MBoC Highlight: Quantitative Cell Biology June 22 | 12 PM ET Keynote: Jennifer Lippincott-Schwartz + emerging research from the special issue. Register: https://www.ascb.org/ascb-meetings/mboc-highlight-quantitative-cell-biology-with-keynote-by-jennifer-lippincott-schwartz/

Beyond delighted to share our amazing collaboration with Thierry Alquier's lab @alquierthierry.bsky.social on a conserved role for neuronal lipid droplets in regulating energy homeostasis in vivo led by Celena Cherian, Romane Manceau, Danie Majeur, and Colin Miller www.nature.com/articles/s42... /1

The reticulon homology domain of Pex30 generates membrane curvature at ER subdomains for lipid droplet biogenesis www.biorxiv.org/content/10.6...

Our paper is now out in Science! Super excited to share our discovery that #mitochondria #pearling is the elusive mechanism driving the regular distribution and inheritance of #mtDNA nucleoids 🧬 [1/6]

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...

I am extremely excited that my first first-author paper from my PhD is finally out 😆!! We developed a new CLEM workflow to measure lipid densities at the nanoscale. So if you are into lipids and super-resolution imaging approaches, this one is for you: www.nature.com/articles/s41...

I’m so happy to join the Editorial Board of JCB! I look forward to handling your manuscripts

1/9 🚨 New paper out in Nature Metabolism! Chapter 2 of our mitochondria zonation story (following our 2024 Nature Communications work). We asked how zonated liver mitochondria adapt when lipid flux surges. 🧵👇 www.nature.com/articles/s42...

Awesome paper and super useful resource of CRISPR-based screens to identify regulators of #LipidDroplet biology under different metabolic conditions: crisprlipid.org

Sooo happy to share our new paper in @nature.com “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” A terrific collaboration with @arrudalab.bsky.social, led by co–first authors Alyssa Mathiowetz and Emily Maymand. www.nature.com/articles/s41...

Thrilled to share that the first part of my PhD work from @cohenlaboratory.bsky.social lab is now on bioRxiv! www.biorxiv.org/content/10.6... Check out the threads below:

I'm delighted to present TWO new preprints from my lab, led by @mczanellati.bsky.social and @sherryhsu.bsky.social, about how #organelles remodel throughout #NeuronalDifferentiation. Check out the threads about their papers below:

During #NeuronalDifferentiation, #organelles dramatically reorganize. #Microtubules are essential tracks for transport. But are they just highways, or can they instruct organelle behavior? Are tubulin modifications a regulatory code that guides organelle position or function? 1/9

Cells come in many shapes and sizes, with diverse physiological functions. But how do #organelles and their interaction networks remodel during #differentiation of stem cells into different cell types? Here’s what we discovered about neuronal differentiation: 1/13

Our new paper's out: FidlTrack—structure-aware single-particle tracking benchmarks/boost SPT fidelity With it we resolve with sub-organelle res. e.g. BACE1 amyloidogenic APP cleavage #Alzheimers, ER exit events, map nanobody binding in realtime in ER/organelles 🔬🧠#SingleMolecule rdcu.be/e3Ris

Huge congrats to @manuelthery.bsky.social and all the Cytomorpho lab. The "Living Architectures" performance at @museeorsay.bsky.social was breathtakingly beautiful

Have a look (and read) at our newest Review below! 🥳 Great discussion on how lipid droplets interact with other organelles, written by @cohenlaboratory.bsky.social and @hennelab.bsky.social

With so many great reviews on LDs already out, do we need another? Sarah @cohenlaboratory.bsky.social and I were approached by @natrevmcb.nature.com to do a review on LD heterogeneity and inter-organelle contacts...topics in reviews, but not a focus. Fun project! www.nature.com/articles/s41...

Such a pleasure to write this review on #LipidDroplet heterogeneity, dynamics and #organelle interactions with Mike @hennelab.bsky.social ! Thank you to the editorial team @natrevmcb.nature.com and to Yoni Malis for assistance with draft illustrations

New Online! Heterogeneity, dynamics and organelle interactions of lipid droplets

Registration is open for the FASEB #LipidDroplet meeting in Scottsdale, July 26-30! This is THE premier North American conference on LDs, you do not want to miss it!

