Now published in NSMB! Paper: doi.org/10.1038/s415... Full PDF: rdcu.be/fhBtI Overview of additions since the preprint👇 (1/5)

A picture is worth a thousand words. What’s your favorite photo from the SNSF Scientific Image Competitions of the last 10 years? 🧪🧬🔬 www.snf.ch/en/1uKR6zjXH... @snsf.ch

🔍 How did we support Swiss research last year? And what were the results? The SNSF’s #AnnualReport 2025 presents graphics, facts and figures.💡 ➡️ sohub.io/amni

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Let the truth be told, let the press be free. 📰 Journalists give a voice to the voiceless, hold power to account, and shine a light in the darkest corners of society often at great personal risk. Too many face intimidation, censorship, and violence simply for doing their job.

My book BEYOND BELIEF is out today! It says: in a world flooded with questionable claims and misinformation, evidence from science can help show what’s nonsense – and what’s not. In other words: "Essential reading for the rational-minded". Please repost! 1/🧵 @princetonupress.bsky.social

1902 publiziert, 100 Jahre nahezu ignoriert, heute ein Klassiker mit über 2.250 Zitierungen. William Bayliss' Paper zur myogenen Reaktion wäre im heutigen System des #PublishOrPerish als wertlos aussortiert worden. Was das über moderne Wissenschaft verrät: www.laborjournal.de/blog/?p=1492...

The CASP experiment is about to start - and is still short on challenging prediction targets. Ligand complexes, RNA, …

The Summer Call for our prestigious, fully funded #PhDFellowships is now open to talented early-career scientists worldwide. 🔬 Rotation-based program 🌍 International community 🗓 Apply by May 8, 2026 Apply now and join a leading life sciences institute! www.biozentrum.unibas.ch/phd/internat...

This is why I’m not allowed in the wet lab anymore 🥼 🕺. My technique is too effective! 🤪 #PILife #TeamTomo 🧪

Sad news on the passing of Prof. Andreas Engel, a pioneer in the field of cryo-EM (shared with the 3DEM community by Henning Stahlberg). Andreas' kindness, warmth, and enthusiasm for science and his colleagues will be missed.

Call for Targets: CASP17 (2026) Depositors: Help advance the frontiers of structural biology by submitting your targets

It's hard to describe how valuable CASP is to the structural biology & structure prediction field. The ever increasing number of prediction algorithms means independent assessment of their accuracy is vital. Please contribute interesting/tricky structural data if you can!

Research data is the foundation of almost all academic disciplines. Reliable access to this data is increasingly at risk. A working group of the DFG Senate has identified key risks & put forward recommendations to strengthen resilience, digital sovereignty & sustainable preservation.⏬ sohub.io/rda3

Congratulations to the awardees of the @sib.swiss Remarkable Outputs from 2025 - the submissions were of such high-quality it was really difficult to select the most remarkable! www.sib.swiss/news/discove...

Some first-rate science writing: For this story, @jdrakephd.bsky.social carefully read our recent paper and then we spent a very fun 90 minutes or so talking on zoom. His article that gets right to the heart of our model, explains it clearly, and then explores why it will matter in the future.

Open Research Europe is stepping into an exciting new chapter to become a truly collective European diamond open access platform: Backed by 16 national funders and research institutions and continued European Commission involvement, ORE will be hosted by CERN in Geneva. home.cern/news/news/kn...

📣 Call for proposals: The SNSF and the Australian National Health and Medical Research Council (NHMRC) are launching a call on the topic of artificial intelligence (AI) in healthcare. 📆 Submission deadline: 17 June 2026 ➡️ sohub.io/dhxs

⁉️ The SNSF is reforming its career funding. A new postdoctoral funding scheme will be launched in 2028 to replace both Postdoc.Mobility and Ambizione. The aim is to offer greater flexibility and a high level of autonomy. For more info ➡️ sohub.io/lnsa

Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬 Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes. The Rule of Thumb: If AF3 can’t model it, we want it.

Stoic 🦾 from our shared student @daniil-litvinov.bsky.social predicts protein complex stoichiometry. A fun collab with @ninjani.bsky.social @torstenschwede.bsky.social - this #AI adventure beyond our core #CryoET methods was made possible by the @biozentrum.unibas.ch PhD Fellowship Program! 🧪 🧶🧬

Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬 Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes. The Rule of Thumb: If AF3 can’t model it, we want it.

🚄⚡🔋 Till Ruemenapp, Head of Corporate Research in Switzerland for the leading electrical engineering and technology company ABB, describes the productive collaboration between basic research and industry that is driving progress towards the future. For more info: sohub.io/64uw

From spring 2026, Switzerland will support six new National Centres of Competence in Research (NCCRs). In an interview, @snf-fns.ch Research Council President Torsten Schwede explains how projects are selected and why the new NCCRs matter for Switzerland’s research landscape ⬇️

PDB Reaches a New Milestone: more than 250,000 entries

Happy Birthday #AFM! To celebrate the first description of the atomic force microscope (AFM) in Physical Review Letters, we spoke to our longstanding honorary member Christoph Gerber, who, together with Carl Quate and Gerd Binnig, invented this groundbreaking instrument. @unibas.ch bit.ly/4raqCOm

🇪🇺 At a key moment for Europe’s R&I future, Science Europe gathered policymakers and researchers for a breakfast dialogue at the @europarl.europa.eu, hosted by @linagalvez.eu, to discuss #FP10 priorities: strong budget, simpler rules, excellence, inclusion & open collaboration. #ResearchPolicy

Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme? Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues. Apply by 16 MAR www.nature.com/naturecareer...

