Day 1 of the Mendel Early Career Symposium! 100 international researchers gathered for networking, engaging talks & posters, keynote by @emmanuellebayer.bsky.social, & workshop on ChimeraX/AlphaFold. Thanks to the sponsors for supporting expanding horizons in #PlantBiology. #Mendel_ECR_26

#ASPBPlantCellTuesday #AuthorProfile #ICYMI

#ASPBPlantCellTuesday #AuthorProfile #ICYMI

The moles had a party last night. Probably Eurovision….

Irises this morning

Excellent thread on the exciting advances in vaccine technology for cancer treatment. So important this work is supported internationally. Huge potential. 👇

Super basic but key foundation to all this: TNBC is called this because the cancer is negative for a triple of markers (HR, HER2, and PR) that have associated treatments. So it makes total sense that if we use modern methods to find what the tumor is positive for, we can use those to treat it.

Happy birthday to x-ray #crystallographer Dorothy Mary Crowfoot Hodgkin (née Crowfoot, 1910-1994), Nobel laureate in #chemistry for her models of biomolecules like penicillin, vitamin B12 & insulin. 🧪🐡👩🏼‍🔬 #histsci She was “captured for life by chemistry and crystals,” in childhood, 1 of 2 girls 🧵

Today our group hosted Sierra Cole from the laboratory of Amy Gladfelter at Duke - talking about the fascinating biology of RNA-binding proteins and condensate formation @thesainsburylab.bsky.social

Great talk today from Gary Ruvkun - a tour de force through microRNA biology and some fascinating insights into tRNA modifications and their potential biological function. Amazing @thesainsburylab.bsky.social

Hugely productive symposium between @thesainsburylab.bsky.social and @ilri.org hosted by Appolinaire Djikeng. We made great progress in identifying collaborative science that can make an impact in the Global South.

Developing durable potato late blight resistance for sub-Saharan Africa in Uganda @jonathandgjones.bsky.social @thesainsburylab.bsky.social @ilri.org

“Biology can finally move at the speed of pathogen evolution” - looking forward to a near era in plant disease control @kamounlab.bsky.social @thesainsburylab.bsky.social

Great to be in Nairobi to explore challenges in the Global South and how @thesainsburylab.bsky.social and @ilri.org can work together to address them.

Savannah encounters I 🇰🇪

AI-guided discovery of atypical protein assemblies https://www.biorxiv.org/content/10.64898/2026.05.03.722499v1

These dogs are trained to find cheetah poop 🐆 💩 @Action4Cheetahs www.actionforcheetahs.org

SNI is a scalable way to discover atypical protein assemblies. Works on any family with prior structural knowledge. Working on a complex? Give it a try. We’d love to see what you find! Happy to discuss collaborations as well :) (8/n) 💻 github.com/amiralito/So...

Huge thanks to an incredible team for making this happen! And to @googledeepmind.zpravobot.news.ap.brid.gy for the co-scientist collaboration. (9/n) doi.org/10.64898/202...

Leader retreat @TheSainsburyLab Kapiti @ILRI 🇰🇪

It’s giraffe week 🇰🇪

New study with @imperialcollegeldn.bsky.social @imb-as.bsky.social shows that NRG1 binds chloroplasts to trigger plant immunity, challenging the view of resistosomes working at the plasma membrane 🌱 "We have only scratched the surface of plant immunity" @kamounlab.bsky.social

🌱 From The Plant Cell: Identifying an aberrant RNA trigger reveals why some engineered genes shut down, guiding design of more stable traits in crops. (Richard Michelmore , Blake C Meyers) ▶️ academic.oup.com/plcell/artic... #PlantScience #PlantBiology

We are thrilled to announce the election of 120 members and 25 international members to the National Academy of Sciences in recognition of their distinguished and continued achievements in original research. Congratulations to our new #NASmembers and welcome to the Academy! 🎊

New preprint! We asked a simple question: How do very different activating adaptors all activate dynein? Turns out: same architecture, wildly different implementations 🧵👇 doi.org/10.64898/202...

🎉 📰 Very happy to share the journal publication of our manuscript "Plant-associated fungi co-opt ancient antimicrobials for host manipulation"! #ScienceAdvancesResearch @science.org @teamthomma.bsky.social www.science.org/doi/10.1126/...

New layer of plant immune system "membrane mechanosensing immunity (MSI), a third layer of cell surface immune signaling" is nicely demonstrated by @julien-gronnier.bsky.social group Cool finding! Congratulations!

✍️ New preprint from the @minclab.bsky.social 📃 Mechanosensation Promotes Local Cell Wall Repair 🔗 www.biorxiv.org/content/10.6...

