Sam Mugford
@samtmugford.bsky.social
📤 998
📥 2036
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Science worrier, decoding bugs
https://orcid.org/0000-0002-8537-5578
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Sam Mugford
derek guy
1 day ago
RIP Mark Rothko. You would have loved how the hydrogen peroxide bleach is only turning the Reflecting Pool blue around the perimeter
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Louie Stowell
3 days ago
Also: I like that they're not bothering to ban bluesky cos they know everyone here is (apologies to whoever said this for not attributing it) 46.
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End Deportations Belfast
5 days ago
Absolutely huge crowds in Belfast to reject the far-right, paramilitarism, racism and border violence. A loud message to the politicians who pandered to violent paramilitary groups this week
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Parami
5 days ago
Thats my city thank you Glasgow
www.thenational.scot/news/2619197...
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Thousands of anti-racism protesters drown out far-right rally in Glasgow
Thousands of anti-racism protesters gathered in Glasgow on Saturday in response to violent anti-immigration disorder that broke out in the city on…
https://www.thenational.scot/news/26191974.thousands-anti-racism-protesters-gather-glasgow/?ref=li
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Thomas Ott
6 days ago
Happy to share our newest preprint. We developed guidelines and analysis workflows for FLIM Imaging in plants. Multiplexing with spectrally overlapping fluorophores in plants is now possible. Have a look. Any feedback is more than welcome.
www.biorxiv.org/content/10.6...
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Phil Sturgeon 🌳🚵⚓️
7 days ago
Yes yes it’s early days but people used to say solar desalination wasn’t possible, and now it’s out there working fine all over the world. Then they said they’d never be able to deal with the brine and oh look there getting there. Keep doing the impossible. We’re gonna need it.
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Matt Baume 🏳️🌈
7 days ago
Happy Pride to this Caravaggio self-portrait that made one man so gay he had to go to the hospital
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Rodrigo Reis
7 days ago
Cool new T-DNA plasmid! Let's see how it gets adopted and common tools become available -- hope those will happen to some level at least
www.biorxiv.org/content/10.6...
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Rational design of T-DNA vectors enables predictable, single-copy integration in Arabidopsis thaliana
Agrobacterium-mediated transformation is the dominant method for plant transgenesis, yet it frequently produces multi-copy, structurally complex T-DNA insertions associated with transgene silencing, u...
https://www.biorxiv.org/content/10.64898/2026.06.08.730999v1?rss=1
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Mauricio Contreras
13 days ago
Molecular mimicry of a pathogen virulence target by a plant immune receptor | Science
www.science.org/doi/10.1126/...
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Molecular mimicry of a pathogen virulence target by a plant immune receptor
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
https://www.science.org/doi/10.1126/science.aef9946
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Hayden Wright👻
13 days ago
Perhaps Farage hasn't said anything because he is respecting the family's wishes?
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Oded Rechavi
13 days ago
I won't pay $4,000 for a ticket to see my Knicks play in the NBA Finals for the first time in 27 years, but for some reason I routinely pay three times that much for open access to papers that I wrote myself.
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Mat Johnson
14 days ago
Congratulations to everyone who said it would get this bad. Your prize is watching everyone who disagreed now claim no one could have predicted it would get this bad.
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Mike Boylan-Kolchin
15 days ago
"AI is operating at a PhD level" oh, so it's replying 'sorry for the late response' to every email and complaining about its labor conditions?
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Katherine Brown
15 days ago
Over the past year,
@biologyopen.bsky.social
has expanded its Fast & Fair initiative to accelerate peer review. The results are impressive - take a look at their latest preprint to find out more:
www.biorxiv.org/content/10.6...
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Dr. Lucky Tran
16 days ago
BREAKING: Mayor Mamdani just signed an “executive order” to repeal bedtime so NYC kids can watch the Knicks play in the NBA Finals!
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mara lawniczak
20 days ago
If you are interested in collecting specimens for chromosomal genomes and/or generating chromosomal reference genomes from specimens that were not cold-chain preserved, please read on and share this thread.
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Caitlin G. DeAngelis
about 1 month ago
Recently, FamilySearch digitized and uploaded tons of microfilmed records, including many from 18th-century Massachsuetts. They're using some sort of AI to transcribe/summarize the handwritten documents. I've noticed that the AI strips out references to race and enslavement in 18thc documents.
