📺 Sortim al TN de TV3! Encara no coneixeu l'últim estudi del CNAG i @irbbarcelona.org? Descobrim com el càncer colorectal s'escapa de la immunoteràpia fent servir una doble barrera ⬇️ 🗣️ Entrevistes: @esanchosuils.bsky.social, @hoheyn.bsky.social i Ana Henriques 🎙️Us ho explica la Marta Catafal

5/17 To understand the immune landscape at single-cell resolution, @hoheyn.bsky.social and @paulanietog.bsky.social from @cnag-eu.bsky.social led an extensive scRNA-seq + TCR-seq analysis of tumor-infiltrating lymphocytes (TILs) and myeloid cells in models of metastatic CRC under treatment.

🚀New study published in @natgenet.nature.com! 🔝Researchers from CNAG and @irbbarcelona.org uncover how, via a hormone called TGF-β, metastatic colorectal cancer evades immunotherapy using a dual barrier, a discovery that could lead to more effective treatments 🔗 www.cnag.eu/news/colorec...

🌍Yesterday, our PhD student @tmontsay.bsky.social from the Functional Genomics Team presented his poster at #EMBOMobileGenome on 'A Comprehensive Annotation of Conserved Protein Domains in Human Endogenous Retroviruses' 🙌 Excellent work and insightful discussions! @annaesteveco.bsky.social #CNAG

🚀 We’re hiring! Join our team and help decode the genome to improve health and life quality: ▪️General Manager ▪️Post-doctoral Fellow ▪️Accounting Officer ▪️Communication Internship ▪️Grants Manager ▪️Senior Procurement & Public Tenders Officer 👉https://www.cnag.eu/jobs #Jobs #Barcelona #Empleo #CNAG

🚀 Unveiling the secrets of cattle and sheep mites! 🐑 A new study in PLOS Pathogens, with CNAG’s collaboration, reveals how the mite Psoroptes ovis resists treatments commonly used to control infections, paving the way to more sustainable livestock 📎 www.cnag.eu/news/reveali... #Cattle #Genomics

La #recercaUB, publicada a la revista Journal of Biomedical Science, la lidera @jordillorensub.bsky.social, catedràtic de la Facultat de Medicina i Ciències de la Salut i investigador de @ubneuro.bsky.social i de #IDIBELL. A l'estudi han participat investigadors del @cnag-eu.bsky.social.

#PCBCommunity |👂El @cnag-eu.bsky.social participa en un estudi liderat per la @ub.edu i @idibell.bsky.social que identifica els mecanismes genètics implicats en la degradació del sistema vestibular de l’ #oïda, clau per mantenir l’equilibri i la capacitat auditiva mitjançant la #seqüenciació d’ARN.🧬

🌍 Shaping rare disease research in Europe! @erdera.bsky.social just turned one year old, and we celebrated with the first General Assembly, sharing scientific advances and lived experiences 💜 At CNAG, we’re excited about the progress to come in #RareDiseases 🔗https://loom.ly/VXpdiqQ #HorizonEU

🚀La recerca catalana bat rècords! Els centres de recerca del @www.pcb.ub.edu arriben als 84M d'euros d’inversió al 2024, un 20,8% més que al 2023 El CNAG, l'@irbbarcelona.org, l'@ibecbarcelona.eu i l'IBMB, al capdavant del hub científic 📎 www.pcb.ub.edu/la-recerca-p... @recercauniscat.bsky.social

🏆 A tribute to genetics! 🧬 A few days ago, American scientist Mary-Claire King received the Princess of Asturias Award for Scientific Research for identifying the gene responsible for hereditary breast and ovarian cancer, a discovery that changed medicine forever 📎

🚀New advances in hearing loss! 👂Researchers from @ub.edu and @idibell.bsky.social, in collaboration with CNAG, identify the genetic mechanisms that reveal the early steps in hearing loss 🧬Our team has contributed to the RNA sequencing and analysis for this study 📎 www.cnag.eu/news/identif... #ICTS

🌟 Great news! @erdera.bsky.social and #GDI are joining forces to accelerate rare disease research and improve diagnosis across Europe, both initiatives that CNAG is proud to be a partner of 📎 erdera.org/news/erdera-... #RareDiseases #CNAG #Europe #Genomics @horizoneu.bsky.social #1MGenomes

