André Schneider, University of Bern
@schneian.bsky.social
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📥 165
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Biochemist interested in mitochondria, trypanosomes and science in general
pinned post!
A piece of science history about RNA, oxygen, and mice cages There is nothing is more important in an experiment than the proper controls. But what should you do if your experimental control fails? - read my short essay on failed experimental controls.
www.embopress.org/doi/full/10....
?
about 1 year ago
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André Schneider, University of Bern
John Bistline
2 days ago
This is my favorite climate change chart. Japanese monks, aristocrats, and emperors kept meticulous records of cherry blossom festivals for 1,200 years and accidentally built the world's longest climate dataset.
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André Schneider, University of Bern
Ian Sudbery
4 days ago
This is of course hard on the junior and untenured, but not as hard as some seem to think. Is it better for your metees to burn through 5 postdocs so that one lucky one gets a CNS paper, or is it better for all 5 to get respectable, but less glam publications?
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André Schneider, University of Bern
Ian Sudbery
4 days ago
Deciding not to submit to CNS is, in part, deciding to be happier doing good science and having a "sucessful" career, as measured by traditional measures. Will chasing glam journals hurt my chances of making full Prof? Who knows? Do I care that much about making full Prof? Not really.
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André Schneider, University of Bern
Faria Tryps Lab
5 days ago
(1/7) How does T. brucei achieve a 140-fold stoichiometric excess of VSG mRNA over upstream ESAGs from a single polycistronic unit? Our latest research in
@natmicrobiol.nature.com
reveals a mechanism of spatially regulated RNA decay to fine-tune expression of virulence genes
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André Schneider, University of Bern
Jonathan Eisen
11 days ago
Nice article about cave microbes and the work of people like Hazel Barton from BBC News
www.bbc.com/future/artic...
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'Predators that just run in and grab, stab and kill': The deep cave bacteria resistant to modern medicine
In the brutal world of deep caves, bacteria live in a miniature world of terror. The weapons they have evolved can defeat antibiotics – but now they are inspiring powerful new drugs.
https://www.bbc.com/future/article/20260318-the-deep-cave-bacteria-resistant-to-modern-medicine
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André Schneider, University of Bern
Writing our Destiny aka Andrew
14 days ago
OMG, the passenger riding along!
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André Schneider, University of Bern
OMühlemann lab
23 days ago
Congratulations Sebastian!
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André Schneider, University of Bern
Marie Ruiz-Vidal
about 1 month ago
Hergé
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André Schneider, University of Bern
Sebastian Shaw
about 1 month ago
🚨 Postdoc position 🚨 I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026). Details & application:
jobs.uzh.ch/job-vacancie...
. Please share! 😊
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UZH: Postdoc
The newly founded Cryptosporidium lab at the Institute of Parasitology focuses on the genetic and transcriptomic basis of parasite virulence and persistence in Cryptosporidium and is committed to incl...
https://jobs.uzh.ch/job-vacancies/postdoc/e639e72a-6302-42f7-9a1e-cbcb2f2c4a57
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How many mechanistically different protein insertases are there? Maybe fewer than you think! Check out our tale of pATOM36, MIM, MTCH1/2 and YidC in the preprint by Stephan Berger of the Schneider and the Ballmoos Labs.
www.biorxiv.org/cgi/content/...
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https://www.biorxiv.org/cgi/content/short/2026.02.13.705746v1
about 2 months ago
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André Schneider, University of Bern
Sophien Kamoun
about 2 months ago
Vorholt Lab re-created endosymbiosis in the lab: injected bacteria into a fungus and evolved a heritable partnership. Evolution, fast-forwarded.
doi.org/10.1038/s415...
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Inducing novel endosymbioses by implanting bacteria in fungi - Nature
A study presents an approach to establish and track a new endosymbiotic partnership by implanting bacteria in a non-host fungus and shows that stable inheritance of the implanted bacteria is possible ...
https://doi.org/10.1038/s41586-024-08010-x
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André Schneider, University of Bern
Yasin Dagdas
about 2 months ago
This is a beautiful case of how real science happens & serious scientists work. Kudos to both set of authors: “This has been a humbling experience, but one that speaks to the self-correcting nature of the scientific endeavor.”
www.science.org/doi/10.1126/...
