Major cool membrane conference coming up next week! The Biomembrane Days 2025, organized by an amazing team from the MPI for Colloids and Interface Science @mpici.bsky.social: Rumy Dimova (@dimovalab.bsky.social), Helge Ewers, and Thomas Weikl. I'm so very much looking forward to attending! 🤩 🧪

One of the important benefits of @reviewcommons.org is having a peer-reviewed preprint, which to an increasing number of funders counts as a published paper @embo.org Saves important time for trainees to have their work recognized.

Version of Record Structural basis for mTORC1 activation on the lysosomal membrane www.nature.com/articles/s41...

Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou

Previous preprint is now published in RSC Chemical Biology. If you are interested in plasma membrane labeling, see the paper! 👇 pubs.rsc.org/en/content/a...

Join us in celebrating the #ASBMB26 Award Winners! • @abu-remaileh.bsky.social • Suzanne Barbour • @bradylabupenn.bsky.social • George Carman • Joseph Cotruvo • Roger Davis • @rolanddunbrack.bsky.social • Pamela Mertz • @olzmannlab.bsky.social • Kim Orth • Margaret Phillips ow.ly/x05f50WSbax

What allows lamins A and C to confer much stronger mechanical stability to the nuclei than lamin B? We show that even though all lamins can protect the nucleus from small cell intrinsic forces, only lamin A/C protect the nucleus from large deformations: www.biorxiv.org/content/10.1... 1/n

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio meetings.embo.org/event/26-org...

Honored to be elected an EMBO Member — a milestone that coincides with the 10th anniversary of my lab at ENS Physics in Paris. Grateful to the brilliant students and postdocs who shaped this collective journey. I share this with all of you! bsky.app/profile/embo...

Welcome and congratulations to the 60 new members and 9 associate members who have been elected to the EMBO Membership! This honour celebrates #research excellence and outstanding achievements in the #LifeSciences. 🧪 Learn more here: www.embo.org/press-releas... #EMBOMembers2025

Out today, we report how small chemical modifications in the metabolism of ergosterol are needed for yeast membranes to phase seperate into ordered yet fluid domains www.science.org/doi/10.1126/... (1/n)

We , @lbm-epfl.bsky.social and @gisouvggoot.bsky.social #EPFL together with and tf Sean Munro and John Briggs have today released two complementary preprints on GOLPH3 mediated intra-Golgi recycling #CellBiology #MembraneTrafficking www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

🚨Our paper is out! If you ever wonder how four-way junctions are avoided during plant cell division, some answers here 🧬🍀🔬🧪🤓 👇 www.sciencedirect.com/science/arti...

Happy to see our highlight out discussing new findings related to NADH and FSP1 compartmentalization in ferroptosis. Lead by two terrific postdocs Amalia Megarioti and Kirandeep Deol! 🤩 👏 www.cell.com/current-biol...

Very glad and honored to contribute to this cool study. Check out the latest story on my favorite protein "NINJ1": www.nature.com/articles/s41...

Excited to share our latest preprint! Using integrated global lipidomics and proteomics, we show that SARS-CoV-2 variants induce conserved changes in host lipid metabolism pathways. Congrats to Scotty for leading the work. @ohsummi.bsky.social @ohsunews.bsky.social www.biorxiv.org/content/10.1...

Thrilled this paper is out! We solved the first cocrystal structure of FSP1 with an inhibitor (FSEN1), providing mechanistic insight & a foundation for medchem. Led by Amalia Megarioti & Sitao Zhang. A terrific collaboration with Da Jia. Brief Skytorial! 1/9

Our joint paper with Wonpil Im lab is now available as a preprint: "Dynamic Architecture of Mycobacterial Outer Membranes Revealed by All-Atom Simulations" www.biorxiv.org/content/10.1...

🚨 URGENT RESPONSE CALL 🚨 Trump’s Fool’s Gold Science EO is a dangerous sham. It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda. We’ve launched an open letter. SIGN & SHARE NOW: actionnetwork.org/petitions/op...

A condensate-based approach reversibly sequesters lipid droplets (LDs) in cells, temporarily halting their functions and enabling detailed study of LD biology and the interactions of LDs with other cellular structures www.nature.com/articles/s41...

