Nice summary on our paper on mechanisms controlling development and evolution of the cone-dominant ground squirrel retina, which is now in final form at eLife. www.lifescienceeditors.com/2026/01/06/h...

New collaborative preprint! A striking result: a disordered linker in KANK1 binds as many as 15 LC8 dimers, forming a protein rod that bridges cell membranes and microtubules! www.biorxiv.org/content/10.1...

Bio-Architecture O.O

Thrilled to share the preprint from my PhD! 🥳 Where I characterised epithelial cell extrusion in a sea anemone 🔗 www.biorxiv.org/content/10.6... Big thanks to my supervisor @prhsteinmetz.bsky.social and coauthors @noahbruderer.bsky.social @lionlchristiaen.bsky.social at🇳🇴 @msarscentre.bsky.social ⬇️🧵

Tour de force #UExM study of #protist #cytoskeleton structures (>200 species🤯), led by @dudinlab.bsky.social, @gautamdey.bsky.social. A must for #tubulin & #centrin aficionados🤩 www.cell.com/cell/fulltex...

🧵 Cytoskeleton question of the day: You want to localize your favourite protein. What do you trust first? 🔹 GFP overexpression 🔹 CRISPR knock-in 🔹 Commercial Antibodies 🔹Homemade antibodies 🔹 Or “all of the above + controls” 👀

Christmas party of the centriole lab - December 2075

Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles! www.biorxiv.org/content/10.6...

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1... Soon at @spirochrome.com Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

'Cum hoc ergo propter hoc' Correlation does not imply causation. Here a 'sequence' of 3 nuclei that of U2OS cells #FluorescenceFriday #Microscopy #Expansion

Thrilled to share that my postdoc paper has just been a published in @plosbiology.org ! Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work. Proud of what we achieved together! journals.plos.org/plosbiology/...

After years of struggling with how to cryopreserve one of our endosymbiotic bacteria, we found something that worked! 🦠☃️ We crowd-sourced suggestions and then @ruthwright.bsky.social tried the most common ones (like 🥛...). Want to do the same? Here is how we did it: www.biorxiv.org/content/10.6...

Heading to #CellBio2025 @ascbiology.bsky.social @embo.org? Stop by my poster P0101 tomorrow (Sun, 12:45 PM) in the session “Cytoskeleton and Motility-Microtubule Organization and Dynamics”. Looking forward to lively discussions on tubulin regulation & microtubule organization. See you in Philly!

Interested in applying U-ExM to cells, tissues, organoids, or cryo-sections? Our EMBO workshop is open for applications! 🧫🔬 Deadline: 12 Jan 2026 — don’t miss it!

New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen

Just uploaded our new preprint to @ecoevorxiv.bsky.social Multinucleate life really is everywhere...from deep sea forams to slime molds, intracellular parasites, and beyond. 🚀 We explore how scaling, ecology, & evolution intersect when many nuclei share a single cytoplasm. doi.org/10.32942/X2M...

Grants writing tips: (1) Rejections are totally normal, have faith in your idea, push it and improve it; (2) Every panel is different. Study it and prepare your grant for them; (3) Grant-writing takes months. Plan it and get diverse feedback and (4) Have fun with it! The work there is never wasted 😜

In 2023, we first sampled from a geothermal tributary at LVNP and using enrichment culturing, found an amoeba growing at high temp.

The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj

An interesting essay by Oliver Hobert on 'Paraneurons': "unifying sensory receptors located on external or internal epithelial cells feeding into the nervous system, as well as effector cells of the nervous system that respond to neuronal stimuli by […] [Original post on biologists.social]

‪ Congratulations @centriolelab.bsky.social @dudinlab.bsky.social and @gautamdey.bsky.social for your publication in @cp-cell.bsky.social: Charting the landscape of #cytoskeletal diversity in #microbial eukaryotes #Expansion #Microscopy @sciencesunige.bsky.social www.unige.ch/medias/en/20...

Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead! www.science.org/doi/10.1126/...

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction! Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1 doi.org/10.1101/2025...

Me describing my grant idea to my fellas: A masterpiece of logic and innovation VS Me actually writing it at 2 AM: Chaos and disillusion

Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @cellcellpress.bsky.social www.cell.com/cell/fulltex.... What’s new?

