🔬 #ColorectalCancer evades #immunotherapy using a dual barrier: A study by #IRBBarcelona & @cnag-eu.bsky.social reveals how metastatic colorectal tumours block the immune system through two complementary mechanisms. 📰 @natgenet.nature.com ➡️ bit.ly/49BJaC0 #IRBScience @batllelab.bsky.social 🧪

1/17 🧵 🙌Thrilled to share our first hard-core immunology paper out today in Nature Genetics! 👇 ➡️We unravel how TGFβ suppresses the innate and adaptive immune system in microsatellite stable colorectal cancer (MSS CRC). Very proud of the team and efforts behind it. www.nature.com/articles/s41...

Could understanding how #cancer cells talk to their neighbours help stop the disease? Johanna Joyce, a regular at #VIBConf, will uncover these new ways to predict, prevent, and treat cancer. Join #THPT25 before 26 Nov and decode the therapies that outsmart cancer: vibbio.tech/3Le9oAr #tumorbiology

At the Oncode Annual Conference 2025. Fantastic Meeting. Thanks for the invite. Catching up with many colleagues and friends. www.oncodeinstitute.nl/events/oncod...

Our recent Cancer Discovery study (Centonze et al.) shows that within hours, metastatic CRC cells switch from an EMP1⁺ invasive state to an LGR5⁺ stem-like program, highlighting that Plasticity is a dynamic, regulated cell-state decision #Bluetorial below👇🏼 #KRAS #Plasticity #ColorectalCancer

Registration for Cancer Cell Plasticity closes on Monday 03 November! Join us online to explore the fundamental mechanisms that control cancer cell plasticity at multiple biological levels: eacr.org/conference/c...

🙌🏼 What a fantastic meeting this was! Congrats to everyone who contributed! #EESOrgan @events.embo.org 🔝 A huge thank you to the organizers for the invitation, and for putting together such a memorable conference. 📸 A remarkable aspect was seeing together five generations of Clevers’ Lab!!

📣 Last chance to register for the EACR virtual conference on Cancer Cell Plasticity You’ll gain new insights into fundamental mechanisms controlling cancer cell plasticity as well as innovative approaches to target them ➡️https://eacr.org/conference/cancercellplasticity2025 @helloeacr.bsky.social

Our recent Cancer Discovery study (Centonze et al.) shows that within hours, metastatic CRC cells switch from an EMP1⁺ invasive state to an LGR5⁺ stem-like program, highlighting that Plasticity is a dynamic, regulated cell-state decision #Bluetorial below👇🏼 #KRAS #Plasticity #ColorectalCancer

➡️ This important video was missing from yesterday’s #Bluetorial. CRC organoids under treatment with KRAS inhibitor RMC-9945, rapidly acquire a LGR5+ cancer stem cell-like phenotype, allowing them to bypass KRAS inhibition, and eventually resume growth. Centonze et al., in #CancerDiscovery #AACR

➡️ This important video was missing from yesterday’s #Bluetorial. CRC organoids under treatment with KRAS inhibitor RMC-9945, rapidly acquire a LGR5+ cancer stem cell-like phenotype, allowing them to bypass KRAS inhibition, and eventually resume growth. Centonze et al., in #CancerDiscovery #AACR

🧵1/17 📣Thrilled to share our latest study just out in Cancer Discovery! ➡️ aacrjournals.org/cancerdiscov...

Lab Celebrations are in order. More news to come

🏆 El lliurament dels Premis Dia del Biòleg 2025 de @biolegscat.bsky.social tindrà lloc demà 25 d'abril a les 16:30 h al COACB. Enhorabona a tots els guardonats! Entre ells, @batllelab.bsky.social, de l'#IRBBarcelona! 🔴 Segueix la cerimònia  en directe aquí: https://f.mtr.cool/egtmfleqvu

Estic molt agraït pel reconeixement rebut. Em sap greu no haver pogut assistir a l’acte de lliurament del premi i a la celebració del Dia del Biòleg. Afortunadament, l’equip hi ha pogut ser present en representació.

Un placer y un honor dar la 28a Lección Conmemorativa Teófilo Hernando. Amigos, colaboradores y científicos a los que respeto y admiro entre los ponentes anteriores.

It’s a pleasure to present our work at CRG’s annual symposium. Many good friends and colleagues around.

🗣️«Estamos empezando a entender cómo se genera la #metástasis y a ser capaces de prevenirlas y eliminarlas cuando ya se han producido». 🗨️ @batllelab.bsky.social #DebatesCaixaResearch

En Sevilla, en las Jornadas conjuntas CIBERONC CIBER_OBN. @ciberisciii.bsky.social

🗣️Debate #CaixaResearch: “La incidencia de #CáncerdeColon aumenta entre los jóvenes" Con @batllelab.bsky.social y @tonigabaldon.bsky.social (@irbbarcelona.org), Angélica Figueroa (INIBIC) y Elena Élez (@vhio.bsky.social#CaixaResearch:#CáncerdeColon  🗓️ Miércoles 19 febrero 🕖 19 h 💻 online ➡️ https://tinyurl.com/bdda8tsr 🧪

Hello everyone on Bluesky! 🧪 We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond. Read more: www.embo.org/about-embo/m...