🚀Another project takes off: Genoma de la Cohorte IMPaCT (Go-IMPaCT)! 🎯The goal is to advance precision preventive medicine in Spain. CNAG will be one of the coordinators, contributing to sequencing, data processing, and data management 📎 www.cnag.eu/projects/gen... @ciberisciii.bsky.social #CNAG

📢Save the date: Open Session on rare diseases! 🗓️October 30, 09:00–11:20 CET A free online event, part of the 2nd General Assembly Meeting of @erdera.bsky.social, where we will explore our first year leading #RareDisease research 👉Register here: erdera.org/event/erdera... #CNAG #ERDERA

🙌100+ genomes and counting! 🧬At CNAG, we’re really proud to be part of this amazing initiative, contributing to species conservation by sequencing and assembling their genomes, creating maps that guide protection efforts #Genomics #Biodiversity #HorizonEurope #CNAG @catbiogenoma.bsky.social #ICTS

#PCBCommunity |🧬El @batllelab.bsky.social de @irbbarcelona.org, amb @mamartirenom.bsky.social del @cnag-eu.bsky.social, descobreix que en el #càncer colorectal amb la mutació de l’oncogèn #KRAS, la pressió del tractament pot redirigir els estats cel·lulars en lloc d'eliminar-les. 🔬 👉 tuit.cat/IAkSn

🚀We’re hiring! Join CNAG and be part of the future of genomics in a leading center based in Barcelona Discover our our current openings: ▪️General Manager ▪️Post-doctoral Fellow ▪️Accounting Officer ▪️Communication Internship 👉Apply now: www.cnag.eu/jobs #Jobs #ICTS #ICTSNews #Empleo #Hiring

🚨Save the date: the 14th CNAG Symposium on Genome Research is coming up! Over 10 leading speakers & real-world success stories, from hereditary and colorectal cancers to leukaemia, breast cancer & beyond! 🗓️16 December 📍Parc Científic de Barcelona, Spain 👉 Register now: www.cnag.eu/events/14th-...

🚨New advances in colorectal cancer! Why do some colorectal cancers resist KRAS-targeted therapies? 🔝Our new study in Cancer Discovery discovery reveals the answer, and opens the door to more effective treatments. By @mamartirenom.bsky.social (CNAG) & @irbbarcelona.org 🔗 www.cnag.eu/news/study-r...

💎High-quality DNA matters! A study by UK National Measurement Laboratory and CNAG tested 4 DNA extraction protocols for long-read sequencing 🔬Results: DNA quality and method directly impact the detection of key genetic variants and the success of the research 👉 cnag.eu/news/ensurin... #Genomics

🔝Really proud of our top-notch researchers! 🌍 6 of our PhDs are ranked among the world’s top 2% most influential scientists in Stanford’s 2025 list, in recognition of their global research impact and excellence in genomics @stanfordpress.bsky.social @elsevierconnect.bsky.social #TopScientists #CNAG

🚨We’re hiring! Join CNAG and be part of our mission to advance genomics and improve people’s health 🔎We’re looking for a Grants Manager and a Communication Intern to strengthen our team 👉Apply now: www.cnag.eu/jobs #Jobs #Hiring #CNAG #Communication #Barcelona #Empleo

#PCBCommunity |🧬 El @cnag-eu.bsky.social revela el paper del gen #MYC en la progressió agressiva de la #leucèmia linfocítica crònica.🔬 Les troballes ofereixen noves perspectives sobre quins pacients tenen més risc i apunta cap a possibles estratègies de #tractament personalitzat. 👉 tuit.cat/UrD2b

💜Every year, 2.3 million women are diagnosed with #BreastCancer worldwide At CNAG, we are pioneering genomics, studying the genetic drivers of tumours, enabling early detection, and supporting clinical decisions 💪All against breast cancer #cancerDeMama #noslotomamosapecho #WorldBreastCancerDay