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British Society of Plant Pathology
about 1 month ago
Early bird registration for PPATH2026 closes 31 May. Save money and secure your spot at the BSPP's annual conference. 8–11 September 2026, Norwich. Student members get a reduced rate, worth joining if you haven't already. Register:
tinyurl.com/EPCC2026
#PlantPathology
#PlantHealth
#PlantScience
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This is the rebel alliance we need
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about 1 month ago
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Prof. Ian Walker
about 1 month ago
We don't view motor violence like all the other violence, Exhibit 746
www.theguardian.com/lifeandstyle...
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‘We’re not out to get anyone – we just want to slow you down’: why do lollipop people face so much road rage?
They just want to help children safely across the road on their way to and from school. Yet lollipop people are having to wear body cameras after an increase in abusive and dangerous drivers. How did ...
https://www.theguardian.com/lifeandstyle/2026/may/13/why-do-lollipop-people-face-so-much-road-rage?CMP=Share_AndroidApp_Other
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Adam Steinbrenner
about 1 month ago
We hope BAT will help molecular biologists to think in terms of gene trees. Evolutionary signal within gene families is often the first clue that there is amazing, novel biology to be found. Check out our repo and try out BAT analyses of YFGs (Your Favorite Genes!)
github.com/steinbrenner...
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GitHub - steinbrennerlab/blast-align-tree: A pipeline to identify BLAST hits and perform phylogenetic analysis across multiple queries and local genome databases
A pipeline to identify BLAST hits and perform phylogenetic analysis across multiple queries and local genome databases - steinbrennerlab/blast-align-tree
https://github.com/steinbrennerlab/blast-align-tree
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Sam Mugford
sweetie π
about 1 month ago
always listen to tina
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Some biologists took the realisation that the universe is a simulation to replace the phrase ‘shows signs of diversifying selection’ - when anaylsing DNA sequence data- and instead saying ‘the creator shows signs of an inordinate fondness for this region of the genome’
about 1 month ago
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Grumpy-ish Brian🏴🇪🇺🇮🇪
about 1 month ago
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jamelle
about 1 month ago
the most anti free speech administration in this country’s history
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Larry Clapp
about 1 month ago
Douglas Adams has entered the chat. (Yes, from the afterlife.)
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Dr. Merritt Rae Turetsky
about 1 month ago
Last fall, this deep sinkhole appeared at one of our field sites, with ground collapse happening in just a few weeks. This is what abrupt permafrost thaw looks like, with implications for soil stability, erosion, and methane emissions. Will be curious to see what happens here this summer.
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Tom Flood
about 1 month ago
so sorry.
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Sam Mugford
about 2 months ago
A date to mark in your calendars if you are interested in co-evolution, plant health or population genetics! 🐛🌳🦠🌿🍄🟫 Register for a short presentation, en Français or in English, or to get in touch if you would like to attend. Submit details for a presentation:
framaforms.org/inscription-...
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Sam Mugford
Michael Hobbes
6 months ago
If we are banning cell phones for kids we need to be talking about banning chatbots for boomers
www.persuasion.community/p/my-chatgpt...
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Paul Boldrin
about 2 months ago
I read a history of early 20th century socialism and it's crazy how much of it is just clubs doing art or reading books and trying to get miners and factory workers to do art and read books.
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Fantin Mesny
10 months ago
📣 NEW PREPRINT 📝 We identified evolutionary origins of many fungal effectors! We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...
cc
@teamthomma.bsky.social
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Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...
https://www.biorxiv.org/content/10.1101/2024.01.04.574150v2
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Elisabeth Bik
about 2 months ago
J. Craig Venter, Scientist Who Decoded the Human Genome, Dies at 79 A risk-taking outsider, he brought speed, competition and controversy to one of science’s biggest races.
#GiftLink
Nicholas Wade writes
@NYtimes.com
www.nytimes.com/2026/04/30/s...
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J. Craig Venter, Scientist Who Decoded the Human Genome, Dies at 79
https://www.nytimes.com/2026/04/30/science/j-craig-venter-dead.html?unlocked_article_code=1.e1A.E3Rx.vq7Ej-lma3R2&smid=nytcore-ios-share
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Sam Mugford
Şuayb Üstün
about 2 months ago
🚨 Paper out now in
#ScienceAdvances
@science.org
🌱🦠 Pathogens don’t just target protein degradation—they also hijack host translation. "Bacteria use P-body condensates to attenuate host translation during infection" ⚖️♻️ led by
@manuelgonzalezfuen.bsky.social
www.science.org/doi/10.1126/...
