Mauricio Contreras
@mpcontreras.bsky.social
📤 807
📥 226
📝 31
Junior Group Leader at
@zmbp-tuebingen.bsky.social
NLR and effector biology 🇦🇷
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Mauricio Contreras
Aude Bernheim
6 days ago
Hi everyone, a few years ago, we started a list of labs studying bacterial immunty for students, editors, conference organizers... (currently n=79). Update time ! Send me a message to 1) add your lab or others 2) Correct info
docs.google.com/spreadsheets...
#Phagesky
#Microsky
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Labs in bacterial immunity
https://docs.google.com/spreadsheets/d/1mKy0ALZSbGZsEmt3h20JNQ5MOpVsCQ276HybsMo-t4c/edit?gid=0#gid=0
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Cristina Barragan
7 days ago
My new Emmy Noether Group is recruiting! 🔬 Two PhD positions in plant pathogen evolution 🧬 Start: April 2026 (flexible) 📍 Dept. of Phytopathology & Plant Protection
@rstam.bsky.social
@uni-kiel.de
⏰ Apply by 15 Dec 2025 🔗 More info:
www.uni-kiel.de/personal/de/...
Do get in touch or share 😊
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Aktuelle Ausschreibungen
Aktuelle Ausschreibungen
https://www.uni-kiel.de/personal/de/stellen/extern/wiss
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Mauricio Contreras
6 days ago
We wrote a review 📖 on hydathode immunity! Learn how bacteria exploit hydathodes to access the vasculature and open questions for future research. 📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)!
www.sciencedirect.com/science/arti...
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Hydathodes at the forefront of plant immunity against vascular pathogens
Hydathodes are tiny plant organs that form an interface between the leaf surface and xylem vasculature. They facilitate excretion of xylem fluid under…
https://www.sciencedirect.com/science/article/pii/S1369526625001360
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Yasin Dagdas
10 days ago
This Halloween, we have a spooky evolutionary story for you. The brainchild of
@delaconcepcionjc.bsky.social
, Nick Irwin and our fantastic collaborators is now out in
@natplants.nature.com
www.nature.com/articles/s41...
Here’s why I love this work — and why I think you’ll enjoy it too. 👇
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Mauricio Contreras
ZMBP
17 days ago
Rosa Lozano-Durán (
@geminiteamlab.bsky.social
), one of the newly elected EMBO members 2025, has introduced her research at the
@embo.org
Members' Meeting in Heidelberg. We are so proud of you!
#plantsci
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PlantEvolution 🌱🌾
about 1 month ago
Game changer for cell-based plant genetics: the labs of Caixia Gao & Jin-Long Qiu have developed very efficient self-replicating vectors and they just published a very nice proof-of-concept paper.
#plantscience
www.science.org/doi/10.1126/...
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Oliver Bossdorf
about 1 month ago
JOB ALERT! Do you also love large ecological experiments? Become coordinator of our big new geo-biosphere experiment in
@terra-cluster.org
. 7-year position! Follow link for details.
@gfoesoc.bsky.social
@britishecologicalsociety.org
@ecologicalsociety.bsky.social
@uslter.bsky.social
Please repost!
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Stellenangebote: Universität Hohenheim
Aktuelle Stellenangebote der Universität Hohenheim.
https://www.uni-hohenheim.de/stellenangebote?tx_unijobs_joboffers%5Bjoboffer%5D=4313&tx_unijobs_joboffers%5Baction%5D=show&tx_unijobs_joboffers%5Bcontroller%5D=Joboffer&cHash=e7ae7a82d04f0d7f01b79edb41ac2534
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GeminiTeamLab
about 1 month ago
How do geminiviruses maximize their limited coding capacity? Our recent preprint uncovers splicing of viral transcripts as one more strategy used by this viral family. We show that RNA splicing is prevalent in the geminivirus TYLCV — and required for infectivity!
www.biorxiv.org/content/10.1...
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Pervasive splicing in a plant DNA virus
Viruses maximize their limited coding space through strategies that increase transcript and protein diversity. In mammalian viruses, splicing is a well-established mechanism for proteome expansion, ye...
https://www.biorxiv.org/content/10.1101/2025.10.01.679800v1
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Mauricio Contreras
ZMBP
about 1 month ago
Have you noticed someone new here? 👇 Welcome
@mpcontreras.bsky.social
, our new junior group leader at the ZMBP!
