🚨🚨Last day to register for the next annual meeting of Club Exocytose-Endocytose !!!🚨🚨 Invited speakers: M. Stroeber, G. D'Angelo and @christlet.bsky.social 📍 Centre Paul-Langevin, Aussois, France 📅 May 27–29, 2026 Get ready for exciting science!! Registration here exoendo.org/evenement/28...

New perspective on caveolae www.nature.com/articles/s41...

It was fun writing this with David @dgershlick.bsky.social! Check it our if you want to hear our view on small #GTPases networks in endosomal trafficking :) part of the themed issue on Membrane trafficking edited by @fromme-lab.bsky.social and Philippe Chavrier www.sciencedirect.com/science/arti...

Preprint 🧵! I’m really excited to introduce BIGSMALL, an interleaved multi-magnification cryo-ET scheme bridging molecular and cellular scales in a single acquisition! BIGSMALL = 𝐁road 𝐈nformation 𝐆athering 𝐒trategy by 𝐌ultiscale 𝐀cquisition of lame𝐋𝐋a www.biorxiv.org/content/10.6... (1/6)

Interested in caveole and/or lipid metabolism? We have two master thesis projects available in the lab @unipotsdam.bsky.social starting September or October. For more details 👇 www.matthaeus-lab.de/post/04-2026...

1/9 🚨 New paper out in Nature Metabolism! Chapter 2 of our mitochondria zonation story (following our 2024 Nature Communications work). We asked how zonated liver mitochondria adapt when lipid flux surges. 🧵👇 www.nature.com/articles/s42...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...

Methods in Enzymology, Vols 726-728: Lipids & Membranes Vol 726: Detection by Imaging & Lipidomics www.sciencedirect.com/bookseries/m... Vol 727: Dynamics & Interorganelle Transport www.sciencedirect.com/bookseries/m... Vol 728: Metabolism, Lipidation, & Lipid-Protein Interactions: coming soon!

Awesome paper and super useful resource of CRISPR-based screens to identify regulators of #LipidDroplet biology under different metabolic conditions: crisprlipid.org

Final week to apply: GSO Leadership Academy 10 The GSO Leadership Academy is an interactive program designed to support researchers who want to develop leadership skills for academia and beyond. 📅 Application deadline: March 1, 2026 🔗 More information: gsonet.org/foerderprogr...

Join us next Tuesday for the next @dgz.bsky.social workshop on #trafficking and EVs! Spread the word please!

Structural basis of caveolin-driven membrane bending www.biorxiv.org/content/10.6...

Lipids challenge ligands to control receptors The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in. 🔗 buff.ly/G1Zl6cZ

Methods should be used as widely as possible, so here is our detailed lipid imaging protocol, written with @martinba99.bsky.social and Chia-Yi (Christine) Chou authors.elsevier.com/a/1mU4XHRzCb... in Methods in Enzymology. Everything you need to know to do it yourself is in there -

Triglyceride/Cholesterol Ester Ratio Encodes Lipid Droplet Size and Diversity https://www.biorxiv.org/content/10.64898/2026.01.21.700800v1

Distinct neurons, distinct functions 🧠🟤 Our Nature Metabolism paper (now out!) shows that separate sympathetic projections to brown adipose tissue independently control thermogenesis and glucose tolerance. Congrats Daniele Neri and team 🥳 www.nature.com/articles/s42...

With so many great reviews on LDs already out, do we need another? Sarah @cohenlaboratory.bsky.social and I were approached by @natrevmcb.nature.com to do a review on LD heterogeneity and inter-organelle contacts...topics in reviews, but not a focus. Fun project! www.nature.com/articles/s41...

Happy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7) www.biorxiv.org/content/10.6...

I was part of the GSO Leadership Academy in 2023 and learned a LOT! I can highly recommend to apply. Still using techniques & advices in my everyday young PI life. And the best - it comes with an amazing peer group!

I've been waiting for this Titeca et al. story from Anne-Claude Gavin's lab to come out: A systematic, comprehensive analysis of lipid transfer protein cargo selection, a truly massive undertaking. What a time to work in lipid biology. Cool stuff every few days. www.nature.com/articles/s41...

Thrilled to share our latest study, led by @reikatei.bsky.social, in @natchembio.nature.com! We began by asking a simple question—how do cells know if they have too much of a lipid in a particular membrane, and how do they respond to rectify this imbalance? www.nature.com/articles/s41... More info 👇

Registration is open for the FASEB #LipidDroplet meeting in Scottsdale, July 26-30! This is THE premier North American conference on LDs, you do not want to miss it!