Bad news Monday 🧪 RIP Peter Raven. news.mongabay.com/2026/04/pete... news.mongabay.com/2007/03/biod... is a good interview from several years back. 🧪

Curiosity is the only addiction I would recommend @TEDx #TEDxPashaStreet

Big opportunities for researchers 🌍 We are investing nearly €400 million to help researchers share their work and collaborate with the best scientific teams across the EU. The 2026 Marie Skłodowska-Curie Actions Postdoctoral Fellowships are now open. More: link.europa.eu/PNxpxw

Moths, resistosomes and more @TEDx #TEDxPashaStreet

Fascinating Chatt Lecture today by Feng Shao who identified gasdermin‑D, the executioner of pyroptosis, & defined gasdermins as pore‑forming protein family that underlies this mode of cell death in innate immunity & anti‑tumor responses. @johninnescentre.bsky.social @thesainsburylab.bsky.social

The richest man owns X. The second and fourth richest men control Google. The third richest man owns The Washington Post. The fifth richest man owns Facebook, Instagram, and WhatsApp. And now the sixth richest could soon take over both Paramount and Warner Bros. See the problem here?

A review on Super-resolution Structured Illumination Microscopy (SIM) to study endocytosis: pubs.acs.org/doi/10.1021/... Featuring our live-cell SIM of proximal axons showing frozen clathrin-coated pits within clearing of the spectrin mesh (doi.org/10.1126/scie...)

We are hiring! We’re excited to recruit a postdoc to our lab at UC Davis to work on plant immune engineering and single-cell analyses of plant pathogen interactions. Apply by June 1. Please repost. www.coakerlab.org/postdoctoral...

I just published: Leave the red shirt out: Scientists, stop complicating the story Scientists are brilliant at finding details. We are less brilliant at knowing which details to shut up about. medium.com/p/leave-the-...

Another day another beautiful inflammasome structure! "Structure of zebrafish NLRP3 reveals a novel mode of inflammasome activation" by Dopslaff et al. www.biorxiv.org/content/10.6...

Beautiful work by @franbottanelli.bsky.social lead by @probablycarmen.bsky.social now out. Was fun to contribute!

We just received funding for a 2yr postdoc position on cryoEM of fungal gpcrs. Official call will open soon. Contact me if you‘re interested!

Humbling to give a cell biology talk in the centre in Szeged where Brúnó Straub first isolated and named actin. He was working in Albert Szent‑Györgyi’s muscle biochemistry group, which had just won the 1937 Nobel Prize for isolation of Vitamin C. Both commemorated here.

Great visit to the Biological Research Centre of Szeged in (a very happy) Hungary - excellent discussions on fungal developmental biology with László Nagy and team.

impressive!

#IS-MPMI Interested in how discoveries in the plant-microbe field have been translated to the real world? Check out our YouTube channel. We’ve just posted the ISMPMI Translational Science Workshop from 2021. Available to the public for the first time. www.youtube.com/@is-mpmi3587

BREAKING: A Closer Look at the King of Planets. 🪐🛰️ NASA has just released a new perspective of Jupiter so sharp it’s almost impossible to comprehend. Those intricate, marble-like swirls aren't just clouds—they are colossal storms, many of which could swallow Earth whole. 🌍🌪️

~12 years after we coined it EPP1 with @oswaldovaldesl.bsky.social one afternoon when we were postdoc with @jeanmichelane.bsky.social! Congrats @melaniekrich.bsky.social @tatiana-vernie.bsky.social et al. for the hard work! EPP1 is the fourth member of the Common Symbiosis Pathway 🍄🌱!

Check out this exciting postdoc opportunity at @johninnescentre.bsky.social to work with the amazing @hassansalem.bsky.social and @berasymbionts.bsky.social on the developmental and molecular basis of insect–microbe symbiosis. I’m excited to be part of this collaborative project!

Very proud to share our new paper led by Mathias Brands from my team at @UniCologne! With Markus Pauly team @HHU. Host-adapted enzymatic deconstruction of acetylated xylan limits immune activation and facilitates mutualistic colonization of monocot roots: Molecular Plant www.cell.com/molecular-pl...

I’ve read all the biographies & Crick’s autobiography too, but I feel like I got to know the real person in this book. A masterpiece, because of the brilliant writing and research of @matthewcobb.bsky.social

Flying over Norwich Research Park this morning. The start of the HP3 project providing new infrastructure to @johninnescentre.bsky.social and @thesainsburylab.bsky.social is visible now as well as the new data centre by @earlhaminst.bsky.social