#newPI
#plantscience
#MPMI
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Yasin Dagdas
about 2 months ago
Dear
@dfg.de
&
@erc.europa.eu
Why don't you do the same? What's stopping us from adopting this model to all tax-payer funded research in Europe?
journals.plos.org/plosbiology/...
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Mauricio Contreras
ZMBP
2 months ago
📢 Job alert!
#PlantSciJob
We are opening a Professorship (W1-TT) in Plant Biochemistry at the ZMBP
@unituebingen.bsky.social
Apply by October 17th Please spread the word! More info 👇
uni-tuebingen.de/fakultaeten/...
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Mauricio Contreras
The Sainsbury Laboratory
2 months ago
Another Preprint Pizza Party has come and passed! Students, postdocs and RAs from TSL and
@johninnescentre.bsky.social
gathered to discuss and review recent
@biorxivpreprint.bsky.social
articles 📝 Pizza kept the spirits high during this challenging task 🍕
#PreprintCommentClub
#PreprintPizzaParty
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Mauricio Contreras
bioRxiv Plant Bio
2 months ago
BIK1-RIN4 complex links plant immunity and pathogen virulence
https://www.biorxiv.org/content/10.1101/2025.09.03.673898v1
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Sophien Kamoun
2 months ago
Amazing
#CelebratingAlumni
news this week (Thread) (1/3) Clemence Marchal @ClemMarchal received an @ERC_Research Starting Grant -- CooPAIRation "Optimised plant immune receptor pairs"
erc.europa.eu/news-events/...
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The ERC awards €761m to the next generation of scientists in Europe
The European Research Council (ERC) has selected 478 early-career researchers across Europe to receive this year’s Starting Grants. With a total funding of €761 million, these grants support excellent...
https://erc.europa.eu/news-events/news/erc-2025-starting-grants-results
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Mauricio Contreras
Universität Tübingen
2 months ago
Dr. Joel Frohlich vom fMEG-Zentrum der Medizinischen Fakultät und Dr. Clémence Marchal vom
@zmbp-tuebingen.bsky.social
haben jeweils einen Starting Grant des
@erc.europa.eu
eingeworben! Herzlichen Glückwunsch! 👏 Mehr Infos: 👉
uni-tuebingen.de/universitaet...
#ERCStartingGrants
#Molekularbiologie
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Can't believe my
@thesainsburylab.bsky.social
chapter is coming to an end! Feels like only yesterday I was starting my predoc with
@kamounlab.bsky.social
🥲 Learned so much from several generations of TSL scientists, made some discoveries and a lot of friends! Time flies when you're having fun...
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2 months ago
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Sophien Kamoun
3 months ago
We just published: Why you should sequence your plasmids (and how to do it for free) Through @GetGenome scientists in 100 countries can access free whole-plasmid sequencing —giving researchers the confidence to move their experiments forward.
medium.com/p/why-you-sh...
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Why you should sequence your plasmids (and how to do it for free)
Through GetGenome, scientists in 100 countries can access free whole-plasmid sequencing — removing barriers, improving quality control…
https://medium.com/p/why-you-should-sequence-your-plasmids-and-how-to-do-it-for-free-6937792132b9?source=social.tw
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Sophien Kamoun
3 months ago
I just published: Data vs hypothesis driven research: the false dichotomy This post is adapted from a talk I gave @plantae_org Find out more 👇
medium.com/p/data-vs-hy...
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Data vs hypothesis driven research: the false dichotomy
This post is adapted from a talk I gave at the Plantae Presents webinar More Money, More Data: Data-Driven versus Hypothesis-Driven…
https://medium.com/p/data-vs-hypothesis-driven-research-the-false-dichotomy-2b026e5007e6?source=social.tw
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Tera Levin
3 months ago
I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/
www.biorxiv.org/content/10.1...
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Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium
Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...
https://www.biorxiv.org/content/10.1101/2025.08.01.668227v1
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PlantEvolution 🌱🌾
3 months ago
1/3 New preprint led by Shanshan Wang, in collaboration with the Timmermans lab. Several groups have presented sc/snRNA-seq analyses of Arabidopsis leaves after bacterial infection before. Is there anything left to discover? Turns out: Yes.
#plantscience
www.biorxiv.org/content/10.1...