Interested in lipids? Join us @ the 2026 FASEB Lipid Droplet: From Mechanisms to Disease Conference (July 26-30, Scottsdale, AZ). Registration is now open! events.faseb.org/event/Lipid-... We are co-locating with the FASEB Phospholipids SRC! Register for one to enjoy BOTH meetings!

In their Editorial, Claire Moulton, Amelia Glazier and Katie Ward look back on an extraordinary year, as @biologists.bsky.social celebrated their 100-year anniversary. journals.biologists.com/jcs/article/...

In parallel, we'll be publishing a special issue on Imaging Cell Architecture and Dynamics - you can find out more at: journals.biologists.com/jcs/pages/im... Submission deadline: 1 April 2026 #imaging #microscopy #cellbiology

Registration for our Imaging Cell Dynamics meeting is still open! Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social and @giuliazanetti.bsky.social. Find out more: www.biologists.com/meetings/jcs... Early-bird deadline: 16 January #imaging #microscopy

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Ups we did it again! Please mark your calender. EMBO Workshop “Lipid Code to Life”, taking place September 7–11, 2026, in Dresden, organized by Maria Fedorova, @lipid.bsky.social, Valerie O'Donnell, @holthuislab.bsky.social and @molcellbiophys-lab.bsky.social 🥳 Retweets = lipidlove

😢😢😢

#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.

Attending #CellBio2025? Come see the Cohen Lab - Monday will be a busy day for us, including my theatrical debut in WICB "Scripts of Success" skits!

Our annual collection highlights 13 of the year's most impactful papers that have garnered exceptional interest from our readership. Explore cutting-edge findings spanning the diverse spectrum of cell biology 👉 rupress.org/jcb/collecti... #CellBio2025 @ascbiology.bsky.social

Check out our @ascbiology.bsky.social #CellBio2025 Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself! So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)

Ithaca is gorge-ous! Thank you @fromme-lab.bsky.social, @jeremybaskin.bsky.social and colleagues for a very fun and stimulating visit to the Weill Institute for Cell and Molecular Biology at Cornell!

Happy Halloween from the creative minds of CBP grad students and scientists!!

It was great to finish off #UNCResearchWeek by seeing Sherry Hsu’s beautiful image on display in Bondurant Hall! 🔬🔬🔬

Here's the link to the system, try it! qedscience.com @qedscience.bsky.social

It’s clear we need alternatives or at least ways to improve the situation. So, together with a really special and talented team we worked to develop this idea into “qed” a platform where you can get CONSTRUCTIVE feedback on your own work or CRITICALLY assess other people’s papers.

Looking forward to #UNCResearchWeek! I'll be presenting my lab's work on #organelles in physiology and neurodegenerative disease on Monday, October 20

Genuinely thrilled to share our new story with the world - an amazing collaboration with @profsharona.bsky.social and Bill Zagotta using their innovative FRET technique to study mitofusin conformational changes. Huge credit to Sophie Hurwitz for tackling this project. urldefense.com/v3/__https:/...

Time for a thread!🧵 How different is the molecular organization of thylakoids in “higher” plants🌱? To find out, we teamed up with @profmattjohnson.bsky.social to dive into spinach chloroplasts with #CryoET ❄️🔬. Curious? ..Read on! #TeamTomo #PlantScience 🧪 🧶🧬 🌾 elifesciences.org/articles/105... 1/🧵

Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...

This is another must read - great week for organelle bio tools this week!

Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou

This is going to be a very exciting meeting!! 🔬🧫🌈

Registration is open for our Imaging Cell Dynamics meeting. Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging. For more info: www.biologists.com/meetings/jcs...

A pleasure to write this short review on lipid droplets for @jcb.org together with Will Prinz and amazing artist Emma Reynolds! We discuss 5 pervasive questions surrounding these remarkable little lipid organelles. doi.org/10.1083/jcb....

new preprint from @iostephens.bsky.social describes the potential benefits of increasing lipid turnover in microglia by eliminating PLIN2 from their surface