Structural basis for heat tolerance in plant NLR immune receptors. https://www.biorxiv.org/content/10.64898/2025.12.17.694812v1

Our lab (Evolution of Plant Signaling Lab) together with El Kasmi Lab and @mpcontreras.bsky.social Lab enjoyed a very Christmassy evening with Glühwein and many 🎄🎄🎄 not far from Tübingen. Cheers to a new year at the #ZMBP full of discoveries on immune receptors 🥂 #JuniorPIs #EMCRs #MPMI

The Clavel Group is recruiting a new postdoc for two possible projects dealing with plant-virus interactions and selective autophagy! More (wordy) details below ⬇️🌱🦠

New preprint by Judith Fliegmann and Lisha Zhang on an additional regulatory layer of #plantimmunity: the TIR-domain production of small molecules (typical during ETI) is required for PTI responses downstream of RLPs PRRs #MPMI #ZMBP

Small Molecule Binding to EDS1/PAD4 in LRR-RP-Mediated Pattern-Triggered Immunity https://www.biorxiv.org/content/10.64898/2025.12.10.692544v1

🔬 Call to create junior research groups at the Institut Pasteur Focus: Infectious diseases, host-microbe interactions, vaccines Special interest: AI methodologies 📅 Deadline: Feb 9, 2026 👥 2-12 years post-PhD Apply now 📝 research.pasteur.fr/en/call/crea... #JobOpportunity #Research

I’m happy to share our new preprint! We uncovered the full diversity of bacterial TIR-based antiviral immune signaling, massively expanded the known diversity of Thoeris systems, and revealed conservation of TIR-derived immune signals across the tree of life. www.biorxiv.org/content/10.6...

I just published: On the diversity of resting states of NLR immune receptors New story on rice Pik NLR immune receptor pair — turns out it sits as a 1 MDa membrane-bound beast before activation 🤯. Another wild twist in the ever-expanding universe of NLR resting states! medium.com/p/on-the-div...

Check out our new story on the famous rice Pik NLR pair, led by @clemmar.bsky.social and @hsuanpai.bsky.social! Turns out they form a massive 1 MDa membrane-associated complex before activation 🤯 A cool new example of the diversity of NLR resting states!

Excited to share our latest work on plant immune receptor biochemistry! @kamounlab.bsky.social @hsuanpai.bsky.social @mpcontreras.bsky.social Jose Salguero Linares @danielluedke.bsky.social @adnroide.bsky.social @jiorgoskourelis.bsky.social www.biorxiv.org/content/10.6...

The Pik NLR pair accumulates at the plasma membrane as a hetero-oligomeric sensor-helper immune protein complex prior to activation https://www.biorxiv.org/content/10.64898/2025.11.30.691369v1

Some news 🎉 After five incredible years in Tübingen, it’s time to say goodbye. Starting February, the Mutualisms Lab will relocate to the John Innes Centre, right next door to @berasymbionts.bsky.social and her group at The Sainsbury Laboratory 🪲🦠

We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes. Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...

Not all heroes wear capes! Thank you to @adelineharant.bsky.social for keeping the Kamounity running smoothly and supporting so many of us all these years! 🙏🙏🙏

I just published: Adeline Harant: Keeping an open mind is key for a fulfilling career in science A much-deserved tribute to the amazing Adeline Harant and her leadership at the bench and beyond. She also brings a dose of sanity to the @KamounLab madhouse. kamounlab.medium.com/adeline-hara...

📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project. This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes 📅 Closes on 10 Dec. www.jic.ac.uk/vacancies/36...

Hi everyone, a few years ago, we started a list of labs studying bacterial immunty for students, editors, conference organizers... (currently n=79). Update time ! Send me a message to 1) add your lab or others 2) Correct info docs.google.com/spreadsheets... #Phagesky #Microsky

My new Emmy Noether Group is recruiting! 🔬 Two PhD positions in plant pathogen evolution 🧬 Start: April 2026 (flexible) 📍 Dept. of Phytopathology & Plant Protection @rstam.bsky.social @uni-kiel.de ⏰ Apply by 15 Dec 2025 🔗 More info: www.uni-kiel.de/personal/de/... Do get in touch or share 😊

We wrote a review 📖 on hydathode immunity! Learn how bacteria exploit hydathodes to access the vasculature and open questions for future research. 📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)! www.sciencedirect.com/science/arti...

This Halloween, we have a spooky evolutionary story for you. The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41... Here’s why I love this work — and why I think you’ll enjoy it too. 👇

Rosa Lozano-Durán (@geminiteamlab.bsky.social), one of the newly elected EMBO members 2025, has introduced her research at the @embo.org Members' Meeting in Heidelberg. We are so proud of you! #plantsci

Game changer for cell-based plant genetics: the labs of Caixia Gao & Jin-Long Qiu have developed very efficient self-replicating vectors and they just published a very nice proof-of-concept paper. #plantscience www.science.org/doi/10.1126/...

JOB ALERT! Do you also love large ecological experiments? Become coordinator of our big new geo-biosphere experiment in @terra-cluster.org. 7-year position! Follow link for details. @gfoesoc.bsky.social @britishecologicalsociety.org @ecologicalsociety.bsky.social @uslter.bsky.social Please repost!