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Mauricio Contreras
3 months ago
Finally a method to identify plant RNA-binding proteins! 🧬 This enables so much new biology to discover from immunity to development! 🤯 🪴 Established by the incredible Victor Sanchez with
@havandenburg.bsky.social
@uva.nl
Congratulations!!
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AmirAli Toghani
6 months ago
Happy to share that our Helixer deeplearning-based annotation of 230 superasterid genomes is now online on
@datadryad.bsky.social
💻🌱
doi.org/10.5061/drya...
Check out how we used 69 of them to study the molecular evolution of a plant immune receptor network here! 👇
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Mauricio Contreras
bioRxiv Plant Bio
4 months ago
A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity
https://www.biorxiv.org/content/10.1101/2025.07.20.665670v1
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Sophien Kamoun
4 months ago
I just published: Stop displaying journal names on your slides A mentoring event at a Congress called for better support of early-career scientists - but what followed sent mixed signals. This blog reflects on those moments and ends with a pledge.
medium.com/p/stop-displ...
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Stop displaying journal names on your slides
A mentoring event at a scientific Congress called for better support of early-career scientists — but what followed sent mixed signals…
https://medium.com/p/stop-displaying-journal-names-on-your-slides-b87f0501d0f3?source=social.tw
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Sam Mugford
4 months ago
Anyone at
#2025ISMPMI
who didn't like my confocal microscopy, here's your chance to come and teach me how to do it better. I think you'll like the amazing team and kit.
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Margot Smit
4 months ago
Less than a week left to apply! 🌱💚
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Jogi Madhuprakash
4 months ago
🚨 New @biorxivpreprint alert! 🚨 We are thrilled to share our latest findings—building on our earlier work on suppressors of helper NLRs of the NRC family—a Phytophthora infestans L-shaped effector captures resistosome assembly intermediates of tomato NRC3!
www.biorxiv.org/content/10.1...
1/10
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Saskia Hogenhout
4 months ago
www.biorxiv.org/content/10.1...
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Effector Innovation in Genome-Reduced Phytoplasmas and Other Host-Dependent Mollicutes
Obligate host-associated bacteria with reduced genomes, such as phytoplasmas, face strong evolutionary constraints, including metabolic dependence on hosts, limited horizontal gene transfer (HGT), and...
https://www.biorxiv.org/content/10.1101/2025.07.14.664665v1
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Josh Bennett
4 months ago
Excited to attend my 1st ISMPMI conference, and present our work on a paired wheat CNL/MLKL receptor mechanism! 🌾 Come chat to me at my poster on Tuesday, P-050! 📜 If you miss my poster session, I will be talking in: Crop resistance genetics and genomics on Wednesday - 16:25-16:35!
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Sam Mugford
4 months ago
Chewing the fat with old colleagues
@jiorgoskourelis.bsky.social
#ismpmi2025
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Mauricio Contreras
AmirAli Toghani
4 months ago
Up and ready! Find me at P-267 today for some molecular evolution and NLR biology! 🥬💻 You can also find the poster and preprint below 👇🏻
#2025ISMPMI
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Sorek Lab
4 months ago
Preprint: “Structural modeling reveals viral proteins that manipulate host immune signaling” Using AI-guided structural modeling, we find new families of viral proteins that sequester or cleave host immune signaling molecules Congrats Nitzan Tal!
www.biorxiv.org/content/10.1...
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Sophien Kamoun
4 months ago
Kudos Madhu @JMadhuprakash, Mau @mpcontreras4 and the whole team for this beautiful structure and study! 😍
#EffectorWisdom
#NLRbiology
#PlantSci
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Simon Snoeck
4 months ago
Shedding light on the structure-function mechanisms of LRR-RPs. Our research merges
#AlphaFold3
, years of literature and functional validation to reveal diverse ligand-binding mechanisms and a conserved co-receptor association mechanism.
www.biorxiv.org/content/10.1...
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Thrilled to share our latest preprint! This work started during my PhD and was finished together with
@jmadhuprakash.bsky.social
. We found a Phytophthora infestans L-shaped effector that bridges a host TOL protein to activated NLRs to suppress immunity!
www.biorxiv.org/content/10.1...