Swiss session at the AI Impact Summit in Delhi. Excellent panel discussing on “Breaking Barriers: multilingual AI as a Bridge to Democractic Access”.

Deadline approaching for nominations for the Marcel Benoist Swiss Science Prize:

The legacy of Amos Bairoch, the resources he and others created (Swiss-Prot, UniProt, PROSITE, ENZYME, ExPASy, neXtProt, Cellosaurus), his commitment to open access and high-quality curation, is immense and have guided bioinformatics to this day.

We recently released The Embedded Alphabet (TEA), a tiny head on top of ESM2 converting amino acids into a new 20-letter structural alphabet. Great for search (see bsky.app/profile/lore...), but we wondered: could we use it for generation? (2/n)

Bundespräsident Parmelin lanciert sechs neue Nationale #Forschungsschwerpunkte in Medizin, Klima, Physik und Chemie. Der #Bund stellt bis 2029 über 98 Mio. CHF bereit und die #Hochschulen steuern zusätzliche Mittel bei. Ziel ist die Förderung von Exzellenz und Stärkung der internationalen Position.

Le président Guy Parmelin lance six nouveaux #Pôles de recherche nationaux en médecine, climat, physique et chimie. La #Confédération alloue plus de 98 millions CHF jusqu’en 2029, auxquels s’ajoutent des moyens des #hautes écoles. But : renforcer l’excellence et la position internationale de la CH.

Il presidente della Confederazione Parmelin lancia 6 nuovi #poli nazionali di ricerca in settori come medicina, clima, fisica e chimica. La #Confederazione stanzierà oltre 98 mio. fr. fino al 2029; le #scuole universitarie forniranno ulteriori fondi. Obiettivo: promuovere l’eccellenza Svizzera.

Federal President Parmelin launches six new National #Centres of Competence in Research in medicine, climate, physics and chemistry. The #Confederation has set aside over CHF 98 million to be spent between now and 2029 and additional funding will be provided by #higher education institutions.

Six new National Centres of Competence in Research #NCCR announced today in strategically important areas such as medicine, quantum technology and climate: Children & Cancer, CLIM+, Genesis, Muoniverse, Precision, and Separations. www.wbf.admin.ch/en/newnsb/JE... @snsf.ch @sbfi.admin.ch

Forschungsförderung ist ein wichtiger Teil unserer Zukunftsvorsorge. Österreich investiert in den nächsten 3 Jahren 3 Mrd € in die Grundlagenforschung. Ein reales Wachstum - selbst angesichts der hohen Inflation der letzten Jahre 👏 www.derstandard.at/story/300000... @sbfi.admin.ch @snsf.ch 🧪

Europa muss souveräner werden bei wissenschaftlichen Daten und Forschungsressourcen – aus Verantwortung. Darüber habe ich in dieser Woche im Deutschlandfunk gesprochen ⬇️ www.deutschlandfunk.de/us-wissensch...

Congratulations to the Ypsomed Innovation Award winners 2026 !🏆 Visienco Rhovica Neuroimaging optohive www.linkedin.com/company/ypso... #YpsomedInnovationAward 𝗕𝗮𝘀𝗶𝗰 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝘁𝗼𝗱𝗮𝘆 🤝 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝘁𝗼𝗺𝗼𝗿𝗿𝗼𝘄

“We need to ask ourselves, on both sides of the Atlantic, if we want to live in a world where democracy is recast as weakness, truth as opinion and justice as an option.” Alain Berset in NYT: www.nytimes.com/2026/01/19/o...

Excellente tribune de @torstenschwede.bsky.social à propos de l'importance de soutenir le @snf-fns.ch www.letemps.ch/opinions/inv... www.letemps.ch/opinions/inv...

The 2026 Marcel Benoist Swiss Science Prize will be awarded in the field of life sciences (biology and medicine). 🧪 Deadline for nominations: 23 February 2026. marcel-benoist.ch/en/nominatio... @snsf.ch

🚀 New paper in @natmethods.nature.com! We present OpenStructure's powerful scoring capabilities, used to assess predictionsin CAMEO and CASP. Read the full study here: 🔗 doi.org/10.1038/s415... #StructuralBiology #Bioinformatics #OpenStructure #CASP #CAMEO #ProteinStructure

Shaping the future of research funding. 🧪 The @snsf.ch Swiss National Science Foundation is looking for new members for the Foundation Council. Application deadline: 30 January 2026. www.snf.ch/en/Boii3zvoj...

Good morning Basel! @unibas.ch

The SNSF is considering restrictions for its Project funding. Goal: to ensure the quality of evaluation & stable success rates despite an increasing number of applications and limited funding. The final decision will be made in January 2026. 👉 buff.ly/iGOCf7R #research #science

Interesting study showing how genetic variation can limit antibody therapies, led by the DBM team (Lepore & Jeker) with computational structural analysis from @torstenschwede.bsky.social @biozentrum.unibas.ch www.biozentrum.unibas.ch/news/detail/... #PrecisionMedicine #Genetics #AntibodyTherapy

Antibody-based therapies are used to treat numerous diseases, from cancer to rheumatic disorders and multiple sclerosis. Researchers @biomedizin.unibas.ch & @biozentrum.unibas.ch now report that individual genetic differences can prevent antibody-based therapies from being effective in some people.

The administration of US President Donald Trump intends to dismantle the National Center for Atmospheric Research (NCAR), a world-leading Earth-science centre in Boulder, Colorado. go.nature.com/4pjzUqB