🧪 We are #hiring! 🔵 #Postdoctoral Fellows: @batllelab.bsky.social#hiring! Stefanie Wculek 🔵 Personnel Administration Expert 🔵 #FlowCytometry Technician 🔵 Public Procurement Officer 🔵 Programme Secretary ➕ℹ️ here ➡️ https://s.mtrbio.com/vmyqtfohpj #IRBJobs #Jobs #PostdocJobs #ScienceJobs

👉 Debate CaixaResearch “La incidencia de cáncer de colon aumenta entre los jóvenes” Ilusionada por compartir debate con @batllelab.bsky.social y @tonigabaldon.bsky.social 📅 Miércoles 19 de febrero de 2025, a las 19 h. Apúntate aquí👇👇👇 bit.ly/3E5vHoq

About to give the Keynote Lecture at the The #KSMetastasis25 @KeystoneSymp on Tumor Microenvironment: Metastasis and the Host. The location at Banff is impressive. Thank you Manuel Valiente and Julio Aguirre-Ghiso for the invitation!

Big day today for Maria Salvany! Defence about to start!

🌟Keystone Cancer Immunotherapy conference 2025 🌟 #KSCancerImmune25 Speaker Highlight #1 Dr. Carl June, the father of CAR T-cell therapy and 2024 #BreakthroughPrize winner will share critical advances in cancer immunology in his talk “Cell Therapies: Current State of the Art”.

What practical measures can we take to help break the glass ceiling for women in cancer research? Listen to episode 10 of The Cancer Researcher Podcast for an insightful discussion with three expert guests including @johannajoyce.bsky.social: magazine.eacr.org/how-to-break...

🌟Keystone Cancer Immunotherapy conference 2025 🌟 Speaker Highlight #2 at #KSCancerImmune25: Dr. Ton N. Schumacher @nkinl.bsky.social will discuss how T cells detect tumors in “Dissecting T Cell Recognition of Cancer.” Don’t miss his cutting-edge immunology insights!

On the move! Nice Landing!

#Organoid #Starterpack #1 is now full (go.bsky.app/RmXgs6d). Time for #Organoids #2/2: go.bsky.app/JVA5H2a Already many great new arrivals & finds such as @batllelab.bsky.social, @saurlab.bsky.social & more!

📢 We are #hiring! 🟠 Postdoctoral Fellows @batllelab.bsky.social, Patrick Aloy 🟠Research Assistant/Bioinformatician @bbglab.bsky.social 🟠 Research Officers: #Bioinformatics/ Biostatistics, #Histopathology 🟠 Public Procurement Officers 🟠 Academic Officer ➕ℹ️here➡️http://bit.ly/3MR4wO8 #IRBJobs 🧪

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We have an Open PostDoctoral Position in the Lab @IRBBarcelona.bsky.social 📢 Project on Tumour Immunology in collaboration with Ido Amit (Weizmann Institute of Science) and Holger Heyn (CNAG) ➡️ recruitment.irbbarcelona.org/jobs/5229393...

We have an Open PostDoctoral Position in the Lab @IRBBarcelona.bsky.social 📢 Project on Tumour Immunology in collaboration with Ido Amit (Weizmann Institute of Science) and Holger Heyn (CNAG) ➡️ recruitment.irbbarcelona.org/jobs/5229393...

Next week in London: Mechanobiology Shaping Life. The deadline for registration is tomorrow, 26/11. iop.eventsair.com/msl2025/

📢 We are #hiring a #Postdoctoral fellow in Tumor Immunology to join our #ColorectalCancer Laboratory (@batllelab.bsky.social)! Apply by 5 December ➡️ tinyurl.com/3nte4crh #IRBJobs #Postdoc #PostdocJobs #ScienceJob #Jobs 🧪

📢 Open POST-DOCTORAL POSITION @IRBBarcelona.bsky.social in Tumour Immunology📢 ➡️ recruitment.irbbarcelona.org/jobs/5229393...

Pls RT: Are you studying the multifaceted MAPK pathway? We would love to hear about your exciting research! Abstract Deadline 👉16.12.2024 for the #virtualmeeting on "Drugging and regulating the #MAPKpathway" organised with @EACRnews with @Boehringer eacr.org/conference/boe…

We’ll be presenting on the Second Day of #BarcelonaBiomed Conference organized by Angel R Nebreda (@IRBBarcelona.bsky.social), Clare Isake (ICR_London) & @mmalumbres.bsky.social

Just one day left for the #BarcelonaBiomed Conference "Molecular Determinants of #Cancer Therapy Resistance"! 🗓️ 18-20 Nov, 2024 #Barcelona 🤝 Angel R Nebreda (#IRB), Clare Isake (ICR_London) & @mmalumbres.bsky.social (VHIO), with @batllelab.bsky.social and a long list of speakers. ➡️bit.ly/4dBTSYI