In this Protocol you will find comprehensive guidance for researchers, including those with limited electron microscopy experience, on the effective use of genetically encoded, multichannel EM-capsulin reporters for both fluorescence microscopy and EM workflows. @natprot.nature.com 🧪 🔬

Happy to be attending the Cellular therapy and immunotherapy conference 2025 in Hangzhou. I’m looking forward to learning about the latest developments in the field! 🧪 #medsky mm.sciconf.cn/en/minisite/...

Longer walks linked with less mortality and cardiovascular risk compared with short bouts of physical activity @annalsofim.bsky.social www.acpjournals.org/doi/10.7326/...

Something to think about when talking to your favourite AI system: How to write effective prompts for large language models www.nature.com/articles/s41...

🧵🚨 The UK’s independent scientific bodies are highly vulnerable to politicisation - over the past 5 months I've been working with @martinmckee.bsky.social to map out their vulnerabilities and it's not good news. Today our report is published! www.ucl.ac.uk/policy-lab/n... 1/11

After a long pause, I've just done another England Covid & NHS update as we head into the autumn/winter season. TLDR: we're in a significant Covid wave now, the NHS is stretched, get boosted if you're eligible. christinapagel.substack.com/p/england-is...

🧠📈 Nerd-chic 💙

Congratulations to all three winners! Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks” We are honoured to have a Nature Protocol from Prof. Yaghi rdcu.be/eJ0Es www.nature.com/articles/s41...

BREAKING: The Nobel Prize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks” Stay tuned for more. #NobelPrize

Good to know: There is a free online training course for peer review from Nature Masterclasses masterclasses.nature.com/focus-on-pee...

When discussing content proposals for @natprot.nature.com with potential authors I often end up covering the wide reach of our journal. Often researchers are interested in examples of articles which have seen wide uptake, accesses and use from the scientific community. Here, a🧵of readcube links: 🧪🎓

Bioinspired in-sensor computing devices can process information at sensory terminals by leveraging physical principles, thereby reducing latency and energy consumption during computation while simultaneously enhancing the efficiency of data processing and real-time analysis. 🧪 @natprot.nature.com

How can we make sure that studies using transcranial electric stimulation (tDCS, tACS, etc.) are interpretable and reproducible? This new work is a consensus stement about what information is needed when reporting tES studies: www.nature.com/articles/s41...

Transcranial electrical stimulation (tES) has gained substantial momentum as a research and therapeutic tool; however, it suffers from challenges related to reproducibility and quality assessment due to the absence of standardized reporting practices. @natprot.nature.com 🧪🧠 #imaging #radiology

In this Protocol, Guosheng Song and co-authors provide instructions for the synthesis of trianthracene derivative (TD) nanoparticles with ultrasound-induced luminescence properties. @natprot.nature.com 🧪🔬 #imaging

The coupling of ion-exchange chromatography with mass spectrometry via electrochemical ion suppression creates a technique for the analysis of highly polar and ionic compounds with applications in environmental chemistry, food chemistry, forensics, cell biology and, more recently, metabolomics. 🧪

The versatility of lanthanide-doped near-infrared (NIR, 700–1,700 nm) luminescent nanoparticles makes them valuable tools across scientific and technological fields, from bioimaging to information security. @natprot.nature.com 🧪 #materials #imaging

Thermal scanning-probe lithography (tSPL) is a fabrication technique which can pattern mathematically defined landscapes with nanoscale dimensions. This protocol describes how to structure and optimize nanomaterials with tSPL with a software package to analyze topographic data. @natprot.nature.com 🧪

This protocol provides the instructions to automating key steps, including data preprocessing, model fine-tuning and evaluation for single-cell generative pretrained transformer (scGPT) using Python function wrappers within computing clusters and Jupyter notebooks. @natprot.nature.com 🧪

"The world has changed" say researchers who decided to leave the US. Having relocated to China a year ago with my family, the stories in this article resonate with us. Stereotypes were never true in the first place, and today we get to embrace that change and help write a new chapter.👏 @nature.com

Lymph node metastatic spread is hard to study due to the unpredictable characteristics of tumour cells' migration. The @retickerflynn.bsky.social lab here explains how to control LN metastases in mice in a spontaneous or a spatially constrained experimental model @natprot.nature.com #medski 🧪

Noble metal aerogels (NMAs) combine the physicochemical properties of nanostructured metals with the self-standing porous architecture of aerogels. NMAs have potential in #catalysis, #sensing and other applications in fundamental and applied sciences. @natprot.nature.com 🧪 #materials

I don’t usually do wordle anymore but saw Wordle X was trending over there… what’s the big deal? 🤣🤣🤣 Wordle 1,452 6/6 ⬜⬜🟨⬜⬜ 🟨⬜🟨⬜🟩 🟩🟩⬜⬜🟩 🟩🟩⬜⬜🟩 🟩🟩⬜⬜🟩 🟩🟩🟩🟩🟩

Cancer Research UK today published a report which highlights changes in cancer survival rates over the last 50 years. Many headlines (like this one from the Guardian) have chosen to report the ‘doubling of cancer survival rates’ since the 1970s. But that's misleading... 1/18

If you are interested in radiosynthesis and clinical quality control procedures then you can check out our new protocol on clinical grade lutetium-177-labeled theranostic agents 🧪 #medsky #radsky #pharmasky #pharmasky @natprot.nature.com

Simply staggering and a devastating blow to scientific and medical research in the US

Sources: Harvard University just filed a motion related to the Trump administration's revocation certification to accept foreign students. This revocation affects 7,000 visa holders.

