We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do? Well this review by Claudio Stern may give you the answers: doi.org/10.1016/j.cd...

We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do? Well this review by Claudio Stern may give you the answers: doi.org/10.1016/j.cd...

In this intriguing paper published from the lab of @amartinezarias.bsky.social , they looked at the effects of size on morphology, tissue composition, and gene expression of gastruloid development. They found that AP elongation dynamics is size-dependent! Check it out here: doi.org/10.1016/j.cd...

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

In this intriguing paper published from the lab of @amartinezarias.bsky.social , they looked at the effects of size on morphology, tissue composition, and gene expression of gastruloid development. They found that AP elongation dynamics is size-dependent! Check it out here: doi.org/10.1016/j.cd...

Epithelial-to-mesenchymal transition or EMT is an integral part of development in animals. In this beautifully illustrated review from the lab of Magali Suzanne, they describe and compare and contrast the cellular mechanism of EMT across the different model organisms. doi.org/10.1016/j.cd...

Our September issue cover is now online. You can check out the issue here: www.sciencedirect.com/journal/cell...

In 2019, Anna Jost & @jencwaters.bsky.social reviewed best practices for validating quantitative #microscopy methods & discuss strategies to avoid unconscious bias in imaging experiments rupress.org/jcb/article/... 📕 In #Reproducibility & Best Practices in Cell Biology: rupress.org/jcb/collecti...

Led by the awesome @dzelmanoff.bsky.social

We are grateful to all our sponsors who made the V4SDB Meeting 2025 in 🇸🇰 possible and accessible, specifically Visegrád Fund, @biologists.bsky.social, @isdb.bsky.social, @cellsdev.bsky.social, @devdynamics.bsky.social, MUNI SCI, Allgene, BRIX, LABO-SK, and Merck Life Science. Thank you!

Early Career Opportunity Mentorship & career development, access to world-class facilities, and a collaborative, supportive environment. We are particularly interested in researchers in Synthetic Dev. Biol. Mechanobiology and AI . #AcademicJobs #EarlyCareerResearcher #UCL #DevelopmentalBiology

For decades, living embryos were the favourite tool to study development. However, their complexity hindered precise dissection of many processes. This comprehensive review provides a comparison between embryos and the power of gastruloids, opening up a new wave of dev bio. doi.org/10.1016/j.cd...

A cryosection from an embryo stained for the neural crest (🟠) using HCR, and DAPI (⚪). Can you guess what embryo this is? #FluorescenceFriday Image credit: Ines Fernandez Mosquera, PhD student at @ucl.ac.uk

Many phenotypes from cells on plastic dishes just don't seem to translate to cells in vivo, particularly isolated primary cells. @raimonsunyer.bsky.social et al discussed how cells mechanically adapt, and the different ways we can mitigate this in this very helpful review: doi.org/10.1016/j.cd...

What are the physics behind lumen formation? In this interesting and interdisciplinary review, Guillaume Salbreux et al described the physical laws from osmotic pressure to electrical potential that govern this biological process. Check it out here: doi.org/10.1016/j.cd...

A Summer reading recommendation: new primer in @dev-journal.bsky.social explains how dynamical systems theory unlocks the logic of developmental patterning Everything from bistable switches & oscillators to phase portraits & more with Python code to explore journals.biologists.com/dev/article/...

If you happen (…!) to be interested in what fascinates me about science and brain evolution and what I am up to, click here: doi.org/10.1242/dev.... Thanks to @dev-journal.bsky.social and @biologists.bsky.social for the interview 🙏

What are the physics behind lumen formation? In this interesting and interdisciplinary review, Guillaume Salbreux et al described the physical laws from osmotic pressure to electrical potential that govern this biological process. Check it out here: doi.org/10.1016/j.cd...

For something as classic as the Spemann-Mangold organizer first discovered in amphibians, the existence of such an organiser in mammals remains elusive. In this thought provoking review by Kate Mcdole et al, they discuss the evidence for and against such organiser in mouse. doi.org/10.1016/j.cd...

For something as classic as the Spemann-Mangold organizer first discovered in amphibians, the existence of such an organiser in mammals remains elusive. In this thought provoking review by Kate Mcdole et al, they discuss the evidence for and against such organiser in mouse. doi.org/10.1016/j.cd...

A classical neural crest migration. Even if the movie is a little bit shaky, their migration is still somehow mesmerising. It must be the stripes! 🤔 #fluorescencefriday Movie by Kai Weissenbruch

Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)

Can someone please add some beats 🎵🎵 to this video, we beg!

This is so cool! A good way for early career scientists to put your name out there and network too! Beautiful images are always eye catching. Register and we would love to see them too at ISDB!

✨Development meets design in this embryonic chameleon lung 🫁 🦎. Smooth muscle swirls 🟣 and branching tips and cartilage 🟢 come together in reptilian lung morphogenesis. Image taken by @drkatiegoodwin.bsky.social 🔬🧪 #FluorescenceFriday #DevBio

Got stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...

Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch

Out now! Our very first [email protected], an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️ www.cell.com/developmenta...