Launching celldynamicslab.com, the homepage of our new group at EPFL working on cell fragmentation, membrane and cortex mechanics, FLIM imaging, and microfluidics tools. MSc/PhD or postdocs interested in quantitative cell biology are welcome to reach out. We're also hiring a lab manager in 2026!

Check this one out! Outstanding review to understand all the different approaches that are being used to understand the structure and function of the Cilia and the centriole :) #cytoskeleton #cellbiology PS: and congrats for the cover🥰

Just posted, "The Tiling Tree Method, Part 2: Common Pitfalls and How to Overcome Them" a follow-up to our previous essay on the "tiling tree" method for thinking of all the possible solutions to a problem, by Claire Wang, Nina Khera, and myself. engineeringx.substack.com/p/the-tiling...

This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs. I believe last one is a 🕷️ #FluorescenceFriday #Microscopy

📻 Interview de Virginie Hamel du @centriolelab.bsky.social pour CQFD de la #RTS: Une méthode ouvre lʹaccès à lʹarchitecture interne du #plancton #microscopie #expansion www.rts.ch/audio-podcas... @mocel.bsky.social @sciencesunige.bsky.social @dudinlab.bsky.social

🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬 This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share! www.findaphd.com/phds/project... 🧪

The A–C linker structure!!! 🤩 Beautiful work. Even if you’re not as centriole-obsessed as we are, you’ll appreciate the elegance and complexity. Amazing to see U-ExM proteins in human centrioles fitting right into these densities. Congrats to all!

Immagine you could image two cellular structures in the same fluorescent channel and still reliably get them separated afterwards… What would you do with this? Now… what would you do if that also worked with 4 structures at once? 👇 #MicroSplit #preview🧵

🚨 We’re hiring a postdoc! 🚨 Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab! Reach out directly: [email protected] Learn more: bonetponcelab.com Let’s chat!

I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.

Stoked to share TWO preprints on mitochondrial pearling! 🎉 We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and @gavsturm.bsky.social et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪


1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.

Heading to HD! Despite my sleepy face I can promise that Im very excited to join the Seeing is Believing 2025 @events.embl.org If you are interested in centrosomes, centrioles, expansion microscopy or protist, don't be shy and let's have a chat! ☺️🤗 #EMBLSymposium #microscopy

UNIGE postdoc? 🎓 Interested in sharing your research in a friendly seminar? Join the new SCIENCE CLUB with Physics, Chemistry & Biology colleagues! Contact us for details 👍 Not a postdoc? Please share with yours!

Really nice contribution of @arcadiascience.com of open high quality drawings across the tree of life. Take a look! research.arcadiascience.com/pub/resource... 😍😍

Now out on bioRxiv. 🥳My research on #cytokinesis, averaging thousands of #ExM images🔬, creating a dynamic atlas of cytokinesis 🦠⏳. Here's an animated sneak peek of what we found. Better resolution on bioRxiv😄 #PSFoftheGIF

#GEF25 the expansion microscopy community would benefit from high NA, long working distance water objectives. Who's working on these? What's out there?

Be our new colleague! 🎉 The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor. 👉 More details here: lnkd.in/e8Z9eAm4 👉 Our department: mocel.unige.ch Please feel free to share this opportunity with your network.

Finally 🥂

Our latest preprint on the role of the Arp2/3 complex in mitotic entry is now available @biorxiv. This work was done by Dhanya Kalathil, a very talented postdoc in my lab. The story started in 2019 when we were investigating the role of branched actin in cytokinesis. 1/

Lately I've been only posting images of really interesting protist here, but something that many don't know is that most of my time i'm expanding 'boring' mammalian cells and that I love human centrioles. Don't tell me that they are not beautiful😍👁️ #FluorescenceFriday #CellBiology #Cytoskeleton

It’s truly inspiring to see how persistence, collaboration, and communication across disciplines can transform ambitious ideas into such impactful stories. Seven years, four interdisciplinary teams, and countless discussions later—this really shows the power of timing, teamwork, and shared vision!😍

Call for papers: Cell Biology of the Nucleus We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by @abbybuch.bsky.social alongside JCS Editor Megan King @luskinglab.bsky.social. Deadline: 3 November journals.biologists.com/jcs/pages/nu...

Wanna see acting in Expansion? Check this one out then😍👇