In this Perspective, we discuss how the experience from Independent SAGE may help develop science advice groups for future public health emergencies and improve science communication efforts with the public. The article is now free to access!

Our May issue is live and includes an interesting piece written by @independentsage.bsky.social and published in December, discussing their mission and organization during Covid rdcu.be/d3n6s 🧪 @natprot.nature.com

The reason why @independentsage.bsky.social were able to identify and respond to the Immensa testing scandal was because we were looking at the data and listening to local communities who were experiencing the problem. #CovidInquiry

We’re excited to share our latest Nature Protocols paper, which presents a detailed protocol for achieving optical transparency in live mice using tartrazine: nature.com/articles/s41...

Finally out! This article from Guosong Hong's lab should be of interest to those who perform in vivo imaging: make your mice optically transparent! I have had so many people ask me about this method and now the protocol is available: 🧪🔬 #imaging @natprot.nature.com

An important point: If you share your protocol in a preprint server or in protocols repository like protocols.io you can still publish your protocol in a peer-reviewed journal like Nature Protocols at a later date.

In this Tools of the Trade article, PhD student Jing Ming explains how neutron total scattering can be used in fuel cell researcher

A year ago, global imaging leaders and funders met at @hhmijanelia.bsky.social to discuss #microscopy dissemination to underserved communities and the potential solutions. Are the challenges a misstep or a missed step? Here is the white paper to address that question. tinyurl.com/y6ycehzf

Our @nature.com paper is out! Bringing together 2 major theories of consciousness - Integrated Information Theory (IIT) and Global Neuronal Workspace Theory (GNWT) - in an unprecedented collaboration. Here’s the story of how we advanced theory testing in neuroscience www.nature.com/articles/s41...

Spatial imaging is a striking recent development which facilitates the localization of molecular targets in biological samples. Our collection covers a range of such approaches: 🧪 🔬 @natprot.bsky.social

When the conference organizers ask if you can send in your slides a week in advance

400 years ago, botanist Giovanni Faber, a member of the Lyncean Academy in Rome, wrote to Prince Federico Cesi, the Academy's founder, introducing the term "microscope" to describe an instrument created by Galileo Galilei. We have curated 6 Collections covering advances in microscopy 🧪 🔬

On 13 April 1625 a letter, authored by Johann Faber in Rome, first described an instrument built by Galileo as a "microscope". We shine some light on the value that developments in microscopy have provided to scientific research over the past 400 years, almost to the day. @natprot.bsky.social 🧪 🔬

I see that a recent article in a notable journal is being, in my opinion, vastly misinterpreted on socials and media outlets. In today's latest attempt at putting facts before hype, let me link the statement from the American College of Radiology: 🧪 #medsky #neuroimaging #radiology #cancer

A biochemical approach for the characterization of pathological protein aggregates, based on untargeted mass spectrometry proteomics, and used to map tau modifications. 🧪 🧠 @natprot.bsky.social www.nature.com/articles/s41...

Today is an important day for us as a journal. We publish a Comment that analysis the gender of last authors of Nature Physics papers over the last decade ($): www.nature.com/articles/s41... Many thanks to Alannah Hallas for taking the time to collect the data and write the piece.

A phototheranostic nanoparticle formulation for the simultaneous diagnosis and therapy of pulmonary tuberculosis in mice achieved by coating the phototheranostic agents with preactivated macrophage membranes. 🧪 #immmunosky @natprot.bsky.social

We have officially kicked off our #NatureConference here in Wenzhou, China. It's a pleasure to be here in beautiful Wenzhou! I am excited to learn 🤓

And this, dear readers, is why you should never embed figures in your docs! 🤣 🤣 🤣 🧪 #editorslife

Our April issue is live! 🌧️🌷 nature.com/nmeth/volume... On the cover, Spotiphy projects scRNA-seq and histological image data onto the spatial transcriptome. Artwork by Jiyuan Yang @stjuderesearch.bsky.social. Paper: www.nature.com/articles/s41...

Bronwen Dekker, Senior Editor at Nature Protocols, will be at the EMBO workshop on climate resilience online next week. Don't miss this opportunity to learn from experts! Sign up here: