Studying gene ends is becoming even more fascinating! Curious why? Read our News & Views "Transcriptional readthrough progresses from incidental byproduct to therapeutic opportunity" inspired by the recent publication by Podszywałow-Bartnicka and @karlaneugebauer.bsky.social @natsmb.nature.com

Our paper (@stoplab.bsky.social), in collaboration with the Nojima lab (@pol2rna.bsky.social @chiheron.bsky.social), on the role of chromatin modifier SETD2 at both ends of the transcriptional cycle, is now published in @emboreports.org 🪅 (1/5) link.springer.com/article/10.1...

Interested in antisense oligonucleotides? Check our story about downstream-of-gene ASOs (DG-ASOs)! Together with the Roche Innovation Center we identified transcription termination windows of protein-coding genes as ASO target regions. link to BioRxiv: www.biorxiv.org/content/10.6...

Very excited about this one - it is definitely worth remembering that 3' end processing and transcription termination are distinct processes and play crucial roles in gene expression 🧬

HIRING! STOP lab is looking for a Research Assistant (Technician) with experience in protein expression and purification. Job & project description and how to apply here: euraxess.ec.europa.eu/jobs/367610

🚨 New preprint from our labs (STOP lab @stoplab.bsky.social & Nojima lab @pol2rna.bsky.social @pyrolyn.bsky.social)! We've been digging into how chromatin remodeler SETD2 controls the start and end of transcription 👇 www.biorxiv.org/cgi/content/... (1/5)

Honored to receive an award from @polskaakademianauk.bsky.social in Poznań for the best 2024 publication led by a PhD student. Our study published in @narjournal.bsky.social highlights a key marker defining gene ends — helping improve genome annotations. Read more 👉 academic.oup.com/nar/article/...

"I have been prepared for evil, for greed, for cruelty, for injustice – but I did not anticipate that the people in power would also be such huge losers." 🤷🏻‍♀️ www.theguardian.com/commentisfre...

Do you know where transcription of a gene actually stops? Hint: it is not the annotated gene end. In our new paper in Nucleic Acids Research we argue that phosphorylation on threonine 4 of RNA Pol II CTD is a marker of transcription termination in animals... 🧵 academic.oup.com/nar/advance-...

Great news & strategic decision @donald-tusk.bsky.social @andrzej-domanski.bsky.social: 500 mln top-up for🇵🇱research @ncngovpl.bsky.social in 2025! Strength. basic research is the best way to drive INNOVATION and INVEST in the FUTURE of 🇵🇱&🇪🇺 A frontline country can do it - what's your gov's excuse?

Coming soon 🫡