Schubeler Lab
@schubelerlab.bsky.social
π€ 357
π₯ 43
π 14
Congrats Francesca !
add a skeleton here at some point
6 days ago
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reposted by
Schubeler Lab
FMI science
26 days ago
Our Open Day for Novartis was a great success! π Many
@novartis.bsky.social
colleagues joined us today to explore our science, meet our researchers & enjoy food trucks. Huge thanks to all volunteers and everyone who stopped by β hereβs to more connections and collaborations!
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Iconic!
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28 days ago
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Schubeler Lab
Alexandra Bendel
29 days ago
I am happy to finally share this preprint of my PhD project in
@guillaumediss.bsky.social
lab at the FMI in Basel. We used ddPCA to map the genetic architecture of the entire human bZIP interaction network.
www.biorxiv.org/content/10.1...
Thanks to all our co-authors for the great collaboration!
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The genetic architecture of the human bZIP family
Generative biology holds the promise to transform our ability to design and understand living systems by creating novel proteins, pathways, and organisms with tailored functions that address challenge...
https://www.biorxiv.org/content/10.1101/2025.08.21.671354v1
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We all look forward to the Batki lab at FMI !!!!
add a skeleton here at some point
28 days ago
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Excited to share our latest preprint.
www.biorxiv.org/content/10.1...
. Lead by Lukas, we investigated multiple ways of assessing a TF's sensitivity to chromatin based on genome-wide binding profiles. The developed methods allowed us to quantify chromatin sensitivity across tested TFs.
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A novel deep learning-based framework reveals a continuum of chromatin sensitivities across transcription factors
The genome-wide binding of many transcription factors (TFs) depends not only on the presence of their recognition motifs, but also on the surrounding chromatin context. This raises the question of how...
https://www.biorxiv.org/content/10.1101/2025.08.11.669605v1
about 1 month ago
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Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity.
www.sciencedirect.com/science/arti...
.
about 2 months ago
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reposted by
Schubeler Lab
FMI science
10 months ago
What a night! The FMI year-end party had it all: an inspiring speech from our director, a delicious dinner buffet, a hilarious meme contest, and our traditional cake showdown. Here's to a fantastic 2025 ahead! π₯π
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