🧬Don’t miss @pascual-reguant.bsky.social at the @embl.org Conference 'Spatial Biology: The Melting Pot'! 🗣️Our Spatial Genomics Team Leader will present on colorectal malignancy transformation from cell to tissue 📅17/10 | 11:00–11:15 📎 www.embl.org/about/info/c... #EMBLSpatialBiology #ESSB2025

👉This week, we welcomed the students of the Master in Genetics and Genomics, a programme run in collaboration with CNAG and the University of Barcelona (@geneticsub.bsky.social) 🧬They explored our Sequencing Unit and Computing Cluster, discovering how genomics and data drive research #Talent #CNAG

🚨Webinar alert! Today, our Functional Genomics Team Leader, @annaesteveco.bsky.social, will discuss the value of RNA-seq & long-read genome and methylome data in rare disease diagnosis 🗓️ 11:00 CEST rwth.zoom.us/meeting/regi... By Next Generation Sequencing Competence Network #RareDiseases

📢New advances on Chronic Lymphocytic Leukaemia! 🧬A study led by CNAG’s Biomedical Genomics Group, published in @frontiersin.bsky.social, shows that MYC, a gene controlling cell growth, drives tumour development & supports disease progression 📎 www.cnag.eu/news/cnag-di... #CLL #CancerResearch

👉 Last week, CNAG joined the 3TR Annual Project Meeting! 🗣️ Ivo Gut presented the Data Management WP, while @ivoleist.bsky.social, Manuel Rueda and Sergio Medrano showcased the 3TR data warehouse, centralising clinical and multi-omics data across 7 immune-mediated diseases to study therapy responses

💜 Want to help shape the future of rare disease research? Apply now for the #EURORDISOpenAcademy on Scientific Innovation & Translational Research Always a pleasure to welcome participants from @eurordis.bsky.social at CNAG 🗓️25–28 May 2026 ttps://go.eurordis.org/OASchools2026 @erdera.bsky.social

🚀The #ASHG Annual Meeting kicks off today! 🗣️Our director, Ivo Gut, will give a Lightning Talk on “Going the Extra Mile to Understand Chronic Lymphocytic Leukemia” and take part in a session on interpreting human variation in cancer genomics & pharmacogenomics #ASHG2025 @geneticssociety.bsky.social

💙Today is #WorldArthritisDay, raising awareness of rheumatic and musculoskeletal diseases affecting millions worldwide At CNAG, we support this cause through initiatives such as #DocTIS, developing new therapeutic strategies for immune-mediated inflammatory diseases #RMDreams #WAD2025 #Arthritis

🌟Calling all single-cell enthusiasts! Join the Autumn School for Single Cell-ers, organised by Gulbenkian Institute for Molecular Medicine (GIMM) next 20-24 October 🗣️Helena Crowell from CNAG’s Spatial Genomics Team will be speaking! gimm.idloom.events/autumn-school @helucro.bsky.social #SingleCell

🎬 Meet Daniele Dell’Aglio, WP3 leader at Aalborg University, who explains how HEREDITARY uses semantic data integration to connect hospitals and researchers across Europe. 🔒Securely and without exposing sensitive data. ▶️ Watch the full interview:

💜 Even better news from the #Unicas_Hackathon! 5️⃣ families have finally received a diagnosis after 48 hours of collaboration among international experts A huge step forward for #RareDiseases and, most importantly, for these children Proud to be part of this initiative! @sjdhospitalbarcelona.org

🧬 Imagine a shared genomic infrastructure across Europe! That’s exactly what we’ve begun to design at CNAG through the EASIGEN-DS project Yesterday, our Director Ivo Gut shared our vision and challenges with ELIXIR, Europe’s life sciences infrastructure #Genomics #Innovation @elixir-europe.org

🌟Great news! This year, the #NobelPrize in Medicine went to Mary Brunkow, Fred Ramsdell & Shimon Sakaguchi for discovering regulatory T cells 🔬This important milestone has enabled centres like ours to advance research on the immune system 📎 elpais.com/ciencia/2025... #Research #Immunity #CNAG

🌍Can you imagine having the genome of every species on Earth? That’s the goal of @ebpgenome.bsky.social: sequencing 1.8 million eukaryotic species by 2035 CNAG's joined the challenge! Discover the full story in this report by Glenn Zorpette for @spectrum.ieee.org spectrum.ieee.org/whole-genome...