1/15
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4 months ago
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bioRxivpreprint
4 months ago
An effector from the potato late blight pathogen bridges ENTH-domain protein TOL9a to an activated helper NLR to suppress immunity
https://www.biorxiv.org/content/10.1101/2025.07.06.663370v1
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bioRxiv Bioinfo
4 months ago
Structural motif search across the protein-universe with Folddisco
https://www.biorxiv.org/content/10.1101/2025.07.06.663357v1
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Martin Steinegger 🇺🇦
4 months ago
Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄
www.biorxiv.org/content/10.1...
🌐
search.foldseek.com/folddisco
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Tatsuya Nobori
4 months ago
Hot off the printer! Our lab will be introducing PHYTOMap to the MPMI community. Interested in spatially mapping both microbiomes and plant gene expression? Come see our posters at
#2025ISMPMI
P-315 by
@siyusong.bsky.social
P-441 by
@hsuanpai.bsky.social
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Pingtao Ding (he/him)
4 months ago
Cell-type-specific execution of effector-triggered immunity Our new preprint is online, 1 July⬇️ With
@himanshuchhillar.bsky.social
@leonardojo.bsky.social
Amey Redkar
@kaisakajala.bsky.social
@jonathandgjones.bsky.social
For early readers & community feedback🙏🏼
#openscience
@erc.europa.eu
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bioRxiv Plant Bio
4 months ago
Cell-type-specific execution of effector-triggered immunity
https://www.biorxiv.org/content/10.1101/2025.06.28.662111v1
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Joaquín Sevilla
5 months ago
Desde Lysenko en los 1930 no se veía una interferencia tan mortífera entre la ideología y el conocimiento científico...
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Isabel Monte
6 months ago
Thanks to
@thesainsburylab.bsky.social
Postdocs for the invitation and for the exciting scientific discussions! What a great day! 😊
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Sebastian Schornack
6 months ago
If you are member of the IS-MPMI society, you will have received the option to vote for the next president and members of the board of directors. This is an encouragement to vote. Also, I am running for one of the two director positions.
www.ismpmi.org/members/Page...
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The Plant Cell
6 months ago
📣 Join us on May 30 at 9 EDT, for a The Plant Cell panel discussion focusing on “Translational Research from Arabidopsis to Crop Plants and Beyond".🌱 👉Learn more and register at
blog.aspb.org/may-30-plant...
.
#plantscience
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Hsuan Pai 白暄
8 months ago
Childhood happiness thanks
@mpcontreras.bsky.social
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Mauricio Contreras
eurobioimaging.bsky.social
8 months ago
With
@agroserv.bsky.social
funding,
@delaconcepcionjc.bsky.social
visited
@embl.org
Imaging Centre to use cryo-EM & CLEM to see how fungal pathogens penetrate plants with unprecedented results.🔬🌾 Learn more🔽
eurobioimaging.eu/news/imaging...
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Imaging to combat crop diseases: How Euro-BioImaging transforms agricultural research
Between 20-40% of global food crop production is lost each year due to plant pests and pathogens, highlighting the urgency for scientific research in this area. Disease losses are particularly…
https://eurobioimaging.eu/news/imaging-to-combat-crop-diseases-how-euro-bioimaging-transforms-agricultural-research/
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Baptiste Castel
8 months ago
🔗 Preprint alert:
www.biorxiv.org/content/10.1...
🧵 New insights into plant immunity: using ferns to understand evolution! 🌱✨🌿 Excited to share my first (but not last) published research at
@lrsv-toulouse.bsky.social
. A THREAD … [1/9]
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Exploring fern pathosystems and immune receptors to bridge gaps in plant immunity
Land plants include angiosperms, bryophytes, lycophytes and ferns, each of which may deploy distinct strategies to resist pathogens. Here, we investigate fern-pathogen interactions by characterizing n...
https://www.biorxiv.org/content/10.1101/2025.03.18.643875v1
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Sophien Kamoun
9 months ago
We have a Winner! Congrats AmirAli @amiralito_ for winning the 2024 ASAPbio @ASAPbio_ Poster Competition! So proud of our team's embrace of transparent and early sharing of data, ideas and protocols. The future is bright!
#openscience
asapbio.org/announcing-t...
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Sophien Kamoun
9 months ago
Here is a link to the poster: Evolutionary diversification of protein-protein interaction interfaces: A case study on an NLR immune receptor network
#ASAPbio
#openscience
doi.org/10.5281/zeno...
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