Our interdisciplinary @embo.org @biologists.bsky.social workshop on Biophysical and Molecular Mechanisms of Animal Homeostasis and Repair will take place in beautiful Haining, China, 6-10 April 2026. Exciting line up of international speakers! Register now: meetings.embo.org/event/26-hom...

1000% YES !!! Also works for cancer, immunology and every other cellular process: differentiation, adhesion, migration, proliferation, survival etc. Cell biology is cool, but it's like studying plants without their soil. I wish more studies would try to put their findings in perspective of the ECM

Interesting review about the role of ECM in development!

Maybe it's time we rethink the idea that development is a cell centric process? In this beautiful review, María-del-Carmen and @stramerlab.bsky.social discussed how the ECM underlies and influences many morphogenesis processes from wing unfolding to mammary gland development. doi.org/10.1016/j.cd...

Maybe it's time we rethink the idea that development is a cell centric process? In this beautiful review, María-del-Carmen and @stramerlab.bsky.social discussed how the ECM underlies and influences many morphogenesis processes from wing unfolding to mammary gland development. doi.org/10.1016/j.cd...

A cryosection immunofluorescence image of a Xenopus embryo showing fibronectin in 🔵, DAPI in ⚪, and Sox9 - a marker of the neural crest in 🟠. Image credit: Kai Weissenbruch from UCL #FluorescenceFriday #devbio

AKAP14 is of those genes that is highly expressed, yet when knocked down by 60% even in a mouse model shows no apparent effects on the organism, no effects on meiotic progression, sperm count, motility and morphology. How weird?Check out this intriguing paper here: doi.org/10.1016/j.cd...

Continuing with the theme of organiser biology, Alexandra Neaverson and Benjamin Steventon discussed in this beautifully illustrated review the idea that "neural specification and patterning occur before organiser formation" in Xenopus, zebrafish, chick, and mouse. doi.org/10.1016/j.cd...

Check out this insightful review by Alfonso Martinez Arias et al where they show how studying the organiser in amphibian embryos helps us understand the development of the body axis in mammalians, and the use of gastruloids to study the Primitive Streak. doi.org/10.1016/j.cd...

This comprehensive review by Manuel Zúniga-García and Juan Rafael Riesgo-Escovar focuses on the evolutionarily conserved fos gene family in different species of invertebrates (🪰,🪱). The authors argued that fos genes were coopted from stress responses to development. doi.org/10.1016/j.cd...

Our June cover is here. This image shows SALL1 protein (green) in a slice section of mouse embryonic external genitalia. New research shows that SALL1 is involved in tubulin acetylation and is important for urethral masculinization. doi.org/10.1016/j.cd...

🎉We’re grateful for the support of @isdb.bsky.social and @cellsdev.bsky.social, who will sponsor the ISDB-C&D Lecture by Gage Crump at the #V4SDB2025 Meeting! #devbio 👉Join us in Slovakia this September: v4sdb2025.img.cas.cz 👉Registration deadline: 31 July 2025 event.img.cas.cz/registration...

Quintay alumni meet-up at the #ICDB2025 meeting in Puerto Rico 🇵🇷 Always great to meet with the Latin American community working in developmental biology around the world 😃 @devbioquintay.bsky.social @mayorlab.bsky.social

🫶 @isdb.bsky.social @devbioquintay.bsky.social @mayorlab.bsky.social

Extremely honored to receive this prize from @socdevbio.bsky.social, which recognizes not only my love for developmental biology, but the extremely online I am 🧪 (protect science, protect people, viva la dev bio!)

One our postdocs, Kai Weißenbruch, just won the Prize for Best Talk at the Cambridge-London Cell Motility conference for his talk on Frictiotaxis - how cells migrate toward regions of higher friction. This video shows a cell repolarises itself in a uniform friction channel. doi.org/10.1038/s414...

A fantastic review written by Jan Stundl and Marianne E. Bronner on the development of the neural crest. The paper explores how neural crest interacts with their tissue, the genes involved in their development, and their differentiation identity. Check it out: www.sciencedirect.com/science/arti...

Register to this super interesting workshop in mechanobiology of tissue morphogenesis and disease. A wide variety of model organisms will be discussed, from fly to frogs to mice. Register now. www.unia.es/estudios-y-a...

Rosettes are cell-scale structures found in epithelial tissue. This unique structure allows for a dynamic bio-mechanical adaptation during development and morphogenesis. In this review, Neahring et al describes the interesting facets of rosettes found in various organs. doi.org/10.1016/j.cd...

We are very proud to announce @johannaivaska.bsky.social as the recipient of the Biennial Finnish Science Award, given by the Finnish Ministry of Education & Culture. Johanna was described as a distinguished researcher with pioneering work in cell biology. Warmest congrats from all of us, boss!

A new review exploring the concept of a living substrate in the context of collective migration in development, where living cells serve as substrate for other cells to migrate on.

1/I'm excited to share my review with CSHL exploring the concept of neighbouring cells as substrate to guide the collective migration of other cells. We tend to focus on cell-matrix interactions, but forget that within tissue, cell-cell interactions exist. cshperspectives.cshlp.org/content/earl...