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RETRACTED: Integrative phylogenomics positions sponges at the root of the animal tree
Determining whether sponges or ctenophores root the animal tree has important implications for understanding early animal evolution. Here, we examined support for these competing hypotheses by constru...
https://www.science.org/doi/10.1126/science.adw9456#elettersSection
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André Schneider, University of Bern
about 2 months ago
With new book 'The Dawn Fisherman' out soon, delighted to have explained with co-author Ralf Dahm to
@meganwollerton.bsky.social
at National Geographic how pus, old bandages (& later, salmon gonads!) led to discovery of DNA in freezing cold castle kitchen!
www.nationalgeographic.com/history/arti...
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The discovery of DNA started with this overlooked scientist
In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would later reshape biology and our understanding of life itself.
https://www.nationalgeographic.com/history/article/friedrich-miescher-nucleic-acid-nuclein-dna-helix
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André Schneider, University of Bern
Dewar Lab
2 months ago
🧬Fully Funded PhD Mitochondria|Protein Homeostasis|Antibody Technologies 🤝In collaboration with
@menzieslab.bsky.social
and Nick Robinson
@blslancasteruni.bsky.social
🎓UK students only ⏰6th March 2026 📩Enquiries:
[email protected]
www.findaphd.com/phds/project...
#phdopportunity
#mitochondria
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Safeguarding the powerhouse: antibody-based characterisation of trypanosome mitochondrial quality control proteins at Lancaster University on FindAPhD.com
PhD Project - Safeguarding the powerhouse: antibody-based characterisation of trypanosome mitochondrial quality control proteins at Lancaster University, listed on FindAPhD.com
https://www.findaphd.com/phds/project/safeguarding-the-powerhouse-antibody-based-characterisation-of-trypanosome-mitochondrial-quality-control-proteins/?p193962
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I find this kind of ironic, this is what happens if AI generated content is not checked.
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2 months ago
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This could be big! - Got it in January
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2 months ago
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André Schneider, University of Bern
Christophe 🔬 L
3 months ago
Tracking the details of an experiment in successively cited Methods sections
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André Schneider, University of Bern
John Shirley
3 months ago
Nature can be wickedly cunning.
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Tropical spiders craft giant doppelgängers as decoys
The extraordinary anti-predator strategy of two tiny, orb-weaving spider species has been uncovered by scientists from The Australian National University (ANU) and the University of Florida.
https://phys.org/news/2025-11-tropical-spiders-craft-giant-doppelgngers.html
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André Schneider, University of Bern
3 months ago
💊 Resistance against antibiotics is a severe threat - also in 🇨🇭 The Forum Phagentherapie discusses with experts and the public about solutions. 👉 Register for our phage forum on Jan 31 in Basel:
lnkd.in/e-im3e-g
‼️ Voices from society and patients are vital to develop viable approaches.
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André Schneider, University of Bern
Dr. Raphael Marschall
3 months ago
The winner of ✨
#planetaryScience
image of 2025 ✨ is ✨Uranus as seen by JWST✨ Taken on: October 6, 2025 Credit: NASA/
@esa.int
/CSA/
@stsci.edu
/
@andrealuck.bsky.social
Full resolution:
www.flickr.com/photos/19227...
🧪⚛️
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David got company!
4 months ago
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André Schneider, University of Bern
Mark Histed
4 months ago
Well, this is an utter disaster for science. This gutting of peer review is very likely driven by Project 2025/OMB/Vought, very likely is about funding junk science, and very likely is coming for
#NIH
and biomedical research next. 🧪
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André Schneider, University of Bern
Carl T. Bergstrom
4 months ago
This is actually the trippiest thing I've ever seen that was not deliberately created by M C Fucking Escher. It straight up took me over a minute to make sense of and now I can't go back. This is the white-and-gold dress on a gram a week of trenbolone.