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Sam Mugford
British Society of Plant Pathology
about 2 months ago
Are you an early-career plant pathologist? Early Careers Plant Pathology (ECPP2026) is the conference for you. A full day of talks, posters and networking, just for students and early career researchers. 8 September 2026, John Innes Conference Centre, Norwich. Register now:
tinyurl.com/EPCC2026
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Fiona Tribe
about 2 months ago
Yes, Swiss scientist Fritz Zwicky coined the term “dark matter” which is impressive, but he also coined the term “spherical bastard” to describe people who are bastards no matter which way you look at them, and I think that should be celebrated more.
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Very disappointing to hear
@markmiodownik.bsky.social
on Toxic on Radio4 tonight. Lots of scaremonging about possible risks, lots of correlation without mechanistic mechanism, very little evidence of real harm but lots of advice for people to change their lifestyle.
about 2 months ago
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Sam Mugford
Drew Schreiner
2 months ago
go home biology, you’re drunk. reverse transcriptase is now taking sequence instructions from a protein
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Sam Mugford
🦌 The Deer Whisperer 🦌
2 months ago
Good night, Bluesky! What's better than a Bald Eagle in the Moon?🦅🌕 How 'bout 2 of 'em?🦅🌕🦅 📸Josh Palmer
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Its strangely apropriate to name this after somone famous for having her data stolen and not being given credit
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2 months ago
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Sam Mugford
Derrick Kamp
2 months ago
I've been working to visualize the biogeography of the aphid's intracellular symbiont within whole insects. The pink bacteria live in the host's specialized bacteriocytes and embryos. Really excited about where this work is going!
#FluorescenceFriday
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Sam Mugford
The Sainsbury Laboratory
2 months ago
We are happy to celebrate
@mpcontreras.bsky.social
winning the
@biochemsoc.bsky.social
2027 Early Career Research Award! Mauricio joined TSL as a predoc with
@kamounlab.bsky.social
, where he did PhD and postdoc before starting his group at
@zmbp-tuebingen.bsky.social
Congrats Mau!
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TSL Alumnus wins Biochemical Society Award
Mauricio Contreras has been recognised as an exceptional Early Career Researcher by the Biochemical Society. Currently based at the University of Tübingen, Germany, Mauricio previously spent several…
https://www.tsl.ac.uk/news/tsl-alumnus-wins-biochemical-society-award
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Sam Mugford
Cephalopods Daily
2 months ago
In 2019, scientists velcro'd 3D glasses to European common cuttlefish (Sepia officinalis) They didn't do this just to make them look cool as fuck, but in order to study their vision. Using a 3D theatre made for the cuttlefish, they were able to test if cuttlefish have stereo vision (they do!)
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Sam Mugford
Ursula von der Leyen
2 months ago
Hungary has chosen Europe. Europe has always chosen Hungary. A country reclaims its European path. The Union grows stronger.
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Dannagal Goldthwaite Young
2 months ago
The Good News: From 1900 to 2023, almost half (46%) of countries that had gone from democracies to autocracies had REVERSED their democratic breakdown, with most of them ending or reversing the trend of autocratization within 5 years of its onset. (Nord & Lindberg, 2025).
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Sam Mugford
Alex McClelland
2 months ago
Great to see this paper in its final published form!
www.pnas.org/doi/10.1073/...
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Sam Mugford
Marc Somssich
about 2 years ago
#PlantScienceClassics
#13: Floral Dip. ~25 years ago, in 1998, Steven Clough & Andrew Bent published their ingeniously simple Arabidopsis transformation protocol in
#ThePlantJournal
: Dipping a plant upside down into Agrobacterium solution - et voilà!
doi.org/10.1046/j.13...
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Sam Mugford
Şuayb Üstün
2 months ago
Preprint alert 🚨 (1/10) 🧵 𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺: It can promote resistance, susceptibility, or restrict cell death 🤯 So what is its actual role? We show it acts as a spatial organizer of immunity across cell types 🌱🦠
#proteostasis
www.biorxiv.org/content/10.6...
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Casey Dreier
2 months ago
The FY 2027 NASA budget request hides its science cuts by omitting mission names instead of explicitly zeroing them out. We did the work and found 54 missions cancelled in this proposal. This is another extinction-level event for NASA science. Full list:
planetary.org/save-nasa-science
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