Great Thread/ summary about interesting lipid related papers of 2025 👇

To all lipid-curious cell biologists: check out this comprehensive overview of lipid-based methods by @gerryhammond.bsky.social and colleagues in @jcb.org — a school of Babel fish for #lipidtime: rupress.org/jcb/article/...

Blog post: Just quit Quitting projects in science is hard, but we should be doing a lot more of it. open.substack.com/pub/arjunraj...

Researchers have identified the protein SCoR2 as a potential drug target for obesity and hepatic steatosis in studies of mice, showing that it prevents fat accumulation and weight gain. Learn more in #ScienceSignaling: https://scim.ag/4p5KxNe

‼️🚨Hi all! The next Bioc Soc Membrane Contact Site Meeting will be in Chepstow, UK 28-30th Sept 2026. Fantastic speakers with talk slots still available. Sign up & abstract submission now open - limited spaces so register early! Hope to see you all there. Please share + RT 🙏

Another interesting new paper showing cellular insights in caveolae mediated fatty acid uptake by Richard Lundmarks lab and @robparton.bsky.social they show caveolae -ER contact sites that might fuel fatty acids from the plasma membrane into the ER. Very exciting!

Great opportunity for a Postdoc interested in cellular high resolution imaging: amazing lab & team, amazing campus & resources! And summer times starts early in DC ☀️I can highly recommend 👇

⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...

Excited to share that as my group launches across Karolinska Institutet and the University of Helsinki, we’re recruiting postdocs and research assistants to study the nanoscale architecture of lipid flux using in-cell structural biology approaches, including cryo-ET and cryo-CLEM

Textbooks said neurons don’t burn fatty acids for energy🤔. Our study delivers the first in vivo demonstration that fatty acid oxidation in defined memory neurons fuels memory formation. Closing chapter of my PhD 🥳, out today in Nature Metabolism💥 @natmetabolism.nature.com

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Ups we did it again! Please mark your calender. EMBO Workshop “Lipid Code to Life”, taking place September 7–11, 2026, in Dresden, organized by Maria Fedorova, @lipid.bsky.social, Valerie O'Donnell, @holthuislab.bsky.social and @molcellbiophys-lab.bsky.social 🥳 Retweets = lipidlove

💥I am excited to present our first research paper from the lab about caveolae lipid trafficking 🎉 Led by my fantastic PhD candidate @estherocket.bsky.social Here we looked into caveolae mediated dietary lipid uptake and how this process is mechanistically facilitated 👇 1/n

In our latest issue, Kerry-Anne Rye and colleagues Review HDL metabolism and function in diabetes mellitus (£) go.nature.com/495jFIA #EndoSky #MedSky

Please RT‼️ #TenureTrack position @zmbh.uni-heidelberg.de one of the best #proteostasis research centres in the world. www.nature.com/naturecareer...

The fun leaving your body the moment you're done with the science and it's time to get it published

And the saga continues! Our collaborative work with outstanding Justin Korfhage & Thomas Melia’s lab in PNAS shows that ATG2A transfers triglycerides and does so bidirectionally! An exciting twist in our understanding of lipid transport. Definitely worth a deep read: www.pnas.org/doi/10.1073/...

In this Protocol you will find comprehensive guidance for researchers, including those with limited electron microscopy experience, on the effective use of genetically encoded, multichannel EM-capsulin reporters for both fluorescence microscopy and EM workflows. @natprot.nature.com 🧪 🔬

Very exciting Postdoc positions available 👇

Junior professor position at the University of Kaiserslautern! Our Department of Biology is seeking a colleague working with microalgae. This is a wonderful place to do wonderful science with great people! Please, repost :) Further details: jobs.rptu.de/jobposting/1...

Know the difference.

Thrilled to share our latest work showing that the bridge lipid transport protein ATG2A transfers diacylglycerol (DAG), and some TAG/PA, from the ER to LDs, thereby recruiting DGAT2 to drive local TAG synthesis, promoting LD expansion while protecting ER membranes. www.nature.com/articles/s41...

The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility

Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis. Learn more this week: https://scim.ag/4nFEGO7

#Throwback 🧪 REVIEW | Futile lipid cycling: from biochemistry to physiology C Wolfrum et al.

Required reading for cell biologists to get a sense of basic statistical principles! www.nature.com/articles/s41...

Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...

#ACSChemBio and #Biochemistry invite submissions to a special issue on Lipids and Lipidation guest edited by @chembiobryan.bsky.social and me! Find details in the #CallforPapers and submit your exciting findings to one of these journals by May 31, 2026. axial.acs.org/chemical-bio... #lipidtime