Want to measure protein-protein interactions? We recently did some dreaming about how you can do this with a single fluorescent tag using molecular "tumbling." We simulated how you'd do this on a lightsheet, a flow cytometer, or a cheap handheld device. We even took prelim data on a commercial rig:

I no longer have the follower count nor the algorithm to help promote stuff, but @jlazzaridean.bsky.social and Andy York reached out to me a while ago to do an animation explaining a way to measure moluecular "tumbling" and I think it worked out pretty well! andrewgyork.github.io/tumbling_is_...

Hi bluesky! Excited to share some new work in voltage sensing I was a part of in my past life in the Evan Miller lab at Berkeley: a versatile dye for both fast voltage imaging and lifetime-based quantification Introducing CRhOMe: www.biorxiv.org/content/10.1...