How do geminiviruses maximize their limited coding capacity? Our recent preprint uncovers splicing of viral transcripts as one more strategy used by this viral family. We show that RNA splicing is prevalent in the geminivirus TYLCV — and required for infectivity! www.biorxiv.org/content/10.1...

Have you noticed someone new here? 👇 Welcome @mpcontreras.bsky.social, our new junior group leader at the ZMBP! #newPI #plantscience #MPMI

Dear @dfg.de & @erc.europa.eu Why don't you do the same? What's stopping us from adopting this model to all tax-payer funded research in Europe? journals.plos.org/plosbiology/...

📢 Job alert! #PlantSciJob We are opening a Professorship (W1-TT) in Plant Biochemistry at the ZMBP @unituebingen.bsky.social Apply by October 17th Please spread the word! More info 👇 uni-tuebingen.de/fakultaeten/...

Another Preprint Pizza Party has come and passed! Students, postdocs and RAs from TSL and @johninnescentre.bsky.social gathered to discuss and review recent @biorxivpreprint.bsky.social articles 📝 Pizza kept the spirits high during this challenging task 🍕 #PreprintCommentClub #PreprintPizzaParty

BIK1-RIN4 complex links plant immunity and pathogen virulence https://www.biorxiv.org/content/10.1101/2025.09.03.673898v1

Amazing #CelebratingAlumni news this week (Thread) (1/3) Clemence Marchal @ClemMarchal received an @ERC_Research Starting Grant -- CooPAIRation "Optimised plant immune receptor pairs" erc.europa.eu/news-events/...

Dr. Joel Frohlich vom fMEG-Zentrum der Medizinischen Fakultät und Dr. Clémence Marchal vom @zmbp-tuebingen.bsky.social haben jeweils einen Starting Grant des @erc.europa.eu eingeworben! Herzlichen Glückwunsch! 👏 Mehr Infos: 👉 uni-tuebingen.de/universitaet... #ERCStartingGrants #Molekularbiologie

Can't believe my @thesainsburylab.bsky.social chapter is coming to an end! Feels like only yesterday I was starting my predoc with @kamounlab.bsky.social 🥲 Learned so much from several generations of TSL scientists, made some discoveries and a lot of friends! Time flies when you're having fun...

We just published: Why you should sequence your plasmids (and how to do it for free) Through @GetGenome scientists in 100 countries can access free whole-plasmid sequencing —giving researchers the confidence to move their experiments forward. medium.com/p/why-you-sh...

I just published: Data vs hypothesis driven research: the false dichotomy This post is adapted from a talk I gave @plantae_org Find out more 👇 medium.com/p/data-vs-hy...

I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/ www.biorxiv.org/content/10.1...

1/3 New preprint led by Shanshan Wang, in collaboration with the Timmermans lab. Several groups have presented sc/snRNA-seq analyses of Arabidopsis leaves after bacterial infection before. Is there anything left to discover? Turns out: Yes. #plantscience www.biorxiv.org/content/10.1...

Finally a method to identify plant RNA-binding proteins! 🧬 This enables so much new biology to discover from immunity to development! 🤯 🪴 Established by the incredible Victor Sanchez with @havandenburg.bsky.social @uva.nl Congratulations!!

Happy to share that our Helixer deeplearning-based annotation of 230 superasterid genomes is now online on @datadryad.bsky.social 💻🌱 doi.org/10.5061/drya... Check out how we used 69 of them to study the molecular evolution of a plant immune receptor network here! 👇

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity https://www.biorxiv.org/content/10.1101/2025.07.20.665670v1

I just published: Stop displaying journal names on your slides A mentoring event at a Congress called for better support of early-career scientists - but what followed sent mixed signals. This blog reflects on those moments and ends with a pledge. medium.com/p/stop-displ...

Anyone at #2025ISMPMI who didn't like my confocal microscopy, here's your chance to come and teach me how to do it better. I think you'll like the amazing team and kit.

Less than a week left to apply! 🌱💚

🚨 New @biorxivpreprint alert! 🚨 We are thrilled to share our latest findings—building on our earlier work on suppressors of helper NLRs of the NRC family—a Phytophthora infestans L-shaped effector captures resistosome assembly intermediates of tomato NRC3! www.biorxiv.org/content/10.1... 1/10

Excited to attend my 1st ISMPMI conference, and present our work on a paired wheat CNL/MLKL receptor mechanism! 🌾 Come chat to me at my poster on Tuesday, P-050! 📜 If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!

Chewing the fat with old colleagues @jiorgoskourelis.bsky.social #ismpmi2025

Up and ready! Find me at P-267 today for some molecular evolution and NLR biology! 🥬💻 You can also find the poster and preprint below 👇🏻 #2025ISMPMI

Preprint: “Structural modeling reveals viral proteins that manipulate host immune signaling” Using AI-guided structural modeling, we find new families of viral proteins that sequester or cleave host immune signaling molecules Congrats Nitzan Tal! www.biorxiv.org/content/10.1...

Kudos Madhu @JMadhuprakash, Mau @mpcontreras4 and the whole team for this beautiful structure and study! 😍 #EffectorWisdom #NLRbiology #PlantSci

Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges #AlphaFold3, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism. www.biorxiv.org/content/10.1...