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In the early 1980ies the labs of Cordingley, Boothroyd and Borst discovered that the LSU rRNA of T. brucei is processed into 6 fragment. Now more than 30 years later Simona Amodeo at al. found the factors that mediate these trypanosomatid-specific processing events.
academic.oup.com/nar/article/...
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A trypanosome-specific complex mediates late-stage processing of cytosolic LSU rRNA
Abstract. Unlike most eukaryotes, Trypanosoma brucei processes its cytosolic large subunit (LSU) RNA into six fragments. The factors responsible for these
https://academic.oup.com/nar/article/53/22/gkaf1327/8378191
4 months ago
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André Schneider, University of Bern
Andrew Straw
4 months ago
Have you ever wondered what you would find if you could keep your eyes on a bee for more than a few meters? Us, too! preprint (with videos!) + thread 🧵 Precise, individualized foraging flights in honey
#bees
🐝 revealed by multicopter drone-based tracking
www.biorxiv.org/content/10.6...
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Alex Klotz
4 months ago
I wanted to take the bus but it was stationary
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André Schneider, University of Bern
Itai Yanai
4 months ago
How does a caterpillar completely dissolve inside its chrysalis, before reconstructing itself in the shape of a butterfly? “Metamorphosis is wild,” marvels historian Oren Harman in his beautiful new book, which I reviewed for this week's
@nature.com
www.nature.com/articles/d41...
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André Schneider, University of Bern
Eva Nowack
4 months ago
📢Postdoc position available!🧪🧫🧬 Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions. Full details & application:
karriere.hhu.de//index.php?a...
. Please help us get the word out!
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Postdoc (m/f/d) in Endosymbiosis Research
https://karriere.hhu.de//index.php?ac=jobad&id=535
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André Schneider, University of Bern
Paolo Crosetto
5 months ago
What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma. It's *scientific publishing*. We call this the Drain of Scientific Publishing. Paper:
arxiv.org/abs/2511.04820
Background:
doi.org/10.1162/qss_...
Thread
@markhanson.fediscience.org.ap.brid.gy
👇
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André Schneider, University of Bern
Barba Papa 🏳️🌈 The Bear Did Lady
5 months ago
Schrödinger: Excuse me, miss, can I borrow that box for a science experiment? Pandora: Sure, be my guest.
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André Schneider, University of Bern
- Picture by Raymond Gosling and Rosalind Franklin, King's College - DNA by Rudolf Signer, University of Bern
add a skeleton here at some point
about 1 year ago
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André Schneider, University of Bern
Dacks Lab (Evolutionary Cell Biology)
5 months ago
Holy smokes!!!!
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André Schneider, University of Bern
Philippe Bastin's Lab
over 1 year ago
Here we are! To celebrate our arrival, here is a
#trypanosome
expanded ~13 times & stained for tubulin, individual cortical
#microtubules
can be recognised, what was only achievable by EM before. Images: Christine Girard-Blanc & Thierry Blisnick. Many thanks to
@centriolelab.bsky.social
for training
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André Schneider, University of Bern
NCCR RNA & Disease
5 months ago
Paper by the Schneider lab(
@schneian.bsky.social
) & collaborators w/co-first authors Corinne von Känel & Salome Aeschlimann "TbTim20 facilitates protein import at a low membrane potential in trypanosomes lacking the mitochondrial genome"
@febsj.bsky.social
nccr-rna-and-disease.ch/news/article...
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Multiple so called "quality control checks" by the journal almost killed us. - But now it is out! A novel mito. protein import factor is only essential in T. brucei without kDNA. – Check it out. Congrats, to the first authors Corinne and Salome and to all our coauthors.
doi.org/10.1111/febs...
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FEBS Press
Protein import into mitochondria relies on TIM complexes and the membrane potential. Trypanosoma brucei has a unique TIM complex, and the role of one subunit, TbTim20, has remained unclear. Here, we ...
http://doi.org/10.1111/febs.70297
5 months ago
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André Schneider, University of Bern
PLOS Biology
6 months ago
The flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in
#Trypanosome
.