🙌 Really excited to participate in the 6th Annual 3TR Meeting! CNAG is helping build the project’s backbone: a centralised database integrating seven autoimmune, allergic, and inflammatory conditions to provide insights into treatment responses and non-responses @ivoleist.bsky.social #3TR #CNAG

💜 Latest update from #Unicas_Hackathon: 3️⃣ diagnoses already achieved! 💪In the months ahead, we hope to find answers for the remaining families, with the collaboration of this team of over 100 experts and the genomic data sequenced and analysed by CNAG #RareDiseases @sjdhospitalbarcelona.org

🚀BioSpain kicks off today in Barcelona! 🧬Visit us at one of Europe’s leading biotech events 👉We are OmicsTech, the ICTS Infrastructure of Omics Technologies, formed by CNAG, @crg.eu & COS @eurecat.bsky.social Ready to take your research to the next level? See you there! #BIOSPAIN2025 #ICTSNews

🙌¡Maratón por las enfermedades raras! 💜Ayer empezaba el primer Únicas Hackathon, un encuentro de clínicos, investigadores y genetistas para hallar el diagnóstico de 12 casos pediátricos en 48 horas 🧬Como colaboradores, nuestro equipo fue hasta Murcia para ayudar a la causa @sjdhospitalbarcelona.org

🇸🇪 Tomorrow we’ll be at the @ga4gh.org 13th Plenary in Sweden! 🗣️ Our Head of Bioinformatics, Sergi Beltran, will join the panel “GA4GH supporting genomics in clinical practice at the national level” (12–13h) 📺 Watch it live online: www.youtube.com/GA4GH #ga4gh13thplenary #CNAG @inserm.fr #Genomics

✨Yesterday we held the Advanced Course on Long-Read Sequencing & Medical Genomics! 👥 Over 200 joined online, and nearly 100 attended in person at KU Leuven 🗣️ Pedro M. Rodríguez Cruz, our Clinical Genomics Specialist, shared insights into African neuromuscular disorders @easigen-eu.bsky.social

🔝New advances in cancer: an epigenetic algorithm unlocks its past and future Published in @nature.com by @idibaps.bsky.social & @icr.ac.uk with CNAG's contribution, the study found that DNA methylation can be a molecular signature, tracing tumour origins and evolution 🔗 www.cnag.eu/news/epigene...

📢New event: 2nd International Conference on Clinical Research Networks for Rare Diseases! Organised by @erdera.bsky.social, an EU-funded project with CNAG as a partner 📅9–10 December 2025 📍Heidelberg & Online 🔗Programme and registry: loom.ly/1fhf8zI #RareDiseases #CRN2025 #ClinicalResearch #CNAG

🚨 Tomorrow is the day! Get ready for an exciting day as we kick off the 𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐜𝐨𝐮𝐫𝐬𝐞 𝐨𝐧 𝐥𝐨𝐧𝐠-𝐫𝐞𝐚𝐝 𝐬𝐞𝐪𝐮𝐞𝐧𝐜𝐢𝐧𝐠 𝐚𝐧𝐝 𝐦𝐞𝐝𝐢𝐜𝐚𝐥 𝐠𝐞𝐧𝐨𝐦𝐢𝐜𝐬🧬 📍 On-site attendance: 8:30 - 18:00 (CET) 💻 Online attendance: 8:50 – 18:00 (CET) Thank you to all participants, we look forward to welcoming you! ✨

🙌New targeted therapy for cholangiocarcinoma! The study shows that dual inhibition of NOX1 & NOX4 can slow progression in this high-risk cancer 🧬 CNAG performed RNA-seq (@annaesteveco.bsky.social) in this work, led by @ciccancer.bsky.social & @idibell.bsky.social 🔗 www.nature.com/articles/s41...

🚀New advances in Chronic Fatigue Syndrome & Long Covid-19! Led by @ibecbarcelona.eu, with our contribution (@annaesteveco.bsky.social), the study shows that skeletal muscle progresses through a hypermetabolic state, leading to muscle & mitochondrial deterioration iopscience.iop.org/article/10.1...