242/dev....

‼️Calling all researchers‼️ We are in the process of preparing for the 2029 ISDB conference in India, and we want to hear from you, especially ECRs in the field. Help us design an inclusive and scientifically exciting event by completing this survey by April 13: forms.office.com/e/w1qbNF6KvL Thank you

Do take this survey and let us know your thoughts!

We want to hear from you. Help us design an inclusive event for everyone by filling in this short form that won't take you more than a few minutes.

‼️Calling all researchers‼️ We are in the process of preparing for the 2029 ISDB conference in India, and we want to hear from you, especially ECRs in the field. Help us design an inclusive and scientifically exciting event by completing this survey by April 13: forms.office.com/e/w1qbNF6KvL Thank you

✨ This Xenopus 🐸 tadpole came to #FluorescenceFriday serving eye-conic energy 👀 Stage 39 eye stained with a whole rainbow: 💙 DAPI | ❤️ Acetylated tubulin | 💚 RPE | 🩵 Rhodopsin | 💜 Pax6. 📸 Image from Jian Sun.

An interesting paper from the lab of Edgar Krötzsch showing the potential contribution of tissue-resident macrophages in the regeneration of punched holes in mouse's ear. Depleting macrophages with clodronate liposomes reduced regeneration and induced cartilage formation. doi.org/10.1016/j.cd...

This is pretty cool!! Congratulations to all authors.

Very happy to share this study from our group and colleagues now out in Science! We found that in zebrafish, before the immune system is mature, gut epithelial cells perform immune functions by producing the cytokine IL-22 to shape the microbiota to promote early life gut function #Zebrafish #Gut

Open Call for Associate Editor of our official journal Cells and Development @cellsdev.bsky.social. Our current group of Associate Editors: www.sciencedirect.com/science/arti...

Be our Associate Editor!! It's fun 💃

Open Call for Associate Editor of our official journal Cells and Development @cellsdev.bsky.social. Our current group of Associate Editors: www.sciencedirect.com/science/arti...

That's crazy! 🫨🫨🫨

Planarian innate immunity blocks transgene expression This Research Highlight showcases work by Leonard Drees @auricle1.bsky.social, Jochen Rink and colleagues at @mpi-nat.bsky.social. journals.biologists.com/dev/article/...

And it’s a wrap… the end of an era and what an era it was at igc and @gimminstitute.bsky.social. @pdncambridge.bsky.social and @gurdoninstitute.bsky.social here I come. Brace yourselves 😉!

Some say development is guided by forces. While the role of chemistry in dev bio is undeniable, growing evidence has pointed out the significant contribution of physics too. Chowdhury et al discuss how forces shape normal and cancer stem cells and the clinical applications. doi.org/10.1016/j.cd...

Looking for a home for your immune cell biology paper? Our Academic Editor, Sophie Acton (@actonlab.bsky.social) handles articles on this topic so send your article our way. There are lots of reasons to choose JCS – find out more: journals.biologists.com/jcs/pages/re... #immunology #immunecells

A movie from 9 years ago and I've never noticed the actin wave inside these cells until now 😱 It looks like a cluster of actin filament moving from 1 place to the other and pushing the cell membrane out to form protrusions. Reminds me of an ocean undercurrent. How interesting! #FluorescenceFriday

Scientific conferences can be a bore. Can jokes liven them up? Science Careers speaks with ecologist @stefanomammola.bsky.social about the power of humor to enhance science communication. https://scim.ag/4uCVf1N

Happy #FluorescenceFriday! Here is a micrograph of a section of a neonatal 🐭🫁 showing showing cilia in 🟡 and nuclei in 🔵. Cilia are marked by the protein Arl13b. 🔬 by postdoctoral fellow Sam Hack 👩‍🔬 🧪

Mechanically sensitive ion channels are being recognised as one of the major players in cell migration. It makes sense since cell migration is a rather physical process. Check out this review to learn more!

Many ion channels eg. TRP, Piezo are mechanically sensitive, meaning they can be activated/deactivated by mechanical stimuli such as membrane curvature or substrate stiffness. In this thorough review from the Mayor lab, they discuss how these channels regulate cell migration. doi.org/10.1016/j.cd...

Negative results are just as important as positive ones. They inform future investigations of what to focus on, saving resources. In this study, Wang et al showed that the protein LSM14A is dispensable for spermatogenesis and male fertility in mice. Check it out: doi.org/10.1016/j.cd...

A fantastic conference! Register now. It's FREE! Stunning cover image too 💙

YEN 2026 registration is now live! Join us for the 2026 YEN conference on the 15th of June at the Francis Crick Institute, London, UK. Sign up now to attend and submit your poster/abstract: forms.gle/2HQEmZgEi4hP... Abstract submission deadline is 15 May. Stay tuned for more information!

Applications open for the Stem Cell & Developmental Biology Early Career Symposium being held September 23-25, 2026 in Seattle, WA. This joint symposium is a collaboration between @alleninstitute.org, @isscr.org and @socdevbio.bsky.social Application Deadline: May 1. bit.ly/4p98dkv

Gisela Cairo @giselacairobaza.bsky.social, Muhammad Haseeb @muhammad-haseeb.bsky.social, Soni Lacefield @lacefieldlab.bsky.social & team find that the MOS-MAPK pathway regulates polar body fate in mouse oocytes. journals.biologists.com/jcs/article/... journals.biologists.com/jcs/article/...

This looks like another fantastic resource for the gene and spatial transcriptomic folks (and beyond)!

Very happy to see this out. 👏 @yinanwan.bsky.social Bogdan Bintu and team. Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...

Final morning at #gfe2026, with Hans Clevers delivering the @isdb.bsky.social lecture. Hans brings together #devbio, stem cells and medicine, using organoid models of the small intestine to study human disease, explaining why signalling and the microenvironment are important for stem cell activity.

No better way to start the 4th and final day of #GfESEBDDSDB2026 #GfE2026 than with the International Society for Developmental Biology (@isdb.bsky.social) - Cells & Development Lecture by Hans Clevers (@hansclevers.bsky.social) on "Organoids model human disease: 3D and 2D"

#Question: This may sound like I'm crazy but has anyone experienced immersion oil solidifying or getting stickier after light exposure? Until recently I noticed the oil suddenly gives off a lot of autofluorescence after ~10 mins of imaging, becomes thicker. Have to wipe constantly, really annoying.

Best buddies? More like budding buddies 🪼👯‍♀️✨ Six stages of asexual budding in Hydra to generate new genetically identical individuals (clones). 🟣: collagen 🟢: stem cells. 📸 Image by Ben Cox #FluorescentFriday

Fancy a fresh preprint for Friday? When we were first getting involved with single molecule FRET, there weren't any standard protein molecules that suited our applications to help us develop our pipeline. So we built some! A universal protein ladder for FRET. 🧵 1/

New JCS snapshot - Redefining colocalization analysis with a novel phasor mixing coefficient Owen Puls @owfpuls.bsky.social presents the key findings from their recent JCS paper with Teng-Leong Chew @scopeshifu.bsky.social @hhmijanelia.bsky.social and team. journals.biologists.com/jcs/article/...

Earth is now warming at a rate of around 0.35 ºC per decade, fresh analysis finds. go.nature.com/4boG2tH