@mbonhivers.bsky.social
&co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures
@plosbiology.org
🧪
plos.io/4n3bWi6
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André Schneider, University of Bern
Jeffrey J. Hall
7 months ago
Video: a Japanese scientist was attacked by flies while giving the acceptance speech for his Ig Nobel Prize-winning research paper that proved painting Zebra-like stripes on cows led to a decrease in biting fly attacks.
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...and now something for RNA enthusiasts @nccr-rna-disease.bsky.social The function of the vault complex has finally been solved: it is a lampshade.
6 months ago
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Another case of convergent evolution?
7 months ago
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Convergent Evolution? – Spiral staircase in the “Église Saint-Catherine” in Loix, France
7 months ago
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André Schneider, University of Bern
Bungo Akiyoshi
7 months ago
Congrats to all authors, especially Lim who had an impressive PhD viva last week! TAC is a very interesting structure linking mitochondrial DNA and basal bodies in trypanosomes
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The trypanosomal TAC of is required for mitochondrial DNA segregation: Discovery of the novel TAC53 subunit and the tubular arrangement of the TAC filaments Joint study by the Ochsenreiter and Schneiderlabs. 👏 to 1. Author Lim.
journals.plos.org/plospathogen...
#mitochondria
#mtDNA
#Trypanosoma
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Connecting basal body and mitochondrial DNA: TAC53 and the tubular organization of the tripartite attachment complex
Author summary Trypanosoma brucei, is the causative agent of human African sleeping sickness and nagana in cattle. The eukaryotic parasite relies on the faithful inheritance of its singular mitochondr...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1013521
7 months ago
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André Schneider, University of Bern
Olivier Pertz
7 months ago
so happy to have Katie as a colleague !
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André Schneider, University of Bern
Florian Aigner
7 months ago
Sie haben friedliche Menschen gewaltsam attackiert! Was haben Sie zu Ihrer Verteidigung zu sagen? Ach? Sie dachten, das seien Klimaschützer? Ach so! Na dann ist es gut. Das kann schon mal passieren.
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The trypanosomal TAC is required for mitochondrial DNA segregation. We provide insight into TAC assembly: one of the most extreme sorting event for any mitochondrion. Congratulations to Philip, Salome and Bernd
#mitochondria
#mtDNA
#Trypanosoma
journals.plos.org/plospathogen...
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Assembly of the mitochondrial outer membrane module of the trypanosomal tripartite attachment complex
Author summary Mitochondria are essential for nearly all eukaryotes. This requires proper segregation of the organelles and their genomes to the daughter cells during cell division. For Trypanosomes a...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1013506&?utm_id=plos111&utm_source=internal&utm_medium=email&utm_campaign=author
7 months ago
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André Schneider, University of Bern
Jonathan Eisen
7 months ago
Anna's hummingbird in my yard moments ago.
#DavisCA
,
#birds
,
#wildlife
#birdphotography
#hummingbirds
#NikonD500
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André Schneider, University of Bern
Reymond Group
7 months ago
🎊The Front Cover Art for our recent paper: A View on Molecular Complexity from the GDB Chemical Space
@yebuehler.bsky.social
and Jean-Louis Reymond is now out @JCIM! 👉
tinyurl.com/yc4ufsfw
@acs.org
@pubs.acs.org
@unibe.ch
@DCBPunibern
#MyACSCover
#chemicalspace
#drugdiscovery
#molecules
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André Schneider, University of Bern
Madonna Lennon
7 months ago
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André Schneider, University of Bern
Florian Aigner
7 months ago
Dem Menschen, der dafür verantwortlich ist, dass Microsoft Word "DNA" automatisch auf "DANN" ausbessert, wünsche ich von Herzen, dass alle seine fallengelassenen Marmeladebrote mit der bestrichenen Seite nach unten auf dem Boden aufkommen.
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Alexander Harms
8 months ago
Dialog with society about phage therapy - our Agora project is taking off! Getting ready for lots of events across the country (D/FR):
phagenforum.ch
💊🎙️🇨🇭
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