What if we could trap Lipid Droplets and control their dynamics in cells? Our latest work does just that, using Engineered Condensates to manipulate LD behavior. Exciting results by Chems Amari and the team! Great collab with ‪@abdourachidthiam.bsky.social‬ #Organelles #Condensates rdcu.be/emYpU

Early for #MicroscopyMonday: #Hemifusomes- Newly discovered ESCRT-independent intermediates of intraluminal vesicle and multivesicular body formation! In collaboration with the Kachar Lab at the NIH and out today in @natcomms.nature.com : rdcu.be/emtQu #cryoET #trafficking #organelle #hemifusion

Why do the brain’s professional phagocytes stop clearing amyloid in Alzheimer’s disease? Can we restore microglial superpowers & rescue dying neurons in AD? YES, by stopping DGAT2-mediated lipid droplet formation! Checkout our latest manuscript @cp-immunity.bsky.social 👇🏼 www.cell.com/immunity/abs...

Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...

Flocking and active solid behavior of epithelial cells in our new study in @pnas.org Great work of Y. Shen, J. O'Byrne and @andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez! | PNAS www.pnas.org/doi/10.1073/...

Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis: Molecular Cell www.cell.com/molecular-ce...

Our lab at the NIH (Bethesda, MD) is looking for postdoctoral fellows to join our team studying the molecular mechanisms of protein trafficking and their links to neurodevelopmental disorders starting on or after 10-1-2025. Send your application to [email protected]. Please share and repost!

Thank you very much @abdourachidthiam.bsky.social for kicking off the 2025 Stanford BioE colloquium @bioe-stanford.bsky.social! We had a blast learning about cellular lipid droplets and seeing all the creative ways you combine cell biology, chemistry and physics!!!

Important to celebrate trainee victories: excited to have Holly Merta's @hollymerta.bsky.social paper out! We use TurboID sub-organelle proteomics to map the ER network. We find calmin/CLMN, an ER-to-actin tether regulating focal adhesions & cell motility. www.sciencedirect.com/science/arti...

I am thrilled to announce my and @giuliazanetti.bsky.social's latest review "Mechanisms of COPII coat assembly and cargo recognition in the secretory pathway" in @natrevmcb.bsky.social with @springernature.com. Check it out here! rdcu.be/eeY1J #COPII #CryoEM #TeamTomo #MembraneTrafficking #ERES

Registration has started for the conference "Emerging Trends in the Physics of the Cell" in memoriam of Erich Sackmann at TU Munich from October 15-18 2025 www.cpa.tum.de/cpa/conferen...

PINK1/Parkin-dependent mitophagy caught in situ by cryo-ET! New preprint www.biorxiv.org/content/10.1... led by @kev-in-situ-et.bsky.social. This has been a long-standing goal of team @mito911.bsky.social within the @asapresearch.parkinsonsroadmap.org initiative.

📢 Last days to register !! Join us to the 27th meeting of the Club Exo-Endo from May 5 to 7 at Fort-Mahon. exoendo.org/en/evenement...

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry: Cell www.cell.com/cell/fulltex...

Groundbreaking study in Cell from @leventallab.bsky.social: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes — major implications for how this membrane works. A #lipidtime must-read! www.cell.com/cell/abstrac...

Amazing microscopy from Bewersdorf/Rothman groups shows golgins in a striking four-layered structure at the Golgi rim. Biochemical reconstitution shows long filaments. Does a Golgi stack form due to golgin filament properties rather than dedicated stacking proteins? www.biorxiv.org/content/10.1...

STAR/STARD1: a mitochondrial intermembrane space cholesterol shuttle degraded through mitophagy www.biorxiv.org/content/10.1...

BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM www.biorxiv.org/content/10.1...

We are happy to announce that the registration for the 27th annual meeting of the Exocytosis-Endocytosis Club is still open! NEW REGISTRATION DEADLINE : APRIL 4 by following the link below. exoendo.org/evenement/27... 🙏@gdrimabio.bsky.social @sbcf.bsky.social for support!

Finally moved to #Bluesky and happy to share our recent work! We found that hexokinase 1 rapidly forms rings around #mitochondria during energy stress to regulate mitochondrial fission: www.cell.com/molecular-ce... For a quick summary of our findings, check out the comment section.